방사선조사가 백서 이하선의 선세포에 미치는 영향에 관한 전자현미경적 연구

고광준,이상래,Ko Kwang Jun,Lee Sang Rae 대한영상치의학회 1988 Imaging Science in Dentistry Vol.18 No.1

The author studied the histopathologic changes according to a single or a split dose and the time after irradiation on the acinar cells of rat parotid gland. 99 Sprague Dawley rats, weighing about l20gm, were divided into control and 3 experimental groups. In experimental groups, GroupⅠ and Ⅱ were delivered a single dose of l5Gy, 18Gy and Group Ⅲ and Ⅳ were delivered two equal split doses of 9Gy, 10.5Gy for a 4 hours interval, respectively. The experimental groups were delivered by a cobalt-60 teletherapy unit with a dose rate of 222cGy/min, source-skin distance of 50㎝, depth of l㎝ and a field size of l2×5㎝. The animals were sacrificed at 1, 2, 3, 6, 12 hours, 1, 3, 7 days after irradiation and examined by light and electron microscopy. The results were as follows: 1. As the radiation dose increased and the acinar cells delivered a single dose exposure were more damaged, and the change of acinar cells appeared faster than those of a split dose exposure. 2. The histopathologic change of acinar cells appeared at 1 hour after irradiation. The recovery from damaged acinar cells appeared at 1 day after irradiation and there was a tendency that the recovery from damage of a split dose exposure was somewhat later than that of a single dose exposure. 3. Light microscope showed atrophic change of acinar cells and nucleus, degeneration and vesicle formation of cytoplasm, widening of intercellular space and interlobular space. 4. Electron microscope showed loss of nuclear membrane, degeneration of nucleus and nucleoli, clumping of cytoplasm, widening and degeneration of rough endoplasmic reticulum, loss of cristae of mitochondria, lysosome, autophagosome and lipid droplet. 5. Electron microscopically, the change of rough endoplasmic reticulum was the most prominent and this appeared at 1 hour after irradiation as early changes of acinar cells. The nuclear change appeared at 2 hours after irradiation and the loss of cristae of mitochondria was observed at 2 hours after irradiation in all experimental groups.

빛의 부족으로 불편함을 겪는 사람들을 위한 조명 디자인 연구

고광준(Ko, Kwang-June),윤지수(Yoon, Ji-Soo),은나래(Eun, Na-rea),이동연(Lee, Dong-Yeon) 한국디자인학회 2012 한국디자인학회 학술발표대회 논문집 Vol.2012 No.10

하악골에 발생한 골화성섬유종의 증례

고광준(Ko Kwang Joon) 대한치과의사협회 1986 대한치과의사협회지 Vol.24 No.5

기능성 스포츠 압박의류 착용이 운동수행능력, 무릎 등속성 근력 및 체온 변화에 미치는 영향

고광준 ( Ko Kwang-jun ),박시내 ( Park Si-nae ) 한국체육대학교 체육과학연구소 2017 스포츠사이언스 Vol.35 No.1

본 연구는 기능성 스포츠 압박의류 착용이 운동수행능력, 무릎 등속성 근력 및 운동 체온 변화에 어떠한 차이가 있는지를 확인하는데 그 목적이 있다. 연구대상자는 일반 성인 20명을 대상으로 하였다. 모든 피험자는 기능성 스포츠 압박의류인 타이즈 착용전 적외선 체열 검사와 운동수행능력을 알아보기 위해 악력, 민첩성(사이드스텝), 순발력(제자리높이뛰기) 및 무릎 등속성 근력(60 deg/sec) 검사를 순차적으로 수행하였다. 기능성 스포츠 압박의류 착용 60분 후 다시 적외선 체열 검사, 운동수행능력 검사 및 무릎 등속성 근력(60 deg/sec) 검사를 수행하였다. 이에 대한 연구결과는 다음과 같다. 첫째, 기능성 스포츠 압박의류 착용 후 근력(좌, 우 악력), 파워(서전트 점프), 민첩성(사이드 스텝)은 유의하게 증가하였다. 둘째, 기능성 스포츠 압박의류 착용 후 무릎 등속성기능 검사에서 우측 신근(BW%), 좌측 신근(BW%), 우측 굴근(BW%), 좌측 굴근(BW%)은 유의하게 증가하였다. 하지만 우좌 신근비(%), 우좌 굴근비(%), 우 신굴근비(%), 좌 신굴근비(%)에서는 유의한 차이가 나타나지 않았다. 셋째, 기능성 스포츠 압박의류 착용 후 적외선 체열 검사에서 전면대퇴(우), 전면대퇴(좌), 후면대퇴(우), 후면대퇴(좌), 전면하퇴(우), 전면하퇴(좌), 후면하퇴(우), 후면하퇴(좌)의 체온은 유의하게 감소하는 것으로 나타났다. 결론적으로 기능성 스포츠 압박의류 착용은 운동수행능력 향상, 무릎 근기능 증진이외에도 체온을 낮춰주는 역할을 통해 열 스트레스를 최소화하는 데 효과적으로 작용한다고 생각된다. The purpose of this study was to determine the difference in exercise performance, knee isokinetics strength and body temperature change of functional compression sports wear. The study subjects were 20 general adults. All subjects underwent sequential tests of grip strength, agility (side step), power (sargent jump) and isokinetic muscle joint (60 deg/sec) in order to examine the infrared thermography and exercise performance before wearing the functional compression sports wear. After 60 minutes of functional compression sports wear, the subjects performed the infrared thermography, exercise performance test and isokinetics test(60 deg / sec. The results of this study are as follows. First, muscle strength (left and right grip strength), power (sargent jump), and agility (side step) increased significantly after wearing functional pressure sports wear. Second, in the knee isokinetics test, the right extensor muscle(BW%), left extensor muscle (BW%), right flexor muscle (BW%), and left flexor muscle (BW%) were significantly increased after functional compression sports wear. However, there was no significant difference between the right and left extensor muscles ratio(%), right and left flexor muscles ratio (%), right extensor and flexor muscle ratio (%), left extensor and flexor muscle ratio (%). Third, after the functional compression sports wear, the infrared thermogram showed that the Anterior thigh (right), Anterior thigh (left), Posterior thigh (right), Posterior thigh (left), Anterior lower limb (right), Anterior lower limb (left) Body temperature was significantly decreased. In conclusion, it is thought that functional compression sports wear apparel is effective in minimizing heat stress by improving exercise performance, lowering knee muscular function, and lowering body temperature.

4개의 전자기 코일을 이용한 위치기반의 전자기장 제어에 관한 연구

고광준(Gwangjun Go),최현철(Hyunchul Choi),이청(Cheong Lee),고성영(Seong Young Ko),박종오(Jong-Oh Park),박석호(Sukho Park) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.11

Recently, various wireless manipulating methods for microrobots have been proposed. Among these methods, an electromagnetic actuation (EMA) method showed free motion and accurate controllability of wireless microrobots. In previous our study, eight electromagnetic coils (two stationary pairs of Helmholtz coil and two stationary pairs of Maxwell coil) were used for 2-DOF (Degree Of Freedom). In contrast, this paper proposed a new EMA system with only four electromagnetic coils, which can realize 2-DOF (translation and roll motion). Generally, for the control of many EMA systems, it was assumed that the electromagnetic field in workspace is identical. However, the electromagnetic field was distorted in boundary of the workspace owing to the characteristic of the electromagnetic field. To improve the locomotive accuracy of the microrobot, the position based magnetic field control method for the microrobot was developed. Finally, through the position based magnetic field control method in the proposed EMA system, the microrobot can be accurately moved along the desired path.

Enhancement of Electromagnetic Actuation System (EMAs) for Helical Micro-robot Motion using Resonance Effect

Kim Tien Nguyen,G. J. Ko(고광준),J. O. Park(박종오),S. H. Park(박석호) 한국정밀공학회 2016 한국정밀공학회 학술발표대회 논문집 Vol.2016 No.10월

장기적인 흡연이 젊은 성인남성의 유산소 운동능력에 미치는 영향

선상규 ( Sang Kyu Sun ),정동춘 ( Dong Chun Jung ),고광준 ( Kwang Jun Ko ) 한국스포츠정책과학원(구 한국스포츠개발원) 2006 체육과학연구 Vol.17 No.2

본 연구는 장기간 흡연이 젊은 성인 남성의 유산소 운동능력에 영향을 미치는 가를 알아보기 위해서 시행하였다. 연구의 대상자는 2005년 1월에서 12월까지 N센터에서 건강검진을 시행한 건강한 20대 성인 남성 199명으로 비흡연군 93명과 흡연군 106명(하루 평균 19.8±6.9개피, 흡연기간 7.7±2.7년)으로 구분하여 신체구성, 혈압, 폐기능, 최대산소섭취량, 운동중 최대심박수, 운동지속시간 등을 측정하였으며 그 결과는 다음과 같다. 첫째, 신체구성{체질량지수(BMI), 복부지방율(WHR), 체지방률(%fat)}, 안정시 혈압 및 심박수, 폐기능(FVC, FEV1.0) 집단간 유의한 차이는 없었다. 둘째, 최대산소섭취량, 운동중 최대심박수, 운동지속시간은 비흡연군이 흡연군보다 각각 높게 나타났다(p<0.05). 그러나 무산소성 역치는 차이가 없었다. 셋째, 흡연기간이 최대산소섭취량(r=-.160), 운동중 최대심박수(r=-.231), 운동지속시간(r=-.205)에서 유의한 상관관계를 보였으며(p<0.01), 흡연량에서는 최대산소섭취량(r=-.187), 운동중최대심박수(r=-.281), 운동지속시간(r=-.275)에서 유의한 상관관계를 보였다(p<0.05). 그 밖에 측정항목과의 의미있는 상관관계는 확인할 수 없었다. 지속적인 흡연이 20대의 성인 남성의 유산소 운동능력에 영향을 주는 것으로 나타났으며 안정시 심박수 및 혈압에는 영향을 주지 않는 것으로 나타났다. 흡연 이외에도 생활습관, 운동, 음주 등과 같이 다른 복합적인 요소가 신체에 영향을 미칠 수 있기 때문에 지속적인 연구가 진행되어야 할 것으로 사료된다. This study examined the effects of chronic smoking on young male adults` cardiorespiratory function. The examinees were composed of 199 young male adults of 20s who took medical investigation between January and December, 2005 at N Center. They were divided into two groups - smokers(106 people, smoking 19.8±6.9 cigarettes a day for 7.7±2.7 years); non-smokers - and took the measure of their body components, blood pressure, pulmonary capacity, VO2max, HRmax, and exercise duration time. The collected data were analyzed by one-away ANOVA and pearson correlations. The results were as follows. 1. There was no significant difference in Body components(BMI, WHR, %fat), pulmonary capacity(FVC, FEV1.0), rest heart rates and blood pressure(SBP, DBP) between two groups. 2. Maximal oxygen intakes(VO2max), maximal heart rates(HRmax) and exercise duration time of non-smokers were higher than those of smokers. However, there was no critical difference in threshold between two groups. 3. There were significant correlations between smoking duration and VO2max(r=-.160) and HRmax(r=-.231) and exercise duration time(r=-.205)(p<0.01). Also, there were important correlations between the number of cigarettes smokers smoke a day and VO2max(r=-.187), HRmax(r=-.281), and exercise duration time(r=-.275)(p<0.05). However, the results did not show significant correlations between smoking and the other variables. The results suggest that chronic smoking has negative effects on young male adults` cardiorespiratory function, whereas it has no effects on rest heart rate and blood pressure. It is necessary to study the relations between cardiorespiratory and additional behavioral and environmental factors such as smoking, drinking and lifestyle.

GPS/Leveling에 의한 표고결정 연구

조정관(Cho Jung Gwan),곽성남(Kwak Seong Nam),고광준(Ko Gwang Jun),송인호(Song In Ho) 한국지적정보학회 2005 한국지적정보학회지 Vol.7 No.2

본 연구는 지역적인 지오이드고를 구하여 소구점의 표고와 부합여부를 확인하는데 목적이 있으며, 방법은 삼각점표고 성과가 아닌 정밀한 1등 수준점과 2등 수준점을 이용하여 직접 GPS관측, WGS84좌표계의 타원체고를 구하고 정표고와 차이점을 평균하여 여러 가지 유형으로 소구점의 표고를 비교ㆍ분석하였다. 연구결과 소구점의 표고 수준점은 양호하게 나타났으나, 지적삼각점 표고는 삼각점에서 연직각관측에 의한 간접수준측량 방식을 사용했으므로 정밀도는 높지만 그 값의 차이만큼 균일하게 벗어남을 알 수 있었고, 소구점의 표고를 비교ㆍ분석한 결과 표고의 차이가 크게 영향을 미치지 않으므로 GPS 관측의 표고산정 값을 이용하여 현실적인 표고 값을 구하는 것이 효과적인 것으로 나타났다. This study aims at ascertaining the coincidence with geoidal height and height of observed point. and the way of confirmation was to compare and make an analysis the elevation of observed point with many types after averaging the orthometric and the difference. The way, we've sought for ellipsoid height of WGS84 coordinate system, was not the result of triangulation point elevation but the survey of GPS with the closer first order bench mark and second order bench mark. Studies showed that the elevation bench mark of observed point was nice, The cadastral triangulation point which was surveyed in indirect leveling by the measurement of vertical angle at the triangulation point was precision, however, we could realize it had error uniformly. The result of comparing and analysis with the elevation of observed point showed that calculating the realistic elevation with the elevation result of GPS observation, because of the difference of the height did not affect very much.

관형소화기관 진단을 위한 전자기 구동 캡슐내시경의 3차원 나선형 운동

이청(Cheong Lee),최현철(Hyunchul Choi),정세미(Semi Jeong),고광준(Gwangjun Go),고성영(Seong Young Ko),박종오(Jong-Oh Park),박석호(Sukho Park) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.11

We propose a new electromagnetic actuation system for capsule endoscope with steering, locomotion and rotational motion. The proposed electromagnetic actuation system consists of 3 pair of Helmholtz oils and 1 pair of Maxwell coils. The precessional motion and ascending motion of the magnetic capsule endoscope were realized using the proposed electromagnet actuation system. In addition, the magnetic capsule endoscope can move in an esophagus by the propulsion and the rotation with centrifugal force. First, we fabricated a capsule endoscope prototype with a desired magnetization direction and verified its scanning function through the helical motion of the capsule endoscope prototype in the mock-up of tubular digestive organs. Second, the capsule endoscope prototype also has a propulsion force to the perpendicular direction of axial vector when it tracks the helical path, and this force makes the capsule endoscope prototype to attach the inner wall of tubular environment. Through various experiments, the precession of the magnetic capsule endoscope using a glass tube was demonstrated and the feasibility of the capsule endoscope actuated by the electromagnetic actuation system was verified.

기준점 수와 분포에 따른 좌표변환 특성 분석

곽성남(kwak Seong Nam),조정관(Cho Jung Gwan),고광준(Ko Kwang Jun),장문현(Jang Mun Hyun) 한국지적정보학회 2005 한국지적정보학회지 Vol.7 No.1

본 연구는 GPS성과를 현행성과로 변환할 때 필요로 하는 변환계수 산정을 위해 변환에 이용되는 기준점의 개수와 배치형태에 따른 변환계수의 특성을 비교ㆍ분석하여 GPS측량을 위한 관측망의 계획에 있어 변환에 이용할 기준망을 효과적으로 구성하는 방법을 제시하였다. This study compares and analyzes the characteristics of transformation coefficients according to the number and arrangement of control points used to conversion for calculation of transformation coefficients needed for changing GPS results into current ones and suggests how to structure basic network used for conversion in planning observatory network of GPS surveying.