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고민철,정지윤,황성규,유명훈 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.7
Cholesterol granulomas of the temporal bone can occur in the petrous apex, middle ear, andmastoid cavity. Although cholesterol granulomas in the petrous apex often extend to the middlecranial fossa, cholesterol granulomas in the middle ear and mastoids rarely invade the cranialcavity with bony erosion. We report a case of a large cholesterol granuloma involving the posteriorcranial fossa with pneumatic mastoid and not affecting the middle ear. The patient had no otologicor neurologic symptoms, and the mass was found incidentally on a brain MRI included in aregular medical checkup. The mass was removed via a combined transmastoid and suboccipitalapproach without complications, and characteristic pathology findings demonstrated a cholesterolgranuloma.
고민철,박준범,장윤지,고영경 대한치주과학회 2013 Journal of Periodontal & Implant Science Vol.43 No.6
Purpose: This in vitro study was performed to assess the adherence of Porphyromonas gingivalis to a resorbable blast media(RBM) titanium surface pretreated with an ultrasonic scaler or toothbrush and to evaluate the effects of the treatment of theRBM titanium discs on the bacterial removal efficiency of brushing by crystal violet assay and scanning electron microscopy. Methods: RBM titanium discs were pretreated with one of several ultrasonic scaler tips or cleaned with a toothbrush. Thenthe titanium discs were incubated with P. gingivalis and the quantity of adherent bacteria was compared. The disc surfaces incubatedwith bacteria were brushed with a toothbrush with dentifrice. Bacteria remaining on the disc surfaces were quantified. Results: A change in morphology of the surface of the RBM titanium discs after different treatments was noted. There wereno significant differences in the adherence of bacteria on the pretreated discs according to the treatment modality. Pretreatmentwith various instruments did not produce significant differences in the bacterial removal efficiency of brushing withdentifrice. Conclusions: Within the limits of this study, various types of mechanical instrumentation were shown to cause mechanicalchanges on the RBM titanium surface but did not show a significant influence on the adherence of bacteria and removal efficiencyof brushing.
편도 수술 후 식이제한과 자유식이의 수술 후 출혈에 미치는 영향 비교
고민철,허성재,김정수,조형준 대한이비인후과학회 2022 대한이비인후과학회지 두경부외과학 Vol.65 No.8
Background and Objectives There have been several studies on the factors affecting posttonsillectomybleeding; however, investigations on the relationship between postoperativebleeding and diet are insufficient. Different countries have different types of food, and whilethere have been studies on the effects of diet in other countries, no such studies have been reportedin Korea. Therefore, we aimed to investigate the relationship between Korean diet andpostoperative bleeding after tonsillectomy. Subjects and Method To compare the postoperative bleeding outcomes, patients who underwenttonsillectomy by a single surgeon between January 2017 and 2020 were divided intothose who had a diet restriction after surgery and those who had a free diet. Postoperativebleeding outcomes were divided according to the degree of intervention for hemostasis andcompared. Results The study included 115 and 124 patients in the diet-restricted group and free-dietgroup, respectively. There were no statistical differences between the two groups in terms ofgender, age, presence of snoring and frequent tonsillitis, and surgical method. Bleeding occurredin four patients in the diet-restricted group and three patients in the free-diet group. There was no statistical difference between the two groups in the frequency and severity ofpostoperative bleeding. Conclusion Since dietary restriction after tonsillectomy was not helpful to prevent postoperativebleeding, a free and sufficient diet after surgery may prove to be better.
고민철,허성재,김정수 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.2
Angiomyolipoma is a benign tumor that is composed of adipose tissue, blood vessels and smooth muscle. The kidney is the most common site for this tumor. Although extrarenal angiomyolipoma is rarely found in areas other than the kidney, it has been observed in other organs such as liver, heart, mediastinum, spermatic cord, vaginal wall, oral cavity, and so on. Angiomyolipoma in the nasal cavity especially, has been very rarely reported in literature. Furthermore, nasal angiomyolipoma is mostly found in middle aged or old men. In this case, angiomyolipoma was found in a 29-year-old male patient who was the youngest of the reported cases. He complained of nasal obstruction and physical examination revealed a 1.5 cm sized mass in the left posterior part of the nasal septum. The mass was composed of an intimate mixture of mature fat, smooth muscle cells, and thick walled varying sized blood vessels histopathologically coinciding with angiomyolipoma. It was removed via endoscopic surgery without complications
플로팅 건축 폰툰 형식과 상부 시설의 상관성에 관한 연구 : 유럽 사례를 중심으로
고민철,송석기 한국항해항만학회 2011 한국항해항만학회 학술대회논문집 Vol.2011 No.추계
국내의 플로팅 건축 사례의 경우 철근콘크리트 보다는 바지선과 같은 형식의 폰툰이 주로 사용되고 있다. 반면 유럽의 경우 철근콘크리트 폰툰의 사례가 많고 상대적으로 많은 장점을 갖고 있는 것으로 알려져 있다. 유럽 사례를 통해 철근콘크리트 폰툰의 유형을 구분하고 상부시설과의 상관성을 분석함으로써 플로팅 건축 계획에서 계획방법론으로서 활용 가능성을 검토 한다.
고과당식이 랫드모델에서 적하수오 투여에 의한 대사증후군 개선효과
고민철 ( Min Chul Kho ),이윤정 ( Yun Jung Lee ),윤정주 ( Jung Joo Yoon ),이호섭 ( Ho Sub Lee ),강대길 ( Dae Gill Kang ) 대한본초학회 2015 大韓本草學會誌 Vol.30 No.2
Objectives : Polygoni Multiflori Radix (Jeokhasuo in Korean) is a Oriental traditional herbs widely used in East Asian countries. Overconsumption of fructose results in hypertension, dyslipidemia, obesity and impaired glucose tolerance which have documented as a risk of cardiovascular diseases. This experimental study was designed to investigate the beneficial effects of an ethanol extract from Polygoni Multiflori Radix (PMR) in high-fructose (HF) diet-induced metabolic syndrome rat model. Methods : Sprague-Dawley (SD) rats were divided into three groups; Control group, receiving regular diet and tap water, HF group, and HF + PMR group both receiving supplemented with 65% fructose (n=10), respectively. The HF + PMR group initially received HF diet with PMR (100 mg/kg/day) for 8 weeks. Results : PMR significantly prevented the metabolic disturbances such as hyperlipidemia, hypertension and impaired glucose tolerance. Chronic treatment with PMR significantly decreased body weight, fat weight and adipocyte size, suggesting a role of anti-obesity effect. PMR led to improve the hyperlipidemia through the increase in HDL cholesterol level as well as the decrease in triglyceride and LDL cholesterol level. In addition, PMR suppressed adhesion molecules and endothelin-1 (ET-1) expression in aorta resulting in the decrease of hypertension. In muscle tissue, PMR significantly recovered the HF-induced insulin resistance through increase of insulin receptor substrate-1 (IRS-1), p-AMPKα1/2, and p-Akt expression. PMR improved HF-induced metabolic disorders and its action was caused by energy metabolism-mediated insulin signaling activation. Conclusions : These results demonstrate that PMR may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, insulin resistance and hypertension.
고민철(Min-Chul Ko),송석기(Seog-Ki Song) 한국항해항만학회 2012 한국항해항만학회지 Vol.36 No.3
최근의 몇몇 사례를 통해 국내에서도 플로팅 건축물의 확산 가능성에 대한 논의가 시작되고 있으나 국내에서는 아직 플로팅 건축 계획과 관련되어 참고할 만한 가이드라인이나 규정이 제정된 바가 없다. 이 연구는 플로팅 건축물 상부시설에 대한 계획 지침을 구성하는 것을 목표로 하였다. 기존 국내외 지침 중 플로팅 건축물 상부시설 계획에 참조가 될 수 있는 지침을 선택하고 관련 구성 항목 및 구성 체계에 대하여 분석하였다. 이를 통해 이 연구와 직접적으로 연관된 지침 구성 항목을 추출할 수 있었다. 이렇게 추출된 항목을 유사한 내용을 중심으로 분류하여 몇 가지의 범주로 구분하고 각각의 내용을 비교 분석하였다. 이상과 같이 분석된 지침 구성 항목과 체계, 그 내용을 토대로 플로팅 건축물 상부시설에 대한 계획 지침 구성 체계를 제안하였고, 구성 항목 및 주된 규정 내용을 검토하였다. Recently constructed several floating buildings, in Korea, provoked the discussion about the activation of floating architecture. But, there is no guideline for the planning of floating architecture in Korea. This study aims to propose the framework of planning guidelines for the superstructure of floating architecture. For the purpose, collected various exiting guidelines related to floating architecture, and then analysed the structure and components of those guidelines. As a result of analysis, many components, could be used as references, are extracted. After the classification of the components into several categories, then, compared the content of components, derived from different guidelines, in same category. Based on the former analysis and comparison, proposed the framework of planning guidelines for the superstructure of floating architecture, consist of various set of components.