이압요법이 남자 고등학생의 금연에 미치는 효과

강자연,이종훈,강세영,Kang, Ja-yeon,Lee, Jong-hoon,Kang, Sei-young 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.3

Objective: The purpose of the study was to examine the effects of a five-week auricular acupressure (AA) program on smoking cessation for male high school students.Methods: From May 27 2015 to November 18 2015, this study investigated 66 high school students who had been smoking. More than four sessions of AA were given to participants, and surveys were conducted before each treatment. Once a week, the AA was administered at the endocrine point, lung point, throat point, nasal fossae point, bronchial tube point, and mouth point.Result: Thirty-four (51.5%) students reduced their number of cigarettes smoked per day, while 17 (25.7%) students complained of side effects.Conclusions: Results show that AA is generally effective, and side effects occur less often than with anti-smoking acupuncture. So AA could be preferred on smoking cessation for students.

프락셔널 레이저 치료와 한의치료를 병행한 욕창치료 1례

강자연,이기향,장인수,김홍준,정민정,서형식 대한한방안이비인후피부과학회 2018 한방안이비인후피부과학회지 Vol.31 No.4

Objectives : The purpose of this report to represent the efficacy of pressure ulcer treatment with fractional laser therapy and Korean medicine. Methods : We treated Parkinsonism patients with pressure ulcer using herbal medicine, fractional mode laser therapy, acupuncture and simple dressing for 3 weeks. Laser was set on fractional mode (on time 100 ㎲, dot pitch 0.6 ㎜, shape RECT) and irradiated around pressure ulcer site and center of pressure ulcer site once a day. The treatment effect was evaluated by The National Pressure Ulcer Advisory Panel(NPUAP) stage and the The Pressure Ulcer Scale for Healing(PUSH) tool(3.0). Results & Conclusions : Pressure ulcer site have improved markedly. NPUAP stage was improved from 2 to 1 and total score of the PUSH tool decreased from 12 to 8. Even though the wound was not cured completely, this shows that fractional laser therapy and Korean medicine could be effective treatment for improving pressure ulcers.

고혈압 한의 진료 실태조사

강자연,강기완,정민정,김홍준,장인수,Kang, Ja-yeon,Kang, Ki-wan,Jeong, Min-jeong,Kim, Hong-jun,Jang, In-soo 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.6

Objectives: This study surveyed doctors of Korean medicine on how they treat hypertension in their Korean clinical practices. Methods: An invitation to take an Internet-based questionnaire was sent to doctors who were registered in the Association of Korean Medicine in September 2016. Participants were first asked general profile questions, which included age, gender, work experience as a practitioner, and specialties. Second, they were asked whether they had experience with hypertension treatment and additional questions related to hypertension. Results: A total of 991 replies were received to the questionnaire. Most of the Korean medical doctors (95%) had blood pressure units and had monitored blood pressure. A majority of the Korean medicine doctors (55%) had provided hypertension treatment. Acupuncture and herbal medicine were commonly used for the treatment of hypertensive patients. In addition, bloodletting, moxibustion, pharmacopuncture, cupping, Chuna, Qigong exercise, meditation, and Tai Chi were used. Many doctors also recommended lifestyle modification. The respondents said that Korean medicine improves general health conditions (42.6%) and has low adverse effects (29.9%). One of the most common opinions about the revitalization measures of Korean medicine was expanding health insurance benefits (20.8%). Conclusions: Through this survey, we found out information about the present situation of hypertension treatment in Korean medicine. In the future, it is possible that hypertension treatment using Korean medicine will be demanded and used by practitioners if it is covered by public health insurance.

고혈압에 대한 한약 이수 처방 효과에 대한 체계적 문헌 고찰 및 메타분석

강자연,강기완,정민정,김홍준,장인수 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.6

Objectives: The aim of this study was to review the clinical research on antihypertensive effects of Korean herbal medicines that function by inducing diuresis. Methods: Literature searches were performed using PubMed, Cochrane, CNKI, Wanfang, Cinii, Oasis, KISS, NDSL, RISS, DBPia, with the keywords “利水”, “利尿”, “高血壓”, “hypertension”, and “lishui.” The search range included only randomized controlled trials that verified the effects of Korean herbal medicine interventions on hypertension. The selected studies were assessed by risk of bias (RoB). Results: 26 reports were selected from a total of 532 identified. For these reports, meta-analysis was performed using Revman 5.3. From this analysis, it was observed that the combined treatment of Korean medicine and antihypertensive drugs had a significantly higher total effective rate (TER) and improvement in systolic blood pressure (SBP) and diastolic blood pressure (DBP) than did the use of a single antihypertensive drug. The risk ratio of TER for lowering blood pressure was 1.25. The mean differences of SBP, DBP were -19.63 mm Hg (95% confidential interval (CI), -22.45 mm Hg, -16.80 mm Hg, p<0.00001), and -5.39 mm Hg (95% CI, -7.36 mm Hg, -3.42 mm Hg, p<0.00001) respectively. The use of Korean medicine only did not improve blood pressure, as compared to the use of an antihypertensive drug. Most of items of RoB were unclear, and the methodological quality was low. Conclusions: The combination of antihypertensive drugs and Korean medical treatment can effectively improve SBP, DBP, and TER. This finding could be widely utilized in clinical practice in Korean medicine.

PET 기판 위에 SiO₂ 버퍼층 증착에 따른 ITO 박막의 부착 및 전기적 광학적 특성 연구

강자연(Ja-youn Kang),김동원(Dong-won Kim),조규일(Dong-won Kim),우병일(Byung-il Woo),윤환준(Hwan-jun Yun) 한국표면공학회 2009 한국표면공학회지 Vol.42 No.1

Using an evaporation system, SiO₂ was deposited as a buffer layer between a PET substrate and a ITO layer and then ITO/SiO₂/PET layers were annealed for 1.5 hours at the temperature of 180℃. Adhesion and electro-optical properties of ITO films were studied with thickness variance of a SiO₂ buffer layer. As a result of introduction of the SiO₂ buffer layer, sheet resistance and resistivity increased and a ITO film with optimum sheet resistance ( 529.3 Ω/square) for an upper ITO film of resistive type touch panel could be obtained when SiO₂ of 50 A was deposited. And it was found that ITO films with SiO₂ buffer layer have higher transmittance of 88~90% at 550 ㎚ wavelength than ITO films with no buffer layers and the transmittance was enhanced as SiO₂ thickness increased from 50 A to 100 A. Adhesion property of ITO films with SiO₂ buffer layers became better than ITO films with no buffer layers and this property was independent of SiO₂ thickness variance (50~100 A). By depositing a SiO₂ buffer layer of 50 A on the PET substrate and sputtering a ITO thin film on the layer, a ITO film with enhanced adhesion, electro-optical properties could be obtained.

고혈압에 대한 천마구등음의 효과 : 체계적 문헌고찰과 메타분석

강기완,강자연,정민정,김홍준,선승호,장인수 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.1

Objective: The purpose of this study is to investigate the effect of Cheonmagudeung-eum (CGE) for essential hypertension by systematic review and meta-analysis. Methods: The period of literature search was until October 30, 2016, and 14 electronic databases were utilized as search engines. The evaluation for the risk of bias (RoB) was conducted by using the Cochrane Risk of Bias Tool. The meta-analysis was performed by synthesizing outcome data, including total effective rate (TER), systolic blood pressure (SBP), diastolic blood pressure (DBP), and the incidence of adverse events. Result: There were a total of 64 RCTs using CGE on adult essential hypertension. In the RoB evaluation, most of the items were unclear, and the qualities of studies were rated low. The concurrent treatment of CGE and antihypertensive drug (AHD) showed a significant hypotensive effect since the risk ratio (RR) of TER was 1.17 times (95% CI 1.14, 1.20, p<0.01) higher than that of AHD alone. In addition, the mean difference (MD) appeared low as 8.73 mm/Hg in SBP (95% CI -11.36, -6.09, p<0.01) and 5.81 mm/Hg in DBP (95% CI -7.50, -4.12, p<0.01). Conclusion: Through this study, it was identified that the combined treatment of CGE and AHD on hypertension would be more effective than that of AHD treatment alone. However, due to the low quality of the selected original articles, the significance of this conclusion is somewhat limited, and we hope that this would be complemented through more rigorous RCTs in the future.

당뇨병성 궤양의 레이저치료에 대한 효과 : 체계적 문헌고찰

강기완,강자연,정민정,김홍준,서형식,장인수,Kang, Ki-Wan,Kang, Ja-Yeon,Jeong, Min-Jeong,Kim, Hong-Jun,Seo, Hyung-Sik,Jang, In-Soo 대한한방안이비인후피부과학회 2017 한방안이비인후피부과학회지 Vol.30 No.4

Objectives : The purpose of this study is to investigate the effect of laser therapy for diabetic ulcer by using methods of systematic review. Methods : In this review, PubMed, Cochrane library, Web of Science, CNKI, CiNii, J-STAGE, NDSL and OASIS were used as the search engines. The search period is from the start date of the search engine to October 3, 2016. Randomized controlled trials(RCTs) using laser therapy for diabetic ulcer were searched and extracted by two independent researchers. Risk of bias(RoB) of Cochrane was used to assess methodological quality of studies. Results : Finally, five RCTs were selected. The follow-up period ranged from 15 days to 20 weeks. InGaAlP laser, GaAlAs laser and light emitting diode(LED) were used to treat diabetic ulcer. The clinical trials used sham laser irradiation or standard treatment as control in comparison to laser therapy. The endpoints included ulcer size, rate of healing and time to healing with follow-up period. The RCTs demonstrated therapeutic outcomes with no adverse effect. Most items of RoB were unclear and methodological quality was low. Conclusions : Our analysis suggests that laser therapy has therapeutic effects for diabetic ulcer. However, more systematic and stringent clinical trials will be required.

당뇨병성 궤양에 사용되는 레이저의 특성에 대한 연구

강기완,강자연,정민정,김홍준,서형식,장인수,Kang, Ki-wan,Kang, Ja-yeon,Jeong, Min-jeong,Kim, Hong-jun,Seo, Hyung-sik,Jang, In-soo 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.4

Objectives : One of major complications of diabetes, diabetic ulcer is also one of the main reasons for amputation, and the prevalence rate is 4-10%. Laser therapy is widely used for leg ulcer and diabetic ulcer, and it is known to improve wound epithelialization, cellular content, and collagen deposition. The purpose of this study is to investigate the properties of the laser and the spectrum of laser instruments for diabetic ulcer. Methods : We performed literature search using the PubMed, Cochrane, CINAHL and Web of science for the data in English. In addition, other databases were checked for different languages such as OASIS and NDSL for the literature in Korean, CNKI in Chinese, and CiNii and J-STAGE written in Japanese. We excluded all review article and experimental studies, and only clinical studies using laser or light emitting diode (LED) for diabetic ulcer were selected. Results : A total twenty papers were selected. Different light sources were used as follows: LED, HeNe, InGaAlP, GaAlAs, GaAs, CO2, and KTP. The number of LED studies was 9, and HeNe laser was 7, and InGaAlP and GaAlAs laser was 2, GaAs, CO2, and KTP laser was 1 for each. Various energy density of the clinical study were reported. Conclusions : It is suggested that to select appropriate laser type and give the adequate output power to treat diabetic ulcer. Further evaluation and research for the condition of laser therapy to treat diabetic ulcers are warranted.

오령산의 고혈압 치료약물 가능성에 대한 개관

정민정,강기완,강자연,윤지현,최유민,김홍준,선승호,장인수,Jeong, Min-jeong,Kang, Ki-wan,Kang, Ja-yeon,Yoon, Jee-hyun,Choi, Yoo-min,Kim, Hong-jun,Sun, Seung-ho,Jang, In-soo 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This study assessed the application of Oryung-san (Wuling-san or Gorei-san), a common diuretic in traditional medicine, as an antihypertensive agent. Methods: Experimental studies of the pharmacological properties of Oryung-san, including diuretic action and lowering effects on blood pressure, and toxicology and clinical trials were reviewed. Results: In pharmacology, various, relatively safe diuretics are used to lower blood pressure and are the oldest and most studied antihypertensive agents. Despite many new drug approvals, antihypertensive diuretics are frequently used in Korea and Japan where high levels of sodium uptake are common. Oryung-san has been demonstrated to have diuretic, antihypertensive, and nephroprotective effects. Conclusions: Oryung-san might be effective for lowering blood pressure based on the results of this literature review. Further evaluations and large-scale clinical trials of Oryung-san to treat primary hypertension are warranted.

일개 한의원의 고혈압 한의치료 118례에 대한 고찰

정용욱,이기향,강자연,정민정,김홍준,장인수,Jeong, Yong-wook,Lee, Gi-hyang,Kang, Ja-yeon,Jeong, Min-jeong,Kim, Hong-jun,Jang, In-soo 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4

Objectives: The aim of this study was to report a 118-case series demonstrating the treatment of hypertension in a Korean medicine clinic and to evaluate the effect of Korean medicine. Materials & Methods: From 2006 to 2018, patients who visited a Korean medicine clinic for hypertension were investigated by studying changes in blood pressure before and after treatment with herbal medicine, acupuncture, and Uwhangchungsim-won. The average treatment period was 81.6 days. Results: After treatment with Korean medicine, the mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) of all patients decreased significantly (p<0.001). The SBP decreased from $148.9{\pm}10.3$ to $133.8{\pm}13.9$, and the DBP decreased from $91.3{\pm}7.5$ to $82.5{\pm}9.0$. After treatment with acupuncture or Uwhangchungsim-won, the patient showed decreased blood pressure but the differences were not statistically significant when compared with the non-treated group. Conclusions: This study shows the real situation of hypertension treatment in Korean medicine and indicates that Korean medicine could be one of the primary treatment for hypertension. However, this study had limitations, such as variations in the treatment periods, the frequency of acupuncture treatments, and the type of antihypertensive drugs. For further evaluation of the effectiveness of treatment for hypertension using Korean medicine, a well-designed study should be undertaken.