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고재언,이정문,최태승,심왕근 한국환경기술학회 2022 한국환경기술학회지 Vol.23 No.2
In this study, we evaluate the separation performance of nitrate from water in a recycling batch type electrodialysis (ED) process. In particular, the influences of several operating parameters including the applied current densities and the concentrate concentrations on the ED process performance such as concentrate and dilute concentration profiles, % separation, and energy consumption, were experimentally and theoretically investigated. The two dimensional (2D) batch type ED model based on the extended Nernst-Planck transport theory was used to systematically understand the mass transfer in the ion exchange membrane and the influence of operating conditions on the separation performance. Our results show that the 2D model including the water transport across the membrane is useful to validate the separation of nitrate in different experimental conditions and the concentration behaviors in the concentrate and dilute channels. In addition, the separation performance of nitrate is substantially dependent on the applied current compared to concentrated inlet concentrations.
수종 지혈 한약물이 Cytochrome P450 3A4 활성에 미치는 영향
황진우,고재언,고호연,최유경,박종형,전찬용,Hwang, Jin-Woo,Go, Jae-Eon,Go, Ho-Yeon,Choi, You-Kyung,Park, Jong-Hyung,Jun, Chan-Yong 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.4
Objects : The aim of this study was to investigate the influence of five herbal medicines on cytochrome P450 3A4 drug-metabolizing enzymes in human liver microsomes. Methods : To use human liver microsomes, an extract of five herbal medicines, which are Artemisia princeps Pampan, Sophora jeponica Linne, Panax notoginseng F. H. Chen, Lithospermum Erythrorhizon Sieb., and Cirsium maackii Maxim, which together are called Jihyulyak(止血藥, drugs for arresting bleeding, hemostatics), was co-incubated and measured for relative enzyme activity in incubation condition compared to ketoconazole, a representative inhibitor of CYP 3A4. Results : We showed that all five of the traditional herbal medicines had no inhibition effect of CYP 3A4 at 10, 20, 30, 40, and $50{\mu}g/ml$ doses in human liver microsomes, although Sophora japonica Linne(SJL) showed a little inhibition at about 81% inhibition rate of control. However, this result is not enough to prove that SJL has a CYP 3A4 inhibition effect. Moreover, we can't make sure that those rates had significant induction effect on CYP 3A4. Conclusions : The result of this study could support that those herbal medicines are safer than chemical drugs, even if this is the basic step to prove that result.
청소년들의 변증에 대한 단면조사 연구 - 2017 성남시 교의사업을 중심으로 -
이동녕,신선미,박정수,성현경,고재언,고호연,Lee, Dong-Nyung,Shin, Seon Mi,Park, Jeong-Su,Sung, Hyun Kyung,Go, Jae-Eon,Go, Ho-Yeon 대한예방한의학회 2019 대한예방한의학회지 Vol.23 No.2
Objective : This study is aimed to application possibility and status of pattern identification in middle and high school students. Method : This study was cross-sectional study. We recruited 277 students through school doctor program of Seongnam city in 2017. Male students are 66 in middle school, 32 in high school. Female students are 117 in middle school, 62 in high school. For pattern identification, we used the tool of Qui Xui Shui pattern identification in students. Students fill questionnaires in inquiry of pattern identification and Korean medicine doctor diagnosis inspection and palpation of students. Results : Among 277 students, no pattern identification were 114(41.2%). It appeared in the order of phlegm, blood deficinecy, qi deficiency, qi stagnation and qi reversal. Qi deficiency, qi stagnation, qi reversal, blood deficiency and phlegm pattern are statistically significant by gender except blood stagnation. of 277 students, 105 (37.9%) had one more pattern identification. Conclusions : This study showed possibility of Qui Xui Shui pattern for student health management. In the future, large scale follow up study will be needed to clarify the relationship of pattern identification and student's health.
박정수,신선미,고호연,고재언,성현경,Park, Jeong-Su,Shin, Seon Mi,Go, Ho-Yeon,Ko, Jae-Un,Sung, Hyun Kyung 대한한방소아과학회 2018 대한한방소아과학회지 Vol.32 No.1
Objectives It is important to maintain health for students. The School Health Law is enacted in Korea to carry out the school health project like Korean Medicine Doctor's student Health and Wellness program. The purpose of this study was to examine the student's satisfaction of the program. Methods The school project was conducted in 19 schools in Seongnam city from May 2016 to December 2016. This school program was consisted of health counseling, necessary treatment, health related lectures, and vocational education about Korean medicine. A satisfaction questionnaire was conducted to gather information about overall satisfaction of the program and the program details such as health counseling, treatment, and health lectures. Results A total of 1,713 students and faculty members participated and 164 of those students completed the satisfaction survey. The overall mean score for the teaching activities was $8.54{\pm}1.76$, satisfaction of health counseling was $8.57{\pm}1.74$, treatment satisfaction was $8.39{\pm}1.83$, satisfaction with the health lectures was $8.23{\pm}1.96$ (range 3~10), and the need for continuity of the program was $8.43{\pm}1.91$ (range 1~10). One of the main benefit from the program was that students were able to get necessary treatment as soon as possible (51.2%). Conclusions We found that Korean medicine is suitable for the program. However, the large-scale prospective study will be needed for validation of the findings.
2016년도 한의 교의 프로그램의 교사들의 만족도에 관한 연구 - 성남시 중고등학교를 대상으로 -
성현경,신선미,고호연,고재언,김효선,최석훈,박정수,Sung, Hyun Kyung,Shin, Seon Mi,Go, Ho-Yeon,Ko, Jae-Un,Kim, Hyo-Sun,Choi, Suk-Hoon,Park, Jeong-Su 대한한방소아과학회 2018 대한한방소아과학회지 Vol.32 No.1
Objectives This study aims to build the baseline data for promoting school health care program by identifying satisfaction level and improvement point through the satisfaction survey after Korean medicine doctor's student health and wellness program in 2016. Methods An association of Korean medicine doctor in Seongnam city conducted Korean medicine doctor's student health and wellness program for 12 middle schools, 6 high schools and 1 special-need school in Seongnam city in 2016. The participating Korean medicine doctor visited each school for 8 times and conducted health consultations, health education classes and Korean medicine treatment for the school students and the school employees. Teachers and administrators from the participating schools answered the self-reported satisfaction questionnaires and the results were analyzed by SPSS 22.0. Results 35 people responded the program satisfaction questionnaires, the overall satisfaction average was $9.40{\pm}0.88$ (out of 10). In the course of the program, satisfaction average regarding the student's health check-ups was $9.05{\pm}0.88$, satisfaction average regarding the informatory brochures for the parents was $9.08{\pm}1.09$, satisfaction average regarding the participation enrollment process was $9.06{\pm}1.16$, and the satisfaction average regarding the questionnaire statistics and the result reports was $8.86{\pm}1.93$. The satisfaction average of the program was as follows: health consultation ($9.20{\pm}1.08$), treatment ($9.31{\pm}0.90$), and health education classes ($8.78{\pm}1.68$). Some of the good things about program were 'Telling students about their physical condition' (57.1%), 'Curing the sick student quickly' (48.6%), 'Providing students with useful information about the health' (48.6%), 'Teaching students how to manage their health and how to manage symptoms' (42.9%). Average satisfaction about sustainability and needs of the program was $9.15{\pm}0.91$, and the participant teachers wanted to learn more about how to manage internet addiction (22.9%), stress (45.7%), atopy (28.6%), neck pain (42.9%), allergic rhinitis (37.1%), and low back pain (34.3%) from the future wellness programs. Conclusions Student health care is one of the most important issue in national health policies. We have designed a bridge model that a local community, school, and doctors can work together to develop. After the implementation of the program, the results of the satisfaction survey showed a very high satisfaction level. This study can be the basis for further improvement of the bridge program as well as the expansion of the program in other settings.