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강규현(Kue Hyun Kang),이우석(Woo Seok Lee),윤성준(Seong Jun Yoon),이상훈(Sang Hoon Lee),허민(Min Hur),배도환(Do Hwan Bae),박형무(Hyoung Moo Park),김동호(Dong Ho Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.11
N/A Objectives : Our purpose was to evaluate the efficacy of pelviscopic classic intrafascial supracervical hysterectomy (CISH) & compare it with total abdominal hysterectomy (TAH). Methods : We analyzed retrospectively, the clinical data of 1126 patients admitted from January 1993 to December 1998, at 11 university or general hospitals in Korea, for CISH group and 363 patients admitted from January 1993 to December 1998, at Chung-Ang university hospitals, Seoul, Korea, for TAH group. These patients were operated on with the indication of benign uterine disease without cervical malignant lesion. The patients with malignant cervical lesion were excluded in this study. Results : ① The average age of CISH group was 42.2 (range 24-63) years old and TAH group was 46 (range 31-54) years old. ② The mean operative time was 150.7±49.9 (mean±SD, range 55-395) minutes in CISH group and 133.8±35 (mean±SD, range 65-350) minutes in TAH group. The mean estimated blood loss was 206±183.6 (mean±SD, range 20-2000) ml in CISH group and 596±452.3 (mean±SD, range 100-6500) ml in TAH group. The mean hemoglobin change was 1.52±0.98 (mean±SD, range 0-7) g/dL in CISH group and 3.03±1.47 (mean±SD, range 0.2-8.4) g/dL in TAH group. The mean time in hospital was 6.3±1.43 (mean±SD, range 3-18) days in CISH group and 11.0±4.08 (mean±SD, range 7-37) days in TAH group. ③ Overall complications occured at 5.3% in CISH group and 9.1% in TAH group. ④ Pathologic findings of cervix were benign in 1121 patients (99.6%) and severe dysplasia or carcinoma in situ in 5 patients (0.4%) among CISH groups. In TAH groups, 351 patients (96.7%) had benign cervical lesion and 12 patients (3.3%) had more than moderate dysplasia or carcinoma in situ. In both groups, no invasive cervical cancer was found and the transformation zone of the cervix was included within the resection margin of the cervix in all cases. Conclusion : The pelviscopic CISH group has less operative blood loss, less postoperative hemoglobin change, shorter hospital stay and less operative complication than TAH group. Pelviscopic CISH is truly a minimally invasive and organ-preserving surgery and coring out the cervix with the calibrated uterine resection tool may prevent the development of cervical cancer. Therefore, we believe that pelviscopic CISH is preferred in cases of benign uterine diseases, because it lowers operative complications and it may have several benefits compared with total hysterectomy, especially, in women with no pathologic lesion of the cervix.
폐경기 호르몬 보충요법에서 골밀도 변화에 대한 골표지자의 예측능력
박형무(Hyoung Moo Park),김태철(Tae cheol Kim),강규현(Kue Hyun Kang),윤성준(Sung Jun Yoon),허민(Min Hur) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.2
목적: 폐경기 때 호르몬 보충 요법을 단독으로 사용한 경우와 비타민 D를 같이 복용한 경우, 단기간 (3개월)에 골표지자의 변화를 이용하여 장기간(1년)의 골밀도 변화를 예측가능한 지를 알아보고자 하였다. 연구 방법: 호르몬 보충요법만 사용한 41명과 활성 비타민 D인 칼시트리올(0.25ug/day)을 병합하여 사용한 23명, 총 64명의 자연 폐경된 환자를 대상으로 처음 내원시 혈중 osteocalcin과 요중 deoxypyridinoline, 그리고 요추부 골밀도를 측정하고 3개월 뒤 골표지자인 OC와 Dpd를 다시 측정하고 그리고 1년 뒤 요추부 골밀도를 다시 측정하여 단기간의 골표지자의 변화와 장기간의 골밀도의 변화 사이에 어떤 상관 관계와 연관성이 있는 지 알아보았다. 결과: 1.호르몬 보충 요법 후 3개월 뒤 혈중 OC와 Dpd는 각각 20.9%와 30.1%의 감소를 보였고 1년 뒤 골밀도는 3.8% 증가를 보였다. 2. 3개월 뒤에 측정한 요중 Dpd가 감소한 58명의 환자중 49명(84.5%)이 골밀도에서 증가를 보인 반면,혈중 OC가 감소한 49명 중에서는 40명(81.6%)이 골밀도의 증가를 보였다. 3. 골밀도가 증가한 그룹과 감소한 그룹간의 골표지자의 변화를 비교한 결과 증가한 그룹에서는 혈중 OC와 요중 Dpd가 18.1%, 32.6% 감소하였고 골밀도가 감소한 그룹에서는 9.2%,20.4% 감소하여 두 그룹간에 통계적으로 유의한 차이가 있게 골밀도가 증가한 그룹에서 더욱더 골표지자의 감소가 있었다. 4. 골밀도의 변화와 골표지자의 변화 사이에 상관관계는 혈중 OC가 r값 -0.174(p>0.05), 요중 Dpd가 r값 -0.091(p>0.05)로 의미 없게 나타났으나 반면,비타민 D를 투여하지 않은 호르몬 단독 요법을 사용한 경우에 요중 Dpd의 변화와 골밀도의 변화 사이에는 r값 -0.376(p<0.05)으로 역상관 관계를 보여주었다. 결론: 비타민 D를 투여하지 않은 호르몬 단독 요법을 한 경우에서만 요중 Dpd 변화와 골밀도 변화 사이에 어느 정도 역 상관관계를 보일 뿐 전반적으로 골표지자의 변화와 골밀도의 변화 사이에는 상관 관계가 없는 것으로 나타나 단기간의 골표지자의 변화로서 장기간의 골밀도의 변화를 미리 예측 할 수가 없었다. Objective: To estimate the long-term skeletal responses to hormone replacement therapy(HRT) with or without active vitamin D(VD) by using short-term changes of bone markers in postmenopausal women (PMW). Methods: Biochemical markers of bone formation(osteocalcin,OC) and (&) resorption(deoxypyridinoline, Dpd ) at 3 months & lumbar bone mineral density(BMD) at 1 year were measured in 64 natural PMW taking HRT(n=41) & HRT with calcitriol 0.25 μg/day(n=23). The correlation of percent changes of bone markers after 3 months of Tx with those in lumbar BMD after 1 year was evaluated. Results: 1. serum-OC & urine-Dpd showed decrease of 20.9% & 30.1% at 3months respectively & BMD increase of 3.8% after 1 year of Tx. 2. Among 58 PMW with decreased u-Dpd change, 49 (84.5%) revealed increase in BMD, while 40 (81.6%) among 49 PMW with decreased serum-OC change showed increased BMD. 3. Bone gainers showed significant decrease in changes of serum-OC(18.1% vs 9.2% p<0.05) & urine-Dpd(32.6% vs 20.4%, p<0.05) compared with those of bone losers. 4. No correlations of change of serum-OC (r=-0.174 p>0.05) & urine-Dpd (r=-0.091 p>0.05) at 3month with BMD changes at 1year were seen in total PMW, but urine-Dpd changes in HRT without active VD group revealed significantly inverse correlation(r=-0.376 p<0.05). Conclusion: Short-term changes of bone markers did not precisely predict the long-term changes of BMD in total PMW except urine- Dpd in HRT without active VD.
최규형(Choi Kyu-Hyoung),정의진(Jeong Ei-Jin),강규현(Kang Gyu-Hyun) 한국철도학회 1999 한국철도학회 학술발표대회논문집 Vol.- No.-
The main purpose of this study is to develope a Simulator for Central Traffic Controller(CTC) which can check the operating status of CTC and support the maintenance procedure. The simulator supervise the CTC processor units and the data transmission between the CTC modules and the railway station equipments to define the validity of system functions and notify whether the eqipments are good or not. With the help of the simulator we could detect the error of CTC equipments easily, repair the faults efficiently, and improve the reliability of CTC system.
이선경 ( Seon Kyoung Lee ),노현경 ( Hyon Kyung Rho ),강규현 ( Kue Hyun Kang ),지정석 ( Jung Suk Jee ),김상용 ( Sang Yong Kim ),조태일 ( Tae Il Joe ),윤귀옥 ( Gui Okh Yoon ) 대한주산의학회 2007 Perinatology Vol.18 No.3
Heterotopic pregnancy with coexistiong intrauterine and extrauterine pregnancy, is a rare event in natural pregnancy. However, in recent years, the increase in the incidence of pelvic inflammatory disease and use of assisted reproductive technology had led to an increase in the frequency of heterotopic pregnancy. When the diagnosis of heterotopic pregnancy is delayed, maternal mortality and morbidity may be increased, and unwanted loss of intrauterine pregnancy may occur. Therefore, the early diagnosis of heterotopic pregnancy is clinically important, and clinicians have to consider the possibility of heterotopic pregnancy and conduct careful and thorough evaluation if suspected. We experienced a case of heterotopic pregnancy in a woman in the absence of the known risk factors. She underwent underwent spontaneous abortion of intrauterine pregnancy at postoperative 4th day, after laparoscopic salpingectomy for left tubal pregnancy. We report this case with brief review of literature.