Endovascular Treatment for Iliac Vein Compression Syndrome: a Comparison between the Presence and Absence of Secondary Thrombosis

Wen-Sheng Lou,Jian-Ping Gu,Xu He,Liang Chen,Hao-Bo Su,Guo-Ping Chen,Jing-Hua Song,Tao Wang 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.2

Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective. Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective.

Development of Sensing Signal Transmission and System in Intelligent Field

( Wen-luh Huang ),( Shu-yu Yang ),( Wen Sheng Chen ),( Yan-ru Huang ),( Yi-chen Wu ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

There is a problem which is large manpower consumption on contract sweet potato field when measure the soil moisture, control weeds, pests and diseases currently. In addition, serious problems of aging and labor shortage are especially troublesome in domestic rural areas. Therefore, we develop a management system combined sensor, single-chip control module and real-time irrigation module to meet the needs. Throughout the wireless signal transmission, the management of operating system with instant control and output data achieves intelligent control. At present, the system has been able to collect moisture data from field and to do the corresponding treatment immediately. At the same time, upload the data to cloud, then we can monitor field in real-time. With the establishment of the database, we have been to achieve long-term or short-term analysis and management. We really hope that the result can enhance the intelligence of agricultural technology, increase farmers profits, sustain development of agriculture and keep competitiveness.

Arm Exoskeleton Rehabilitation Robot with Assistive System for Patient after Stroke

Guan De Lee,Wei-Wen Wang,Kai-Wen Lee,Sheng-Yen Lin,Li-Chen Fu,Jin-Shin Lai,Wen-Shiang Chen,Jer-Junn Luh 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

Exercise dosage is proven to be an important factor in the physical treatment. Robot assistive approach can improve the rehabilitation quality and evaluate patient’s recovery quantitatively. This paper presents kinematic structure, assistive control system, and integrated F/T sensor for an upper limb rehabilitation robot. By using the human arm dynamic, there are three rehabilitation modes presented in this paper: active mode, assistive mode, and passive mode. In assistive mode, we have two strategies to implement it. One is to amplify interactive torque, and the other is to apply assist-as-needed concept. The goal of this mode is to assist patients to finish motion tasks. The rehabilitation robot under investigation has 7 degree of freedom (DOF) actuated by DC motors, which are programmed to drive the robot arm in the 3D space. To validate our control design, some realistic experiments are conducted and its satisfactory performance is demonstrated. This work is approved clinical testing by the Department of Health, Executive Yuan, R.O.C. So far, we are demonstrating the effect of our controller.

Timosaponin B-Ⅱ Inhibits Pro-inflammatory Cytokine Induction by Lipopolysaccharide in BV2 Cells

Wen-Quan Lu,Wan-Sheng Chen,Yan Qiu,Tie-Jun Li,Xia Tao,Lian-Na Sun 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.9

It was reported that the total polysaccharides extracts from Anemarrhenae asphodeloides Bge(Liliaceae, rhizome) could inhibit inflammatory responses in various models. In the present study, the effects of Timosaponin B-II, a purified extract from A. asphodeloidesb, on the expressions of IL-1β, TNF-α and IL-6, the activity of NF-κB and the activation of signal pathway related to NF-κB were explored in vitro. Timosaponin B-Ⅱ significantly attenuated increase of these cytokines on both mRNA and protein levels from LPS-stimulated BV2 cells in a dose-dependent manner. The reporter gene assay also showed that the activation of NF-κB induced by LPS was inhibited by pre-treatment with Timosaponin B-Ⅱ. Moreover, western blot results showed that the activation of p38, JNK and P65 had been decreased. These results suggest that both NF-κB signal pathway and MAPK pathway were involved in the inhibitory effects of Timosaponin B-II on the expression of pro-inflammatory cytokines.

Chatter Analysis and Stability Prediction of Milling Tool Based on Zero-order and Envelope Methods for Real-time Monitoring and Compensation

Wen-Yang Chang,Chung-Cheng Chen,Sheng-Jhih Wu 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.5

The artificial intelligence means that it can autonomously determine the cutting situations regardless any cutting states and change them automatically as required. Regenerative chatter is an instability occurrence during CNC machining operation that must be avoided for high accuracy and greater surface manufactures. In this paper, an artificial intelligence based on zero-order and enveloped method is use for the chatter analysis and stability prediction of milling tool in real-time and on-line compensations. In order to measure the phase shift of harmonic frequency for real-time in cutting process, two three-axis accelerometers are installed at the bottom of the workpiece and at the above of the spindle to collect the vibration signal. Experimental results showed that the phase shift of regenerative chatter is higher than unchartered. The stable chatter signals of time domain vibration according to stability lobe diagram have low amplitude of vibration. This was confirmed that characteristic marks of chatter vibrations have higher amplitude level signal in the experimental test. In addition, this study developed a chatter prediction system for on-line calculation and real-time monitoring and compensation. The modal parameters of the chatter analysis and stability prediction system like natural frequencies, damping, and residues must also be identified automatically.

Effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after oral administration

Chen, Yin Bin,Wang, Yu Fang,Hou, Wei,Wang, Ying Ping,Xiao, Sheng Yuan,Fu, Yang Yang,Wang, Jia,Zheng, Si Wen,Zheng, Pei He The Korean Society of Ginseng 2017 Journal of Ginseng Research Vol.41 No.2

Background: Both ginsenoside Re and B-complex vitamins are widely used as nutritional supplements. They are often taken together so as to fully utilize their antifatigue and refreshing effects, respectively. Whether actually a drug-nutrient interaction exists between ginsenoside Re and B-complex vitamins is still unknown. The objective of this study was to simultaneously investigate the effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after their oral administration. The study results will provide valuable theoretical guidance for the combined utilization of ginseng and B-complex vitamins. Methods: Ginsenoside Re with or without B-complex vitamins was orally administered to mice to evaluate its antifatigue effects and to rats to evaluate its bioavailability. The antifatigue activity was evaluated by the weight-loaded swimming test and biochemical parameters, including hepatic glycogen, plasma urea nitrogen, and blood lactic acid. The concentration of ginsenoside Re in plasma was determined by liquid chromatography-tandem mass spectrometry. Results: No antifatigue effect of ginsenoside Re was noted when ginsenoside Re in combination with B-complex vitamins was orally administered to mice. B-complex vitamins caused to a reduction in the bioavailability of ginsenoside Re with the area under the concentration-time curve from zero to infinity markedly decreasing from $11,830.85{\pm}2,366.47h{\cdot}ng/mL$ to $890.55{\pm}372.94h{\cdot}ng/mL$. Conclusion: The results suggested that there were pharmacokinetic and pharmacodynamic drug-nutrient interactions between ginsenoside Re and B-complex vitamins. B-complex vitamins can significantly weaken the antifatigue effect and decrease the bioavailability of ginsenoside Re when simultaneously administered orally.

Mode identifiability of a cable-stayed bridge under different excitation conditions assessed with an improved algorithm based on stochastic subspace identification

Wen-Hwa Wu,Sheng-Wei Wang,Chien-Chou Chen,Gwolong Lai 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.17 No.3

Deficient modes that cannot be always identified from different sets of measurement data may exist in the application of operational modal analysis such as the stochastic subspace identification techniques in large-scale civil structures. Based on a recent work using the long-term ambient vibration measurements from an instrumented cable-stayed bridge under different wind excitation conditions, a benchmark problem is launched by taking the same bridge as a test bed to further intensify the exploration of mode identifiability. For systematically assessing this benchmark problem, a recently developed SSI algorithm based on an alternative stabilization diagram and a hierarchical sifting process is extended and applied in this research to investigate several sets of known and blind monitoring data. The evaluation of delicately selected cases clearly distinguishes the effect of traffic excitation on the identifiability of the targeted deficient mode from the effect of wind excitation. An additional upper limit for the vertical acceleration amplitude at deck, mainly induced by the passing traffic, is subsequently suggested to supplement the previously determined lower limit for the wind speed. Careful inspection on the shape vector of the deficient mode under different excitation conditions leads to the postulation that this mode is actually induced by the motion of the central tower. The analysis incorporating the tower measurements solidly verifies this postulation by yielding the prevailing components at the tower locations in the extended mode shape vector. Moreover, it is also confirmed that this mode can be stably identified under all the circumstances with the addition of tower measurements. An important lesson learned from this discovery is that the problem of mode identifiability usually comes from the lack of proper measurements at the right locations.

The Pressure Melting of Ice around the Sphere and Cylinder

Wen Zhen Chen,Qiang Sheng Yang 대한기계학회 1998 Heat transter conference Vol.7 No.1

Detoxification, antioxidant, and digestive enzyme activities and gene expression analysis of Lymantria dispar larvae under carvacrol

Chen Yun-ze,Zhang Bo-wen,Yang Jing,Zou Chuan-shan,Li Tao,Zhang Guo-cai,Chen Guang-sheng 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.1

Carvacrol is a terpene compound with various biological activities. However, few studies have specifically focused on its insecticidal activity and mechanism of carvacrol. The larvae of Lymantria dispar are seriously harmful herbivorous insect. This study measured the antifeedant, growth-inhibitory, and toxic effects of carvacrol on L. dispar larvae. To further clarify the insecticidal mechanism of carvacrol, the effects of carvacrol on detoxifying enzymes, antioxidative enzymes, digestive enzyme activities, and the mRNA expression of the abovementioned enzyme genes were investigated. The results of the study showed that the median lethal concentration (LC 50 ) and the sublethal concentration (LC 20 ) of carvacrol were 1.120 mg/mL and 0.297 mg/mL, respectively, at 72 h. After LC 20 treatment of L. dispar larvae for 72 h, food intake and weight gain were significantly lower compared with the control. Enzyme activity assays showed that carvacrol significantly inhibited the activities of carboxylesterase (CarE), glutathione S-transferase (GST), and acetylcholinesterase (AchE), and the inhibition rate of AchE activity was highest (66.51%). Carvacrol also activated the activities of superoxide dismutase (SOD) and catalase (CAT), while it inhibited the activities of lipase (LIP) and amylase (AMS), and first inhibited and then activated protease. In addition, qRT-PCR tests showed that carvacrol affected the mRNA expression levels of CarE, GST, AchE, SOD, CAT, LIP, AMS, and protease. This study helps to clarify the insecticidal mechanism of carvacrol on L. dispar larvae.

ENHANCED BIODEGRADATION OF NITROGENOUS COMPOUNDS IN ABS - RESIN MANUFACTURING WASTEWATER USING ANOXIC DENITRIFICATION AND OXIC NITRIFICATION TREATMENT PROCESS

( Sheng Shung Cheng,Wen Chin Chen,Jin Chuang Chiou ) 한국물환경학회 1997 제6차 국제수질보전학회 아시아 태평양지역 학술회의 Vol.1 No.-