에스트로겐과 활성형 비타민 D의 병합투여가 요추 골밀도에 미치는 영향

조석신,이재억,유중배,황윤영,조수현,문형 대한폐경학회 1996 대한폐경학회지 Vol.2 No.1

Administration of estrogen or vitamin D has been shown to increase bone mineral density in postmenopausal women. To evaluate any added beneficial effects of estrogen combined with vitamine D, 101 postmenopausal attending menopause clinic were allocated into two treatment group; group l,estrogen + progestin(n=72); group 2,estrogen + progestin + 1a-hydroxyvitamin D3 0.5ug/day(n=29). After 1 year of treatment, spinal bone mineral density(BMD) were increased 3.3% in all women. The percent increament of spinal BMD is higher in group 2 than in group 1(244±6.7 vs 5.7±9.8, p$lt; 0.05) and higher in women with osteopenia than normal BMD before treatment(3.4±2.4 vs 8.4±11.2, p$lt;0.05).The percent increasment of spinal BMD correlated with age(group 1; r=0.27, p=0.02, group 2;r=0.41, p=0.02) and menopausal duration in group 2(r=0.45, p=0.01). From the above results, it might be suggested that conbined therapy is more effective in postmenopausal women with osteopenia.

한국인 정상만삭산모와 신생아의 P.B.I.치

조석신(SS Cho) 대한산부인과학회 1967 Obstetrics & Gynecology Science Vol.10 No.1

Little is Known about the protein-bound-iodine concentration of the Korean Mothers and their infants in normal full-term pregnancies. P.B.I. was taken by moriyaki-Yoshikawa`s modified method in 35 cases of normal full-term paturients and their infants immediately after delivery. The results were summarized as follows: 1) The mean value of PBI content in full-term paturients was 8.2+1.34 Υ/dl. and 7.0+1.14Υ/dl.in their infants.

핵의학적 검사로 관찰된 기정맥계

조석신,강종명 대한핵의학회 1985 핵의학 분자영상 Vol.19 No.2

Azygos system, one of the main collateral vessels which communicates superior vena cava with inferior vena cava, is well visualized by X-ray angiography. This systern is rarely demonstrated by radioisotope study. We report a case whose azygos system was shown during (99m)^Tc-DTPA renal scanning.

방사선이 자궁경암세포 염색체에 미치는 형태학적 변화

조석신(SS Cho) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.6

The effect of radiation on the chromosomes of the cancer cell of uterine cervical squamous cell carcinoma was investigated in this study with the use of primary tissue culture technic. The obstained results were as follows; 1) The samples for the initial tissue culture procedure were devided into non-irradiated group, 100 Rad irradiated group and 400 Rad irradiated group. Each group consisted of 35cases. Tissue culture was successful in 9 cases of the non-irradiated group, 5 cases of 200 Rad irradiated group and 3 cases of 400 Rad irradiated group. 2) The numerical aberrations of the chromosomes observed in the 414 cells of the non-irradiated group and the 282 cells of the irradiated group were within the range from haploid to tetraploid. Stem-line of hyperdiploid could be noticeable but no remarkable difference in the number of chromosome could be found. 3) The breakage rate as a criterion for the incidence of chromosomal aberration was 14.24% in the non-irradiated group and 29.43% in the irradiated group. There was significant difference in the incidence of chromsomal aberration.

紙狀兒를 同伴한 雙胎妊娠

趙石臣,金明子,金善元,金聖心 大韓産婦人科學會 1968 大韓産婦人科學會雜誌 Vol.11 No.8

지상아를 동반한 쌍태임신

조석신(SS Cho),김명자(MJ Kim),김선원(SO Gim),김성심(SS Kim) 대한산부인과학회 1968 Obstetrics & Gynecology Science Vol.11 No.8

Fetus papyraceus is a rare complication of multiple pregnancy. Recently, we had a chance to study a case of fetus papyraceus in monochorial twin pregnancy at the Dept. of Obstetrics and Gynecology, Seoul National University Hospital. A Case of fetus papyraceus is presented with brief review of the literatures.

二重 流出路를 가진 左心室 : 部分的 大脈管轉位症을 同伴한 先天性 心畸形의 1剖檢例 An Autopsy case Report of a Congenital Heart Anomaly with a Partial Transposition of Great Vessels

趙石臣,金明子,金善元,鄭佐九,池堤根,李尙國 大韓産婦人科學會 1968 大韓産婦人科學會雜誌 Vol.11 No.1

경구피임제 "OVRAL"의 임상연구

조석신(SS Cho),최연동(RD Choi),강길원(KW Kang),김승욱(SW Kim) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.3

Clinical study with Ovral, containing 0.5mg of norgestrel and 0.05mg ethynyl estradiol, has been performed with a grant from Wyeth Laboratories Philadelphia. Two-hundred and twenty-eight married fertile women have been selected for contraceptive treatment with Ovral those who had seeked contraceptive advice at the Family Planning Clinic, Deoartment of Obstetrocs and Gynecology of Seoul National Univeersity Hospital. They have received the treatment with Ovral for 21 days each cycle and a total of 1,112 cycles has been accumulated with these 228 wimen. Individual cycles varied from one to 11 cycles. Continuation rates by the 3rd and 6th cycle were 70.2 and 39.9 per cent respectively,and only 3.9 per cent of the total have continued the use of pills up to 11th cycle. Most of the side effects have developed during the first 3 cycles of use. These were mild and transi- tory in nature. Most frequently encountered side effects were indigestion, nausea & vomiting and loss of appetive in the order of frequency. Poor digestion occurred in 2.7 per cent of the total cycles; and nausea vomiting in 2.25 per cent. Spotting occured in 0.3per cent of the total cycles; break-through bleeding in 0.2 per cent; head- ache and dizziness in 0.72 and 0.54 per cent respectively. Chloasma have developed in 1.5 per cent of the total cycles, which is rather higher than those obtained from the othe studies. Change in body weight have not been recognized in 44.0 per cent and changes of + 1kg in weight have been noted in another 34.2 per cent of the total cases. Not a single case of pregnancy has been noted.

양수내의 Testosteron 대 Follicle Stimulating Hormone 비율에 관한 연구

조석신 대한핵의학회 1982 핵의학 분자영상 Vol.16 No.2

To evaluate fetal sex-hormonal status before delivery, testosterone and follicle stimulating hormone(FSH)levels were measured in 64 amniotic fluid samples at midgestation by radioimmunoassay method. The mean concentration of testosterone in amniotic fluid of 37 cases carrying male fetus was 90.7pg/ml and 27 cases carrying female fetus was 62.3pg/ml. The mean amniotic fluid FSH concentration of male fetus was 1.15 mIU/ml and of female fetus was 11.98 mIU/ml. The amniotic fluid testoserone and FSH' concentrations had statistical difference between male and female fetuses. The ratio of testosterone over FSH in the amniotic fluid was 231.2 in female, 9.8 in female respetively and very significant difference was noticed. The levels of testosterone/FSH greater than 25 were found over 92% of male fetus and lesser than 25 were found over 92% female fetus. Measurement of testosterone and FSH especially testosterone/FSH ratio in amniotic fluid in midgestation may be an adjunct to other method of fetal sex determination.

임산부의 임상통계적 관찰

조석신(SS Cho) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.11

A clinical and statistical study on 2.028 women and their 1,880 newborn babies has been carried out with specific reference to groups of women who had reeived and not received antenatal cares. These 2,028 women had been admitted and delivered their babies at the Seoul National University Hospital during the period from April 1,1966 to March 31, 1968. Among the observed pregnant women 552 received regular antenatal care at the Out Patient Clinic, Department of Obstetrics and Gynecology, Seoul National Hopital and the rest 1,476 did not. The above-mentione 1,880 now born infants are sum of 547 infants of the ante- natallu cared group and 1,33 infants of the non-cared group. The following conclusion could be obtained by deviding the patients into primipara and multipara group and the antenatally cared and non-cared group respecively. The average number of admitted pregnant women was 84.2 per month and only 27,2% of them had received regular antenatal care. The obstetrical history,excluding the pregnancy at the time of admission, reveaked that average frequency of their previous pregnancy was 1.60. 759 primipara occupied 37.7% of the observed pregnant women and the rest 62.3% (1,269) multipara. In the observed patients 93.2% (1,889) never experienced premature delivery. No history of abortion was noted in 73.7% (1,491) of the total pregnant women. The average frequency of abortion wxperienced by the patients was 0.48 and there was some difference of the frequency between the antenatally cared group and non-cared group, that was 0.28 in the cared group and 0.55 in the non-cared group. The average number of living babies was and 52.1% (1,055) of the observed patients had no baby. The average duration of hospitalization in the admitted patients was 4.38 days. Showing the relativly short hospitalization in the antenatally cared group, average duration in the cared group was 3.98 days and 4.71 days in the non-cared group. The average homoglobin value at the time of delivery was 10.5gm/d (10.73gm/d in the cared group and 10.47gm/d in the non-caredgroup), and the hematocrit value was 33.4% (33.38% in the cared group and 32.59% in the non-cared group). The normal delivery was possible in 75.7% of the observed pregnant women (82.7% of the cared group and 72.8% of the non-cared group). Cestrean section was performed in 8.7% of the patients(4.6% of cared group and 10.4% of non-cared group). The manual expulsion of the placenta was done in 3.2% of the cared group and 10.2% of the non-cared group. Average amount of blood-loss during delivery was 304m (283m in the cared group and 310m in the non-caredngroup). Obstetrical complications were observed in 89 patients (16.5%) of the 538 antenatally cared patients and the total frequency of the complications was 149 times. In the non-cared group with total number of 1,312, 31.4% showed the obstetrical complication and their total freque- ncy was 699 times. The perinatal mortality was 70.81(27.4 in cared group and 83.42 in the non-cared group). The secondary sex ratio of the newborn infants was 106:100 and the average body weight of the newborn infants was 3.345gm (3.354gm in male and 3.335gm in female).