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송홍석,허정욱 啓明大學校 醫科大學 1985 계명의대학술지 Vol.4 No.2
저자들은 1972년 1월부터 1984년 12월 사이에 본원에 내원한 치료병력이 없는 Waldeyer 편도환을 침범한 림프종환자 24예를 분석검토하여 다음과 같은 결과를 얻었다. 연령은 14세에서 82세까지로 평균 48.8세였으며 남녀비는 1.7:1로 남자에서 많았다. 초진시의 증상은 경부종양이 14예(58.3%)로 가장 많았으며 인후통 12예(50%) 연하통 6예(25%) 연하곤란 5예(20.8%) 목쉼 및 비폐색이 각기 4예(16.7%)였다. 초진시의 이학적소견은 림프전종대가 19예(79.2%)로 경부 액와부 서혜부 쇄골상와림프길 순으로 빈번하였으며, Waldeyer 편도환의 침범은 비호지킨 림프종의 11.1% 호지킨병의 4.7%에서 동반되었으며 부위별로는 편도가 18예(75%) 비인두가 6예(25%) 설기저부가 1예(4.2%)였다. 조직학적분류를 보면 조직구형이 20예(83.3%)로 대부분을 차지하였으며, diffuse poorly-differentiated lymphocytic형 2예, nodular poorly-differentiated lymphocytic형 1예 그리고 호지킨병이 1예였다. 병기별로는 stageⅠ,Ⅱ가 15예(62.5%)로 모두 조직구형이었으며 stageⅢ,Ⅳ가 9예(37.5%)였고 B형은 4예(16.7%)로 진행된 병기에서 동반율이 높았다. 치료는 stageⅠ,Ⅱ 9예는 방사선요법, stageⅢ,Ⅳ 6예는 다제병합화학요법 그리고 stageⅡ,Ⅲ,Ⅳ 각 1예는 병용치료를 시행하였으며 이 중 stageⅠ,Ⅱ의 6예(60%)외 stageⅢ,Ⅳ의 4예(50%)에서 부분적관해 이상의 반응을 나타내었다. A retrospective review is presented of 24 previously untreated patients with lymphoma of Walde-yer's ring(WR) between January 1972 through December 1984 at the Keimyung University. The incidence of WR involvement of non-Hodgkin's lymphoma was 11.1% and of Hodgkin's disease was 4.7%. The mean age was 48.8 years, with a male to female ratio of 1.7 : 1.0. On admission, neck mass was the most frequent symptom in 14 cases(58.3%) and sore throat, odyno-phagia, dysphagia, hoarseness and nasal stuffiness were commonly presented. The anatomical distribution of the growth within WR was as follow: tonsil, 75.0%; nasopharynx, 25.0%; base of tongue, 4.2%. Histiocytic architecture predominated (83.3%) and local-regional involvement (stage Ⅰand Ⅱ) occurred in 75% with this morphology. Other histologic pattern was 2 cases of diffuse poorly-differentiated lymphocytic, 1 case of nodular poorly-differentiated lymphocytic lymphoma and 1 case of Hodgkin's disease with all in advanced stage (stage Ⅲ and Ⅳ). All ofthe local-regional disease were treated by irradiation and 1 patient were treated in addition with combination chemotherapy. Advanced disease were treated initially by combination chemotherapy. Response rate (complete response plus partial response) of stage Ⅰ and Ⅱ was 60% and stage Ⅲ and Ⅳ was 50%.
허정욱,이춘우,백기엽 충북대학교 한국과학재단 지정 첨단원예기술개발 연구센터 2002 연구보고서 Vol.6 No.-
이상으로, 발광다이오드를 광원으로 하는 자연광 이용형 보광장치는 광강도가 매우 낮은 장마기와 같은 광환경이 불량한 시기에 적절히 이용하므로서 식물체의 엽면적 증대, 왁스와 같은 특정성분 증량 및 분지등의 생장이나 형태형성에 효과적인 영향을 미칠 수 있는 실용적인 보광시스템으로서의 이용가능성이 검토되었다. 또한, 두종류의 관엽식물에 있어서 약간의 생장 및 형태형성에 있어 상이한 결과를 나타내었으나, 보광을 하지 않은 자연광구에 비하여 저광강도의 발광다이오드를 보광 조사하므로서 두 관엽식물의 생장이나 이상적인 형태형성이 이루어지는 것을 알 수 있었다. 금후, 관엽식물 뿐만 아니라 다른 식물 종을 대상으로 발광다이오드를 광원으로 하는 자연광 이용형 광조사 시스템을 광원으로 하는 연구가 활발히 진 The effect of supplemental lighting providing by Light-Emitting Diodes at daytime on growth of two ornamental plants was investigated. 'Camella' Dieffenbachia amoena and 'Melany' Ficus pumila were grown under different supplemental lights of blue, red, or blue plus red for 50days. The supplemental lights with 30㎛ol m-2 s-1 in photosynthetic photon flux were established in greenhouse which controlled at 27.5℃ air temperature and 75% relative humidity in average from 15th June to 4th August. Fresh weight of 'Camella' was the greatest in the supplemental treatment of blue plus red light, although there was no significant difference in dry weight. Higher plant height was shown in the mixture light of blue plus red and in control of natural lighting. The fresh and dry weights of 'Melany' were significantly higher in the mixture treatment than in control without any supplemental light. Number of unfolded leaves of 'Camella' and 'Melany' was increased in the mixture treatment. Net photosynthetic rate (NPR) of 'Camella' was the greatest in the mixturelight and control, and the red alone and mixture light treatments gave the highest NPR in 'Melany'. Wax content per leaf of blue plus red treatment in 'Melany' was significantly higher than in control.
Current Status of “Watch-and-Wait” Rectal Cancer Treatment in Asia-Pacific Countries
허정욱,Kotaro Maeda,Zheng Liu,Xishan Wang,April Camilla Roslani,이우용 대한대장항문학회 2020 Annals of Coloproctolgy Vol.36 No.2
Purpose: Current acceptance of the watch-and-wait (W&W) approach by surgeons in Asia-Pacific countries is unknown. An international survey was performed to determine status of the W&W approach on behalf of the Asia-Pacific Federation of Coloproctology (APFCP). Methods: Surgeons in the APFCP completed an Institutional Review Board-approved anonymous e-survey and/or printed letters (for China) containing 19 questions regarding nonsurgical close observation in patients who achieved clinical complete response (cCR) to neoadjuvant chemoradiotherapy (nCRT). Results: Of the 417 responses, 80.8% (n = 337) supported the W&W approach and 65.5% (n = 273) treated patients who achieved cCR after nCRT. Importantly, 78% of participants (n = 326) preferred a selective W&W approach in patients with old age and medical comorbidities who achieved cCR. In regard to restaging methods after nCRT, the majority of respondents based their decision to use W&W on a combination of magnetic resonance imaging results (94.5%, n = 394) with other test results. For interval between nCRT completion and tumor response assessment, most participants used 8 weeks (n = 154, 36.9%), followed by 6 weeks (n = 127, 30.5%) and 4 weeks (n = 102, 24.5%). In response to the question of how often responders followed-up after W&W, the predominant period was every 3 months (209 participants, 50.1%) followed by every 2 months (75 participants, 18.0%). If local regrowth was found during follow-up, most participants (79.9%, n = 333) recommended radical surgery as an initial management. Conclusion: The W&W approach is supported by 80% of Asia-Pacific surgeons and is practiced at 65%, although heterogeneous hospital or society protocols are also observed. These results inform oncologists of future clinical study participation.