정신분열병 환자에서 얼굴 영상의 작동기억 장애 : 기능자기공명영상연구

이창욱,김태석,주라형,박주미,박여진,김종진,전신수,배치운,김정진,이수정,이철,백인호 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Objectives : Impaired processing of facial information is one of the broad ranges of cognitive deficits seen in patients with Schi-zophrenia. We aimed to elucidate the differences in brain activities involved in the process of facial working memory between schizophrenic patients and healthy comparison subjects. Methods : Twelve patients with schizophrenia were recruited along with twelve demographically matched healthy volunteers as a comparison group. Functional magnetic resonance imaging (fMRI) was used to assess cortical activities during the Perfor-mance of a 2-back working memory paradigm using images of neutral faces as mnemonic content. Rcsults : The patient group performed the tasks with reduced accuracy. Group analysis revealed that the left fusiform gyrus, the right superior frontal gyrus, the bilateral middle frontal gyri/insula, the left middle temporal gyrus, the precuneus, the quadrangular lobules and the vermis of cerebellum showed decreased cortical activities in the patient group. On the other hand, an increased level of activation in the lateral prefrontal cortex and the pahetal lobule was observed from the patient group, all in the right hemisphere. Conulusion : A decreased level of activity in the left fusiform gyrus among the patient group implicates inefficient processing of facial information. An increased level of activation in prefrontal and parietal neural networks from the patient group confirms earlier findings on the impaired working memory of patients with schizophrenia.

Hepatoma cell에 증식억제작용을 나타내는 식물들

이은주,정용자 慶星大學校 1998 論文集 Vol.19 No.1

We have studied that the effect on the inhibition of the cancer cell growth by the 3-[4,5-Dime wthylthiazol-2 yl]-2,5-diphenyl-tetrazolium bromide(MTT) assay, to investigate the anticancer effect with plants, observed around us, by culturing the human hepatoma cell-line. And we knew it was the best condition that the cell number was 4×10³ cells/well and the time of culture is 48 hours. We found that Equisetum arvense L. and Lactuca dentata Makino. var. Flaviflora Makino. exhibited a good anticancer effect and especially Capsicum annum L. angulosum Mill exhibited the best effect of them.

수종 생약의 Hepatoma cell line에 미치는 형태적 변화의 동정

이은주,정용자 慶星大學校 1998 論文集 Vol.19 No.2

The cells included in medium were invastigated to be aggregated and destroyed slowly by treatment with Lactuca dentata Makino. var. flaviflora Makino. On the other hand, the cells treated with Equisetum arvense L were aggregated to be coat-like. The case of Capsicum annuum L. var. angulosum Mill, the cells became vague after 2 days and then destroyed. This procedure was faster than other. The chromasome was more condensated after 37hr treated with Capsicum annuum L. var. angulosum Mill.

근전도 바이오피이드백을 이용한 불안장애 환자 및 정상인의 근육긴장도에 관한 비교연구

정도언,이주호 大韓神經精神醫學會 1987 신경정신의학 Vol.26 No.2

For the purpose of comparing muscle tension level and muscle relaxibility between anxiety disorder patients and normal controls, frontalis EMG levels of 28 anxiety disorder patients (male 14, female 14) and 40 normal controls (male 22, female 18)were measured. The results were as follows: 1) The mean value of EMG basal levels of the anxiety disorder group were 2.38㎶ for male and 2.89㎶ for female, which did not prove to be significantly different from those in the control group (1.77㎶ for male and 3.17㎶ for female). 2) In both male and female groups, anxiety disorder patients and normal controls were significantly different from each other in the mean EMG level on relaxation trial and this was consistent with the findings by the analysis of covariance. The result suggested that muscle relaxibility of the anxiety disorder group was significantly lower than that of the normal control group. 3) In 36% of anxiety disorder patient, paradoxical rise of the muscle tension above the basal(resting) level was noted on relaxation trial.

MCF-7에 미치는 인근식물들의 항암효과 Screening Test

곽수영,이은주,정용자 慶星大學校 1998 論文集 Vol.19 No.1

We have studied that the effect on the inhibition of the cancer cell growth by the 3-[4,5-Dimewthylthiazol-2 yl]-2,5-diphenyl-tetrazolium bromide(MTT) assay, to investigate the anticancer effect with plants, observed around us, by culturing the human MCF-7 mammary gland adenocarcinoma cell-line. And we knew it was the best condition that the cell number was 4×10³ cells/well and the time of culture is 48hours. We observed the effect on the inhibition of the cuncer cell growth with plants, observed us and we can find that Capsicum annum L. angulosum Mill exhibited a good anticancer effect.

질소산화물의 급성 노출로 인한 폐 손상 1례

김정호,김대환,손병철,이창희,김정원,문덕환,이채언,김주인 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Lung injuries due to exposure to nitrogen oxides can occur in various process in industry. We experienced a case of chemical pneumonitis induced by accidental inhalation of nitrogen oxides emitted from the bath in an acid dipping operation. Case : Dyspnea, cough and blood-tinged sputum production, cyanosis, and tachypnea occurred after exposure to oxides of nitrogen. There were bilateral diffuse ground glass opacities in simple chest radiography and high resolutional computed tomography, hypoxemia in arterial blood gas analysis, mixed ventilation defect and reduced diffusion capacity in spirometry. As an oxygen and supportive therapy, after hospitalization, was given, the patient recovered completely from the lung injury on the 8th day after admission. There was no evidence of delayed onset of bronchiolitis obliterance or pulmonary edema in a follow-up for about 6 months. Conclusions : Acid dip operation require more efficient hooding and exhausting system for the prevention of lung injuries caused by inhalation of nitrogen oxides. Also health education for worker need.

The Regulator RamA Influences cmytA Transcription and Cell Morphology of Corynebacterium ammoniagenes

Lee, Seok-Myung,Lee, Joo-Young,Park, Kwang-Jin,Park, Jun-Sung,Ha, Un-Hwan,Kim, Younhee,Lee, Heung-Shick Springer-Verlag 2010 Current microbiology Vol.61 No.2

Differences in pregnancy outcomes, prenatal care utilization, and maternal complications between teenagers and adult women in Korea : A nationwide epidemiological study

Lee, Sang Hyung,Lee, Seung Mi,Lim, Nam Gu,Kim, Hyun Joo,Bae, Sung-Hee,Ock, Minsu,Kim, Un-Na,Lee, Jin Yong,Jo, Min-Woo Wolters Kluwer Health 2016 Medicine Vol.95 No.34

<P><B>Abstract</B></P><P>Teenage mothers are at high risk for maternal and neonatal complications. This study aimed to evaluate the socioeconomic circumstances of teenage pregnancy, and determine whether these increased risks remained after adjustment for socioeconomic circumstances in Korea. Using the National Health Insurance Corporation database, we selected women who terminated pregnancy, by delivery or abortion, from January 1, 2010 to December 31, 2010. Abortion, delivery type, and maternal complications were defined based on the International Classification of Diseases-10th Revision. We compared teenagers (13–19 years at the time of pregnancy termination) with other age groups and investigated differences based on socioeconomic status, reflected by Medical Aid (MA) and National Health Insurance (NHI) beneficiaries. We used multivariate analysis to define the factors associated with preterm delivery. Among 463,847 pregnancies, 2267 (0.49%) involved teenagers. Teenage mothers were more likely to have an abortion (33.4%) than deliver a baby when compared with other age groups (20.8%; <I>P</I> < 0.001). About 14.4% of teenage mothers had never received prenatal care throughout pregnancy. Among teenage mothers, 61.7% of MA recipients made fewer than 4 prenatal care visits (vs 38.8% of NHI beneficiaries) (<I>P</I> < 0.001). Teenage mothers more often experienced preterm delivery and perineal laceration (<I>P</I> < 0.001). Teenage mothers (<20 years) were 2.47 times more likely to have preterm delivery than older mothers (20–34 years; <I>P</I> < 0.001). Teenage mothers had higher risk of inadequate prenatal care and subsequently of preterm delivery, which remained significantly higher after adjusting for socioeconomic confounding variables and adequacy of prenatal care in Korean teenagers (<I>P</I> < 0.001).</P>

Clinical Characteristics and Effects of Steroid Therapy in Children with Acute Cerebellar Ataxia

Joo Young Lee,Ja Un Moon,Da Hye Yoon,Ji Yoon Han,In Goo Lee 대한소아신경학회 2021 대한소아신경학회지 Vol.29 No.3

Purpose: Acute cerebellar ataxia (ACA) is characterized by unsteady gait and instability of the trunk, and is caused by secondary autoimmune responses to infection or vaccination in healthy children. Although its prognosis is usually very good, full symptom recovery generally takes 2 to 3 months. This study aimed to investigate clinical symptoms, neuroimaging findings, and laboratory findings in children with ACA, and to evaluate the effects of steroid therapy on ACA according to the method of administration (intravenous methylprednisolone vs. oral prednisolone). Methods: We retrospectively analyzed nine patients diagnosed with ACA or acute cerebellitis (AC) who received steroid therapy. Results: Nine children were included in this study (mean age, 3.71±2.89 years). The mean dura-tion between prodromal febrile illness and cerebellar symptoms was 9.63±4.66 days. Ataxia (limb and/or truncal) was the most common cerebellar sign. Steroids were administered in two ways: methylprednisolone (20 to 30 mg/kg/day) was changed to an oral steroid (prednisolone, 1 mg/kg/ day) after 2 to 3 days of administration; an oral steroid was used from the beginning of treat-ment. The cerebellar symptoms began to improve within 2 to 4 days of steroid therapy. All pa￾tients fully recovered without sequelae. The mean interval until full recovery of the cerebellar symptoms was 28.0±19.3 days, and was not significantly different between patients who re-ceived an oral steroid after methylprednisolone pulse therapy and patients who only received an oral steroid (P>0.05). Conclusion: Regardless of the method of drug administration, steroid therapy helps to improve cerebellar symptoms in children with ACA/AC.

A Packet Scheduling for Input-Queued Router with Deadline Constraints

Un Gi Joo,Heyung Sub Lee,Hyeong Ho Lee,Whan Wo Kim 대한전자공학회 2002 ITC-CSCC :International Technical Conference on Ci Vol.2002 No.7