급성 골수성 백혈병 환자에서 발생한 침습성 아스페르길루스중에 대한 수술적치료 1 예

배영환;어원식;어상민;김승만 김태영;박수영;서영경;정은주;안효정 인제대학교 2011 仁濟醫學 Vol.32 No.-

Invasive pulmonary aspergillosis is known to have a poor prognosis and major cause of morbidity and motality in patients with hematologic disease. Without adequate therapy, invasive pulmonary aspergillosis will almost always progress to fatal pneumonia. Early administration of antifungal agents in patient with invasive pulmonary aspergillosis is most important. And surgical resection of aspergillous-infected tissue may be useful in patients with lesions that are contiguous with great vessel and lesions causing hemoptysis. We reported a rare case of surgical resection as curative treatment for invasive pulmonary aspergillosis patient in 58-year-old man who had the history of acute myeloid leukemia.

장기간 항갑상선제 투여 후 임의 중단 뒤 재복용시 발생한 무과립구증 1 예

김승만;김태영;박수영;배영환;서영경 정은주;김태균;권민정;박정현;이순희 인제대학교 2011 仁濟醫學 Vol.32 No.-

Agranulocytosis, one of the major side effects of antithyroid a gents, probably occurs in less than 0.25% of cases treated with antithyroid agents. It usually occurs within the first several weeks or months after the initiation of therapy, when drug dosage is higher. Most reported cases of agranulocytosis have occurred during the first 3 months of therapy. We describe here a rare case that did not experience the side effect for 6 years of antithyroid agent treatment but presented with agranulocytosis in one month after re-exposure. It suggests that the major side effect such as agranulocytosis can occur in patients who had undergone prior uneventful antithyroid drug therapy.

남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

시판중인 보이차 추출물의 생리활성

고수지,서희,박영현 순천향대학교 기초과학연구소 2011 순천향자연과학연구 논문집 Vol.17 No.2

This study was performed to assess the antioxiant of puer tea ethanol extract by measuring total polyphenol and flavonoid contents, DPPH radical capacity, ABTS radical capacity. Total polyphenol and flavonoid contents of puer tea Metyl alcohol extraction were and mg/g. The ABTS radical scavending acticity of puer tea Metyl alcohol extraction were 76.8% at 100㎍/ml.

광주지역 소아에서 유행한 호흡기바이러스 유행양상 분석

서진종,김민지,김선희,기혜영,정재근,김은선,박종태,김경심,이수야,김명권,정윤석 대한감염학회 2008 감염과 화학요법 Vol.40 No.4

Background : This investigation was to perform the epidemiological surveillance and genetic analysis on respiratory viral agents from children with acute respiratory infections in Gwangju. Materials and Methods : For this study, 3,695 specimens obtained from patients with acute respiratory infections were collected by collaboration with pediatric hospitals in Gwangju between 2005 and 2007. Specimens were screened for 8 respiratory viruses including influenza viruses (IFV), human rhinoviruses (HRV), human coronaviruses (HCoV), adenoviruses (ADV), parainfluenza viruses (PIV), human enteroviruses (HEV), respiratory synthitial viruses (RSV) and human bocaviruses (HBoV). Respiratory viruses were detected using multiplex (RT) PCR with viral specific primers. Results : Out of 3,695 specimens, the ratio of virus detection was 24.9% (919). Overall, HRV (35.5%) and IFV (34.9%) were the most common viruses found, followed by HBoV (14.8%), HCoV (10.6%), RSV (3.7%), ADV (3.4%), PIV (3.2%) and HEV (3.0%). In addition, multiple infections were detected in 80 patients (8.7%). When the prevalence was analyzed according to season, HBoV, IFV and HCoV showed two epidemic points in late spring and early winter. ADV, HRV, RSV PIV and HEV, however, were all found to have only one epidemic point, with RSV being most common during winter and the others being most prominent during spring. Conclusions : Through this epidemiological surveillance, the respiratory viruses prevalent in children in Gwanaju area were investigated. We strongly recommend the development of nationwide policy for the management of prevalent respiratory virus that includes long term collection of data and samples, vaccine development and prevention education of the misuse of antibiotics.

국제물류 환경변화에 따른 경제자유구역 물류거점기능 강화방안

서수완,박영태 한국물류학회 2005 물류학회지 Vol.15 No.1

본 연구는 중국 물류시장의 급속한 성장에 대응하고 한국내 글로벌 물류기업 유치 및 물류산업 육성을 위한 대안의 일환으로 경제자유구역의 물류거점기능 강화방안을 분석하였다. 본 연구에서 검토한 바에 따르면 경제자유구역의 성공가능성은 투자대상국의 발전가능성과 시장규모, 배후연계수송능력, 물류비수준과 물류기반시설 및 화물처리시설 확보수준 및 국가지원 등의 변수에 의해 결정될 수 있으며, 아울러 한국 물류기업의 경쟁성 향상 또한 매우 중요한 변수로 간주되고 있다. 이러한 사실로부터 경제자유구역에 대한 외국기업을 비롯한 관련 물류기업의 투자를 이끌어내기 위해서는 비용요인 보다는 시장요인 개선전략을 통해 경제자유구역의 물류거점기능 강화전략이 추진되어야 한다는 결론을 도출할 수 있었다. 이는 한국 자체시장 규모를 확대시킬 수 있는 전략의 추진이 선행되어야 함을 의미하는 것이며, 이를 위해서는 국내 물류기업의 경제자유구역 참여를 확보할 수 있는 정책적 보완이 요구된다. 아울러 한국의 주요 거점지역과 외국 주요 거점간에 보다 많은 물류네트워크 관계를 형성할 수 있는 방안을 모색하는 것이 순차적인 전략이라고 판단할 수 있다. This paper investigated strengthening the function of logistics hub in free economic zone(FTZ) in order to attract investments from global logistics companies and to raise logistics industry. The successfully probability of FTZ will be decide by potential growth of host country and market size, transportability connected with hinterland, logistics cost level, logistics infrastructure, level of cargo handling facility, government support, competitiveness of Korean logistics companies, etc. Therefore, to attract investment from the foreign companies and related logistics companies, the strategy to strengthen the function of logistics hub in FTZ have to performed through improvement of market factors rather than cost factors was deduced. It is mean that the procurement strategy to expand market size in Korea is pre-performed, and political supplementation, the investment on FTZ is guaranteed by domestic logistics companies, should be needed. Also, it is that the more and more logistics network inter major logistics hub in domestic and foreign is build will be successively strategy.

뇌성마비 환아의 발달 평가와 유발 전위, 뇌파,뇌 자기 공명 영상의 비교연구

서정수,김태민,채진목,김영경,김봉옥 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.4

수종의 레진 모노머가 우식 유발성 세균의 활성에 미치는 영향

서영주,국중기,윤정훈,김수관,이난영,이상호 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

이전의 연구에서 레진 재료를 포함한 여러 수복재료에서의 유출물이 우식 유발 세균의 성장에 영향을 줄 수 있다는 보고가 있었다. 이번 연구의 목적은 대표적인 우식 유발 세균인 Streptococcus mutans와 Streptococcus sobrinus의 성장에 대하여 레진을 구성하는 모노머들(Bis-GMA, TEGDMA, EGDMA, UDMA, HEMA, Camphoroquinone)이 어떠한 영향을 줄 수 있는지에 대하여 알아보고자 하는 것이다. 결과는 다음과 같다. 1. S. mutans와 S. sorbinus의 성장률은 6가지 레진 모노미 모두에서 0.03 m㏖/L의 농도에 서 유의할 만하게 감소되었다. 2. S. mutans의 성장률은 0.01 m㏖/L 농도의 UDMA의 0.005 m㏖/L, 0.01 m㏖/L 농도의 Camphoroquinone에서 대조군에 비하여 유의할만하게 감소되었다. 3. S. sorbinus의 성장률은 0.01 m㏖/L 농도의 HEMA. UDMA와 0.005 m㏖/L, 0,01 m㏖/L 농도의 Camphoroquinone에서 대조군에 비하여 유의할만하게 감소되었다. 4. S. sorbinus의 성장률은 0.001, 0.01, 0.03 m㏖/L 농도에서 대조군에 비하여 유의할만한 감소를 보였으며 각 실험군들 간에도 통계학적으로 유의할만한 차이를 보였다. 이상의 결과를 종합하면 레진 모노머를 적용한 모든 군에서 적용하지 않은 양성 대조군에 비해 두 세균의 증식률이 감소되었으며, 세균의 성장을 촉진하지 않은 것으로 사료된다. The purpose of this study was to examine the effects of resin composite monomers (Bis-GMA, TEGDMA, EGDMA. UDMA. HEMA, Camphorquinone) on the growth of the two cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus. We obtained the following results : 1. The growth rate of S. mutans and S. sobrinus was decreased significantly in the group of all composite resin monomer at a concentration of 0.03mmoI/L(P〈0.01). 2. The growth rate of S. mutans in the group of UDMA at a concentration of 0.01 mmol/L and the group of CQ at a concentration of 0.005 mmol/L, 0.01 mmol/L 1%-as decreased significantly compared to the control group(P〈0.01). 3. The growth rate of S. sobrinus in the group of HEMA. UDMA at a concentration of 0.01 mmol/L and the group of CQ at a concentration of 0.005mmol/L. 0.0lmmol/L was decreased significantly compared to the control group(P〈0.01). 4. The growth rate of S. sobrinus in the group of EGDMA at a concentration of 0.001, 0.01. 0.03mmol/L was decreased significantly compared t o the control group (P〈0.01) and were showed to be statistically significant difference between experimental groups(P(0.01).

충남 일부지역 초등학생의 인두에 분포하는 세균 실태조사

하서영,박수진,이보미,박솔기,박창은 남서울대학교 2012 남서울대학교 논문집 Vol.18 No.2

The distributed species and the kinds of variable microorganism in Pharynx were monitored to the elementary school child. Our purpose was to investigate the distribution of bacteria in Pharynx of child except for adults. Analysis performed the collected sample from 15 students in Chungnam area for 2 days from July 30 to July 31 in 2012. The isolated bacteria were identified by Gram stain and biochemical test using VITEKⅡsystems. The experiment on microorganism concentration of contact parts carried out and the average of total microorganism was measured. The elementary child's Pharynx were isolated and identified. The isolation rates were major distributied to Gram positive cocci, another Gram negative bacilli and Gram positive bacilli. respectively. The frequently isolated bacteria were G. adiacens. The Granulicatella adiacens is one of the fastidious Gram positive cocci previously described as nutritionally variant streptococci due to their requirement of L-cysteine, pyridoxal, or thiol compounds for growth. These bacteria have been identified as significant causative agents of endocarditis, opthalmic infections, and meningitis. Further systematic studies are necessary with an emphasis on species identification. Key Words : Microorganism, Elementary child, Pharynx and Larynx

조선대학병원에서 경험한 삼일열 말라리아의 임상적 고찰

서영선,김양수,김태균,박유환,홍순표,정춘해 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

In the five years since 1993 Malaria has made a ceaseless attack on the native Koreans as an indigenously formed disease in addition to the imported one. This study was aimed at clinical symptoms and signs of Malaria which had occurred indigenously in Cheon-Nam. 18 cases were reviewed retrospectively in this study which was composed of 17 men and 1 woman. They were admitted to Chosun Hospital because of the indigenous Malaria in 1998. Fever and chill , the most frequent symptoms in early stages made a 100% occurrence followed by general myalgia(89%) and headache(83%). Physical examination of those admitted showed the splenomegaly most frequently in 61% of the patients. It took four to ten days to visit the hospital since the symptoms first occurred in the patients. Gametocytes among the Malarial life cycle were observed most commonly (91.3%) in the occurrence of the disease and the prestages of the life cycle as well. The hematologic abnormalities observed was Anemia(89%), Thrombocytopenia(61%), and Neutropenia(50%) in the order named. On the third hospital day since giving the standard Malarial drugs parasitemia decreased remarkably (1540/㎕ : Mean parasitic concentration) and 28th day of treatment no parasitemia were found. In conclusion the patients suffering from malaria in Cheon-Nam had been in an armistice area and the symptoms were so relatively mild that the responses to treatment were good and relapses occurred. But, it requires further epidemiologic survey and more concern about the indigenous Malaria.