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Case report of Toxocara canis migration to canine brain
류문영,이경현,정지열,배유찬,이현경,박우희,윤순식,문운경,이명헌 한국예방수의학회 2013 예방수의학회지 Vol.37 No.2
Toxocara canis is a gastrointestinal helminthe of dogs found all over the world. When dogs ingest the infectious eggs of Toxocara canis, the eggs hatch and larvae penetrate the intestinal wall carried by migration to a wide variety of tissues. Despite its zoonotic effects, there have been few reports on dogs diagnosed as canine ascaridiasis in Korea. In this report, we present a case of canine toxocariasis by histopathologic finding and PCR assay. H & E stain showed granulomatous inflammation and intralesional larva in organs and even the cortex of the cerebellum. Toxocara canis was confirmed in the PCR assay where DNA was extracted from heart, liver, and cerebellum.
류문영,정지열,이경현,허지웅,배유찬,이현경,백강현,이보람,진영화,김재명,이명헌,윤순식,Rhyoo, Moon-Young,Jung, Ji-Youl,Lee, Kyung-Hyun,Her, Ji-Woong,Bae, You-Chan,Lee, Hyun-Kyoung,Baek, Kang-Hyun,Lee, Bo-Ram,Jean, Young-Hwa,Kim, Jae-Myung 대한수의학회 2013 大韓獸醫學會誌 Vol.53 No.4
Two Korean black goat (approx. 2 and 3 years old) showing diarrhea and chronic weight loss were submitted to Animal and Plant Quarantine Agency. At necropsy, there were thickening of small intestine and enlargement of mesenteric lymph nodes. Microscopically, they had granulomatous enteritis in the small and large intestine and granulomatous lymphadenitis. By polymerase chain reaction (PCR) and acid fast stain, strong positive reaction and acid-fast rod bacteria were detected. According to the result of histopathology and PCR, we confirmed this case as Johne's disease. As far as we know, this is the first report of Johne's disease in Korean black goat.
류문영,정지열,허지웅,이명헌,구경녀,최권락,윤순식,Rhyoo, Moon-Young,Jung, Ji-Youl,Her, Ji-Woong,Lee, Myoung-Heon,Ku, Kyung-Nyer,Choi, Kwon-Rac,Yoon, Soon-Seek 대한수의학회 2014 大韓獸醫學會誌 Vol.54 No.4
In this study, we describe a case of epitheliogenesis imperfecta (EI) observed in the fetus of Korean native cattle. The fetus had multifocal areas of skin defect, especially on the distal portions of the four limbs, and the affected areas were bright-red and glistening. Histopathologically, these areas were characterized by complete absence of squamous epithelium, infiltration of inflammatory cells into the dermis, atrophy of hair follicles, sebaceous and sweat glands. To the best of our knowledge, this is the first report of epitheliogenesis imperfecta in Korean native cattle.
박우희 ( Woo Hee Park ),류문영 ( Moon Young Rhyoo ),이현경 ( Hyun Kyoung Lee ),최은진 ( Eun Jin Choi ),소병재 ( Byung Jae So ),이경현 ( Kyung Hyun Lee ) 한국동물위생학회 2015 韓國家畜衛生學會誌 Vol.38 No.4
Primary renal tumors are uncommon in dogs with prevalence rate of approximately 1%. Renal carcinoma originating from epithelium of proximal convoluted tubules are more likely to be affected to Middle-aged dogs (average age, 8y), males about twice as often as bitches. A 10-year-old, female, German Shepherd dog with history of anorexia, vomitting and hematuria was referred to the Animal Disease Diagnostic Division in Animal and Plant Quarantine Agency. The dog was necropsied and several organs were collected, fixed in 10% phosphate-buffered formalin, embedded in paraffin wax and sectioned for histopathology. Grossly, the kidneys were bilaterally enlarged (18×12×8 cm; left, 18×10×8 cm; right). The numerous cysts varying sizes from 3 to 6 cm in diameter were protruding from the surface of both kidney. A large nodule (10×6×6 cm) was discovered between cardiac and diaphragmatic lobe in the right lung. Immunohistochemical examination revealed strong positive reaction to cytokeratin and ki-67 in the nuclei of the epithelial tumor cells. But showed negative reactions to vimentin and CD10. Based on the pathological and immunohistochemical examination, we diagnosed as the bilateral renal cystadenocarcinoma in German shepherd dog.