모과내 기능성 유용성분 용매추출공정의 최적화

전주영 ( Ju Yeong Jeon ),조인희 ( In Hee Jo ),경현규 ( Hyun Kyu Kyung ),김현아 ( Hyun A Kim ),이창민 ( Chang Min Lee ),최용희 ( Yong Hee Choi ) 한국산업식품공학회 2010 산업 식품공학 Vol.14 No.2

본 연구에서는 모과내의 여러 가지 기능성 유용성분을 효과적으로 추출하기 위해서, 모과나무의 익은 열매로 만든 약재인 모과를 사용 하였다. 모과의 기능성 유용성분용매 추출 공정의 최적 조건을 확립하고자 하였다. 모과를 에탄올에 추출하여 반응표면 분석법으로 모니터링하여 최적 용매 조건을 설정하였다. 중심합성계획법에 따라 시료에 대한 용매비(X1)와 추출온도(X2), 추출시간(X3)을 요인변수로 하고 추출수율(Y1), 총페놀 함량(Y2), 전자공여능(Y3), 갈색도(Y4), 환원당(Y5)을 종속변수로 하여 시행하였다. 실험 결과 추출수율은 추출 온도와 추출 시간에 유의하게 영향을 받음을 알 수 있었다. 안장점에서 추출조건은 시료에 대한 용매비는 26.38mL/g, 추출온도는 72.82oC, 추출시간은 74.86 min에서 최대값을 나타내었다. 총페놀 함량은 용매비와 시간에 영향을 거의 받지 않았고 추출시간에는 영향을 받았으며, 최대값은 20.70mg/mL 로 나타났다. 이때의 추출조건은 시료에 대한 용매비는 22.61mL/g, 추출온도는 84.49oC, 추출시간은 77.25 min으로 나타났다. 전자공여능은 추출온도에 따라 유의하게 영향을 받은 것으로 나타났다. 안장점에서의 추출조건인 시료에 대한 용매비 10.65mL/g, 추출온도 67.78oC, 추출시간 96.75 min에서 추출수율은 94.12%로 예측되었다. 갈색도에 대한 추출조건은 시료에 대한 용매비 23.77mL/g, 추출온도 87.27oC, 추출시간 96.68 min 일 때 안장점이 나타났다. 환원당은 시료에 대한 용매비 26.83mL/g, 추출온도 82.167oC, 추출시간 81.94 min에서 10.55mg/mL로 최대값을 나타내었고 추출시간에 영향을 받았다. In this study, various active functional components in Chinese Quince were extracted by solvent extraction method. A central composit design for optimization was applied to investigate the effects of independent variables such as solvent to sample ratio (X1), extraction temperature (X2), and extraction time (X3) on the soluble solid contents (Y1), total phenols (Y2), electron donating ability (Y3), browning color (Y4) and reducing sugar contents (Y5). It was found that extraction temperature and extraction time were the main effective factors in this extraction process. The maximum soluble solid contents of 35.77% was obtained at 26.38mL/g (X1), 72.82oC (X2) and 74.86 min (X3) in saddle point. Total phenols were rarely affected by solvent ratio and extraction time, but it was affected by extraction temperature. The maximum total phenols of 20.70% was obtained at 22.61mL/g (X1), 84.49oC (X2), 77.25 min (X3) in saddle point. The electron donating ability was affected by extraction time. The maximum electron donating ability of 94.12% was obtained at 10.65mL/g (X1), 67.78oC (X2), 96.75 min (X3) in saddle point. The maximum browning color of 0.32% was obtained at 23.77mL/g (X1), 87.27oC (X2), 96.68 min (X3) in saddle point. The maximum value of reducing sugar content of 10.55% was obtained at 26.83mL/g (X1), 82.167oC (X2), 81.94 min (X3). Reducing sugar content was affected by extraction time.

대장내시경검사의 전처치로서 항콜린제 사용에 관한 연구 : 전향적, 이중맹검법으로

박경남,한동수,이민호,최호순,박준용,손주현,이오영,함준수,전용철,송승찬,기춘석,윤병철,이종희 대한소화기내시경학회 1997 Clinical Endoscopy Vol.17 No.3

Background: Use of antispasmodic medication prior to colonoscopy is controversial but someone believes antispasmodic may improve visualization of colonic mucosa and ease colonoscope insertion. So, we designed a study to assess the effect of premedication with the antispasmodic, hyoscine-N-butyl bromide(Buscopan') on the performance of colonoscopy. Methods: This study was prospective, double blinded, randomized, controlled study, One hundred three consecutive patients were randomized to receive intravenous buscopan lml(n=52) or placebo(n=51) combined with our standard initial medication(me- peridine 50 mg and midazolam 2 mg). Insertion of colonoscopy was timed, and 100 mm visual analogue scales (VAS) were used for asscssing difficulty of procedure, colonic motility, frequency of positional change, frequency of external compression, difficulty of assistance and degree of discomfort experienced by the patients. Results: There were no significant differences of intubation time between buscopan group(mean time, 7.23 min., range 2~15) and placebo group(7.07 min., range 3-25), (p=0.83) and withdrawal time between buscopan group (6.46 min., range 2-22) and placebo group(6.76 min., range 2 25), (p=0.69). Also, there was no significant differences in intubation time between males and females(buscopan; males 7.00 min., females 7.60 min., p=0.34, placebo; males 7.0~5 min., females 7.08 min., p 0.44). The VAS scores checked by endoscopist(p=0.29), assistant(p=0.32) and patient (p=0.15) were not significantly different in both groups. There were no significant differences in intubation time, VAS scores nf endoscopist, assistant, and patients. Conclusion: Premedication with intravenous bu.opan has no advantage on colonoscopy procedure. Use of antispasmodic medication prior to colonoscopy was not considered as recommendable agent.

Casein micelle 의 조성에 관한 연구 : I. Micelle 크기 별에 따른 각 casein 의 구성비율 I. The relative amounts of individual caseins in the different casein micelles

김영교,신동철,전우민 한국낙농학회 1984 韓國酪農學會誌 Vol.6 No.1

本 實驗은 casein miceile의 크기에 따른 각종 casein의 構成成分을 究明하고자 超遠心分離機를 利用하여 casein micelle을 크기 別로 分類하고 DEAE-cellulose column chromatography를 이용하여 각 casein의 構成比率을 조사하였다. 그 結果를 要約하면 다음과 같다. 1. 脫脂乳를 100,000×g에서 각각 30分, 60分, 90分동안, 200,000×g에서 60分동안 遠心分離하였을 때 沈澱되는 casein micelle 量은 45.00%, 61.43%, 80.00% 및 95.00%였으며 沈澱되지 않는 serum casein量은 55.00%, 38.57%, 20.00% 및 5.00%였다. 2. 脫脂乳를 100,000×g에서 時間 差에 따라서 遠心分離하였을 때 각각 沈澱되는 casein micelle量은 10分間에는 全 casein量의 23.13%, 11∼30分間에는 30.26%, 31∼60分間에는 28.11%였으며, 60分問의 遠心分離에 의해서 沈澱되지 않는 serum casein은 17.79%였다. 3. 時問 差로 遠心分離하여 얻어진 casein micelle중 각 casein의 構成比率을 測定한 結果, α_s-casein, β-casein, κ-casein 및 γ-casein의 상대적인 量은 100,000×g, 10分의 pellet에서 각각 54%, 29%, 11% 및 6%였고, 100,000×g, 11∼30分의 pellet에서는 각각 54%, 28%, 13% 및 5%였고, 100,000×g, 31∼60分의 pellet에서는 각각 51%, 28%, 16% 및 5%로 나타났으며, serum casein은 44%, 29%, 19% 및 8%로 각각 나타났다. This experiment was carried out to study on the protein composition of casein micelles. Three micellar casein pellets and a serum casein were isolated at diferent time of ultracen trifugation. And the composition of individual caseins for the fractions was determined by DEAE-cellulose column chromatography. The results are summarized as follows: 1. When skimmilk was centrifuged for 30 min, 60 min and 90 min at 100,000g and for 60 min at 200,000g, the values for the sedimented casein micelles were 45.00%, 61.43%, 80.00% and 95.00% respectively and that of serum casein was 55.00%, 38.57%, 20.00% and 5.00% respectively. 2. When skimmilk was centrifuged for different time at 100,000g, the values for the sedimented casein micelles were 23.18% for 10 min.(pellet 1), 30.26% from 11 to 30 min.(pellet 2), 28.11% from 31 to 60 min.(pellet 3) and that of serum casein which was not sedimented at 60 min was 17.79% of the total casin. 3. The relative amounts of α_s-, β-, k- and γ-caseins in casein micelles obtained after different time of centrifugation were 54%, 29%, 11% and 8% in pellet 1, 54%, 28%, 13% and 5% in pellet 2, 51%, 28%, 16% and 5% in pellet 3,44%, 29%, 19% and 8% in serum casein respectively.

Variation of Harbor Oscillations in Yeongil Bay

Min­Su Jeon,Joong­Woo Lee,Jae­Hyun Jeong,Sang­Yong Yang,Young­Hwan Jeong 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.1 No.-

  Today, harbor oscillation problems are the most significant factor to consider when designing harbors serving very large ships. In coastal harbors, large vessels moored in the elastic hawsers are often displaced due to the resonance between long period waves and mooring systems. As a result, cargo handling may be interrupted and the hawsers may be broken, especially when the amplification becomes extreme. The most significant harbor confronted with harbor oscillation problem in Korea is Pohang New port. Many cases of problems are being reported by the pilot association and the local office of MOMAF (Ministry of Maritime Affairs and Fisheries). However, it is difficult to prevent the arrival of long waves causing oscillation within this harbor. Moreover, the Korean government has already started a new port plan at the mouth of Yeongil Bay without addressing the problems that have occurred in Pohang New port. This study deals with the variation of harbor oscillation due to the construction of a 4.1 km breakwater at the bay mouth including the arrangement of the new berths. Numerical methods used are in fairly standard form from the extended mile slope equation. The obtained numerical results were compared with field measurement from the previous and this will bring a certain level of discussion and consideration of variation to the future port development.

알루미늄 PEO 코팅의 결정상에 미치는 공정 조건에 대한 연구 I. Unipolar 펄스와 코팅시간

김배연,함재호,이득용,김용남,전민석,김기윤,최지원,김성엽,김광엽,Kim, Bae-Yeon,Ham, Jae-Ho,Lee, Deuk Yong,Kim, Yong-Nam,Jeon, Min-Seok,Kim, Kiyoon,Choi, Ji-Won,Kim, Sung Youp,Kim, Kwang Youp 한국결정성장학회 2014 韓國結晶成長學會誌 Vol.24 No.2

전해질로 $Na_2SiO_3$을 사용하여 A1050 알루미늄 판재를 pulse 폭 $ 2000{\mu}sec$, impulse 420 V, 400 ${\mu}$sec의 unipolar pulse로 플라즈마 전해 산화 코팅(plasma electrolytic oxidation coating)을 하여 산화 피막을 2, 5, 15, 30분에 따라 형성시킨 다음 산화피막을 분석하였다. 표면에 형성된 산화물의 결정상은 ${\alpha}-alumina$와 ${\gamma}-Alumina$로서 시간에 따른 변화는 없었다. 반응 초반에는 ${\gamma}-Alumina$가 많이 생성되었지만 시간이 갈수록 ${\gamma}-Alumina$의 양에는 변화 없이 ${\alpha}-alumina$가 많이 생겨남을 알 수 있었다. 이런 결과는 micro plasma에 의해서 ${\gamma}-Alumina$가 우선 생성되고, 이후 계속되는 micro plasma의 열에 의해서 ${\alpha}-alumina$로의 전이가 일어나기 때문으로 판단된다. Crystallographic phases of Plasma electrolytic oxidized Al alloy, A1050, were investigated. The electrolyte of PEO was $Na_2Si_2O_3$ and KOH. Unipolar pulse, $ 2000{\mu}sec$ with $400{\mu}sec+420V$ impulse, were applied for 2 min, 5 min, 15 min, and 30 min. ${\gamma}-Alumina$, as well as ${\alpha}-alumina$, was main crystal phase. ${\gamma}-Alumina$ was appeared in the beginning, then the amount of ${\alpha}-alumina$ was increased with time, but the amount of ${\gamma}-Alumina$ remained constant without any increasing. So, it is concluded that plasma gas produce ${\gamma}-Alumina$ at the first, and then ${\gamma}-Alumina$ transform ${\alpha}-alumina$ finally. During the transformation, high temperature of micro plasma gives transformation energy.

엔트로피 개념을 이용한 하천 종단고도 결정

전민우,이대규,조용수 충북대학교 건설기술연구소 2003 建設技術論文集 Vol.22 No.1

This study determines the stream mean slope, stream slope and stream longitudinal elevation based on the concept of entropy. Maximising the entropy will make the probability distribution of longitudinal profile as uniform as possible while satisfying the constraints. Using this relationship the stream longitudinal elevation formula was derived. The parameters of applied streams were determined by geomorphological factors of Dalchon stream basin obtained from Chung Cheong Buk-Do local stream consolidation scheme drawing. The derived formula of the stream longitudinal elevation was programmed using Fortran by the method of least error sum of squares between the observed streams were determined by minimizing the error sum of squares between the observed stream longitudinal profile and the simulated stream longitudinal profile. Besides, the comparative investigation was performed between the observed mean stream slope and the simulated mean stream slope obtained from the derived equation based on the obtained parameters.

고온 초전도체 Y₁Ba₂Cu₃O_7-δ(CdO)_x의 핵사중극 상호작용 연구

전인,김복수,노태호,김영훈,서용문,송승기,박영민 명지대학교 자연과학연구소 2000 자연과학논문집 Vol.19 No.-

CdO가 첨가된 고온 초전도체 Y1Ba2CU3O7-δ(CdO)x(x=0.00,0.09,0.22,0.34,0.42,0.49)를 고상 반응법으로 제작하여 상온에서 Cu 핵사중극 공명 실험을 하였다. 구리-산소 평면에 있는 63Cu(2)의 핵사중극 공명 진동수는 31.13∼31.39 MHz이고, 65Cu(2)의 공명 진동수는 28.82∼29.06 MHz이었다. 이러한 공명 진동수는 χ가 증가할수록 높은 진동수 방향으로 이동하였다. 63Cu(2)과 65Cu(2)의 NQR 공명 진동수의 비는 모든 시료가 1.08로 63Cu과 65Cu의 핵 사중극 모멘트의 비와 같았다. 구리-산소 사슬에 있는 63Cu(1)의 공명 진동수는 22.15~22.36 MHz에서 관측되었는데, χ에 따른 공명 진동수의 이동 경향은 63Cu(2)과 65Cu(2)의 경우와 비슷하였다. 선폭은 63Cu(2)과 65Cu(2)그리고 63Cu(1)의 경우 모두 약 200∼300 kHz고, 전반적으로 χ가 증가할 수록 감소하였다. 스핀-에코 방법으로 구한 스핀-스핀 이완 시간 T2는 χ가 증가함에 따라 약간씩 증가하였다. We have studied Cu-NQR in CdO-mixed high-Tc superconductor Y1Ba2Cu3O7-δ(CdO)x(x=0.00, 0.09, 0.22, 0.34, 0.42, 0.49) at room temperature prepared by solid state reaction method. In the Cu-O plane, 63Cu(2)-NQR frequencies were measured to be in the range of 31.13-31.39 MHz and those of 65Cu(2) were in the range of 28.82-29.06 MHz. The position of spectrum-peaks shifted to the higher frequency with increasing χ. The ratio of 63Cu(2) and 65Cu(2)-NQR frequencies have the value of 1.08 which is equal to the ratio of 63Cu(2) and 65Cu(2) nuclear quadrupole moment for all samples. The resonance frequencies of 63Cu(1) in the Cu-O chain have been observed in the range of 22.15-22.36 MHz and the tendency of resonance frequency behaviour with χ were nearly the same for both 63Cu(2) and 65Cu(2). The line-widths of 63Cu(2), 65Cu(2) and 63Cu(1) were observed to the value of 200∼300 kHz and they decreased with increasing χ. The spin-spin relaxation time T2 obtained by spin-echo method increased slightly with increasing χ.

COBOL 레거시 시스템의 재사용을 위한 효율적인 트리 개발

전하용,최원호,정민수 慶南大學校 附設 工業技術硏究所 2003 硏究論文集 Vol.21 No.2

최근 컴퓨팅 환경이 변화함에 따라 현재 운용되고 있는 레거시 시스템을 객체지향이나 웹 환경과 같은 새로운 환경에서도 운용할 수 있도록 시스템을 현대화하고자 하는 연구가 활발히 진행되고 있다. 특히, 설계 패턴, 프레임워크 등의 소프트웨어 재사용 기술과 함께 컴포넌트 기술이 개발, 보급됨에 따라 레거시 시스템을 컴포넌트로 변환하거나 연계하는 방법들이 연구되고 있다. 본 논문은 IBM 메인 프레임에서 운용되고 있는 CICS 및 SQL 코볼 시스템을 EJB 래퍼 컴포넌트로 연계하는 일련의 프로세스를 지원하는 연계 도구로서 입력된 코볼 소스코드를 어휘분석과 구문분석을 통하여 새로운 형태의 효율적인 트리를 구성한다. 효율적인 트리를 통해서 코볼 소스코드를 객체지향의 컴포넌트로 쉽게 변환할 수 있게 한다. As changing of computer systems, there are many researches about legacy-system available to new environment like object-orient technology or web environment. Specially, many converting or linking method about legacy-system have been studied, because not only software reusing technologies of design-pattern and frameworks but technologies about components are supported. This paper contains the linkage-tool that supports CICS and SQL COBOL system with EJB wrapper components. We also propose an AST-based parser which analysis input COBOL source code, and generates formatted AST tree. COBOL source-code are changed to new formatted efficient tree. From the above AST, we can systemertiaclly convert COBOL legacy systematically into object-oriented componet.

지형학적 인자에 의한 미호천수계의 유황분석

전민우,최동해,조용수 충북대학교 건설기술연구소 2002 建設技術論文集 Vol.21 No.2

The correlation equations were proposed to predict the flow duration of ungaged basin by regression analysis based on geomorphological factors. The proposed correlation equations give good results in consequence of application in Kagyung stream basin and Samki stream basin. Among the flow duration, the correlation coefficient of fruitful water discharge was the smallest value, on the hand, the correlation coefficient of reference low water flow was appeared to be the largest value. The correlation coefficient including only stream slope S as the independent variable was the smallest value, on the other hand, in the case of including basin area A and stream length L or A, L, S as the independent variable the correlation coefficient appeared to be the largest value and in this case, the two correlation coefficient were very close. These proposed correlation equations can be used to grasp the flow duration by acquiring the geomorphological factors of ungaged stream basin.

지역별 건설업 인력수급 현황 분석에 관한 연구

전찬민,전용일,황찬수,박태근 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

In currency crisis(IMF relief loan), the construction industry has prepared a foundation for existence by taking such desperate countermeasure as reducing a lot of construction companies and readjusting the their structure. Even though a number of employee of construction industry came to a million in 1996, it reduced to 980 thousand in 1997 and 710 thousand in 1998. After 1998, there was the trend about reducing a number of employee every year. The final goals of this study have inquired into the current situation of manpower supply and demand per region, compared and analyzed the circumstance of manpower supply and demand, and utilized references in decision-making between construction companies and students.