Review on State of Charge Estimation Methods for Li-Ion Batteries

Xiaoqiang Zhang,Wei-ping Zhang,Hongyu Li,Mao Zhang 한국전기전자재료학회 2017 Transactions on Electrical and Electronic Material Vol.18 No.3

The state of charge (SOC) is an important parameter in a battery-management system (BMS), and is very significantfor accurately estimating the SOC of a battery. Li-ion batteries boast of excellent performance, and can only remainat their best working state by means of accurate SOC estimation that gives full play to their performances and raisestheir economic benefits. This paper summarizes some measures taken in SOC estimation, including the dischargeexperiment method, the ampere-hour integral method, the open circuit voltage method, the Kalman filter method,the neural network method, and electrochemical impedance spectroscopy (EIS. The principles of the various SOCestimation methods are introduced, and their advantages and disadvantages, as well as the working conditionsadopted during these methods, are discussed and analyzed.

Investigation of the Phenomenon of Propagated Sensation along the Channels in the Upper Limb Following Administration of Acupuncture and Mock Laser

Shohreh Razavy,Marcus Gadau,Shi Ping Zhang,Fu Chun Wang,Sergio Bangrazi,Christine Berle,Mahrita Harahap,Tie Li,Wei Hong Li,Christopher Zaslawski 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.5

Background: Similar to De Qi psychophysical responses, propagated sensation along the channels (PSC) is considered an important phenomenon in traditional Chinese acupuncture. In acupuncture clinical trials, different acupuncture manipulation techniques are used to enhance the propagation of sensation along the channels to facilitate an optimum therapeutic result. Aim: To examine and compare the PSC reported by participants in a clinical trial following the administration of acupuncture and inactive mock laser. Methods: The study was embedded in a two-arm parallel design multicenter, randomized clinical trial, the Tennis Elbow AcupuncturedInternational StudydChina, Hong Kong, Australia, Italy (TEA IS CHAI). Needle sensations were measured using a validated instrument, the Massachusetts General Hospital Acupuncture Sensation Spreading Scale. Ninety-six participants with lateral elbow pain were randomly allocated into two groups in a 1:1 ratio; the acupuncture treatment group (n Z 47) and the mock laser control group (n Z 49). Participants in both groups received the intervention at two acupoints, LI10 and LI11, consisting of 2 minutes of either standardized needle manipulation or mock laser at each acupoint with a rest period between each intervention period. Data were collected immediately following the interventions at the first and the ninth session within the clinical trial. Results: Although participants in both groups perceived PSC radiating to similar sites along the upper limb, the frequency of the reported radiation sites among the two intervention groups for both radiation up the limb (p < 0.05) and radiation down the limb (p < 0.001) were statistically significantly different. Among the radiating sensation sites recorded within the two study groups, the sensations were reported as radiating a greater distance down the forearm to the wrist compared to up the arm. Evaluation of PSC across the four study sites revealed a statistically significant difference in frequency of the reported radiation down the limb sites in each study group and radiation up the limb sites only in control group only (p < 0.001). Conclusion: The findings of the study demonstrated that the PSC phenomenon is not just associated with needling but can be perceived when using a mock laser. Trial registration: Australian and New Zealand Clinical Trial Registry reference: ACTRN12613001138774 on 11th of October 2013.

Predictive value of preoperative lymphocyte-to-monocyte ratio for patients with upper tract urothelial carcinoma

Li, Tao,Xu, Hang,Yang, Lu,Tan, Ping,Wei, Qiang Elsevier 2019 Clinica chimica acta Vol.492 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>To determine the predictive value of preoperative lymphocyte-to-monocyte ratio (LMR) for pathological and survival outcomes in upper tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU).</P> <P><B>Methods</B></P> <P>This retrospective study included 704 UTUC patients between 2008 and 2017. We used a cutoff LMR of 3.6 to evaluate its relationship with oncological outcomes after RNU, using the Kaplan–Meier method and logistic regression models.</P> <P><B>Results</B></P> <P>During median follow-up of 39 months, decreased preoperative LMR was an independent predictor of poor pathological outcomes. Kaplan–Meier analysis revealed that patients with low LMR (<3.6) had poor cancer-specific survival (CSS), recurrence-free survival (RFS), and overall survival (OS); this prognostic value was ascertained for patients with high pathological grade and more advanced stage UTUC, but not for patients with low pathological features. Multivariate Cox proportional hazards model revealed that low LMR was an independent predictor of poor CSS, RFS and OS [hazard ratio (HR) = 1.42, <I>P</I> = 0.02; HR = 1.39, <I>P</I> = 0.008; HR = 1.38, <I>P</I> = 0.017, respectively].</P> <P><B>Conclusion</B></P> <P>Preoperative low LMR was an independent predictor of poor pathological and oncological outcomes of UTUC after RNU. Subgroup analysis confirmed that the prognostic value of LMR was confined to patients with a high pathological grade and more advanced stage tumor.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Preoperative low lymphocyte-to-monocyte ratio (LMR) predicts worse pathologic result for upper tract urothelial carcinoma (UTUC) patients after radical nephroureterectomy (RNU). </LI> <LI> Preoperative low LMR is associated with poor clinical outcomes for UTUC patients after RUN. </LI> <LI> Preoperative low LMR exert a prognostic value mainly for UTUC patient with high pathologic grade and stage tumor. </LI> </UL> </P>

Expression of Proteasome Activator REGγ in Human Laryngeal Carcinoma and Associations with Tumor Suppressor Proteins

Li, Li-Ping,Cheng, Wei-Bo,Li, Hong,Li, Wen,Yang, Hui,Wen, Ding-Hou,Tang, Yue-Di Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

The functional significance of the proteasome activator $REG{\gamma}$ in the regulation of cell proliferation and apoptosis has been recognized. However, pathological contributions to tumor development remain to be elucidated. Both oncogenic proteins and tumor suppressors are targeted by $REG{\gamma}$ for proteasomal degradation. It has been proposed that the role of the $REG{\gamma}$ in the pathogenesis of cancer is cell- and context-specific. In this study, we aimed to explore the potential involvement of $REG{\gamma}$ in laryngeal carcinomas, comparing protein expression in tumor and adjacent tissues by immunohistochemical staining and Western blot analysis. We also characterized the correlation between the expression of $REG{\gamma}$ and the previously identified substrates p53 and p21. We showed that $REG{\gamma}$ was abnormally highly expressed in cancer tissues. Statistical analysis revealed that there was a positive relationship between the level of $REG{\gamma}$ and the expression of p53 and p21. Our study suggests that $REG{\gamma}$ overexpression can facilitate the growth of laryngeal cancer cells.

Cordycepin protects against β–amyloid and ibotenic acid– induced hippocampal CA1 pyramidal neuronal hyperactivity

Li-Hua Yao,Jinxiu Wang,Chao Liu,Shanshan Wei,Guoyin Li,Songhua Wang,Wei Meng,Zhi-Bin Liu,Li-Ping Huang 대한약리학회 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.6

Cordycepin exerts neuroprotective effects against excitotoxic neuronal death. However, its direct electrophysiological evidence in Alzheimer’s disease (AD) remains unclear. This study aimed to explore the electrophysiological mechanisms underlying the protective effect of cordycepin against the excitotoxic neuronal insult in AD using whole-cell patch clamp techniques. β-Amyloid (Aβ) and ibotenic acid (IBO)–induced injury model in cultured hippocampal neurons was used for the purpose. The results revealed that cordycepin significantly delayed Aβ + IBO–induced excessive neuronal membrane depolarization. It increased the onset time/latency, extended the duration, and reduced the slope in both slow and rapid depolarization. Additionally, cordycepin reversed the neuronal hyperactivity in Aβ + IBO–induced evoked action potential (AP) firing, including increase in repetitive firing frequency, shortening of evoked AP latency, decrease in the amplitude of fast afterhyperpolarization, and increase in membrane depolarization. Further, the suppressive effect of cordycepin against Aβ + IBO–induced excessive neuronal membrane depolarization and neuronal hyperactivity was blocked by DPCPX (8-cyclopentyl-1,3-dipropylxanthine, an adenosine A1 receptor–specific blocker). Collectively, these results revealed the suppressive effect of cordycepin against the Aβ + IBO–induced excitotoxic neuronal insult by attenuating excessive neuronal activity and membrane depolarization, and the mechanism through the activation of A1R is strongly recommended, thus highlighting the therapeutic potential of cordycepin in AD.

Technical Note : The FasT-Fix Repair Technique for Ramp Lesion of the Medial Meniscus

( Wei Ping Li ),( Zhong Chen ),( Bin Song ),( Rui Yang ),( Wei Quan Tan ) 대한슬관절학회 2015 대한슬관절학회지 Vol.27 No.1

Introduction: This technical note describes a new arthroscopic technique to repair the peripheral attachment lesion of the posterior horn of the medial meniscus. The operation was performed under arthroscopy using a standard anterior portal. Surgical Technique: A FasT-Fix needle was inserted obliquely close to the tibial plateau and the first implant was inserted into the joint capsule depending on its bending angle underneath the meniscus. The second implant was inserted through 1/3 periphery of the meniscus into the meniscocapsular area. The pre-tied self-sliding knot was tensioned to achieve secure fixation of the posterior meniscal peripheral attachment at the original attachment point. Materials and Methods: From August 2011 to February 2014, 23 knees were diagnosed as ramp lesion, underwent meniscal repair using FasT-Fix technique. Results: All patients were followed up for average 14 months. The Lysholm score improved from preoperative 64.4±4.52 to postoperative 91.2±4.60. Conclusions: We believe that the FasT-Fix technique via the standard anterior portal can be a more convenient and less traumatic alternative for repair of the peripheral attachment lesion of the posterior horn of the medial meniscus in the anterior cruciate ligament deficient knee.

Study on mechanism of macro failure and micro fracture of local nearly horizontal stratum in super-large section and deep buried tunnel

Li, Shu-cai,Wang, Jian-hua,Chen, Wei-zhong,Li, Li-ping,Zhang, Qian-qing,He, Peng Techno-Press 2016 Geomechanics & engineering Vol.11 No.2

The stability of surrounding rock will be poor when the tunnel is excavated through nearly horizontal stratum. In this paper, the instability mechanism of local nearly horizontal stratum in super-large section and deep buried tunnel is revealed by the analysis of the macro failure and micro fracture. A structural model is proposed to explain the mechanics of surrounding rock collapse under the action of stress redistribution and shed light on the macroscopic analytical approach of the stability of surrounding rock. Then, some highly effective formulas applied in the tunnel engineering are developed according to the theory of mixed-mode micro fracture. And well-documented field case is made to demonstrate the effectiveness and accuracy of the proposed analytical methods of mixed-mode fracture. Meanwhile, in order to make the more accurate judgment about yield failure of rock mass, a series of comprehensive failure criteria are formed. In addition, the relationship between the nonlinear failure criterion and $K_I$ and $K_{II}$ of micro fracture is established to make the surrounding rock failure criterion more comprehensive and accurate. Further, the influence of the parameters related to the tension-shear mixed-mode fracture and compression-shear mixed-mode fracture on the propagation of rock crack is analyzed. Results show that ${\sigma}_3$ changes linearly with the change of ${\sigma}_1$. And the change rate is related to ${\beta}$, angle between the cracks and ${\sigma}_1$. The proposed simple analytical approach is economical and efficient, and suitable for the analysis of local nearly horizontal stratum in super-large section and deep buried tunnel.

Structural instantaneous frequency extraction based on improved multi-synchrosqueezing generalized S-transform

Ping-Ping Yuan,Xue-Li Cheng,Hang-Hang Wang,Jian Zhang,Zhong-Xiang Shen,Wei-Xin Ren 국제구조공학회 2021 Smart Structures and Systems, An International Jou Vol.28 No.5

A new method is proposed to improve the accuracy of structural instantaneous frequency (IF) extraction. The proposed method combines a new form of improved generalized S-transform (IGST) and a multi-synchrosqueezing operation. The parameters selection of the window function in IGST is derived through the concentration measure (CM) principle. Then, the multi-synchrosqueezing algorithm is employed to improve energy aggregation of time-frequency analysis (TFA). To verify the effectiveness and accuracy of the proposed improved multi-synchrosqueezing generalized S-transform (IMSSGST), a frequency-modulated multi-component signal is investigated. For structural IF extraction, a two-story shear frame and a threestory steel frame structure are introduced. Furthermore, the IF identification of a seven-story RC shear wall structure is conducted to verified the practicability in actual engineering. Numerical simulation and experimental results show that the proposed method can effectively improve the energy aggregation of TFA and effectively improve the accuracy of IF identification.

No Association Between the USP7 Gene Polymorphisms and Colorectal Cancer in the Chinese Han Population

Li, Xin,Wang, Yang,Li, Xing-Wang,Liu, Bao-Cheng,Zhao, Qing-Zhu,Li, Wei-Dong,Chen, Shi-Qing,Huang, Xiao-Ye,Yang, Feng-Ping,Wang, Quan,Wang, Jin-Fen,Xiao, Yan-Zeng,Xu, Yi-Feng,Feng, Guo-Yin,Peng, Zhi-Ha Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

A clinical Comparison of Lobaplatin or Cisplatin with Mitomycine and Vincristine in Treating Patients with Cervical Squamous Carcinoma

Li, Wei-Ping,Liu, Hui,Chen, Li,Yao, Yuan-Qing,Zhao, En-Feng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

Background: The research was to compare the efficacy and side effects of cisplatin or lobaplatin in combination with mitomycine (MMC) and vincristine in treating patients with cervical squamous carcinoma. Materials and Methods: Cervical squamous carcinoma patients who were pathologically diagnosed with stage Ib-IIb from April 2012 to May 2013 in the general hospital of Chinese People's Libration Amy were enrolled. All patients were confirmed without prior treatment and were randomly divided into two groups, Group A and B. Efficacy and side effects were evaluated after one cycle of chemotherapy. Results: Group A (n=42) were treated with Loubo$^{(R)}$ (Lobaplatin) $50mg/m^2$, MMC $16mg/m^2$ and Vincristine $2mg/m^2$ every 21 days. Group B (n=44) were treated with Cisplatin $100mg/m^2$, MMC $16mg/m^2$ and Vincristine $2mg/m^2$ every 21 days. All 86 patients completed one cycle of chemotherapy with cisplatin or lobaplatin in combination with MMC and vincristine. No difference was observed regardiing short-term effect between two groups. Main side effects were bone marrow suppression and gastrointestinal reactions including decrease of white blood cells, platelet and nausea/vomiting. Grade III-VI liver and kidney impairment was not reported in two groups. In group A the incidence of uterine artery spasm in the process of drug delivery was significantly lower than the group B. Conclusions: Cisplatin or lobaplatin with MMC and Vincristine in the interventional treatment of cervical squamous carcinoma were effective, especially after uterine artery perfusion chemotherapy at tumor reduction and tumor downstaging period. The adverse reactions of concurrent chemotherapy are tolerable, and low physical and mental pressure even more less stimulation of vascular in treatment with lobaplatin. However, the long-term effects of this treatment need further observation.