蜘蛛膜下腔 알콜 遮斷에 依한 疼痛治療

朴욱 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.3

From November, 1976 to August, 1977. We have had experience of the eight subarachnoid injections of absolute ethyl alcohol for the pain relief of nonresectable rectal and sigmoid colon cancer in four male patients. 1. The amount of the injected alcohol was between 0.3 to 0.8 ml for one a block. 2. The speed of the alcohol injection was 0.1 to 0.2 ml per minute. 3. The duration of pain relief was between 2 to 8 months after the block. 4. The complications after the block were permanent sexual impotency in Case 1 & 2, nothing in Case 3, and in Case 4 bladder retention for two weeks and sexual impotency for one week with recovery in both. There were no motor disturbances, with usual sensory function in all cases.

음식물 성상이 백서의 하악골 성장에 미치는 영향

박욱,경희문,성재현 慶北大學校 齒科大學 1991 慶北齒大論文集 Vol.8 No.2

The purpose of this study was to investigate effects of dietary consistency on mandibular growth of rats when they were fed with a soft diet and a hard diet. The experimental animals were Sprague-Dawley male rats of four weeks of age. The experimental animals were sacrificed after 2 weeks and 5 weeks. The growth changes of rat mandible was observed histologically and biometrically. The findings might be summarized as follow. 1. There was no statistically significant difference in weight change between the soft diet group and the hard diet group for the experimental period. 2. Histologically, the condylar cartilage layer of the hard diet group was greater than that of the soft diet group, and this phenomenon was pronounced in 5 week groups. 3. After 2 weeks, the length of the mandible (MF-AP, MF-PN, MF-CD, MF-PN, ME-CD, MF'-CD', IT'-CD) and the height of the mandible(CD-CD') of the hard diet group were slightly greater than those of soft diet group, but there was no statistically significant difference(P>0.05). 4. After 5 weeks, the length of the mandible(MF-AP, MF-PN, MF-CD, MF-PN, ME-CD, MF'-CD') and the height of the mandible(CD-CD') of the hard diet group were significantly greater than those of the soft diet group(P<0.05).

Heterogeneous transfection method based on encoded microparticle

박욱,권성훈,한상권,배형종 한국고분자학회 2014 한국고분자학회 학술대회 연구논문 초록집 Vol.2014 No.4

삼차 신경절 액조내 글리세롤 주입에 의한 삼차신경통 치험(12예 보고)

박욱,황경화,김용익,김일호,송후빈,김성열,Park, Wook,Hwang, Kyung-Ho,Kim, Yong-Ik,Kim, Il-Ho,Song, Hoo-Bin,Kim, Sung-Yell 대한통증학회 1988 The Korean Journal of Pain Vol.1 No.2

In 1983, Sten H$\ddot{a}$kanson first reported the clinical safety and efficacy of retrogasserian glycerol injection as a treatment of typical trigeminal neuralgia in 96 of 100 patients during a follow-up period of 1~6 years. Since September 1987, we have injected sterile pure glycerol into the trigeminal cistern using an anterior percutaneous approach via the foramen ovale (H$\ddot{a}$rtel route) for treatment of tic douloureux in 12 patients who were suffering from attacks pain of following discontinuation of carbamazepine. The results were as follows; 1) Eight patients were completely free from pain attacks with a single dose of glycerol (0.4 ml). The remaining four patients needed a second dose (0.4 ml) several days later following the single dose. The degree of patient's subjective satisfaction by those injections was very good in 11 and fair in one. 2) During the follow-up period (1~13 months), persistent sensory deficit as determined by the pin prick test, appeared to be mild in 10 and moderate in one patient. There was no sensory deficit in one patient. further attacks of pain from those injections were still noted. 3) As a transient complication, there was headache in all patient, facial hematoma in 4, nausea and vomiting in two each, and vertigo and herpes simplex in one each. In conclusion, we confirmed that the above glycerol injections into the trigeminal cistern were clinically very effective as a treatment of tic douloureux even though the follow-up period was short.

만성통의 관리

박욱 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.5

국마제신경차단은 통증의 원인규명 및 예후판정에 이용하고 각종 만성통의 효율적관리와 치료결과를 평가할 수 있는 이점이 있다. 신경파괴제에 의한 후유증과 파괴후 겪어야 할 환자의 고통을 우선 국마제신경차단으로서 간접경험토록하고 그 상태를 의사가 평가하고 치료에 이요한다. 차단의 목적은 격통억제만이 아니라 통증의 악순환을 단절시킨다. 만성통은 신경성통 근골격통 교감신경성통 내장통 그리고 대상포진후통으로 대별하고 그에 따른 통증 발생기전을 알아보았다. 각종통증의 효과적 제통법을 소개하고 의사가 지킬 차단수칙을 기술하였따.

암성통의 치료 : 역학과 약물 치료

박욱 대한통증학회 1993 The Korean Journal of Pain Vol.6 No.1

심장박동기와 마취

박욱,오흥근 한국의 현대의학사 1975 한국의 현대의학 Vol.8 No.2

추간공 외측으로 변위된 경막외 카테터로 인한 편측 경막외마취 : 증례 보고

옥시영,정민규,백영희,김상호,김순임,김선종,박욱 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

Epidural block is a well-established anesthetic method and continuous epidural catheterization is a popular and effective procedure for postoperative analgesia. However, continuous epidural catheterization has associated with complications such as venous puncture, dural puncture, subarachnoid cannulation, suboptimal catheter placement and paresthesia because the tip of the epidural catheter touches the nerves of the dura in the epidural space. We would describe that epidural catheter accidentally passed out of epidural space through an intervertebral foramen. A 82-years old woman was scheduled for radical mastectomy under epidural anesthesia. The epidural catheter was placed in standard fashion without difficulty but unilateral epidural block occured on the contralateral side of surgery. Operation was taken under general anesthesia. At the end of the operation, epidurography showed that the catheter passed out of epidural space through an intervertebral foramen and contrast media spreaded over the paravertebral space(T3-T8) with right T4 nerve root area.

경막의 Morphine, Bupivacaine 및 고장성용액 혼주시 진통지속효과에 미치는 영향

박욱 順天鄕大學 1984 순천향대학논문집 Vol.7 No.4

수술후 및 암말기 환자의 동통관리 : 주로 경막 외강에 미량의 몰핀 주입으로

황경호,김선종,김성열,전용애,김순임,박욱 순천향대학교 1981 논문집 Vol.4 No.2

Pert and his co-workers(1976) reported that opiate receptors were identified autoradiogr- aphically in the brain and the substantia gelatinosa of the posterior horn of the spinal cord. In recent stuffy of Behar (1979), small doses of morphine administered directly into the lumbar epidural space produced potent analgesia. The results of above authors prompted us to study the effect of epidurally applied sma11 doses of morphine in patient suffering from postoperative and pathologically intractable pain. In an attempt to relieve postoperative pain after lumbar epidural, caudal and brachial plexus b1ock, there were divided into two groups for study; One of these groups is control group which was injected with 2% lidocaine only and another of theme groups is morphine group which was injected with 2% lidocaine and small doses of morphine (3.5∼5.5mg). The postoperative pain relief more than 12 hours from induction in morphine group was 86.1% in lumbar epidural anesthesia and 82. 5% in caudal anesthesia. And these effective-ness was more prolonger than control groups. In the cases of pathological intractable pain relief, Case I was a patient of herpes zoster which was developed on right shoulder, upper anterior and posterior chest, and posterior auricular area with the severe pain. At 5 days after initial block, severe pain was completely subsided with 5 times of small doses of morphine injection into the epidural space. Case Ⅱ was a patient of lung cancer with severe pain and this effective pain relief was obtained for two and half days with 3 times of above same method. But after discharge from hospita1, the severe pain was developed again and above method was ineffective. Complications of this method were same with ordinarily epidural block in cases which used 2% lidocaine and slightly over came, but no loss of motor appeared in cases of morphine alone to be used. Impairment of spontaneous voiding after this method is still remained in prob1em of further study. The advantage of this method would be to provide predictab1e relief from pain without attendant lose of motor or sensory function. It is tempting to speculate that this technique may be used for postoperative pain and intractable pathological pain except cancer pain. However, further studies are needed to estab1ish the clinical applicability of epidural inject-ions of morphine, espicially with regard to the effects on longterm control of pain.