백혈병의 한의학적 질병 관점과 약물 기전 조사

강다혜,윤용선,조성훈,김준기,Kang, Dha-Hye,Yoon, Yong-Sun,Jho, Sung-Hoon,Kim, June-Ki 동국대학교 한의학연구소 2008 東國韓醫學硏究所論文集 Vol.11 No.-

The leukemia is caused by with abnormal changes of the hemotopoietic cell and in the various neoplasm group which occurs from lymph organization and the bone marrow occurs disrupts immigrates toward the blood of circumference and a hemotopoiesis and the arm discouragement royal tomb and is a disease which infiltrates with the organization. Western medical diagnosis and classification and presents eastern medicinal demonstration which is confronted in him about the leukemia, eastern medicinal diagnosis and treatment the clinical dissertation against precisely, saw and dissertation precisely tried about leukemia therapeutic effect of the herbal extract, last from conclusion like this dissertation precisely in the base which tries groped the direction of eastern medicinal treatment method research about the leukemia. Eastern medicine approach led about diagnosis and treatment of the leukemia and with leukemia treatment the medical herb which the eastern medicine possesses in development and room sacrifice an eastern medicine theory and the false eye presented the drug which is therapeutic possibility and they presented. The eastern medicine demonstration and therapeutic method is showing the therapeutic ratio which is effective about the leukemia. But according to the patient does a about prescription and therapeutic method differently and the room my composition is complicated and clinical day is consistent decides upon a reproducibility and a therapeutic ratio with difficult point of accumulation, with standardization of therapeutic method has the difficult point of supply. In treatment of the leukemia demonstrates a nature of a disease consequently with theory of eastern medicine and appropriately prescribes endeavors raises a therapeutic ratio and the medical herb and room proposal remedial value, under verifying reveals the clinical trial which is standardized leads and the medical herb and a room sacrifice and the verification and supply of effect and safety are necessary.

벌유충 분말 서플리먼트의 이명에 대한 임상적 연구

강다혜,오민지,김희택,Kang, Da-Hae,O, Min-Ji,Kim, Hee-Taek 대한한방안이비인후피부과학회 2012 한방안이비인후피부과학회지 Vol.25 No.2

Objectives : The primary purpose of present study is to evaluate the effect of a supplement of Bee Larva on tinnitus. the second is to comparatively evaluate safety of this supplement. Methods : Among those patients who visited Semyung Oriental Medical Center from January 11st, 2010 to February 20th, 2010, we screened 45 patients considered suitable for this study after some examinations and consent of the patients. they were devided into 2 groups. Group A took 5 tablets of this supplement everyday for 4 weeks, group B, placebo, in the same way. for 4 weeks, we checked changes in intensity, duration, extent of tinnitus on daily life and sleep and THI(Tinnitus Handicap Inventory) score. to evaluate safety of this supplement, adverse events, assessment of vital sign, hematologic examination were recorded. Result : Through 4 weeks of the clinical trial, we found that this supplement is effective on tinnitus and it improves intensity, duration and extent (its influence on daily life) of tinnitus, influence of tinnitus on sleep and THI score more effectively than the placebo drug. Also, in the assessment of the safety of the study the supplement of bee Larva and placebo drug, there were no adverse events and side effects over the average which need treatment for it. Moreover, there were not any abnormal findings in change of blood pressure and hematologic examination. Conclusion : According to this experiment, we confirmed that the supplement of bee Larva can be used effectively and safely on tinnitus.

스테로이드제제 부작용을 동반한 만성 족부 한포진 치험 1례

강다혜,김정현,임해원,김지영,권강,Kang, Da-Hae,Kim, Jung-Hyun,Lim, Hae-Won,Kim, Jee-Young,Kwon, Kang 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.1

Backgrounds : Pompholyx is a distinctive reaction pattern presenting as symmetric vesicular hand and foot dermatitis. Other than acute symptoms like itching and vesicles, chronic changes with scaling, fissure and pain may follow. As patients are treated by steroid for a long period, it tends to present side effects after quitting steroid treatment. Objectives : This study was carried out to investigate the effect of carbon arc lamp therapy and oriental medical therapy that venesection therapy, ointments and herbal medicine on chronic plantar pompholyx including steroids side effects. Methods : We treated one case of chronic plantar pompholyx which had continued about 10 years, including steroids side effects with venesection therapy, carbon arc lamp therapy, ointments and herbal medicine. To evaluate the results of this treatment, we categorized symptoms into six items which are vesicles, itching, fissures, pain, erosions and scales. Results : Except mild itching, vesicles and scales in a small area, all the symptoms were subsided. Conclusions : It is considered that various kinds of oriental medical therapy including carbon arc lamp therapy could replace steroid therapy which has many side effects.

리믹스 음악의 원곡 변형 방식에 관한 연구

강다혜(Da hye Kang),여운승(Woon Seung Yeo) 한국대중음악학회 2022 대중음악 Vol.- No.30

기존의 콘텐츠를 재구성하여 새로운 작품을 만드는 ‘리믹스’ 행위는 오늘날 문화 콘텐츠 제작의 거의 모든 분야에서 활발히 이루어지고 있다. 이러한 리믹스가 대중음악 분야에서 처음 시도되고 발전해왔음에도 불구하고, 다른 장르에 비해 정작 대중음악 분야에서는 이러한 원작 재구성의 원리에 대한 이론적인 논의가 부족한 것이 사실이다. 그리하여 본 논문은 리믹스 음악의 원곡 변형 방식을 분석한 결과를 정리하고, 이를 체계적으로 이해하기 위한 이론적 기반을 제시하고자 한다. 이를 위해 기존에 발표된 대중음악 리믹스 94곡을 선정하여 그 음악적 요소를 원곡과 비교하고, 리믹스 음악 창작의 기준으로 삼을 만한 대표적 유형을 파악했으며, 명쾌한 이론적 바탕을 마련하기 위해 문학 분야의 이론가 돌레젤이 제시한 온 원작 변형의 원리를 차용하는 가능성을 탐구하였다. 그 결과 리믹스 음악의 창작 유형은 1) 원곡의 반주(배경)는 그대로 보존하고 보컬 구성을 변형하는 ‘확장’과 2) 원곡의 보컬(등장인물)은 그대로 보존하고 반주를 새롭게 변형하는 ‘치환’의 두 가지 형태로 분류할 수 있었다. 이러한 발견을 바탕으로 파악된 리믹스 음악 창작의 핵심은 원곡의 보컬과 반주 중 하나를 그대로 보존하는 동시에 다른 요소를 완전히 변형하는 것이며, 그 결과 원곡이 지닌 아우라와 정체성을 유지하면서도 변형된 요소를 통해 원곡과의 차별성을 드러내는 것으로 정리할 수 있다. 이와 같이 본 논문에서 소개하는 연구는 음악이 아닌 분야에서 제시된 원작 변형 원리를 바탕으로 리믹스 음악의 창작 유형을 파악하고, 이를 통하여 기존 작품의 분석은 물론 신규 작품 창작을 위한 체계적인 전략을 제시할 수 있다는 점에서 의의가 있다. The act of remixing to create a new cultural product by reconstructing an existing one is being performed in almost all cultural content fields today. Even so, although the remix concept originated in the musical field, theoretical discussion concerning its reconstruction principles in popular music compared to other genres is lacking. This paper analyzes the methods of transforming original songs in remixing. Furthermore, it presents a theoretical basis for its systematic understanding. Ninety-four previously released popular music remixes were selected and compared with the original songs in terms of musical elements, thereby identifying representative types of reconstruction as a new standard for remix music creation. This comparison is then further studied to explore whether applying analytical methods of literary works allows for a deeper understanding of the musical remix process. As a result, musical remix types were categorized as either 1) an “expansion” process that preserves the original accompaniment (i.e., background) and transforms the vocal composition, or 2) a “transposition” process that creates a new accompaniment while preserving the original vocals (i.e., characters). Based on this finding, musical remixing could be described as preserving either the vocals or the accompaniment of the original song while completely transforming the other element. Thus, it maintains the original piece’s identity and aura but simultaneously reveals the difference. These results identify types of remixing popular music based on principles borrowed from a non-musical genre. Furthermore, they analyze existing types and suggest systematic strategies for creating new ones.

Anthony Browne의 〈겁쟁이 윌리〉의 세계관 분석

강다혜(Kang, Da Hye),현은자(Hyun, Eun Ja) 한국어린이문학교육학회 2022 어린이문학교육연구 Vol.23 No.4

섬유전극을 기반으로 한 라이프스타일 모니터링용 ECG-센싱의류의 프로토타입 연구

강다혜 ( Da Hye Kang ),조하경 ( Ha Kyung Cho ),송하영 ( Ha Young Song ),조현승 ( Hyun Seung Cho ),이주현 ( Joo Hyeon Lee ),이강휘 ( Kang Hwi Lee ),구수민 ( Su Min Koo ),이영재 ( Young Jae Lee ),이정환 ( Jeong Whan Lee ) 한국감성과학회 2008 감성과학 Vol.11 No.3

In order to develop “textile electrode-sensing clothing” which is a sort of smart clothing to measure electric activities of heart, we propose possible ways to develop textile electrode and design of sensing clothing, ultimately aiming to develop “ECG sensing clothing for lifestyle monitoring”. Conventional sensors for measuring typical electric activities of heart keep certain distance between measuring electrodes to measure signals for electric activities of heart, but these sensors often cause inappropriate factors (e.g. motional artifacts, inconvenience of use, etc) for monitoring natural cardiac activities in our daily life. In addition, most of textile electrodes have made it difficult to collect data due to high impedance and unstable contact between skin and electrodes. To overcome these questions, we minimized distance between electrodes and skin to maximize convenience of use. And in order to complement contact between skin electrodes, we modified textile electrode`s form and developed ways to design clothing. As a result, we could find out clinical significance by investigating possible associations of clinical electrocardiogram (ECG) with variation of distance between electrodes, and could also demonstrate clinically significant associations between textile electrode developed herein and clothing.

인체동작 모니터링을 위한 광섬유 기반 의류 소매형 동작센서 연구

강다혜 ( Da Hye Kang ),이영재 ( Young Jae Lee ),이정환 ( Jeong Whan Lee ),이주현 ( Joo Hyeon Lee ) 한국감성과학회 2011 감성과학 Vol.14 No.2

인체의 동작 센싱 방법에 대한 연구가 다양하게 진행되어 왔으나, 기존의 동작 센싱 방식에는 많은 한계점들이 있다. 기존의 동작 센싱 방식의 한계점을 보완하기 위한 일환의 노력으로, 이 논문에서는 비구속적인 동작 센싱이 가능한 광섬유 기반 의류 소매형 동작센서를 탐색적으로 연구하는데 목표를 두었다. 이 논문에서는 광섬유 기반의 의류 소매형 동작 센서를 고안하고, 이를 통하여 일상생활 중에 다양한 동작을 센싱하는 것이 가능한가에 대하여 탐색적 연구를 수행하였다. 또한 본 연구의 범위는 광섬유 기반 동작센서의 가능성 여부와 주요 요건을 탐색하는 것이며, 소매 패턴과 봉제 방식의 특성, 착용자의 체형 특성이 미친 영향은 연구 범위에서 제외되었다. 이러한 방식으로 의복에 적용 가능하도록 고안된 광섬유 기반 의류 소매형 동작센서는, 기존의 동작 센싱 시스템에 비하여 더욱 미세한 인체 동작 측정이 가능하며, 시간·공간의 제약 없이 저비용으로 인체 동작 측정이 가능하다는 장점을 갖는다. Although diverse researches on sensing method of human movement have been performed, there are still many limitations to the existing methods. As a part of supplementing the limitations to the existing motion sensing methods, this study aimed to execute an exploratory examination on a POF-based sleeve-shaped motion sensor for less restrictive sensing of human movement. In this study, a set of POF-based motion sensor, which was embedded in a sleeve-shaped platform was devised, and a set of exploratory experiments was performed on the possibility of sensing of human movement as diverse as in daily life, through this device. The scope of this research was limited to an exploration on the possibility and basic elements of POF-based sleeve-shaped motion sensor, while the influence of sleeve patterns, those of wearer`s somatotype, those of sewing method were not studied in this study. When compared to the pre-existing methods, the POF-based motion sensor platformed on sleeve in this study, which was purposively devised to be applied to the motion sensing clothing shows some beneficial characteristics: more sensitive measurement on human motion, low cost, no timely restriction in sensing, no request for gigantic apparatus and space for sensing.

농촌 그림책에 대한 도시와 농촌 아동의 반응 비교

강다혜 ( Da Hye Kang ),현은자 ( Eun Ja Hyun ) 한국어린이문학교육학회 2008 어린이문학교육연구 Vol.9 No.1

본 연구는 살아 온 환경과 경험, 배경 지식이 다른 도시 아동과 농촌 아동이 농촌 그림책을 보고 어떻게 반응하는지 살펴보는 것을 목적으로 하였다. 이를 위하여 농촌 그림책을 2권 선정하여 도시와 농촌 아동 간 농촌 그림책에 대한 반응에 차이가 있는지 살펴보았다. 본 연구는 초등학교 3학년의 도시 아동 40명과 농촌 아동 42명을 선정하여 농촌 그림책을 보고 농촌 그림책에 대해 1:1 면접을 진행하여 농촌 그림책의 공간적 배경에 대한 인식, 농촌 그림책의 시간적 배경에 대한 인식, 농촌 그림책과 자신이 사는 곳과의 비교, 현재 농촌과 농촌 그림책을 비교했을 때 어떠한 평가를 내리는지 살펴보았다. 본 연구의 결과는 아동이 살고 있는 지역에 따라 그림책에 대한 반응이 달라지며, 현재 농촌 그림책이 도시와 농촌 아동이 모두 공감하는 농촌으로 그려지고 있지 않다는 것을 보여준다. 농촌 그림책이 농촌에 가보거나 살아본 경험이 없는 도시 아동들이 농촌을 경험하고 농촌에 대한 이미지를 확립하는데 도움을 준다는 점을 고려할 때 본 연구의 결과는 앞으로 농촌 그림책의 제작에 시사점을 줄 것이다. This study examines how children who live in different environment respond to rural picture books. For this study, two rural picture books were selected and total 82 3rd grade elementary school children responded to the questionnaire prepared by the researcher. Among them, 42 lived in rural area and 40 in urban area. Study questions and their subcategories were as follows: 1. What are response of urban and rural children to rural picture books about spatial understanding? 2. What are the response of urban and rural children to rural picture books about time? 3. How do urban and rural children respond to rural picture books of rural picture books` setting? The results of this study were as follows: First, both urban and rural children recognized the spatial setting of the picture books as ``rural area``. With regard to the temporal setting, 60% of urban children thought of it as ``past`` and 40% of urban children thought ``present``. However, there were more children who thought the temporal setting as ``past`` among rural students. Second, urban children thought that the settings of rural picture books were similar to those of actual contemporary rural area, and they showed no significant difference in response between two picture books. However ruralchildren thought there are many differences between rural picture books and actual rural area, and they showed diverse responses to each picture book.

초등학생 독서교육을 위한 멀티미디어 전자책의 효용성 평가

김현희,강다혜,Kim, Hyun-Hee,Kang, Da-Hye 한국도서관정보학회 2008 한국도서관정보학회지 Vol.39 No.1

본 연구에서는 멀티미디어 전자책이 독서교육에 얼마나 유용하게 사용될 수 있는지 알아보기 위해서 전자책의 특성인 사운드와 인터페이스 기능을 갖고 있는 멀티미디어 전자책을 종이책과 비교하여 이 두 정보매체가 어린이의 독서 효과(정보 구성력, 정보 습득력 및 상상력)에 어떤 차이를 보이는지 조사하였다. 이외에 이 두 정보매체에 대한 어린이의 만족도 그리고 어린이의 개인적인 특성이 독서 효과에 어떤 영향을 미치는 지도 함께 살펴보았다. 실험 결과, 첫째, 독서 효과에서는 두 권의 책에서 각각 종이책의 정보 구성력과 정보 습득력이 전자책 보다 앞선 것으로 나타났다. 또한 다른 두 권의 책에서는 전자책의 정보 습득력이 종이책 보다 더 높게 나왔으나 전체 평균에서는 정보매체유형이 독서 효과에 통계적으로 유의미한 차이를 가져오지 못한 것으로 나타났다. 둘째, 초등학생의 종이책과 전자책에 대한 만족도는 종이책의 만족도가 더 높게 나타났으나 그 차이는 통계적으로 유의미하지 않았다. 셋째, 어린이의 독서량이 독서 효과의 세 가지 변인 중 정보 구성력과 정보 습득력에 긍정적인 영향을 미치는 것으로 나타났다. 끝으로 독서교육 또는 교과 관련 독서교육을 위한 멀티미디어 전자책 이용을 활성화시키기 위한 방안에 대해서 제안하였다. This study examines the differences in children's reading comprehension and satisfaction of storybooks according to a type of medium(paper and multimedia e-books). Six different storybooks were used and 85 children participated. Each child read a paper book and an e-book(both are different books). The study results showed that overall, the type of medium did not significantly affect the children's reading comprehension of all six storybooks: for two storybooks, some comprehension scores of paper books were higher than those of e-books, on the other hand, some comprehension scores of e-books were higher than those of paper books. Satisfaction scores of paper books are a little bit higher that those of e-books, although resulting in no statistically significant difference between two types. In addition, the study suggested that the amount of annual readings is positively related to improving children's composition ability and information acquisition ability. Finally, we proposed how to promote the use of e-books in the school library environments in terms of its usability and management policies.

정향 추출물 도포가 DNCB로 유발된 알레르기성 접촉 피부염에 미치는 영향

이경엽,강다혜,김희택,Lee, Kyung-Yeob,Kang, Da-Hae,Kim, Hee-Taek 대한한방안이비인후피부과학회 2013 한방안이비인후피부과학회지 Vol.26 No.4

Objectives : The purpose of this study is to investigate effects of Syzygium aromaticum (SAE) spread on the allergic contact dermatitis caused by 2,4-dinitro-chlorobezene (DNCB). Methods : Forty-two mice were divided into six groups ; normal, negative control (DNCB-treated), positive control (DNCB + 1% pimecrolimus), experimental group I, II and III. control and experimental groups were induced allergic contact dermatitis by DNCB. Experimental group I(DNCB + 0.2% SAE), II(DNCB + 1% SAE) and III(DNCB + 5% SAE) were spread SAE and positive control was spread the 1% pimecrolimus. In this study, effect of SAE on clinical aspects on the skin, histopathological change, the blood level of IgE, cytokines, histamine were investigated. In addition, effect of SAE on spleen $CD4^+/CD8^+$ T cell subset was investigated. Results : 1. In experimental group I, II and III, erythemas and edema were more reduced than negative control. 2. In experimental group I, II and III inflammatory edema and the numbers of infiltrated inflammatory cells were more reduced than negative control. 3. In experimental group I, II and III, clinical skin score was more reduced than negative control. 4. In experimental group II and III, the thickness of skin was statistically significant reduced than negative control. 5. In experimental group II and III, histamine release was statistically significant reduced than negative control in dose-dependantly. 6. In experimental group II and III, cytokines (IL-1${\beta}$, TNF-${\alpha}$, IL-4, IL-6, IL-10) were statistically significant reduced than negative control in dose-dependantly. 7. In experimental group I, II and III, the level of total IgE was statistically significant reduced than negative control in dose-dependantly. 8. In experimental group III, $CD4^+$ and $CD8^+$ T cells were statistically significant decreased similar to the positive control. Conclusions : According to above experiments, Syzygium aromaticum(SAE) was effective on allergic contact dermatitis.