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Intra-familial Infection due to Trichophyton tonsurans in Korean General Population
김호윤,이원주,김상림,이석종,김도원,전재복 대한의진균학회 2014 대한의진균학회지 Vol.19 No.4
Trichophyton (T.) tonsurans is a common anthropophilic species, which causes tinea capitis and tineacorporis particularily in Europe and America, but has not been prevalent in Korea. One case withmycoses infection of the scalp and the other with tinea corporis due to T. tonsurans were observed inKorean general population. We confirmed T. tonsurans infection on the basis of the direct microscopicexamination and culture from scales and infected hairs of skin lesions. Systemic itraconazole andterbinafine therapy with topical ketoconazole cream led to clinical and mycological recovery in ourcases. Infection of T. tonsurans appears to have spread gradually among the general population inKorea. Therefore, athletic and medical associations should make constant observation and take closeconsideration about T. tonsurans infection.
김호윤,한군희,신승수 중소기업융합학회 2021 융합정보논문지 Vol.11 No.11
인터넷이 발달하면서 온라인에서 나를 증명하는 사용자 인증기술은 고도화되고 있다. 기존 ID 방식은 서비 스 제공자가 개인정보를 관리하며 보안이 취약할 경우 개인정보 유출의 위협이 있고, 정보 주체가 서비스 제공자 에게 있다. 본 연구에서는 온라인 신분 확인 기술이 발전함에 따라 중앙집중 형식에서 오는 개인정보 유출 위협을 낮추고 사용자 주권 강화를 위한 DID 기반 본인 인증 모델을 제안한다. 제안 모델은 발행기관으로부터 발급받은 VC를 통해 사용자가 직접 개인정보를 관리하고 정보 주제가 사용자에게 있어 주권을 강화할 수 있다. 연구 방법으 로는 분산원장 기술을 기반으로 한 탈중앙화 신원증명 방법을 이용하여 보안성과 무결성을 보장하는 본인 인증 모델을 제시하고, 공격방식에 대한 보안성을 분석한다. 공개키 암호 알고리즘을 사용하는 DID Auth를 통해 인증 하여 스니핑, 중간자공격 등으로부터 안전하며 제안 모델은 실물 신분증을 대체할 수 있다. With the development of the Internet, user authentication technology that proves me online is improving. Existing ID methods pose a threat of personal information leakage if the service provider manages personal information and security is weak, and the information subject is to the service provider. In this study, as online identification technology develops, we propose a DID-based self-authentication model to prevent the threat of leakage of personal information from a centralized format and strengthen sovereignty. The proposed model allows users to directly manage personal information and strengthen their sovereignty over information topics through VC issued by the issuing agency. As a research method, a self-authentication model that guarantees security and integrity is presented using a decentralized identifier method based on distributed ledger technology, and the security of the attack method is analyzed. Because it authenticates through DID Auth using public key encryption algorithms, it is safe from sniffing, man in the middle attack, and the proposed model can replace real identity card.
Device Wafer의 종점 전후에 있어서 광역평탄화 특성에 관한 연구
정해도,김호윤 釜山大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.51 No.-
화학적 기계적 폴리싱(CMP)은 반도체 제조에서 다층구조의 평탄화에 널리 이용되고 있다. 그러나, 패턴의 형상·물질 차이, 여러 가지 가공 변수와 아직 확립되지 않은 실제 가공 모델링 등으로 인하여 완전한 평탄화를 얻기는 쉽지 않다. 본 논문에서는 에치 백 방법 대신 메탈(텅스텐) 폴리싱에 따르는 절연산화막의 평탄화를 실현하였다. CMP 가공동안의 패턴 형상 평가는 AFM을 사용하였다. AFM 평가는 다른 일반적인 평탄도 측정에 비해서 미소 측정에 상당히 효과적이었다. 더불어 평탄화 특성 분석과 CMP 모델링 확립에 크게 기여할 것이다. Chemical mechanical polishing (CMP) has become widely accepted for the planarization of multi-interconnect structures in semiconductor manufacturing. However, perfect planarization is not so easily achieved because it depends on the pattern sensitivity, the large number of controllable process parameters, and the absence of a reliable process model, etc. In this paper, we realized-the planarization of deposited oxide layers followed by metal (W) polishing as a replacement for tungsten etch-back process for via formation. Atomic force microscope (AFM) is used for the evaluation of pattern topography during CMP. As a result, AFM evaluation is very attractive compared to conventional methods for the measurement of planarity. Moreover, it will contribute to analyze planarization characteristics and establish CMP model.
제품화된 무방부제 힐론 점안제가 각막상피세포에 미치는 영향
김호윤,박영민,이종수,Ho Yun Kim,Young Min Park,Jong Soo Lee 대한안과학회 2014 대한안과학회지 Vol.55 No.11
Purpose: To investigate the biologic effects of preservative-free artificial tear drops on cultured human corneal epithelial cells in vitro. Methods: The effects of preservative-free artificial tear drops (sodium hyaluronate 0.1% (Kynex<SUP>Ⓡ, Alcon, Seoul, Korea), sodium hyaluronate 0.18% (Kynex2<SUP>Ⓡ, Alcon, Seoul, Korea), and sodium hyaluronate 0.3% (Hyaluni eye drops 0.3%<SUP>Ⓡ, Taejoon, Seoul, Korea)) on human corneal epithelial cells were evaluated. Cellular proliferation was determined using MTT (3- (4,5-dimethylthiazol- 2yl)-2,5-diphenyl-2H-tetrazolium bromide) and Ki-67 assays. Cellular migration was determined using CD44 and scratch wound assays. Cell damage was determined using the lactate dehydrogenase (LDH) assay and cellular morphologies using electronic microscopy and inverted microscopy. Results: Proliferation of corneal epithelial cells, as determined by the MTT and Ki-67 assays, was not significantly different between the different eye drops (<EM>p</EM> > 0.05). The measured value of cellular migration after exposure of the sodium hyaluronate 0.3%, as determined by mean CD44 percentage and scratch wound assay, was higher than that of the sodium hyaluronate 0.1% and sodium hyaluronate 0.18%, but the CD44 value was not significantly different (<EM>p</EM> > 0.05). The LDH titer tended to increase as the concentration of sodium hyaluronate increased (<EM>p</EM> > 0.05), but influence on cytoplasm, as determined by electronic microscopy, was not different. Conclusions: Among 3 preservative-free artificial tear drops, sodium hyaluronate 0.3% demonstrated increased migration of corneal epithelial cells. As the concentration of sodium hyaluronate in eye drops increased, the corneal cytotoxicity of corneal epithelial cells also increased. However, there was no significant difference among the 3 tear drops. J Korean Ophthalmol Soc 2014;55(11):1698-1705