蜘蛛膜下腔 알콜 遮斷에 依한 疼痛治療

朴욱 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.3

From November, 1976 to August, 1977. We have had experience of the eight subarachnoid injections of absolute ethyl alcohol for the pain relief of nonresectable rectal and sigmoid colon cancer in four male patients. 1. The amount of the injected alcohol was between 0.3 to 0.8 ml for one a block. 2. The speed of the alcohol injection was 0.1 to 0.2 ml per minute. 3. The duration of pain relief was between 2 to 8 months after the block. 4. The complications after the block were permanent sexual impotency in Case 1 & 2, nothing in Case 3, and in Case 4 bladder retention for two weeks and sexual impotency for one week with recovery in both. There were no motor disturbances, with usual sensory function in all cases.

암성통의 치료 : 역학과 약물 치료

박욱 대한통증학회 1993 The Korean Journal of Pain Vol.6 No.1

만성통의 관리

박욱 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.5

국마제신경차단은 통증의 원인규명 및 예후판정에 이용하고 각종 만성통의 효율적관리와 치료결과를 평가할 수 있는 이점이 있다. 신경파괴제에 의한 후유증과 파괴후 겪어야 할 환자의 고통을 우선 국마제신경차단으로서 간접경험토록하고 그 상태를 의사가 평가하고 치료에 이요한다. 차단의 목적은 격통억제만이 아니라 통증의 악순환을 단절시킨다. 만성통은 신경성통 근골격통 교감신경성통 내장통 그리고 대상포진후통으로 대별하고 그에 따른 통증 발생기전을 알아보았다. 각종통증의 효과적 제통법을 소개하고 의사가 지킬 차단수칙을 기술하였따.

삼차 신경절 액조내 글리세롤 주입에 의한 삼차신경통 치험(12예 보고)

박욱,황경화,김용익,김일호,송후빈,김성열,Park, Wook,Hwang, Kyung-Ho,Kim, Yong-Ik,Kim, Il-Ho,Song, Hoo-Bin,Kim, Sung-Yell 대한통증학회 1988 The Korean Journal of Pain Vol.1 No.2

In 1983, Sten H$\ddot{a}$kanson first reported the clinical safety and efficacy of retrogasserian glycerol injection as a treatment of typical trigeminal neuralgia in 96 of 100 patients during a follow-up period of 1~6 years. Since September 1987, we have injected sterile pure glycerol into the trigeminal cistern using an anterior percutaneous approach via the foramen ovale (H$\ddot{a}$rtel route) for treatment of tic douloureux in 12 patients who were suffering from attacks pain of following discontinuation of carbamazepine. The results were as follows; 1) Eight patients were completely free from pain attacks with a single dose of glycerol (0.4 ml). The remaining four patients needed a second dose (0.4 ml) several days later following the single dose. The degree of patient's subjective satisfaction by those injections was very good in 11 and fair in one. 2) During the follow-up period (1~13 months), persistent sensory deficit as determined by the pin prick test, appeared to be mild in 10 and moderate in one patient. There was no sensory deficit in one patient. further attacks of pain from those injections were still noted. 3) As a transient complication, there was headache in all patient, facial hematoma in 4, nausea and vomiting in two each, and vertigo and herpes simplex in one each. In conclusion, we confirmed that the above glycerol injections into the trigeminal cistern were clinically very effective as a treatment of tic douloureux even though the follow-up period was short.

Heterogeneous transfection method based on encoded microparticle

박욱,권성훈,한상권,배형종 한국고분자학회 2014 한국고분자학회 학술대회 연구논문 초록집 Vol.2014 No.4

심장박동기와 마취

박욱,오흥근 한국의 현대의학사 1975 한국의 현대의학 Vol.8 No.2

음식물 성상이 백서의 하악골 성장에 미치는 영향

박욱,경희문,성재현 慶北大學校 齒科大學 1991 慶北齒大論文集 Vol.8 No.2

The purpose of this study was to investigate effects of dietary consistency on mandibular growth of rats when they were fed with a soft diet and a hard diet. The experimental animals were Sprague-Dawley male rats of four weeks of age. The experimental animals were sacrificed after 2 weeks and 5 weeks. The growth changes of rat mandible was observed histologically and biometrically. The findings might be summarized as follow. 1. There was no statistically significant difference in weight change between the soft diet group and the hard diet group for the experimental period. 2. Histologically, the condylar cartilage layer of the hard diet group was greater than that of the soft diet group, and this phenomenon was pronounced in 5 week groups. 3. After 2 weeks, the length of the mandible (MF-AP, MF-PN, MF-CD, MF-PN, ME-CD, MF'-CD', IT'-CD) and the height of the mandible(CD-CD') of the hard diet group were slightly greater than those of soft diet group, but there was no statistically significant difference(P>0.05). 4. After 5 weeks, the length of the mandible(MF-AP, MF-PN, MF-CD, MF-PN, ME-CD, MF'-CD') and the height of the mandible(CD-CD') of the hard diet group were significantly greater than those of the soft diet group(P<0.05).

경막의 Morphine, Bupivacaine 및 고장성용액 혼주시 진통지속효과에 미치는 영향

박욱 順天鄕大學 1984 순천향대학논문집 Vol.7 No.4

경막외 Morphine, Bupivacaine 및 고장성용액 혼주시 진통지속효과에 미치는 영향

박욱 순천향대학교 1984 논문집 Vol.7 No.4

Recent studies have shown that narcotic drugs produce an unusually intense, prolonged and segmental analgesic action in man when injected into the spinal subarachnoid or epidural space (Wang et al, 1979; Behar et al, 1979; Cousins et al, 1979; Magora et al, 1980; Johnston and McCaughey, 1980). Since 1960, many investigators claimed that low molecular weight (LMW) dextran increased the clinical duration of lidocaine (Loder, 1960; Loder, 1962), tetracaine (Chinn and Wirjoatmadja, 1967) and bupivacaine (Kaplan et al, 1975) in man but the mechanism of the action of dextran was unclear. But Curtiss and Scurlock (1979), and Buckley and Fink (1979) claimed that LMW dextran has no effect on the duration of action of bupivacaine in animal studies. The present study was performed to evaluate the clinical efficacy of analgesia by the thoracic epidural injection of morphine and bupivacaine mixture for the relief pain due to fractured or contused ribs, to evaluate the duration of analgesic effect by the use of the above mixture in a hypertonic solution (dextran 70 or 50% dextrose in water) and to observe the possibility of improvement in the lung function after the pain block. The complications following the pain block were also observed. The 50 single thoracic epidural injections of the mixture were divided into three groups: Group 1(n=15) served as a control group and drugs used for the relief of pain were as follows (Mean±S.D.): morphine (2.13±1.94 mg), 0.5% bupivacaine (3.10±1.04 ml) and 0.9% saline (3.64±1.11 ml). Group 2(n=16) served as an experimental group and drugs were as follows (Mean± S.D.): morphine (2.13±0.72 mg), 0.5% bupivacaine (3.06±0.77 ml) and dextran 70(3.75±1.29 ml). Group 3(n=19) served as an experimental group and drugs were as follows (Mean± S.D.): morphine (2.42±0.51 mg), 0.5% bupivaeaine (3.21±0.71 mg) and 50% dextrose in water (3.68±1.11 ml). The results are as follows: 1) The number of patients who obtained excellent and good analgesic effects following the block were greater in the experimental Group 2(94%) and Group 3(90%) than those of the control Group 1(80%). 2) The duration of pain relief which lasted more than 3 days after epidural block was longer in the experimental Group 2(81%) and Group 3(75%) than those of the control Group 1(67%). 3) The pulmonary reserve(FVC%+FEV1.0%) of 27 cases who were treated by the pain block between 1 and 31 days following the chest injury was increased to about 13% than those before the block, and that of 13 cases between 32 and 82 days following the hest injury was decreased to about 4% than those before the block. 4) Of the complications following the pain block, there were 5 cases(10%) of nausea within 2 hours following the block, 4 cases(8%) of vomiting after 2hours following the block, 10 cases(20%) of pruritus after 3~4 hours following the block, 17 cases(34%) of transient uriary retention which lasted 8 to 19 hours, 3 cases(6%) of headache within 2 hours following the block and 2 cases(4%) of dural puncture. In conclusion, it is suggested that the clinical duration of analgesic effect produced by morphine and bupivacaine mixture can be prolonged by addition of the hypertonic solution to the mixture.

추간공 외측으로 변위된 경막외 카테터로 인한 편측 경막외마취 : 증례 보고

옥시영,정민규,백영희,김상호,김순임,김선종,박욱 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

Epidural block is a well-established anesthetic method and continuous epidural catheterization is a popular and effective procedure for postoperative analgesia. However, continuous epidural catheterization has associated with complications such as venous puncture, dural puncture, subarachnoid cannulation, suboptimal catheter placement and paresthesia because the tip of the epidural catheter touches the nerves of the dura in the epidural space. We would describe that epidural catheter accidentally passed out of epidural space through an intervertebral foramen. A 82-years old woman was scheduled for radical mastectomy under epidural anesthesia. The epidural catheter was placed in standard fashion without difficulty but unilateral epidural block occured on the contralateral side of surgery. Operation was taken under general anesthesia. At the end of the operation, epidurography showed that the catheter passed out of epidural space through an intervertebral foramen and contrast media spreaded over the paravertebral space(T3-T8) with right T4 nerve root area.