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신기원,김신후,김준환,황성돈,강주찬 한국수산과학회 2016 Fisheries and Aquatic Sciences Vol.19 No.4
Rockfish, Sebastes schlegelii (mean length 14.53 ± 1.14 cm and mean weight 38.36 ± 3.45 g), were exposed for 4 weeks with the different levels of ammonia in the concentrations of 0, 0.1, 0.5, and 1.0 mg/L at 19 and 24 °C. The indicators of growth performance such as daily length gain, daily weight gain, condition factor, and hematosomatic index were significantly reduced by the ammonia exposure and high temperature. The ammonia exposure induced a significant decrease in hematological parameters, such as red blood cell (RBC) count, white blood cell (WBC) count, hemoglobin (Hb), and hematocrit (Ht), whose trend was more remarkable at 24 °C. Mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) were also notably decreased by the ammonia exposure. Blood ammonia concentration was considerably increased by the ammonia concentration exposure. In the serum components, the glucose, glutamic oxalate transaminase (GOT), and glutamic pyruvate transaminase (GPT) were substantially increased by the ammonia exposure, whereas total protein was significantly decreased. But, the calcium and magnesium were not considerably changed.
신기원,박영미,김태현,이안복,박하영,윤혜경,허영진,백진욱,이유진 대한영상의학회 2020 대한영상의학회지 Vol.81 No.2
Herein, we report a case of synchronous bilateral triple negative invasive ductal breast carcinoma in a patient with discrepant pathologic response to neoadjuvant chemotherapy. Right and left breast cancer stages at the initial diagnosis were T1cN0M0 and T4dN3aM0, respectively. The patient was identified as a BRCA1 mutation carrier and treated with four cycles of adriamycin and cyclophosphamide, followed by four cycles of docetaxel. Bilateral breast cancer stages decreased with the first regimen. However, the bilateral breast cancers showed discrepant responses to chemotherapy with docetaxel. The right breast cancer showed a continuous tumor volume reduction while the left breast cancer showed marked progression. Finally, the tumor size was 0.3 cm and 12 cm in the right and left mastectomy specimens, respectively. As bilateral breast cancers of the same subtype may show discrepant responses to neoadjuvant chemotherapy, close monitoring and follow-up imaging are required to avoid delayed surgery.
신기원,임경업,윤애선,권혁철 한국지능정보시스템학회 2010 한국지능정보시스템학회 학술대회논문집 Vol.2010 No.11월
음악 추천 시스템에서는 음악에 대한 감정 분석 연구가 필요하다. 본 논문에서는 기구축 된 감정 온톨로지를 활용하여 가사 기반의 음악 감정 추출 방법에 대하여 연구하였다. 기구축 된 범용적 감정 온톨로지를 활용하여 감정 라이브러리의 선택적으로 사용하고 사용방법을 2 가지로 구분하였다. 그리고 감정 추출의 정확도 향상을 위하여 한국어의 통사적 특징을 분석하여 만든 4 가지 통사적 규칙을 적용한다. 연구에서 제안한 방법은 기존 라이브러리를 통한 검색에서의 정확도보다 13.7% 증가한 53.9%의 정확도를 보인다.