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일본동양의학회지에 수록된 ‘부작용’에 관한 논문 분석 : 한약 단독 투여시의 부작용
강휘중(Hwi-Joong Kang),김효동(Hyo-Dong Kim),박호재(Ho-Jae Park),이부균(Boo-Kyun Lee),박성하(Seong-Ha Park),이장천(Jang-Cheon Lee) 한국한의학연구원 2011 한국한의학연구원논문집 Vol.17 No.2
Objective : This study reviews the articles about ‘Side effect’ published in the Japanese Journal of Oriental Medicine to better understand about side effects of herbal medication and to encourage clinicians, the authorities and the public to establish side effects reporting system. Method : We searched articles published in the Japanese Journal of Oriental Medicine by using keyword ‘副作用(Side effect)’ in the CiNii. Results : Among the 118 articles collected, 14 are clinical articles about side effect of prescriptions, 13 are reports about side effect of prescriptions presented from Japanese Ministry of Health, Labour and Welfare, 36 are clinical articles about relief of side effects derived from taking western medicine by taking a herbal prescription, 8 are studies about the effect of a herbal prescription combined with western medicine or comparative studies between a herbal prescription and western medicine, and so on. Conclusions : Lots of articles deal with side effects of Aconiti Lateralis Radix Preparata, Bupleuri Radix and so on. When side effects occurred, removing a certain herbal drug or quitting a herbal prescription is helpful to relieve or disappear the side effects. And Side effects reporting system should be established to guide safe medication use and treatment for patients. In order to establish side effects reporting system, the standardization of herbal drugs is needed.
박소정,강휘중,박지혜,조종관,유화승,Park, So jung,Kang, Hwi joong,Park, Ji hye,Cho, Chong kwan,Yoo, Hwa seung 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.1
Objective : This case report presents the effects of Gunchilgyebok-Jung to a patient who was clinically diagnosed with advanced lung cancer. Methods : The study involved a 74-year-old male patient clinically diagnosed with advanced (stage III) lung cancer by chest computed tomography (CT) and positron emission tomography. The patient had two masses (11.32 mm and $23.03mm{\times}35.34mm$) in the right upper lobe of the lung and in the mediastinum respectively. Gunchilgyebok-Jung commonly used for its anti-tumor and anti-inflammatory effect is composed of Rhus verniciflua stokes and Guizhifuling wan extracts. We prescribed Gunchilgyebok-Jung at a dosage of 1 g three times a day for 50 days. Results : After the administration of Gunchilgyebok-Jung, a decrease in tumor size to 10.69 mm and $22.71mm{\times}34.21mm$ on chest CT was observed. A numerical rating scale (NRS) showed an improvement in symptoms from points 7-8 to 3-4. Conclusion : This study suggests that Gunchilgyebok-Jung may have considerable anti-tumor and immunopotentiating activity in lung cancer without any adverse effects.
비소세포성 폐암 4기 환자의 악성흉수로 인한 증상이 이음전가미방으로 호전된 1례
박소정,강휘중,이연월,조종관,유화승,Park, So-Jung,Kang, Hwi-Joong,Lee, Yeon-Weol,Cho, Chong-Kwan,Yoo, Hwa-Seung 대한한방내과학회 2014 大韓韓方內科學會誌 Vol.35 No.3
Objectives: This is a report of a case of a stage IV non-small-cell lung cancer (NSCLC) patient whose malignant pleural effusion & respiratory symptoms have been relieved with Korean medicinal prescription, modified Yieum-jeon. Methods: A 56-year-old male diagnosed with stage IV NSCLC suffering malignant pleural effusion with complaints of cough, sputum, bilateral leg edema, dysphagia, post neck and left scapular pain was treated with modified Yieum-jeon and acupuncture during 16days. After treatment, blood lab and chest X-ray were used to follow the condition of malignant pleural effusion & pulmonary symptoms. Results: Malignant pleural effusion and pulmonary symptoms were improved with modified Yieum-jeon intake without any related adverse side effects. Conclusions: This study suggests Yieum-jeon may play a positive role in improving the malignant pleural effusion symptoms in advanced lung cancer cases.
비소세포폐암 환자의 종양 축소에 대한 SB 주사 효과 증례
박지혜,박소정,강휘중,조종관,한균인,유화승,Park, Ji Hye,Park, So Jung,Kang, Hwi Joong,Cho, Chong Kwan,Han, Kyun In,Yoo, Hwa Seung 대한암한의학회 2014 大韓癌韓醫學會誌 Vol.19 No.1
Objectives : To study the effect of SB injection on tumor size in an advanced non-small cell lung cancer patient. Methods : A patient was clinically diagnosed as advanced non-small cell lung cancer (Stage IIIa). Four cycles of intravenous SB injection were conducted. Each cycle lasted 4 days. The content of 7vials SB was injected every day. To compare the tumor size before treatment and after four cycles of SB injection, chest computed tomography (CT) was performed. Results : Follow-up CT images showed that the tumor size was reduced. In admission, size of the tumor $6.7{\times}8.5{\times}9.5cm$ on the left lower lobe of lung. After SB injection, size of the tumor $5.6{\times}6.8{\times}8.4cm$ by Chest CT. The patient's symptoms such as cough, sputum were improving until four cycles of SB injection. Numerical rating scale (NRS) showed improvement of Chest pain from point 3 to point 0. Conclusions : This case study suggests that intravenous SB injection may have significant effects of anti-tumor for non-small cell lung cancer.
이부균,임규상,강휘중,이장천,Lee, Boo-Kyun,Lim, Kyu-Sang,Kang, Hwi-Joong,Lee, Jang-Cheon 대한한의학방제학회 2012 大韓韓醫學方劑學會誌 Vol.20 No.1
Objectives : The purpose of this study is to find out herb-pair prototype composed of Zanthoxyli Fructus, to examine compatibility regulation between them and to classify them into seven features of compatibility. Methods : To search usages of Zanthoxyli Fructus compatibility, we have investigated the classics of herb and prescription such as "五十二病方"(Fifty-two kinds of Diseases), "黃帝內經"(The Medical Classic of Yellow Emperor), "傷寒論"(Treatise on Febrile Caused by Cold), "金?要略"(Synopsis of Prescriptions of The Golden), "附廣?后方"(Handbook of Prescriptions for Emergencies), "本草綱目"(Compendium of Materia Medica), "得配本草"(Deukbae Materia Medica). Results : In these books Zanthoxyli Fructus was paired with below herbs; 桂(Cinnamomi Cortex), 薑(Zingiberis Rhizoma), 吳茱萸(Evodiae Fructus), 細辛(Asari Radix), 茴香(Foeniculi Fructus), 肉荳?(Cistanches Herba), 釜下土(Terba Flava Usta), 益智仁(Alpinae Oxyphyllae Fructus), 飴(Saccharum Granorum), ?白(Allii Radix), 梨(Pyrus), 牙?(Gleditsia Fructus), 杏仁(Armeniacae Amarum Semen), 蕎麥粉(Fagopyrum esculentum Moench), 胡粉(Minium), 白朮(Atractylodis Rhizoma White), 蒼朮(Atractylodis Rhizoma), 麻子仁(Cannabis Fructus), 大麥蘗(Hordei Fructus Germiniatus), 麴(Massa Medicata Fermentata), 生地黃(Rehmanniae Radix), 茯?(Poria), 牡?(Ostreae Concha), 白礬(Alumen), 雄黃(Realgar), 烏頭(Aconiti Radix), 附子(Aconiti Lateralis Preparata Radix). Conclusions : Zanthoxyli Fructus herb-pair classified by seven features of compatibility are as follows; 1. Mutual reinforcement compatibility with : Cinnamomi Cortex, Zingiberis Rhizoma, Evodiae Fructus, Asari Radix, Foeniculi Fructus, Cistanches Herba, Terba Flava Usta, Alpinae Oxyphyllae Fructus, Saccharum Granorum, Allii Radix, Pyrus, Gleditsia Fructus. 2. Mutual assistance compatibility with : Armeniacae Amarum Semen, Fagopyrum esculentum Moench, Minium, Atractylodis Rhizoma White, Atractylodis Rhizoma, Cannabis Fructus, Hordei Fructus Germiniatus, Massa Medicata Fermentata, Rehmanniae Radix, Poria, Ostreae Concha, Alumen. 3. Mutual restraint compatibility with: Realgar, Aconiti Radix, Aconiti Lateralis Preparata Radix) 4. Mutual detoxication compatibility with: 桑汁(Juice of Mori Folium), 桑根汁(Juice of Morus Cortex), 大蒜(Allii Bulbus), 薺?(Remotiflori Radix), 桂汁(Juice of Cinnamomi Cortex).
한약처방을 사용한 치매에 대한 실험연구 동향분석 -국내 학위논문을 중심으로-
조희근 ( Hee Geun Jo ),강휘중 ( Hwi Joong Kang ),고용준 ( Yong Jun Go ),박진우 ( Jin Woo Park ),박수곤 ( Soo Gon Park ),정필선 ( Pil Sun Jung ),이상영 ( Sang Young Lee ),설재욱 ( Jae Uk Sul ),정민영 ( Min Young Jung ),문영호 ( You 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.4
ObjectivesThis study was designed to collect basic information about the herbal medi-cine used for dementia through analysis on Korean medicine prescriptions used in dis-sertations for a degree of Korean medicine related dementia (experimental study).MethodsWe searched dissertations in the National Assembly Library and oriental medi-cine advanced searching integrated system web DB by using keyword ``치매`` and ``de-mentia``. We reviewed and analyzed dissertations for the degree of Korean medicine, pub-lished from 2000 to 2013.ResultsAs a result, We found 36 dissertations about Korean herbal medicines used for Dementia Yukmijihwang-tang, Chenwangbosim-dan were used much more than other pre-scriptions and Panax ginseng, Glycyrrhiza uralensis, Acorus gramineus, Polygala tenuifolia, Pachyma hoelen were used more than 10 times in these dissertations.ConclusionsIn relieving symptoms and the treatment of dementia, it is difficult to find tendency. Because the purpose and perspective of using each Korean medicine pre-scriptions and their herbs are various. However, as referred to outcome of preceding re-searches, Yukmijihwang-tang is considered as a potential dementia medicine. (J Korean Med Rehab 2014;24(4):29-40)
한방 치료로 수술 및 방사선 치료 후 부작용 완화를 이룬 후복막 지방육종 환자 2례의 보고
배겨레,김지혜,박지혜,박소정,강휘중,조종관,유화승,Bae, Kyeore,Kim, Ji-Hye,Park, Ji-Hye,Park, So-jung,Kang, Hwi-joong,Cho, Chong-kwan,Yoo, Hwa-seung 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.2
Objectives : Retroperitoneal liposarcoma (RPS) is a rare solid tumor and has a high recurrence rate after surgery. New complementary and alternative medicine is required to manage symptoms of RPS and side effects of surgery, chemotherapy and radiation therapy. The purpose of this case report is to report two cases of reduction of side effects of surgery and radiation therapy in RPS treated with Wheel Balanced Therapy (WBT) which is a traditional Korean medicine treatment program for patients with cancer. Methods : Two patients with RPS were treated with WBT. Each of patients received personalized WBT schedule including acupuncture. The changes in clinical and laboratory findings were evaluated. Results : The symptoms of patients were improved after about 2 weeks hospitalization. Conclusions : This case report suggests that WBT has a potential to treat side effects of surgery and radiation therapy in patients with RPS. Further rigorous studies are necessary to investigate the therapeutic effects of WBT on RPS.
동의보감(東醫寶鑑) 중 고마요법(膏摩療法)에 사용된 방제(方劑)에 대한 고찰(考察)
이부균,임강현,박성하,강휘중,이장천,Lee, Boo-Kyun,Leem, Kang-Hyun,Park, Seong-Ha,Kang, Hwi-Joong,Lee, Jang-Cheon 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.2
The purpose of this study is to expand the prescription usage from internal treatment to external treatment by applying the compatibilities of herbal ingredient for ointment massage therapy. For this, specific cases of usage were investigated in Donguibogam, which is now inscribed on the UNESCO Memory of the World Register, has been not only one of the classics of Korean medical asphere, but has compiled all the contents of the Oriental medical traditions including ointment massage therapy that was completed through different Chinese dynasties, such as Song (宋), Jin(金) and Won(元) by the 17th century. Research results of this study is : 1. Ointment Massage Therapy was used to treat the symptoms of diseases such as ACHI-mun(dental range : 牙齒門), PI-mun(dermal range : 皮門), JECHANG-mun (sore range : 諸瘡門), SO A-mun(pediatrics range : 小兒門). 2. Out of all the manipulations, it is a scrubbing manipulation that used most. 3. Out of all the formulations of ointment massage therapy, it is powder types and ointment types that most representative formulation.