국립공원 관리를 위한 해양생태계 장기 모니터링 프로그램의 발전 방향

이채린(Chae-Lin Lee),유재원(Jae-Won Yoo),정병관(Byungkwan Jeoung),김창수(Chang-Soo Kim),안동식(Dong-Sik Ahn),김성태(Sungtae Kim),성은주(Eun-Ju Sung),김성현(Sung-Hyun Kim),정수영(Su-Yeoung Jeong),박영석(Young-Seuk Park) 국립공원연구원 2021 국립공원연구지 Vol.12 No.2

생태계 변화의 모니터링은 효율적 생태계 관리를 위한 기초 정보 수집을 위해 중요한 과정이다. 많은 생태 현상과 그 과정은 오랜 시간에 걸쳐 진행되므로 국립공원의 지속적인 보전 및 효율적 관리를 위해 생태계 모니터링은 장기적으로 이루어질 필요가 있다. 본 연구는 국내외 장기 모니터링 프로그램 사례 분석을 통해 성공적인 장기 모니터링을 위한 방법으로써, 최적화된 모니터링 설계, 표준화된 운용방안 마련, 인적 자원 및 DATA 관리 체계 수립, 안정적인 재정 마련 및 후속지원 등을 제시하였다. 이를 바탕으로, 현재 10년 넘게 수행되고 있는 ‘HS호 유류유출 사고 해역 장기 모니터링 프로그램’의 발전 방향으로 적응형 모니터링 방식이 적용된 표준화된 프로토콜의 정립, QA/QC와 지속적인 자료 관리, 조사 항목의 연계성 강화 등의 구체적 방안을 제안한다. Monitoring ecosystem changes is an important process for collecting basic information for ecosystem management. Since many ecological phenomena and their processes take place over a long period of time, it is necessary to conduct long-term monitoring of ecosystems for the continuous conservation and efficient management of national parks. This study suggested an optimized monitoring design, standardized operation plan, human resource and data management system, stable financial preparation and follow-up support as methods for successful long-term monitoring through case analysis of domestic and foreign long-term monitoring programs. Based on this, it proposes specific measures such as establishing a standardized protocol with adaptive monitoring methods, continuous data management with QA/QC, and strengthening the linkage of investigation items in the development direction of the “HS oil spill accident long-term monitoring program” that has been conducted for more than a decade.

개에서의 膀胱結石 手術3例

김명철,장석진,이교영,김남중,변홍섭,박명호 충남대학교 수의과대학 동물의과학연구소 1995 動物醫科學硏究誌 Vol.3 No.-

Three dogs which show clinical signs of cystic calculi with anorexia, hematuria, stranguria, dribbling of urine, and pain in posterior abdomen, were referred, and diagnosed as cystic calculi by radiography and ultrasonography. Removal of urinary cystic calculi was performed by urinary cystotomy. Calculi, removed surgically, were analyzed chemically and microscolically. Calculi from three patient dogs were calcium carbonate in all. After the removal of calculi recurrence of urolith were not observed up to nowadays for about 4-10 months.

Pseudocercospora dendrobii에 의한 덴드로비움 검은잎마름병

권진혁,박창석 한국균학회 2002 韓國菌學會誌 Vol.30 No.2

2001년 경상남도 창녕군 남지읍 덴드로비움 재배포장에서 잎에 검은 잎마름 증상이 심하게 발생하였다. 병징은 아래 잎에 원형 또는 부정형의 점무늬가 생기며 표면은 옅은 갈색의 작은 함몰된 병반이 차차 증가하여 검게 변하면서 썩고 나중에 회색을 띤 검은색으로 말라죽으면서 낙엽이 된다. 조사한 포장에서 발생율은 64.8%이었다. 균사의 색깔은 짙은 올리브색이고, 분생자병은 옅은 회갈색을 띠며 5∼10개의 격벽을 가지고 분지하며 끝 부분이 가늘고 둔하다. 크기는 63∼164×3.2∼4.9㎛이었다. 분생포자는 옅은 올리브색이며 가늘고 긴 곤봉모양이며 곧거나 약간 굽으로 1∼5개 격벽을 가지며, 크기는 46∼98×3.2∼3.9㎛이었다. 균사 생육적온은 20℃이었다. 이 병원균의 병징 및 균학적 특징, 병원성을 검정한 결과, P. dendrobii에 의한 덴드로비움 검은잎마름병으로 명명하고자 제안한다. Sooty leaf blight was found on Dendrobium sp. in several farmers' fields located in Namji-eup, Changnyeong-gun, Gyeongnam province Korea in 2001. Symptoms of the disease appeared on leaves. Sooty leaf spots were started with amphigenous, subcircular to irregular spots, with light grayish brown to black color with definite margin lines on the upper surface of leaves. Infected leaves became defoliated and whole plants eventually were died. The infection rates of the disease in the surveyed area reached up to 64.8% in the early September. Conidiophores of the causal fungus were dark grayish brown in color, densely fasciculate, straight, curved to sinuous, branched, 5∼10 septate and 63∼164×3.2∼4.9 ㎛ in size. Conidia were pale to olivaceous in color, obclavatecylindric, straight to slightly curved in shape, 1∼5 septate and 46∼98×3.2∼3.9 ㎛ in size. The optimum temperature for mycelial growth of the fungus was 25℃. The fungus was identified as Pseudocercospora dendrobii on the basis of its mycological characteristics. This is the first report on sooty leaf light of Dendrobium sp. caused by Pseudocercospora dendrobii in Korea.

부산시 공장지역·주거지역 하천의 수질특성분석

문종익,임영석,박광현,김석택,성낙창,박출재 동아대학교 환경문제연구소 2000 硏究報告 Vol.23 No.1

This study is carried out to investigate the water quality changes in Busan Metropolitan streams. The results are as follows. In Busan Metropolitan streams, the loading rates of contaminants are greater in industrial waste water streams than domestic waste water streams. Some sampling points show a little high loading in autumn, but this needs more investigation to make clear the causes. The level of organic contaminants(BOD_(5) and COD_(MN)) is found to be low and does not show seasonal variation in domestic waste water streams. But, the level of organic contaminants in industrial waste water streams is relatively high and seems to be seasonally variable, which is affected by other factors. The nutrient materials, such as nitrogen(as T-N, about 20mg/L) and phosphorus(as T-P, about 2.0mg/L), are abundant than Nak Dong River and the general trends of contaminants level are similar to those of organic contaminants.

Safety Evaluation of Tobacco Substitute (Herbrette); Inhalation Toxicity, Mutagenicity and Immunotoxicity

Kyung Seuk Song,Kun Ho Park,Gi Yong Yoo,Sung-Ok Song,Hyun Woo Kim,Jun Sung Kim,Jin Hong Park,Guk Joung Eu,Jin Hua,Hyun Sun Cho,Soon Kyung Hwang,Seung Hee Chang,Arash Minai Tehrani,Kyeong Nam Yu,Chan H 한국독성학회 2004 Toxicological Research Vol.20 No.4

Inhalation toxicity, mutagenicity, and immunotoxicity tests were performed using a smoke generation system to investigate the safety of Herbrette, a tobacco substitute made with the leaves of Perilla frutescens. ICR mice were exposed to nicotine-free Herbrette smoke with concentrations of 0 (control), 4.08 ± 1.32 mg/㎥ (low dose), 7.72 ± 2.14 mg/㎥ (medium dose) and 12.83 ± 1.69 mg/㎥ (high dose) total particulate matters (TPM) for 4 weeks. When compared to the control group, the body weights, organ weights in the exposed groups did not show any significant differences. However, certain change of several serum chemical data and biochemical parameters were observed, however, the changes were within normal physiological ranges. Moreover, no changes in organ weight, and no gross/microscopic changes were observed between the exposed and control groups. Salmonella typhimurium reverse mutation, in vivo chromosomal aberration and micronucleus assays revealed that Herbrette did not induce mutagenicity. Upon evaluation of peripheral cellular immunity of mice through in vitro lymphocyte proliferation assay, no significant difference was observed in mean stimulation index between the exposed and control groups. Taken together, our results strongly suggest that Herbrette may not cause toxicity on mice under current condition.

90-Day Inhalation Toxicity of Dimethylamine in F344 Rats

Kyung Seuk Song,Kun Ho Park,Jeong Hyun Kim,Dong Un Han,Chan Hee Chae,Sung Jin Park,Hyun Woo Kim,Jun Sung Kim,Jin Hong Park,Guk Joung Eu,Jin Hua,Hyun Sun Cho,Soon Kyung Hwang,Seung Hee Chang,Kyeong Nam 한국독성학회 2005 Toxicological Research Vol.21 No.2

Dimethylamine (DMA) is a widely used commodity chemical with few toxicity data. Groups of 10 male and female F-344 rats were exposed by inhalation to 0, 5, 10, 20, 40 and 80 ppm of DMA for 6 hrs/day, 5 days/week for 90 days. The changes of body weight, organ weight, hematology, clinical chemistry, and histopathological changes were evaluated after the exposure. As the results, the body weight was significantly decreased at 80 ppm in male and female rats (p<0.05). The absolute lung weight showed no statistically significant changes in any group. In contrast, the relative lung weight significantly increased at 80 ppm in male and female rats (p<0.05). Erythrocytes, mean cell hemoglobin, leukocytes, neutrophil, and platelet numbers were significantly increased in male and female at 40 or 80 ppm of DMA (p<0.05, p<0.01). In addition, the serum values of total protein, urea nitrogen were increased in male and creatine kinase, total protein were increased in female rats at 40 or 80 ppm (p<0.05, p<0.01). Histopathological examinations of the male and female lung samples showed slight hyperplasia and congestion at 80 ppm. Taken together, our study revealed that maximum tolerated dose of DMA would be over 40 ppm

Safety Evaluation of Tobacco Substitute (Herbrette); Inhalation Toxicity, Mutagenicity and Immunotoxicity

Song, Kyung Seuk,Park, Kun Ho,Yoo, Gi Yong,Song, Sung-Ok,Kim, Hyun Woo,Kim, Jun Sung,Park, Jin Hong,Eu, Guk Joung,Hua, Jin,Cho, Hyun Sun,Hwang, Soon Kyung,Chang, Seung Hee,Tehrani, Arash Minai,Yu, Kye Korean Society of ToxicologyKorea Environmental Mu 2004 Toxicological Research Vol.19 No.3

Inhalation toxicity, mutagenicity, and immunotoxicity tests were performed using a smoke generation system to investigate the safety of Herbrette, a tobacco substitute made with the leaves of Perilla frutescens. ICR mice were exposed to nicotine-free Herbrette smoke with concentrations of 0 (control), 4.08 $\pm$ 1.32 mg/$m^3$ (low dose), 7.72 $\pm$ 2.14 mg/$m^3$ (medium dose) and 12.83 $\pm$ 1.69 mg/$m^3$ (high dose) total particulate matters (TPM) for 4 weeks. When compared to the control group, the body weights, organ weights in the exposed groups did not show any significant differences. However, certain change of several serum chemical data and biochemical parameters were observed, however, the changes were within normal physiological ranges. Moreover, no changes in organ weight, and no gross/microscopic changes were observed between the exposed and control groups. Salmonella typhimurium reverse mutation, in vivo chromosomal aberration and micronucleus assays revealed that Herbrette did not induce mutagenicity. Upon evaluation of peripheral cellular immunity of mice through in vitro lymphocyte proliferation assay, no significant difference was observed in mean stimulation index between the exposed and control groups. Taken together, our results strongly suggest that Herbrette may not cause toxicity on mice under current condition.

Aspects of Style in Reginald Pecock's English

Chang Seuk Park(朴昌錫) 啓明大學校 人文科學硏究所 1973 東西文化 Vol.6 No.-

Reginald Pecock's Purpose and Style in Writing

Park, Chang Seuk 한국영어영문학회 1973 영어 영문학 Vol.48 No.-

Melittin inhibits TGF-β-induced pro-fibrotic gene expression through the suppression of the TGFβRII-Smad, ERK1/2 and JNK-mediated signaling pathway.

Park, Su-Hyun,Cho, Hyun-Ji,Jeong, Yun-Jeong,Shin, Jae-Moon,Kang, Jeong-Han,Park, Kwan-Kyu,Choe, Jung-Yoon,Park, Yoon-Yub,Bae, Young-Seuk,Han, Sang-Mi,Moon, Sung-Kwon,Kim, Wun-Jae,Choi, Yung Hyun,Chang Institute for Advanced Research in Asian Science a 2014 The American journal of Chinese medicine Vol.42 No.5

<P>Renal fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM) proteins such as type I collagen, fibronectin, and by the increased expression of PAI-1. This study evaluated the anti-fibrotic effect of bee venom and its major compounds (melittin and apamin) on TGF-β-induced pro-fibrotic gene expression. Bee venom and melittin significantly suppressed type I collagen, fibronectin, and PAI-1 protein expression in the TGF-β-treated kidney fibroblast. However, apamin only inhibited the expression of fibronectin and type I collagen. These results indicated that the inhibitory effects of bee venom on TGF-β-induced pro-fibrotic gene expression are caused by melittin. Moreover, we attempted to elucidate mechanisms underlying the anti-fibrotic effect of melittin. Melittin dramatically inhibited the phosphorylation of TGFβRII and Smad2/3. Also, melittin inhibited the phosphorylation of ERK1/2 and JNK, but not the phosphorylation of PI3K, Akt, and p38. These results suggested that melittin inhibits TGF-β-induced pro-fibrotic genes expression through the suppression of TGFβR-Smad2/3, ERK1/2, and JNK phosphorylation, and melittin can be used as a clinical drug for the treatment of fibrosis associated with renal diseases.</P>