한국 성인남성에서 연령과 전립선 용적 보정 후 PSA에 영향을 미치는 인자

고재이,양원재,송윤섭,박영호 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.5

Purpose: We investigated the influence of the anthropometric and serological parameters on the prostate-specific antigen(PSA) levels after adjusting for age and the prostate volume in Korean men who visited a health promotion center. Materials and Methods: From January 2004 to July 2007, among the 18,352 men(age range: 30 to 79) who visited our health promotion center for general check-ups, 1,230(14.9%) men who wanted their prostate evaluated were included in this study. Thereafter, 151 men whose PSA level was over 4.0ng/ml, or their urinalysis revealed pyuria(>5 white blood cells (WBCs)/high power fields(HPF)) were excluded. The data of the remained 1,079 men was then analyzed. All the men underwent transrectal ultrasonography, detailed anthropometric measurements and serological tests. The correlation of the PSA level with the various anthropometric and serological parameters was investigated. Results: On the univariate analysis after adjusting for age and the prostate volume, the PSA level showed statistically significant positive correlation with the WBC, the red blood cell(RBC) and platelet(PLT) counts/μl, and the PSA level was negatively correlated with height, weight, the body surface area(BSA), the body mass index(BMI), γ-glutamyltransferase (GGT), and creatinine clearance(Ccr). On multivariate analysis, age, the prostate volume and the RBC/PLT counts/μl were positively correlated with the PSA level, and the BSA was negatively correlated with the PSA levels, whereas the BMI was not. Conclusions: Irrespective of age, the prostate volume and the BSA were the independent factor influencing the PSA level, that is, the larger the BSA, the lower the PSA. (Korean J Urol 2008;49:411-417) Purpose: We investigated the influence of the anthropometric and serological parameters on the prostate-specific antigen(PSA) levels after adjusting for age and the prostate volume in Korean men who visited a health promotion center. Materials and Methods: From January 2004 to July 2007, among the 18,352 men(age range: 30 to 79) who visited our health promotion center for general check-ups, 1,230(14.9%) men who wanted their prostate evaluated were included in this study. Thereafter, 151 men whose PSA level was over 4.0ng/ml, or their urinalysis revealed pyuria(>5 white blood cells (WBCs)/high power fields(HPF)) were excluded. The data of the remained 1,079 men was then analyzed. All the men underwent transrectal ultrasonography, detailed anthropometric measurements and serological tests. The correlation of the PSA level with the various anthropometric and serological parameters was investigated. Results: On the univariate analysis after adjusting for age and the prostate volume, the PSA level showed statistically significant positive correlation with the WBC, the red blood cell(RBC) and platelet(PLT) counts/μl, and the PSA level was negatively correlated with height, weight, the body surface area(BSA), the body mass index(BMI), γ-glutamyltransferase (GGT), and creatinine clearance(Ccr). On multivariate analysis, age, the prostate volume and the RBC/PLT counts/μl were positively correlated with the PSA level, and the BSA was negatively correlated with the PSA levels, whereas the BMI was not. Conclusions: Irrespective of age, the prostate volume and the BSA were the independent factor influencing the PSA level, that is, the larger the BSA, the lower the PSA. (Korean J Urol 2008;49:411-417)

17세 청소년에서 발생한 방광요로상피종양

고재이,권계원,고은석,이광우,김준모,김영호,김민의 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.2

Urothelial neoplasms in patients younger than 20 years old are extremely rare, and there is no established etiology, treatment guidelines, or surveillance for urothelial carcinoma in the pediatric population. A 17-year- old boy who presented with gross hematuria showed a smooth, round mass on the left lateral wall of the urinary bladder on cystoscopy. Histologic examination showed low grade papillary urothelial carcinoma of the urinary bladder without muscle layer invasion. We report a case of papillary urothelial carcinoma of the urinary bladder in a pediatric patient treated with transurethral resection. (Korean J Urol 2008;49:190-192)

게임 스토리텔링에 기반한 웹게임 연구 : 삼국지를 중심으로

고재이,강효순 한국게임학회 2015 한국게임학회 논문지 Vol.15 No.1

본 연구는 웹 게임 스토리텔링이 갖는 의미와 발전방향에 대해 논한다. 디지털 문화 산업은 기술혁신에 의해 성장을 거듭하고 있다. 그러나 웹 게임 스토리텔링은 기술적 발전보다 덜 주 목 받고 있다. 온라인 게임 산업의 미래가 클라우드 환경에 기반한 웹 게임 이라고 보고, 웹 게 임의 성장을 위해서 스토리텔링이 얼마나 중요한지 연구해보고자 한다. 국내 웹 게임의 대표작 인 ‘삼국지를 품다’를 성공사례로 하여 배경 스토리인 ‘삼국지 연의’가 웹 게임과 만나 어떤 상 호보완적 관계를 이루었는지를 분석하여 웹 게임 스토리텔링의 방향성을 제시해보고자 했다. The meaning and development direction of storytelling of web game will be discussed in this study. The digital culture industry is getting grow more and more by technology innovation. But web game storytelling attracts attention less than technology development. So assuming that the future of game industry is depend on web game based on cloud environment, how much important the storytelling is for growth of web game will be studied. Taking ‘Embracing Three Kingdom’ as success case, which is representative web game in this country, the direction of web game storytelling will be suggested by analyzing ‘Romance of the Three Kingdoms’, which is back ground story of it, met web game and what complementary relationship made with it.

게임 스토리텔링에 기반한 웹게임 연구

고재이(Ko, Jay),강효순(Kang, Hyosoon) 한국게임학회 2015 한국게임학회 논문지 Vol.15 No.1

본 연구는 웹 게임 스토리텔링이 갖는 의미와 발전방향에 대해 논한다. 디지털 문화 산업은 기술혁신에 의해 성장을 거듭하고 있다. 그러나 웹 게임 스토리텔링은 기술적 발전보다 덜 주목 받고 있다. 온라인 게임 산업의 미래가 클라우드 환경에 기반한 웹 게임 이라고 보고, 웹 게임의 성장을 위해서 스토리텔링이 얼마나 중요한지 연구해보고자 한다. 국내 웹 게임의 대표작인 '삼국지를 품다'를 성공사례로 하여 배경 스토리인 '삼국지 연의'가 웹 게임과 만나 어떤 상호보완적 관계를 이루었는지를 분석하여 웹 게임 스토리텔링의 방향성을 제시해보고자 했다. The meaning and development direction of storytelling of web game will be discussed in this study. The digital culture industry is getting grow more and more by technology innovation. But web game storytelling attracts attention less than technology development. So assuming that the future of game industry is depend on web game based on cloud environment, how much important the storytelling is for growth of web game will be studied. Taking 'Embracing Three Kingdom' as success case, which is representative web game in this country, the direction of web game storytelling will be suggested by analyzing 'Romance of the Three Kingdoms', which is back ground story of it, met web game and what complementary relationship made with it.

전립선과 항문주위 농양에 병발된 폐렴막대균에 의한 내인성 안구염

정태성,김근우,고재이,양원재,김태형,최경식,송윤섭,박영호 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.11

Endogenous endophthalmitis is a sight-threatening ophthalmic emergency that requires vitrectomy unless prompt treatment is undertaken. It is usually caused by hematogenous spread from a distant endogenous focus of infection. We treated a patient with endogenous endophthalmitis who also had prostate and perianal abscesses caused by Klebsiella pneumoniae. Clinicians should entertain the possibility of endogenous endophthalmitis if a patient with a urologic disease such as a prostate abscess or acute prostatitis resulting in bacteremia complains of ophthalmologic symptoms.

건강한 중년여성에서 생선 가시 섭취에 의해 발생한 국소적 위벽 농양 1예

고상훈,이계성,고재이,윤형식,김성근,김성호,박찬우,남관우 대한소화기내시경학회 2011 Clinical Endoscopy Vol.42 No.2

Gastric wall abscess is a one form of phlegmonous gastritis and there are scare reports on this. Gastric wall abscess is a purulent inflammatory disease and it is commonly caused by a focal injury to the gastric mucosa such as a penetrating trauma from an ingested foreign body or an endoscopic biopsy where by bacterial infection occurs throughout all the layers of the gastric wall. With symptoms such as abdominal pain and fever, making the diagnosis after an operation was possible in the past, but it has recently become possible to make the diagnosis before the operation via esophagogastroduodenoscopy, endoscopic ultrasonography and/or abdominal computed tomography. We recently experienced a case of gastric wall abscess that was associated with a foreign body (presumably a fish bone) in a healthy middle aged woman. By performing generalized esophagogastroduodenoscopy and abdominal computed tomography at a primary medical institution, we made an early diagnosis and treated the patient. Herein, we report on this case and we review the relevant literature. 위벽 농양은 봉와직성 위염의 한 형태로 매우 드물게 보고되고 있다. 위벽 농양은 흔히 이물질의 섭취나 내시경적 용종절제술에 의해 위점막이 손상되고 이후 세균에 의해 점막하층에서부터 시작하여 위벽 전층에 이르기까지 화농성 염증이 초래되는 질환이다. 심와부 동통, 발열 등의 임상증상과 예전에는 수술 후 진단이 가능하였으나 최근에는 상부위장관 내시경, 내시경초음파, 복부 전산화 단층촬영을 통해 수술 전에도 조기 진단이 가능해졌다. 최근 저자들은 건강한 중년 여성이 생선 가시로 추정되는 음식물 섭취 후 발생한 국소적 위벽 농양에 대해 상부위장관 내시경 및 복부 전산화 단층촬영을 통해 조기 진단 및 치료를 시행한 1예를 경험 하여 문헌고찰과 함께 보고한다.

유기인계농약 중독환자에서 급성췌장염의 합병증으로 인해 뒤늦게 발생한 급성 폐손상 1례

윤형식,이연선,고상훈,고재이,김성근,김성호,박찬우,송치호 대한응급의학회 2011 대한응급의학회지 Vol.22 No.4

Organophosphate insecticides are used globally and are household items in rural areas of Korea. Their ingestion for a suicidal purpose is common in Korea. Respiratory failure is the most serious manifestation and the usual cause of death in acute organophosphate poisoning, and is usually common during acute cholinergic crisis. But, respiratory failure may appear suddenly in a patient who is recovering from a cholinergic crisis, even while receiving conventional therapy. Most of these respiratory failures are associated with intermediate syndrome or pneumonia. In several recent studies, acute pancreatitis as a complication of organophosphate poisoning has been shown to be not a rare condition and respiratory failure may also occur in acute pancreatitis. However, acute lung injury developing as a complication of organophosphate intoxication-induced pancreatitis has not been hitherto reported in Korea. We described a case of a 50-year-old woman who had acute organophosphate intoxication-induced acute pancreatitis. The patient developed acute lung injury on the eighth day hospital day, after cholinergic crisis, without intermediate syndrome and pneumonia. Exclusion of other causes indicated that the acute lung injury may have developed due to acute pancreatitis.

포스터 전시 발표 순서 : 호흡기 ; 폐부종과 동반되어 늦게 진단된 속립성 결핵 (초)

정재진,박설,김굉배,고재이,고상훈,윤형식,이연선 대한내과학회 2008 대한내과학회지 Vol.75 No.1S

호흡기 : 폐부종과 동반되어 늦게 진단된 속립성 결핵 (초)

정재진,박설,김굉배,고재이,고상훈,윤형식,이연선 대한내과학회 2008 대한내과학회 추계학술대회 Vol.2008 No.-

포스터 전시 발표 순서 : 류마티스 ; 간질성 폐질환이 동반된 류마티스 관절염 환자에서 발생한 폐동맥 고혈압 1예 (초)

박설,정재진,김굉배,윤형식,고재이,고상훈,박수진,박보형 대한내과학회 2008 대한내과학회지 Vol.75 No.1S