A Study on Nano-mechanical Properties of Adsorption Layers Derived from Lubricant Additives

Yusuke Suzuki,Ryo Tsuboi,Shinya Sasaki 대한기계학회 2013 대한기계학회 춘추학술대회 Vol.2013 No.5

Estimation of starting time for gasification process in waste degradation

( Yusuke Fujitomi ),( Osamu Hirata ),( Ayako Tachifuji ),( Shinya Suzuki ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 한국폐기물자원순환학회 심포지움 Vol.2019 No.1

With rapid urbanization and population concentration in urban area of developing countries, the amount of waste generation increased and the improper treatment or disposal of waste has continuously been caused. Under such recent situation, the semi-aerobic landfill type which is effective for early waste decomposition, the improvement of leachate quality and the reduction of methane emission has increased to be adopted in developing countries. In our study, the large-scale landfill simulation tests have been conducted in order to quantitatively evaluate these effects of semi-aerobic landfill, which consequently proposed the formula for estimating the pollution load in leachate during the liquefaction process of waste decomposition.1) In this study, as a first step in making an estimation model for the amount of methane generated during the gasification process, the validity of pH as a determinant of the starting time of gasification was evaluated by comparing the measured methane generation from lysimeter (the measured value) with the value calculated by FOD model generally used for the estimation of methane production. As a result, the measured value and the calculated value almost matched after 60 months. It indicates that the gasification process started after 60 months. From the above results, it was clarified that pH is a useful determination factor of the gasification start. In addition, it was also found that the amount of methane generation during the gasification process can be estimated by using the amount of organic carbon, which is remaining in the landfill at the start of gasification process, as the DOC value of the FOD model.

Indocyanine green fluorescence videoangiography for reliable variations of supraclavicular artery flaps

Suzuki, Yushi,Shimizu, Yusuke,Kasai, Shogo,Yamazaki, Shun,Takemaru, Masashi,Kitamura, Takuya,Kawakami, Saori,Tamura, Takeshi Korean Society of Plastic and Reconstructive Surge 2019 Archives of Plastic Surgery Vol.46 No.4

Background Pedicled flaps are useful for reconstructive surgery. Previously, we often used vascularized supraclavicular flaps, especially for head and neck reconstruction, but then shifted to using thoracic branch of the supraclavicular artery (TBSA) flaps. However, limited research exists on the anatomy of TBSA flaps and on the use of indocyanine green (ICG) fluorescence videoangiography for supraclavicular artery flaps. We utilized ICG fluorescence videoangiography to harvest reliable flaps in reconstructive operations, and describe the results herein. Methods Data were retrospectively reviewed from six patients (five men and one woman: average age, 54 years; range, 48-60 years) for whom ICG videoangiography was performed to observe the skin perfusion of a supraclavicular flap after it was raised. Areas where the flap showed good enhancement were considered to be favorable for flap survival. The observation of ICG dye indicated good skin perfusion, which is predictive of flap survival; therefore, we trimmed any areas without dye filling and used the remaining viable part of the flap. Results The flaps ranged in size from $13{\times}5.5cm$ to $17{\times}6.5cm$. One patient received a conventional supraclavicular flap, four patients received a TBSA flap, and one patient received a flap that was considered to be intermediate between a supraclavicular flap and a TBSA flap. The flaps completely survived in all cases, and no flap necrosis was observed. Conclusions The TBSA flap is very useful in reconstructive surgery, and reliable flaps could be obtained by using ICG fluorescence videoangiography intraoperatively.

Proximal ligation after the side-to-end anastomosis recovery technique for lymphaticovenous anastomosis

Suzuki, Yushi,Sakuma, Hisashi,Ihara, Jun,Shimizu, Yusuke Korean Society of Plastic and Reconstructive Surge 2019 Archives of Plastic Surgery Vol.46 No.4

Background Lymphaticovenous anastomosis is an important surgical treatment for lymphedema, with lymphaticovenous side-to-end anastomosis (LVSEA) and lymphaticovenous end-to-end anastomosis being the most frequently performed procedures. However, LVSEA can cause lymphatic flow obstruction because of regurgitation and tension in the anastomosis. In this study, we introduce a novel and simple procedure to overcome this problem. Methods Thirty-five female patients with lower extremity lymphedema who underwent lymphaticovenous anastomosis at our hospital were included in this study. Eighty-five LVSEA procedures were performed, of which 12 resulted in insufficient venous blood flow. For these 12 anastomoses, the proximal lymphatic vessel underwent clipping after the anastomotic procedure and the venous inflow was monitored. Subsequently, the proximal ligation after side-to-end anastomosis recovery (PLASTER) technique, which involves ligating the proximal side of the lymphatic vessel, was applied. A postoperative evaluation was performed using indocyanine green 6 months after surgery. Results Despite the clipping procedure, three of the 12 anastomoses still showed poor venous inflow. Therefore, it was not possible to apply the PLASTER technique in those cases. Among the nine remaining anastomoses in which the PLASTER technique was applied, three (33%) were patent. Conclusions Our findings show that achieving patent anastomosis is challenging when postoperative venous inflow is poor. We achieved good results by performing proximal ligation after LVSEA. Thus, the PLASTER technique is a particularly useful recovery technique when LVSEA does not result in good run-off.

Fabrication of 8Cr-2W ferritic steel tile for reduction in toroidal magnetic field ripple on JT-60U

yusuke Kudo,K. Masaki,M. Honda,N. Miya,R. Takahashi,S. Jitsukawa,S. Sakurai,T. Sawai,T. Sasajima,T. Hayashi,Y. Suzuki 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III

The objectives are to fabricate the ferritic steel for the reduction in the toroidal magnetic field ripple on JT-60U. The ferritic steel (8Cr-2W-0.2V) is selected by saturated magnetization and fabrication processes with more than 20 tons melting are reported. Although the magnetic properties of the plates fabricated are clarified, the little variation is observed but the saturated magnetization is lower than expected. Additional material conditions are clarified to improve the saturated magnetization without degradation of mechanical properties but it is decided not to adapt this process on grounds of cost-effectivenessP

ORiginal Article : What Is the Most Effective Drug Delivery System for Cisplatin during the Treatment of Hepatic Tumors with Single-Session Transcatheter Chemotherapy? A Pilot Study

( Yusuke Kawamura ),( Kenji Ikeda ),( Taito Fukushima ),( Yuya Seko ),( Tasuku Hara ),( Hitomi Sezaki ),( Tetsuya Hosaka ),( Norio Akuta ),( Masahiro Kobayashi ),( Satoshi Saitoh ),( Fumitaka Suzuki ) The Editorial Office of Gut and Liver 2013 Gut and Liver Vol.7 No.5

Background/Aims: The aim of this study was to determine the pharmacodynamics of cisplatin following three different treatment procedures for intrahepatic arterial infusion thera-py for hepatocellular carcinoma (HCC). Methods: We divided 13 HCC patients into the following three groups: group A, lone injection of cisplatin (n=3); group B, combined injection of cisplatin and lipiodol, with embolization using small gela-tin cubes (GCs) (n=5); and group C, injection of suspended lipiodol with cisplatin powder, with embolization using small GCs (n=5). In each group, the free cisplatin concentration in the hepatic vein was measured at 0, 5, 10, and 30 minutes. Results: The mean free cisplatin concentrations were as fol-lows. For group A, the mean was 48.58 μg/mL at 0 minute, 7.31 mL at 5 minutes, 5.70 mL at 10 minutes, and 7.15 mL at 30 minutes. For the same time points, for group B, the concentrations were 8.66, 4.23, 3.22, and 1.65 μg/mL, respectively, and for group C, the concentrations were 4.81, 2.61, 2.52, and 1.75 mL, respectively. The mean area under the curve (AUC)0-infinity for the free cisplatin concentration was 7.80 in group A, 2.48 in group B, and 2.27 in group C. The AUC0-infinity for the free cisplatin concentration gradually decreased, from group A to group C. Conclusions: These results indicate that the combination of lipiodol and small GCs may be useful for delaying cisplatin drainage from the liver. (Gut Liver 2013;7:576-584)

Preoperative serum microRNAs as potential prognostic biomarkers in ovarian clear cell carcinoma

Kazuhiro Suzuki,Akira Yokoi,Kosuke Yoshida,Tomoyasu Kato,Takahiro Ochiya,Yusuke Yamamoto,Hiroaki Kajiyama 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.3

Objective: Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian carcinoma with poor prognosis. However, no effective biomarkers have been established for predicting unfavorable events, including recurrence and poor prognoses. Serum microRNAs (miRNAs) have been increasingly reported to be useful in predicting a patient’s condition and have been recognized as a potentially less-invasive source for liquid biopsy in cancer. Therefore, this study aimed to evaluate serum miRNA profiles from patients with OCCC and to establish biomarker for predicting the prognoses. Methods: The GSE106817, which included preoperative serum miRNA profiles of patients with ovarian tumors, was used, and clinical information was investigated. In all, 66 patients with OCCC were included, excluding those with other histological subtypes or insufficient prognostic information. Moreover, miRNA profiles of OCCC tissues were also examined. Results: The median follow-up period was 64.3 (8.0–153.3) months. Based on multivariable Cox regression analyses and the expression of miRNAs in OCCC tissues, miR-150-3p, miR-3195, and miR-7704 were selected as miRNA candidates associated with both progression-free survival (PFS) and overall survival (OS). Then, the prognostic index was calculated based on expression values of 3 serum miRNAs. Kaplan-Meier survival analysis indicated that the prognostic index was significantly predictive of PFS and OS (p=0.004 and p=0.012, respectively). Conclusion: Preoperative serum miRNA profiles of miR-150-3p, miR-3195, and miR-7704 can be used to potentially predict the prognosis of patients with OCCC.

Proximal ligation after the side-to-end anastomosis recovery technique for lymphaticovenous anastomosis

Yushi Suzuki,Hisashi Sakuma,Jun Ihara,Yusuke Shimizu 대한성형외과학회 2019 Archives of Plastic Surgery Vol.46 No.4

Background Lymphaticovenous anastomosis is an important surgical treatment for lymphedema, with lymphaticovenous side-to-end anastomosis (LVSEA) and lymphaticovenous endto- end anastomosis being the most frequently performed procedures. However, LVSEA can cause lymphatic flow obstruction because of regurgitation and tension in the anastomosis. In this study, we introduce a novel and simple procedure to overcome this problem. Methods Thirty-five female patients with lower extremity lymphedema who underwent lymphaticovenous anastomosis at our hospital were included in this study. Eighty-five LVSEA procedures were performed, of which 12 resulted in insufficient venous blood flow. For these 12 anastomoses, the proximal lymphatic vessel underwent clipping after the anastomotic procedure and the venous inflow was monitored. Subsequently, the proximal ligation after side-to-end anastomosis recovery (PLASTER) technique, which involves ligating the proximal side of the lymphatic vessel, was applied. A postoperative evaluation was performed using indocyanine green 6 months after surgery. Results Despite the clipping procedure, three of the 12 anastomoses still showed poor venous inflow. Therefore, it was not possible to apply the PLASTER technique in those cases. Among the nine remaining anastomoses in which the PLASTER technique was applied, three (33%) were patent. Conclusions Our findings show that achieving patent anastomosis is challenging when postoperative venous inflow is poor. We achieved good results by performing proximal ligation after LVSEA. Thus, the PLASTER technique is a particularly useful recovery technique when LVSEA does not result in good run-off.

Indocyanine green fluorescence videoangiography for reliable variations of supraclavicular artery flaps

Yushi Suzuki,Yusuke Shimizu,Shogo Kasai,Shun Yamazaki,Masashi Takemaru,Takuya Kitamura,Saori Kawakami,Takeshi Tamura 대한성형외과학회 2019 Archives of Plastic Surgery Vol.46 No.4

Background Pedicled flaps are useful for reconstructive surgery. Previously, we often used vascularized supraclavicular flaps, especially for head and neck reconstruction, but then shifted to using thoracic branch of the supraclavicular artery (TBSA) flaps. However, limited research exists on the anatomy of TBSA flaps and on the use of indocyanine green (ICG) fluorescence videoangiography for supraclavicular artery flaps. We utilized ICG fluorescence videoangiography to harvest reliable flaps in reconstructive operations, and describe the results herein. Methods Data were retrospectively reviewed from six patients (five men and one woman: average age, 54 years; range, 48–60 years) for whom ICG videoangiography was performed to observe the skin perfusion of a supraclavicular flap after it was raised. Areas where the flap showed good enhancement were considered to be favorable for flap survival. The observation of ICG dye indicated good skin perfusion, which is predictive of flap survival; therefore, we trimmed any areas without dye filling and used the remaining viable part of the flap. Results The flaps ranged in size from 13×5.5 cm to 17×6.5 cm. One patient received a conventional supraclavicular flap, four patients received a TBSA flap, and one patient received a flap that was considered to be intermediate between a supraclavicular flap and a TBSA flap. The flaps completely survived in all cases, and no flap necrosis was observed. Conclusions The TBSA flap is very useful in reconstructive surgery, and reliable flaps could be obtained by using ICG fluorescence videoangiography intraoperatively.

Electrochemical Behavior of Co-Cr alloy in Neutral Solution

Ryouji Suzuki,Kazuhiko Noda,Yusuke Tsutsumi,Takao Hanawa 한국표면공학회 2010 한국표면공학회 학술발표회 초록집 Vol.2010 No.11

The Co-Cr alloys which have an excellent mechanical property and corrosion resistance are known as one of the most important metallic biomaterials. In this study, the electrochemical behavior of Co-Cr alloy in deaerated different electrolytes was investigated by using polarization curve measurements. Ti and stainless steels (Type 316) were used as a comparing material. The Co-Cr alloy has high corrosion resistance compared with the stainless steel in NaCl solution. The current increasing with the pitting corrosion was appeared in polarization curves of stainless steels. But it was disappeared in polarization curves of Co-Cr alloy. The passive state of the Co-Cr alloys was kept even in the pitting region of the case of stainless steels. The passive film on the Co-Cr alloy is stable as same as the film on Ti. According to the polarization behavior, the Co-Cr alloys are expected to use as the biomaterials.