임상연구 : 불임 환자에게 시행되는 난자 채취 시 Fentanyl과 Alfentanil을 이용한 정맥 마취의 비교

강용인 ( Yong In Kang ),방은치 ( Eun Chi Bang ),이현숙 ( Hyun Sook Lee ),조경숙 ( Kyung Sook Cho ),김수연 ( Su Yeon Kim ),설정호 ( Jung Ho Sul ),김준영 ( Jun Young Kim ),윤태기 ( Tae Gi Yoon ),석현하 ( Hyun Ha Seok ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.55 No.5

Background: This study was carried out to compare the effect of intravenous anesthesia with fentanyl or alfentanil on the hemodynamic profile, sedation, recovery and side effect in the patients undergoing oocyte retrieval. Methods: The patients were designed to receive alfentanil (group A, n=70) or fentanyl (group F, n=70) intravenous anesthesia. The patients were given midazolam 0.6 mg/kg and alfentanil 15 μg/kg in group A or fentanyl 1.5 μg/kg in group F. Propofol 0.7 mg/kg was given if patient was awaken during procedure. Hemodynamic changes, propofol used dosage and initial propofol injecting time, Ramsay Sedation Scales, cough reflex on opioid injection, recovery time, duration of apnea and postoperative nausea, vomiting at the recovery room were recorded. Results: Group A had rapid onset, deep sedation, less amount of propofol used, more frequent apnea than group F. There were no significant differences in postoperative nausea, vomiting and recovery time between the two groups. Conclusions: The intravenous anesthesia with fentanyl or alfentanil are suitable for oocyte retreival but apnea happened more frequent in alfentanil group, so the use of alfentanil needs to monitor ventilation and hemodynamic changes carefully. (Korean J Anesthesiol 2008;55:543~8)

핵의학과 검체 접수 환경시스템의 개선사례 보고

김정인,강미지,김나경,박지솔,권원현,이경재,Kim, Jung In,Kang, Mi Ji,Kim, Na Kyung,Park, Ji Sol,Kwon, Won Hyun,Lee, Kyung Jae 대한핵의학기술학회 2021 핵의학 기술 Vol.25 No.2

Purpose Sample reception environment system in nuclear medicine has not changed much compared to 20 years ago. When preparing sample for in vitro test, there was no significant change because the test was carried out by generating an own specimen from the parent specimen. In this study, We would like to introduce a method that automatically removes the sample cap using the automated decapper equipment and enables automatic reception at the same time. In addition, including a provisional reception system. Materials and Methods In 2019, it was intended to get a device that automatically removes the cap of a patient's blood sample. This equipment is the same as the equipment used in the Department of Laboratory Medicine (Vacuette Ⓡ Unicap Belt Decapper, Greiner bio-one, Austria). However, the purchase was delayed due to differences in tube size, budget, and space. In January 2020, we borrowed domestic automatic decapper equipment and modified it to suit our laboratory environment. After 9 months, we were able to introduce a system that automatically removes the lid of a patient's blood sample and at the same time automatically accepts the test. And, through the provisional reception system, it was possible to know the arrival of the specimen in a short time. Results With the use of an automatic decapper device, the sample cap was automatically removed, and the reception proceeded at the same time. So, it was very efficient at work because it shortened the sample preparation time by about 20 minutes. In addition, it was possible to prevent the examiner's musculoskeletal disorders caused by repeated wrist use. After using the provisional reception system, patients were able to be discharged quickly, and the number of phone calls to confirm the arrival of samples was reduced. Conclusion Most hospitals have about four employees in the nuclear medicine in vitro laboratory. It is effective to use automatic decapper equipment and a provisional reception system for organizations that perform work with the minimum number of personnel. 핵의학과 검체 접수 환경시스템은 20년 전과 비교하여 보았을 때 크게 달라지지 않은 채 동일한 시스템으로 검체 접수 업무가 이루어지고 있다. 핵의학과 검사 특성상 진단검사의 학과와 달리 검체 용기 자체로 검사가 시행되는 것이 아니라 모검체에서 자검체를 생성하여 검사를 시행하는 시스템이기 때문에 지금까지 큰 변화 없이 이어져 온 것으로 보인다. 본원에서는 이러한 검체 접수 환경시스템을 개선하고자 검체의 뚜껑을 자동으로 제거해 주고 동시에 자동접수가 가능한 decapper 자동화 장비를 도입한 사례와 가접수 시스템 적용 사례에 대해서 소개해 보고자 한다. 본원에서는 2019년 환자의 검체 뚜껑을 자동으로 제거해 주는 장비를 도입하고자 진단검사의학과 응급검사실에서 사용하는 Vacuette ® Unicap Belt Decapper(Greiner bio-one, Austria) 제품을 벤치마킹하여 구매를 시도하였으나 5 ml SST, 8 ml SST 튜브를 사용하는 핵의학과 검체를 처리하려면 2대의 장비가 필요하여 예산과 공간 문제에 부딪혀 구매가 지연되었다. 2020년 1월 국산 decapper 자동화 장비를 대여 받아 검체 검사실 접수 실정에 맞게 지속적인 아이디어 제공과 테스트로 수정 보완하여 2020년 10월 검체 뚜껑을 자동으로 제거해 주는 동시에 자동접수 해주는 decapper 자동화 장비를 도입하게 되었다. 또한 검체 접수 전 단계에서 가접수 시스템을 도입하여 병동과 응급실, 건강증진센터 이송사원이 검체를 갖고 검사실에 도착하면 검체를 셀프로 가접수 하여 빠른 시간 내에 검체 도착 여부를 알릴 수 있도록 개선하였다. Decapper 자동화 장비가 도입되면서 자동으로 검체 뚜껑이 제거되고 접수되는 순간에 다른 업무를 수행할 수 있게 되어 검사자의 업무 효율성을 크게 증대 시킬 수 있었고 검사 소요시간에 영향을 미칠 수 있는 검체 접수 마감시간이 단축되어 검사시작을 10분~20분 정도 단축시킬 수 있는 효과를 볼 수 있었다. 또한 반복된 손목 사용으로 인하여 발생되는 근골격계 질환의 감소로 검사자의 건강장해를 예방할 수 있었다. 가접수 시스템을 설치한 후 병동에서는 빠른 퇴원이 가능해졌고 검체 도착 여부를 묻는 불필요한 전화문의 횟수도 감소하게 되었다. 대부분의 핵의학과 검체 검사실은 소규모의 인력으로 운영되고 있는 것이 현실이다. 최소 인력으로 검체 검사와 검체 접수 업무를 동시에 수행해야 되는 소규모 기관에서는 decapper 자동화 장비와 가접수 시스템을 도입 시 업무를 보다 원활히 수행하는데 도움이 될 수 있을 것으로 사료된다.

강박장애 환자의 반응억제 결함

부영준,김세주,강지인,Boo, Young Jun,Kim, Se Joo,Kang, Jee In 대한불안의학회 2015 대한불안의학회지 Vol.11 No.1

Objective : Impaired response inhibition has been suggested to play an important role in the pathophysiology of obsessive-compulsive disorder (OCD). The aim of this study was to evaluate the response inhibition in patients with OCD, by using the Go/NoGo paradigm, and to better understand its associations with clinical symptoms. Methods : The participants included 63 OCD patients and 80 healthy volunteers matched in age and sex. response inhibition was evaluated using computerized Go/NoGo task, in which their commission error rates, omission error rates, and mean response times were measured. The severity of clinical symptoms in the OCD patients was assessed using Montgomery-Asberg Depression Scale and Yale-Brown Obsessive Compulsive Scale. Result : OCD patients showed significantly impaired inhibition and higher omission errors rates despite their slower response time, compared to normal controls. Clinical symptoms were not correlated with commission errors and omission errors. Conclusion : The present results indicate that impairment in response inhibition may play a critical role in the pathophysiology of OCD as a trait. These findings suggest that deficit of response inhibition may contribute to developing and maintaining clinical symptoms such as compelling need to repeat certain actions in patients with OCD.

저널치료를 통한 청소년들의 자기이해 경험에 대한 현상학적 연구

장정인(Jeong-In Jang),강금해(Keum-Hae Kang) 한국상담심리교육복지학회 2020 상담심리교육복지 Vol.7 No.2

본 연구의 목적은 현상학적 연구방법을 통해 저널치료 프로그램에 참여한 청소년들의 자기이해 경험을 심층적으로 이해하는 것이다. 중·고생으로 구성된 13명의 청소년들과 함께 저널쓰기를 한 후, 개별심층면담을 실시하여 청소년들의 자기이해 경험을 현상학적으로 분석하였다. ‘저널치료를 통한 청소년들의 자기이해 경험’을 주제로 한 연구결과는 저널쓰기의 의미, 자신의 꿈에 대한 이해, 감정에 대한 이해, 관계에 대한 이해로 범주화되었다. 본 연구결과, 저널쓰기를 통해 청소년들은 자신을 성찰하며 자기를 이해함으로써 자신의 꿈에 대해 고민하고 있다는 것을 알 수 있다. 또한 자신의 감정표현에 어려움을 느끼지만 이를 극복함으로써 더 나은 청소년기를 보내기를 희망하고 있었다. 마지막으로 친구관계의 소중함과 부모님과의 관계에 대해 되돌아보게 되었음을 알 수 있었다. 저널치료 프로그램을 통해 청소년들이 자신을 더 깊이 이해하고 사랑하게 됨으로써 앞으로의 삶의 주인공의 역할을 할 수 있을 것이다. The purpose of this study is in-depth understanding of self-understanding experiences of adolescents who participated in journal therapy program through phenomenological research method. After letting 13 middle and high school students write journals, individual in-depth interviews were conducted to analyze the self-understanding experiences of the teenagers phenomenologically. The research results on the subject of the self-understanding of youth through journal therapy were categorized into the meaning of journal writing, understanding of their dreams, understanding of emotions, and understanding of relationships. As a result of this study, it was found that youths are thinking about their dreams by reflecting on themselves and understanding themselves in the process of journal writing. In addition, although they were having difficulties in expressing their emotions, they hoped to overcome it and have a better youth. Lastly, it was found that they were looking back on the importance of friendship and their relationship with their parents. Through the journal therapy program, young people can understand and love themselves in a deeper way, and they will be able to serve as the main characters of their future lives.

흰쥐에서 난소제거술로 유발시킨 골다공증에 유효한 기능성성분을 배합한 P 식이의 효능

서지혜(Ji He Seo),임병우(Beong Ou Lim),강순아(Sun A Kang),한인권(In Kwon Han),박동기(Dong Ki Park) 대한폐경학회 2002 대한폐경학회지 Vol.8 No.1

N/A The aim of this investigation was to examine the effects of serum alkaline phosphatase, phosphorous, calcium and bone mineral density in P diet on osteoporosis induced by ovariectomy in rats. Female Sprague-Dawely 20 rats of weighting 249±29g, were divided into four groups including the sham operation groups (5 heads) and ovariectomy groups (15 heads). They were fed low calcium diets for 4 weeks after experimental operation and 12 more weeks. The experimental group received a daily administration of P diet for 4 and 8 weeks after oophorectomy. Therefore, we measured levels of calcium, alkaline phophatase (ALP), phosphorous, trabecular density of tibia, ash weights in tibia and femur. The level of serum ALP of P diet was showed a significant decrease in comparison with sham group. Calcium and phosphorous were almost not changed between three groups. The weight of tibia and femur of P diet was increased in comparison with sham group in 8 week after oophorectomy. The trabecular bone density in ovariectomy group showed significant decrease in comparison with sham. Those in P diet-treated showed significant increase in comparison with sham after oophorectomy. Accordingly to the above results, effects of the P diet on the rat osteoporosis showed a efficiency in elevation of bone density by increasing bone weight by ovariectomy. So P diet can be used for preventing and curing of the postmenopausal osteoporosis, as for it's effects, continuous clinical study is needed.

연구논문 : Aspergillus oryzae로 발효한 자색당근을 첨가한 발효유의 품질 및 관능 특성에 관한 연구

신배근 ( Bae Keun Shin ),강선아 ( Suna Kang ),한정인 ( Jung In Han ),박선민 ( Sunmin Park ) 한국식생활문화학회 2015 韓國食生活文化學會誌 Vol.30 No.3

In this study, we compared the organoleptic and other qualities of fermented milk containing 10 or 15% purple carrot extract that had either been previously fermented with Aspergillus oryzae or not fermented. Fermentation characteristics, pH, chromaticity, viscosity, viable cell counts, and sensory evaluations were measured. The pH and acid values did not differ between purple carrot extract fermented with Aspergillus oryzae and non-fermented extract. Viable cell counts were significantly higher in 15% purple carrot extract fermented with Aspergillus oryzae compared to the control after fermentation. Regarding characteristic changes, purple carrot extract fermented with Aspergillus oryzae group showed a lower red value but higher yellow value compared with non-fermented purple carrot extract due to heat-sterilization. Both fermented and non-fermented extract groups showed significantly increased viscosity compared to control. In the sensory evaluation, 15% purple carrot extract fermented with Aspergillus oryzae showed the highest score. In conclusion, addition of 15% purple carrot extract fermented with Aspergillus oryzae resulted in a superior fermented milk product.

CDMA 이동통신 시스템용 기지국 변조기 ASIC 설계 및 구현

강인,현진일,차진종,김경수,Kang, In,Hyun, Jin-Il,Cha, Jin-Jong,Kim, Kyung-Soo 대한전자공학회 1997 電子工學會論文誌, C Vol.c34 No.2

We developed a base station modulator ASIC for CDMA digital cellular system. In CDMA digital cellular system, the modulation is performed by convolutional encoding and QPSK with spread spectrum. The function blocks of base station modulator are CRC, convolutional encoder, interleaver pseudo-moise scrambler, power control bit puncturing, walsh cover, QPSK, gain controller, combiner and multiplexer. Each function block was designed by the logic synthesis of VHDL codes. The VHDL code was described at register transfer level and the size of code is about 8,000 lines. The circuit simulation and logic simulation were performed by COMPASS tools. The chip (ES-C2212B CMB) contains 25,205 gates and 3 Kbit SRAM, and its chip size is 5.25 mm * 5,45 mm in 0.8 mm CMOS cell-based design technology. It is packaged in 68 pin PLCC and the power dissipation at 10MHz is 300 mW at 5V. The ASIC has been fully tested and successfully working on the CDMA base station system.

실리콘 나노와이어 MOSFET의 고주파 모델링

강인만(In Man Kang) 大韓電子工學會 2010 電子工學會論文誌-SD (Semiconductor and devices) Vol.47 No.9

본 논문에서는 30 ㎚ 채널 길이와 5 ㎚의 채널 반지름을 갖는 실리콘 기반의 나노와이어 MOSFET의 고주파 모델링을 다루고 있다. 3차원 소자 시뮬레이션을 이용하여 실리콘 나노와이어 MOSFET의 Y-parameter와 Z-parameter를 100 ㎓까지 확보하였으며 이를 이용하여 모델 파라미터에 필요한 수식을 구하였다. 모델과 파라미터 추출 수식을 이용하여 회로 검증용 tool인 HSPICE에 의하여 검증이 이루어졌으며 quasi-static 기반의 고주파 모델이 100 ㎓의 높은 주파수까지도 소자의 특성을 정확히 예측함을 확인하였다. 모델 검증은 MOSFET의 포화 영역 (V<SUB>gs</SUB> = V<SUB>ds</SUB> = 1 V)과 선형 영역 (V<SUB>gs</SUB> = 1 V, V<SUB>ds</SUB> = 0.5 V)의 바이어스 조건에서 이루어졌으며 두 바이어스 조건에서의 Y-parameter에 대한 모델의 오차는 약 1 %로 매우 작은 값을 보여 준다. This paper presents the RF modeling for silicon nanowire MOSFET with 30 ㎚ channel length and 5 ㎚ channel radius. Equations for analytical parameter extraction are derived by analysis of Y-parameter. Accuracies of the new model and extracted parameters have been verified by 3-dimensional device simulation data up to 100 ㎓. The model verifications are performed under conditions of saturation region (V<SUB>gs</SUB> = V<SUB>ds</SUB> = 1 V) and linear region (V<SUB>gs</SUB> = 1 V, V<SUB>ds</SUB> = 0.5 V). The RMS modeling error of Y-parameters was calculated to be 1 %.

급성기 족관절 염좌 환자에 대한 치료방법에 따른 효과 비교 연구 - 체침, 봉약침, 황련해독탕 약침액을 통해 -

강인,문자영,임명장,조재희,이효은,Kang, In,Moon, Ja-Young,Lim, Myung-Jang,Cho, Jae-Hee,Lee, Hyo-Eun 대한침구의학회 2008 대한침구의학회지 Vol.25 No.5

Objectives : This study was aimed at comparing clinical effectiveness among dry needle, Bee Venom Acupuncture, Hwangryunhaedoktang Herbal Acupuncture for treating acute ankle sprain. Methods : The subjects in this study were sixty patients with lateral ankle pain who came to Jaseng Hospital of Oriental medicine from Oct. 28. 2007 to Jul. 14. 2008. Among them, the number of patients after 3 session of each treatment was 17 with dry needle, 18 with Bee Venom Acupuncture, 17 with Hwangryunhaedoktang Herbal Acupuncture, and they were evaluated with Numerical Rating Scale(NRS), and Ankle-Hindfoot Scale(AHS) before and after every session of treatment. Results : 1. Each group had significant decrease in NRS(P<0.05) and increase in AHS score(P>0.05) after 3 session of each treatment. 2. There was no significant difference among 3 groups after 3 session of each treatment. Conclusions : When treating patients with acute ankle pain, Acupuncture, Bee Venom Acupuncture, Hwangryunhaedoktang Herbal Acupuncture each has clinical effect.

드라마,영화 영상촬영지의 관광기념품 활성화 방안에 관한 연구 : 국내 오픈세트장을 중심으로

강인지 ( In Ji Kang ),전성복 ( Sung Bok Jun ) 한국기초조형학회 2007 기초조형학연구 Vol.8 No.4