Numerical study on effect of corrugated diathermal partition on natural convection in a square porous cavity

Jayesh Subhash Chordiya,Ram Vinoy Sharma 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.5

Partitions in porous enclosure have been observed to offer a key solution for reduction of heat transfer rate across it. However, very little is known about the effect of its shape, position and orientation within the porous enclosure, which seems to be an important consideration for thermal designers. The present numerical investigation reports the effect of a corrugated diathermal partition within a fluid saturated porous enclosure. The objective is to comprehend the effect of the amplitude of the corrugated partition (0.05 ≤ A ≤ 0.25) and position of the partition (0.2 ≤ D ≤ 0.8) for various values of Darcy-modified Rayleigh number (10 ≤ Ra ≤ 1000) on natural convection fluid flow and heat transfer. An overall II-order finite difference method has been used to solve the Darcy model for porous media using successive accelerated replacement scheme. It is found that value of amplitude for which the least value of Nusselt number is obtained shifts to a lower side as value of modified Rayleigh number increases i.e., amplitude decreases from 0.16 to 0.025 as Ra changes from 100 to 1000. For higher values of Rayleigh number, the reduction in Nusselt number is about 61% with respect to porous enclosure without partition, which is very substantial.

A case of histoplasmosis in a patient with MDS/MPN-U

Pulkit Rastogi,Prashant Sharma,Narender Kumar,Shivaprakash M. Rudramurthy,Neelam Varma,Subhash Varma 대한혈액학회 2016 Blood Research Vol.51 No.3

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A case of histoplasmosis in a patient with MDS/MPN-U

Pulkit Rastogi,Prashant Sharma,Narender Kumar,Shivaprakash M. Rudramurthy,Neelam Varma,Subhash Varma 대한혈액학회 2016 Blood Research Vol.51 No.3

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Economic Integration in Latin America

( Hem C Basnet ),( Subhash C Sharma ) 세종대학교 경제통합연구소 2013 Journal of Economic Integration Vol.28 No.4

This study examines the feasibility of economic integration in Latin America. We analyze the existence of the long-term and short-term common movements among key macro variables-real GDP, intra-regional trade, private investment and consumption-in the seven largest economies in Latin America-Argentina, Brazil, Chile, Colombia, Mexico, Peru and Venezuela. The joint behavior of the long term trends and the joint response to transitory shocks suggest a significant degree of economic synchronization among these countries. Our results reveal that the economic fluctuations in these countries follow a similar pattern in terms of duration, intensity, response, and timing both in the long run and in the short run. The findings suggest that the group of seven economies in Latin America can lead the path of integration in the region more smoothly as macroeconomic conditions are favorable for them to do so.

Comparative Evaluation of Two-dimensional Radiography and Three Dimensional Computed Tomography Based Dose-volume Parameters for High-dose-rate Intracavitary Brachytherapy of Cervical Cancer: A Prospective Study

Madan, Renu,Pathy, Sushmita,Subramani, Vellaiyan,Sharma, Seema,Mohanti, Bidhu Kalyan,Chander, Subhash,Thulkar, Sanjay,Kumar, Lalit,Dadhwal, Vatsla Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

Background: Dosimetric comparison of two dimensional (2D) radiography and three-dimensional computed tomography (3D-CT) based dose distributions with high-dose-rate (HDR) intracavitry radiotherapy (ICRT) for carcinoma cervix, in terms of target coverage and doses to bladder and rectum. Materials and Methods: Sixty four sessions of HDR ICRT were performed in 22 patients. External beam radiotherapy to pelvis at a dose of 50 Gray in 27 fractions followed by HDR ICRT, 21 Grays to point A in 3 sessions, one week apart was planned. All patients underwent 2D-orthogonal and 3D-CT simulation for each session. Treatment plans were generated using 2D-orthogonal images and dose prescription was made at point A. 3D plans were generated using 3D-CT images after delineating target volume and organs at risk. Comparative evaluation of 2D and 3D treatment planning was made for each session in terms of target coverage (dose received by 90%, 95% and 100% of the target volume: D90, D95 and D100 respectively) and doses to bladder and rectum: ICRU-38 bladder and rectum point dose in 2D planning and dose to 0.1cc, 1cc, 2cc, 5cc, and 10cc of bladder and rectum in 3D planning. Results: Mean doses received by 100% and 90% of the target volume were $4.24{\pm}0.63$ and $4.9{\pm}0.56$ Gy respectively. Doses received by 0.1cc, 1cc and 2cc volume of bladder were $2.88{\pm}0.72$, $2.5{\pm}0.65$ and $2.2{\pm}0.57$ times more than the ICRU bladder reference point. Similarly, doses received by 0.1cc, 1cc and 2cc of rectum were $1.80{\pm}0.5$, $1.48{\pm}0.41$ and $1.35{\pm}0.37$ times higher than ICRU rectal reference point. Conclusions: Dosimetric comparative evaluation of 2D and 3D CT based treatment planning for the same brachytherapy session demonstrates underestimation of OAR doses and overestimation of target coverage in 2D treatment planning.

Magnetic behaviour of nanocrystalline Ni–Cu ferrite and the effect of irradiation by 100 MeV Ni ions

S.N. Dolia,Ravi Kumar,S.K. Sharma,M.P. Sharma,Subhash Chander,M. Singh 한국물리학회 2008 Current Applied Physics Vol.8 No.5

The effects of 100 MeV Ni ion irradiation on magnetic properties of nanoparticles of Ni0.8Cu0.₂Fe₂O₄ with average particle sizes of 40Å and 60Å , synthesized by chemical co-precipitation method have been studied. The spinel cubic structures were confirmed by XRD. The average particle size estimated by XRD and by Langevin function fitting are in good agreement for both the pristine and irradiated samples. The blocking temperature increases with particle size and does not change after irradiation. On irradiation by 100 MeV Ni ions, significant changes in the hysteresis loop features are observed, which may be attributed to formation of cluster of defects in the nanocrystalline samples due to swift heavy ion (SHI) irradiation. It is also found that SHI irradiation produces more dominant changes in the hysteresis loop of smaller particle size of 40Å as compared to that of 60Å. The effects of 100 MeV Ni ion irradiation on magnetic properties of nanoparticles of Ni0.8Cu0.₂Fe₂O₄ with average particle sizes of 40Å and 60Å , synthesized by chemical co-precipitation method have been studied. The spinel cubic structures were confirmed by XRD. The average particle size estimated by XRD and by Langevin function fitting are in good agreement for both the pristine and irradiated samples. The blocking temperature increases with particle size and does not change after irradiation. On irradiation by 100 MeV Ni ions, significant changes in the hysteresis loop features are observed, which may be attributed to formation of cluster of defects in the nanocrystalline samples due to swift heavy ion (SHI) irradiation. It is also found that SHI irradiation produces more dominant changes in the hysteresis loop of smaller particle size of 40Å as compared to that of 60Å.

Primary pyomyositis in North India: a clinical, microbiological, and outcome study

( Susheel Kumar ),( Ashish Bhalla ),( Rajveer Singh ),( Navneet Sharma ),( Aman Sharma ),( Vikas Gautam ),( Surjit Singh ),( Subhash Varma ) 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.2

Background/Aims: Pyomyositis is an infective condition with primary involvement of the skeletal muscles. There is sparse recent literature on patients with pyomyositis. Methods: This study was carried out at emergency services of a tertiary care center located in subtropical area of Indian subcontinent. Results: Sixty-two patients of primary pyomyositis formed the study cohort. Mean age of occurrence was 29.9 ± 14.8 years. There were 54 men. Twelve patients had underlying medical diseases. Muscle pain was seen in all 62 patients. Forty-eight patients (77.4%) had the fever. Most common site of involvement was thigh muscles (n = 29, 46.8%). Forty-nine patients (79%) presented in the suppurative stage of illness. Patients with comorbidities were older (age: median 36 years [interquartile range (IQR), 25 to 47] vs. 24 years [IQR, 16 to 35], p = 0.024), had higher culture positivity with gram-negative organisms (8/9 [88.89%] vs. 6/29 [20.69%], p = 0.001). Importantly, higher number of these patients received inappropriate antibiotics initially. Patients with positive pus culture result had higher complication rate (32/38 [84.21%] vs. 10/18 [55.56%], p = 0.044). Six patients (9.7%) had in-hospital mortality. Lower first-day serum albumin, initial inappropriate antibiotic therapy, and advanced form of the disease at presentation were associated with increased in-hospital mortality. Conclusions: Primary pyomyositis is not an uncommon disease entity. Patients with comorbidities were more likely to receive initial inappropriate antibiotic therapy. Patients with positive pus culture report had the higher rate of complications. Lower first-day serum albumin, initial inappropriate antibiotic therapy and advanced form of the disease at presentation were associated with increased in-hospital mortality.

Quality of Life of Patients with Advanced Cervical Cancer before and after Chemo-radiotherapy

Dahiya, Neha,Acharya, Anita S,Bachani, Damodar,Sharma, DN,Gupta, Subhash,Haresh, KP,Rath, GK Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.7

Background: Cervical cancer is the most frequently diagnosed cancer among women in India. Understanding quality of life (QOL) in women undergoing chemo-radiotherapy for cervical cancer will help in introducing interventions for better care and outcomes in these women. This study assessed QOL before and after chemo-radiotherapy in cervical cancer patients. Materials and Methods: This follow-up study covered sixty-seven newly diagnosed women with advanced cervical cancer (stages 2b to 4b). Structured questionnaires (the European Organization for Research and Treatment of Cancer, EORTC QLQ-C30 and EORTC QLQ-CX24) were used to assess the change in QOL after 6 months of treatment. Results: The mean age of women at the time of detection of cervical cancer was $52.3{\pm}11.29$ years (Range 30-75 years). Six months survival was 92.53%. The mean global health score of cervical cancer patients after six months of treatment was 59.52, which was significantly higher than the pre-treatment score of 50.15 (p=0.00007). Physical, cognitive and emotional functioning improved significantly (p<0.05) after treatment. Fatigue, pain, insomnia and appetite loss improved but episodes of diarrhea increased after treatment. The mean "symptoms score" using EORTC QLQ-CX24 post treatment was 20.0 which was significantly lower as compared to the pre- treatment score 30.0 (p<0.00001). Sexual enjoyment and sexual functioning decreased significantly after treatment. Conclusions: QOL of newly diagnosed cervical cancer patients improved significantly following chemo-radio therapy. Enhancement was also demonstrated on three of the five functional scales of EORTC QLQ-C30. To further improve QOL, interventions focusing on social and psychological support and physical rehabilitation may be needed.

In situ soft templated synthesis of polyfluorene-molybdenum oxide (PF-MoO3) nanocomposite: A nanostructure glucose sensor

Bhagyashri Bajirao Kamble,Paurnima Talele,Anita Kundlik Tawade,Kirankumar Kakchingtabam Sharma,Sawanta Subhash Mali,홍창국,Shivaji Nemchand Tayade 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.6

A polyfluorene-molybdenum oxide nanocomposite (PF-MoO3) was successfully prepared in swollen liquidcrystalline (SLC) lamellar phase. The morphology, shape, and structure of the nanocomposite are characterized by fieldemission scanning electron microscopy (FESEM), X-ray powder diffraction (XRD), and Fourier transform infrared spectroscopy(FTIR). The obtained PF-MoO3 material was loaded over a glassy carbon electrode (GCE). The PF-MoO3/GCEwas employed as a working electrode for the detection of glucose by differential pulse voltammetry (DPV) and cyclicvoltammetry (CV) techniques. The determined limits of detection (LOD) and the limits of quantification (LOQ) fromCV were 7.90×105 M and 2.63×105 M, respectively. The calculated sensitivity of the PF-MoO3 electrode material forglucose was estimated to be 4.29×104A L mol1 cm2. The values of LOD and LOQ obtained from DPV data were7.05×105 M and 2.35×105 M, respectively. The results were in agreement with CV observations. Similarly, the glucosesensitivity for the PF-MoO3/GCE by DPV technique was 5.18×103A L mol1 cm2. In this research, we have developeda highly sensitive glucose sensor by modification of the GCE electrode surface with PF-MoO3 nanocomposite.

Plasma cell leukemia in North India: retrospective analysis of a distinct clinicohematological entity from a tertiary care center and review of literature

Karthik Bommannan,Man Updesh Singh Sachdeva,Pankaj Malhotra,Narender Kumar,Prashant Sharma,Shano Naseem,Jasmina Ahluwalia,Reena Das,Neelam Varma,Gaurav Prakash,Alka Khadwal,Radhika Srinivasan,Subhash 대한혈액학회 2016 Blood Research Vol.51 No.1

BackgroundPlasma cell leukemia (PCL) is a rare and aggressive plasma cell neoplasm. In PCL, clonal plasma cells comprise ≥20% of the peripheral blood (PB) leukocytes and/or the absolute clonal PB plasma cell count is ≥2×109/L. Primary PCL (PPCL) originates de novo, whereas, secondary PCL (SPCL) evolves from pre-existing multiple myeloma.MethodsClinicohematological features, immunophenotypic profile, and survival of PCL patients were analyzed retrospectively.ResultsBetween January 2007 and December 2014, ten PPCL and four SPCL patients were inves-tigated (8 PPCLs and 3 SPCLs had complete clinical data). All were North Indians, sharing common geography and ethnicity. Our cohort showed less frequent renal failure, more frequent hepatomegaly, and non-secretory type disease. In contrast to western literature, flow cytometric immunophenotyping of our cohort revealed altered expression of CD138 (67%), CD56 (33%), and CD20 (0%). With novel therapeutic agents, these PPCL patients had a median overall survival of 15 months.ConclusionWe highlight that our PPCL patients from North India had distinct clinicohematological and immunophenotypic profiles. The significance of our findings must be tested in a larger patient cohort and must be supported by molecular and cytogenetic investigations to un-mask possible significant effects on pathogenesis.