방사선조사가 백서 이하선의 선세포에 미치는 영향에 관한 전자현미경적 연구

고광준,이상래,Ko Kwang Jun,Lee Sang Rae 대한영상치의학회 1988 Imaging Science in Dentistry Vol.18 No.1

The author studied the histopathologic changes according to a single or a split dose and the time after irradiation on the acinar cells of rat parotid gland. 99 Sprague Dawley rats, weighing about l20gm, were divided into control and 3 experimental groups. In experimental groups, GroupⅠ and Ⅱ were delivered a single dose of l5Gy, 18Gy and Group Ⅲ and Ⅳ were delivered two equal split doses of 9Gy, 10.5Gy for a 4 hours interval, respectively. The experimental groups were delivered by a cobalt-60 teletherapy unit with a dose rate of 222cGy/min, source-skin distance of 50㎝, depth of l㎝ and a field size of l2×5㎝. The animals were sacrificed at 1, 2, 3, 6, 12 hours, 1, 3, 7 days after irradiation and examined by light and electron microscopy. The results were as follows: 1. As the radiation dose increased and the acinar cells delivered a single dose exposure were more damaged, and the change of acinar cells appeared faster than those of a split dose exposure. 2. The histopathologic change of acinar cells appeared at 1 hour after irradiation. The recovery from damaged acinar cells appeared at 1 day after irradiation and there was a tendency that the recovery from damage of a split dose exposure was somewhat later than that of a single dose exposure. 3. Light microscope showed atrophic change of acinar cells and nucleus, degeneration and vesicle formation of cytoplasm, widening of intercellular space and interlobular space. 4. Electron microscope showed loss of nuclear membrane, degeneration of nucleus and nucleoli, clumping of cytoplasm, widening and degeneration of rough endoplasmic reticulum, loss of cristae of mitochondria, lysosome, autophagosome and lipid droplet. 5. Electron microscopically, the change of rough endoplasmic reticulum was the most prominent and this appeared at 1 hour after irradiation as early changes of acinar cells. The nuclear change appeared at 2 hours after irradiation and the loss of cristae of mitochondria was observed at 2 hours after irradiation in all experimental groups.

기능성 스포츠 압박의류 착용이 운동수행능력, 무릎 등속성 근력 및 체온 변화에 미치는 영향

고광준 ( Ko Kwang-jun ),박시내 ( Park Si-nae ) 한국체육대학교 체육과학연구소 2017 스포츠사이언스 Vol.35 No.1

본 연구는 기능성 스포츠 압박의류 착용이 운동수행능력, 무릎 등속성 근력 및 운동 체온 변화에 어떠한 차이가 있는지를 확인하는데 그 목적이 있다. 연구대상자는 일반 성인 20명을 대상으로 하였다. 모든 피험자는 기능성 스포츠 압박의류인 타이즈 착용전 적외선 체열 검사와 운동수행능력을 알아보기 위해 악력, 민첩성(사이드스텝), 순발력(제자리높이뛰기) 및 무릎 등속성 근력(60 deg/sec) 검사를 순차적으로 수행하였다. 기능성 스포츠 압박의류 착용 60분 후 다시 적외선 체열 검사, 운동수행능력 검사 및 무릎 등속성 근력(60 deg/sec) 검사를 수행하였다. 이에 대한 연구결과는 다음과 같다. 첫째, 기능성 스포츠 압박의류 착용 후 근력(좌, 우 악력), 파워(서전트 점프), 민첩성(사이드 스텝)은 유의하게 증가하였다. 둘째, 기능성 스포츠 압박의류 착용 후 무릎 등속성기능 검사에서 우측 신근(BW%), 좌측 신근(BW%), 우측 굴근(BW%), 좌측 굴근(BW%)은 유의하게 증가하였다. 하지만 우좌 신근비(%), 우좌 굴근비(%), 우 신굴근비(%), 좌 신굴근비(%)에서는 유의한 차이가 나타나지 않았다. 셋째, 기능성 스포츠 압박의류 착용 후 적외선 체열 검사에서 전면대퇴(우), 전면대퇴(좌), 후면대퇴(우), 후면대퇴(좌), 전면하퇴(우), 전면하퇴(좌), 후면하퇴(우), 후면하퇴(좌)의 체온은 유의하게 감소하는 것으로 나타났다. 결론적으로 기능성 스포츠 압박의류 착용은 운동수행능력 향상, 무릎 근기능 증진이외에도 체온을 낮춰주는 역할을 통해 열 스트레스를 최소화하는 데 효과적으로 작용한다고 생각된다. The purpose of this study was to determine the difference in exercise performance, knee isokinetics strength and body temperature change of functional compression sports wear. The study subjects were 20 general adults. All subjects underwent sequential tests of grip strength, agility (side step), power (sargent jump) and isokinetic muscle joint (60 deg/sec) in order to examine the infrared thermography and exercise performance before wearing the functional compression sports wear. After 60 minutes of functional compression sports wear, the subjects performed the infrared thermography, exercise performance test and isokinetics test(60 deg / sec. The results of this study are as follows. First, muscle strength (left and right grip strength), power (sargent jump), and agility (side step) increased significantly after wearing functional pressure sports wear. Second, in the knee isokinetics test, the right extensor muscle(BW%), left extensor muscle (BW%), right flexor muscle (BW%), and left flexor muscle (BW%) were significantly increased after functional compression sports wear. However, there was no significant difference between the right and left extensor muscles ratio(%), right and left flexor muscles ratio (%), right extensor and flexor muscle ratio (%), left extensor and flexor muscle ratio (%). Third, after the functional compression sports wear, the infrared thermogram showed that the Anterior thigh (right), Anterior thigh (left), Posterior thigh (right), Posterior thigh (left), Anterior lower limb (right), Anterior lower limb (left) Body temperature was significantly decreased. In conclusion, it is thought that functional compression sports wear apparel is effective in minimizing heat stress by improving exercise performance, lowering knee muscular function, and lowering body temperature.

장기적인 흡연이 젊은 성인남성의 유산소 운동능력에 미치는 영향

선상규 ( Sang Kyu Sun ),정동춘 ( Dong Chun Jung ),고광준 ( Kwang Jun Ko ) 한국스포츠정책과학원(구 한국스포츠개발원) 2006 체육과학연구 Vol.17 No.2

본 연구는 장기간 흡연이 젊은 성인 남성의 유산소 운동능력에 영향을 미치는 가를 알아보기 위해서 시행하였다. 연구의 대상자는 2005년 1월에서 12월까지 N센터에서 건강검진을 시행한 건강한 20대 성인 남성 199명으로 비흡연군 93명과 흡연군 106명(하루 평균 19.8±6.9개피, 흡연기간 7.7±2.7년)으로 구분하여 신체구성, 혈압, 폐기능, 최대산소섭취량, 운동중 최대심박수, 운동지속시간 등을 측정하였으며 그 결과는 다음과 같다. 첫째, 신체구성{체질량지수(BMI), 복부지방율(WHR), 체지방률(%fat)}, 안정시 혈압 및 심박수, 폐기능(FVC, FEV1.0) 집단간 유의한 차이는 없었다. 둘째, 최대산소섭취량, 운동중 최대심박수, 운동지속시간은 비흡연군이 흡연군보다 각각 높게 나타났다(p<0.05). 그러나 무산소성 역치는 차이가 없었다. 셋째, 흡연기간이 최대산소섭취량(r=-.160), 운동중 최대심박수(r=-.231), 운동지속시간(r=-.205)에서 유의한 상관관계를 보였으며(p<0.01), 흡연량에서는 최대산소섭취량(r=-.187), 운동중최대심박수(r=-.281), 운동지속시간(r=-.275)에서 유의한 상관관계를 보였다(p<0.05). 그 밖에 측정항목과의 의미있는 상관관계는 확인할 수 없었다. 지속적인 흡연이 20대의 성인 남성의 유산소 운동능력에 영향을 주는 것으로 나타났으며 안정시 심박수 및 혈압에는 영향을 주지 않는 것으로 나타났다. 흡연 이외에도 생활습관, 운동, 음주 등과 같이 다른 복합적인 요소가 신체에 영향을 미칠 수 있기 때문에 지속적인 연구가 진행되어야 할 것으로 사료된다. This study examined the effects of chronic smoking on young male adults` cardiorespiratory function. The examinees were composed of 199 young male adults of 20s who took medical investigation between January and December, 2005 at N Center. They were divided into two groups - smokers(106 people, smoking 19.8±6.9 cigarettes a day for 7.7±2.7 years); non-smokers - and took the measure of their body components, blood pressure, pulmonary capacity, VO2max, HRmax, and exercise duration time. The collected data were analyzed by one-away ANOVA and pearson correlations. The results were as follows. 1. There was no significant difference in Body components(BMI, WHR, %fat), pulmonary capacity(FVC, FEV1.0), rest heart rates and blood pressure(SBP, DBP) between two groups. 2. Maximal oxygen intakes(VO2max), maximal heart rates(HRmax) and exercise duration time of non-smokers were higher than those of smokers. However, there was no critical difference in threshold between two groups. 3. There were significant correlations between smoking duration and VO2max(r=-.160) and HRmax(r=-.231) and exercise duration time(r=-.205)(p<0.01). Also, there were important correlations between the number of cigarettes smokers smoke a day and VO2max(r=-.187), HRmax(r=-.281), and exercise duration time(r=-.275)(p<0.05). However, the results did not show significant correlations between smoking and the other variables. The results suggest that chronic smoking has negative effects on young male adults` cardiorespiratory function, whereas it has no effects on rest heart rate and blood pressure. It is necessary to study the relations between cardiorespiratory and additional behavioral and environmental factors such as smoking, drinking and lifestyle.

대도시와 중소도시의 성인 여성의 체성분 및 체력의 비교

선상규(Sun, Sang-Kyu),정동춘(Jung, Dong-Chun),박미희(Park, Mi-Hee),고광준(Ko, Kwang-Jun),김지숙(Kim ji-Suk),정운식(Jung, Woon-Sik),이강구(Lee, Kang-Koo),이미정(Lee, Mi-Joung),김다혜(Kim, Da-Hye),조승환(Cho, Seung-Hwan) 대한운동학회 2006 아시아 운동학 학술지 Vol.8 No.2

본 연구는 대도시와 중소도시의 성인 여성의 체성분 및 체력의 차이를 알아보기 위하여 실시하였다. 연구방법은 N기관에서 2005년 3월에서 11월까지 시행한 지역순회 검진 자료 중 인구 백만명 이상 대도시의 성인 여성 519명 (30대 : 150명, 40대 : 226명, 50대 : 143명)과 삼십만명 이하 중소도시의 성인 여성 416명(30대 : 197명, 40대 : 131명, 50대 : 88명)을 대상으로 체질량지수, 체지방률, 복부지방률, 심폐지구력, 유연성, 근력, 근지구력, 민첩성, 순발력 등을 측정하여 비교하였다. 그 결과는 다음과 같다. 1)지역간 차이는 체성분(BMI, %Fat, WHR) 심폐지구력, 유연성 , 근력, 순발력은 대도시와 중소도시간의 유의한 차이는 없었다. 그러나 복근지구력, 상지근지구력, 민첩성은 대도시가 중소도시보다 높게 나타났다. 2)연령별 차이는 체성분(BMI, %Fat, WHR)은 연령대가 증가하면서 증가하는 것으로 나타났으며, 심폐지구력, 근력, 상지근지구력, 복근지구력, 민첩성, 순발력 등은 연령대의 증가에 따라 유의하게 감소하였다. 그러나, 유연성은 연령에 변화에 따른 유의한 차이는 없었다. This study examined the comparisons of body composition and physical fitness between people who live in the city, over 1 million in population, and people in under 300,000 in population. They were two groups - Metropolitan(519 people, 30 s : 150 people, 40 s : 226people, 50 s : 143people); Small city(416 people 30 s : 197 people 40 s : 131 people 50 s : 88 people) - and took the measure of their body components, Cardiorespiratory endurance, Abdominal endurance, Upper-body endurance, Strength, Flexibility, Agility, Power. The collected data were analyzed by two-way ANOVA. The results were as follows. 1)The town shows no significant difference in BMI, WHR, %fat, Cardiorespiratory endurance, Strength, flexibility, Power among the two groups. However, Metropolitan showed higher Abdominal endurance, Upper-body endurance, Agility than the small city. 2)The results also showed that BMI, %Fat, WHR were incrementing, and cardiorespiratory endurance, Abdominal endurance, Upper-body endurance, Strength, Agility, Power significantly decrementing among older people. However, flexibility did not show any difference.

기준점 수와 분포에 따른 좌표변환 특성 분석

곽성남(kwak Seong Nam),조정관(Cho Jung Gwan),고광준(Ko Kwang Jun),장문현(Jang Mun Hyun) 한국지적정보학회 2005 한국지적정보학회지 Vol.7 No.1

본 연구는 GPS성과를 현행성과로 변환할 때 필요로 하는 변환계수 산정을 위해 변환에 이용되는 기준점의 개수와 배치형태에 따른 변환계수의 특성을 비교ㆍ분석하여 GPS측량을 위한 관측망의 계획에 있어 변환에 이용할 기준망을 효과적으로 구성하는 방법을 제시하였다. This study compares and analyzes the characteristics of transformation coefficients according to the number and arrangement of control points used to conversion for calculation of transformation coefficients needed for changing GPS results into current ones and suggests how to structure basic network used for conversion in planning observatory network of GPS surveying.

성인남녀의 연령대별 등속성 무릎 근력 평가 기준치 설정에 관한 연구

선상규 ( Sun Sang-kyu ),정동춘 ( Jung Dong-chun ),이강구 ( Lee Kang-koo ),이미정 ( Lee Mi-joung ),김일석 ( Kim Il-suk ),송영규 ( Song Young-kyu ),고광준 ( Ko Kwang-jun ),김동영 ( Kim Dong-young ) 대한운동사협회 2006 대한운동사협회 운동사대회자료집 Vol.2006 No.-

An objective of this research was to investigate the average value in a men and women on muscle strength of knee extensor and flexor by using biodex system3 isokinetic dynamometer to different ages. Out of 2908 people, this research paper was to find out the difference of the peak torque in relation to the body weight between the age and sex. And also the deficit of peak torque between the right and left of the body to the opposing muscle's peak torque ratio. The obtained results are as it follows: 1. peak torque to body weight in 20~60‘s men, case of right flexor average value appeared with 126.3, 134.6, 133.1, 117.4, 90.6, case of left flexor average value appeared with 125.0, 139.0, 139.1, 124.0, 91.4. It continued case of right extensor average value appeared with 267.4, 270.0, 253.0, 227.4, 186.7, case of left extensor average value appeared with 265.2, 271.8, 253.7, 227.5, 185.1 2. peak torque to body weight in 20~60‘s women, case of right flexor average value appeared with 83.5, 82.8, 78.3, 71.6, 63.9, case of left flexor average value appeared with 83.2, 83.8, 78.1, 71.2, 62.0. It continued case of right extensor average value appeared with 191.0, 179.3, 163.0, 147.8, 129.8, case of left extensor average value appeared with 190.1, 179.2, 164.6, 148.6, 127.9. 3. Deficit of peak torque between right and left in 20~60‘s men, case of right extensor average value appeared with 8.1, 7.3, 8.0, 9.1, 11.3, case of left extensor average value appeared with 11.5, 9.5, 9.6, 11.2, 14.1. 4. Deficit of peak torque between right and left in 20~60‘s women, case of right extensor average value appeared with 9.3, 8.1, 8.7, 11.3, 11.5, case of left extensor average value appeared with 12.9, 11.9, 12.7, 13.6, 14.1. 5. An opposing muscle(flexor/extensor) peak torque ratio in 20~60‘s men, case of average value appeared with 47.1/47.2, 51.5/50.2, 55.3/53.0, 55.4/52.4, 49.9/49.3. 6. An opposing muscle(flexor/extensor) peak torque ratio in 20~60‘s women, case of average value appeared with 44.0/44.0, 47.1/46.5, 47.7/48.4, 48.3/48.9, 48.9/49.8.

악관절 기능장애 환자의 하악과두 위치에 관한 단층 및 두부방사선 계측학적 연구

김민숙,고광준 大韓口腔顎顔面 放射線學會 1990 Imaging Science in Dentistry Vol.20 No.2

The author analysed tomographic and cephalometric radiographs of 82 temporomandibular joints from 41 symptomatic patients and 40 temporomandibular joints from 20 asymptomatic young adults. The results were as follows; 1. The mean condylar angulation in control group and patient group was 21.72± 6.48°20.13±9.14°respectively and there was no significant difference between two groups. 2. the mean depth of cut was 6.63±0.38cm in control group and 6.57±0.46cm in patient group. 3. Mean height and width of condylar head were 6.66±1.83mm, 12.42±0.49mm in control group and 6.22±1.36mm, 11.93±1.92mm in patient group. 4. The mean height of articular fossa was 10.20±2.04mm in control group and 9.89±1.98mm in patient group. The mean width of articular fossa was 21.08±2.08mm in control group and 21.24±3.03mm in patient group. 5. In centric occlusion the superior joint space was largest(4.15±0.93mm), followed by the posterior joint space(2.99±0.97mm) and the anterior joint space(2.70±0.73mm) in control group. The superior joint space(3.47±1.31mm) and posterior joint space(3.47±7.07mm) were same in patient group. There was significant difference in left superior joint spaces between two groups(p<0.05). 6. The condylar position in articular fossa was displaced anteroinferiorly(0.99 ±3.65mm anteriorly, 1.75±1.01mm inferiorly) in control group and posteroinferiorly(3.20±4.69mm posteriorly, 1.25±1.87mm inferiorly) in patient group with 1 inch opening. In maximum opening, it was displaced anteroinferiorly(6.09±3.55mm anteriorly, 1.38±2.47mm inferiorly) in control group and anteroinferiorly(1.70±5.96mm anteriorly, 1.37±1.85mm inferiorly) in patient group. There was significant difference in anteroposterior position of both condyles with 1 inch opening and maximum opening between two groups(p<0.01). 7. The mean inclination of upper central incisor and the posterior inclination of articular eminence in control group was 65.60±6.04°, 58.88±9.18°in control group, and 67.14±8.41°, 59.70±9.08°in patient group respectively. There was no significant correlation between two groups.

학생 이질성의 실태 분석

高光俊 圓光大學校大學院 1996 論文集 Vol.15 No.-

The necessity of this study is that the students' individual learning in front line school education, that is, the problem of induvidualization of learning, remains a long-cherished desire internally and externally. So far, a great many people have directed their concern and efforts toward solving this problem. There are IPI(Individually Prescribed Instruction), Glaser's Class Model, Carroll's School Learning Model, Bloom's Mastery Learning Model, which have contributed to the individualization, and also the Education Development Project (EDP) developed within this country. The individualization of learning still remains unsolved internally and externally. However, the settlement for that is being explored multi-laterally. In order for the individual learning to be developed in school education scene, it is important to confirm and analyze accurately and reasonably the heterogeneity of each student, the prerequisite for the realization of individual learning. Despite the difference in each student's disposition, concern, learning ability, and learning speed, if teachers grasp precisely and individually and teach these things, the problem of individualization is expected to be solved. What matters is to analyze and confirm precisely each student's individual learning feature regarding the learning contents of particular time to be learned by students in the development process of regular teaching-learning. It is impossible for a teacher to have each student learn individually in the class consisting of many students under the circumstances where the possibility of these things being solved is slim. In this respect, this study puts focus on confirmation of the realities of students' heterogeneity on the basis of a new conception system which can confirm students' heterogeneity in a well-founded manner. This study established the following basic objects of study on the basis of the necessity of the above-mentioned study. This study has its basic objects in investigating the conceptual authority of systemized students' learning feature in a new scholary respects and analyzing corroboratively how it is conducive to assaying and confirming the heterogeneity realities of students in teaching-learning scene. In order to attain such basic objects of this study, two study contents were selected. First, investigate the conceptual authority of the confirmation of students' heterogeneity in the position of the study of Human Education. Second, analyze and confirm each student's heterogeneity in the following six aspects. A. Learner's Starting Point of Learning B. Learner's Ability of Learning in Terms of Difficulty C. Learner's Time Spent in Learning D. The number of assignments of collective common learning E. the accomplishment degree of collective common learning assignment F. the selection accuracy of proper learning assignment Two methods, the analysis of related documents and the corroborative analysis of statistics management, are used in this study. This study was conducted in the study and practice room of The Human Education Research Institute Corporation. The second unit of the third-grade and the fifth-grade were the analysis subjected among the learning results of the first term course of the 1995 school year developed in one third-grade learning class and the fifth-grade learning class of elementary school. On the basis of the said study results, a conclusion was made as follows. In the teaching-learning process, the individualization of learning starts from teacher's accurate grasp of students' heterogeneity. It is the students' learning feature that is basic to teachers' confirming each student's heterogeneity. The success or failure of the individualization of learning in school education depends on how exactly the teacher confirms diverse learning feature of each student in the development process of teaching-learning. What is confirmed after this study is that the conceptual system established in accordance with the Study of Education and the ESANET-STL (Education Service Automation Network for School Teaching-Learning) developed for it to be practiced should be applied. Accordingly, it is prospected that the individualization of learning in the school education of this country will be realized if teachers apply this ESANET-STL properly and confirm each student's learning feature accurately.

부정교합자의 하악과두 위치에 관한 단층방사선학적 연구

김영주,고광준 大韓口腔顎顔面 放射線學會 1989 Imaging Science in Dentistry Vol.19 No.1

The author analysed tomograms and submento-vertex radiograms of 90 temporomandibular joints from 45 asymptomatic young adults. 15 had Angle class Ⅰmalocclusion, 15 class Ⅱ and 15 class Ⅲ. Corrected lateral tomograms were obtained in three condylar positions; centric occlusion, centric relation and 1 inch mouth opening. The condylar angulation, depth of cut, joint spaces were analysed in each radiogram. The obtained results were as follows; 1. The mean condylar angulation in Angle class Ⅰ,Ⅱ,Ⅲ group was 17.55 ±5.51˚, 13.33 ±8.85˚, 16.25 ±6.60˚, respectively, and there was no significant difference in each group. The mean condylar angulation of right side(16.62 ±7.23˚) was larger than left side(14.80 ±7.33˚). 2. The mean depth of cut in Angle class Ⅰ, Ⅱ, Ⅲ group was 8.13 ±1.61㎝, 3.05 ±3.80㎝, 7.75 ±2.19㎝, respectively. Angle class Ⅰ and class Ⅱ group revealed significant difference in measurement (p<0.01). 3. The mean height of articular fossa in Angle class Ⅰ, Ⅱ, Ⅲ group was 8.67 ±3.06㎜, 9.61 ±2.57㎜, 8.93 ±2.83㎜, respectively. And the mean width of articular fossa was 19.90 ±2.80㎜, 19.48 ±3.83㎜, 20.36 ± 4.82㎜, respectively. 4. The mean height and width of condylar head was 5.11 ±1.16㎜, 11.20 ±2.26㎜, respectively. 5. In centric occlusion, the superior joint space was the largest (3.42 ±1.42㎜), followed by anterior joint space (2.94 ±1.95㎜) and the posterior joint space (2.64 ±1.19㎜). In centric relation, the anterior joint space was largest (3.86 ±2.17㎜), followed by the superior joint space (3.64 ±3.68㎜) and the posterior joint space (1.18 ±0.77㎜). 6. The displaced measurement from centric relation to centric occlusion was 1.10 ±1.04㎜ anteriorly and 0.24 ±0.97㎜ inferiorly. In 1 inch mouth opening state, the condylar head displaced posteroinferiorly (2.49 ±2.49㎜ posteriorly, 1.17 ±1.34㎜ inferiorly) from the apex of articular eminence. And Angle class Ⅰ and Ⅱ group, Angle class Ⅱ and Ⅲ group revealed significant difference in posterior measurement, respectively (p<0.01).

정중 하악 낭종의 증례

고광준 全北大學校 齒醫學硏究所 1987 전북치대논문집 Vol.5 No.1

The median mandibular cyst is an extremely rare lesion of dispute origin that occurs in the midline of the mandible. While some authors believe that it results from proliferation of epithelial remnants entrapped during fusion of the mandibular arches, others suggest that it is a primordial odontogenic cyst that develops from a supernumerary enamel organs. This author experienced a case of median mandibular cyst in 40-year-old man with a complaint of swelling and pus discharge from anterior mandible. Panoramic view revealed well defined elliptical radiolucency extending from lower left 2nd premolar area to right lower 2nd premolar area. And periapical view showed scalloped appearance of superior margin of the lesion. This is a very interesting case that differential diagnosis has to consider traumatic bone cyst or radicular cyst radiographically.