비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

장력구동방식의 역감제시 시스템

신석두,강원찬,오금곤,김영동 조선대학교 에너지.자원신기술연구소 2000 에너지·자원신기술연구소 논문지 Vol.22 No.2

In this paper, we have developed a new Force-Display system using tendon-driven method. The proposed system is based on the HIR Lab Haptic library, which calculates the real position and renders the reflecting force data to device rapidly. The system is composed of device based tendon-driving method, high-speed controller and Haptic rendering library. The developed system will be used on constructing the dynamical virtual environment. To show the efficiency of our system, we designed simulation program which can display the moving force (attaching, grabbing, rotating) on two virtual point. As the result of the experiment, our proposed system shows much higher resolution than any others.

Toxoplasma 감염 가토의 임파구 아세포화 반응에 대한 연구

오창진,이영하,나영언,신대환 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

This study was performed to observe the differences of lymphocyte blastogienic responses in rabbits infected with Fukaya and Me49 strain of Toxoplasma gondii. Rabbits were subcutaneously inoculated with mouse brain emulsion containing 50 cysts of each strain of Toxoplasma gondii. A total of 9 male rabbits was used. From the 1st week after inoculation, blastogenic responses of peripheral blood lymphocytes treated with concanavalin A (Con. A, 10.0㎍/ml), lipopolysaccharide(LPS, 25.0㎍/ml) and Toxoplasma lysate(20.0㎍/ml) respectively were examined by [methyl-^3H]-thymidine incorporation assay at l week interval for 8 weeks. The results obtained in this study were as follows: 1. The blastogenic responses of the Con. A-treated and Toxoplasma lysate-treated lymphocytes from rabbits infected with Fukaya and Me49 strain of Toxoplasma gondii respectively were significantly declined as compared with those of the contol rabbits(p<0.05). No significantly differences were revealed in the blastogenic responses of the experimental group each other. 2. The blastogenic responses of the LPS-treated lymphocytes from rabbits infected with Fukaya and Me49 strain of Toxoplasma gondii respectively were not significantly declined as compared with those of the contol mice. No significantly differences were revealed in the blastogenic responses of the experimental group each other. The results suggested that there were no significantly differences in the blastogenic responses to Con. A, LPS and Toxoplasma lysate of each strain of Toxoplasma gondii infected rabbits. But the experimental group was a significant depression in blastogenic responses to Con. A and Toxoplasma lysate as compared with those of control group.

만화 과제를 이용한 정신분열병 환자의 사회인지 능력의 측정

오정은,나명현,하태현,신용욱,노규식,홍순범,이경진,신민섭,이영호,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : This study is to investigate the hypothesis that schizophrenic patients have difficulty in inferring mental state of others. Methods : Twenty schizophrenic patients and twenty normal subjects were administered to the Cartoon Task required inferring the character's intention in a given context. Results : The schizophrenic patients showed a statistically significant impairment in the Cartoon Task. Both groups chose the card depicting a frequent everyday action significantly more rather than the similar card to the last picture in each story for wrong answers. Conclusion : These preliminary results suggest that schizophrenia is associated with a specific deficit of the cognitive ability referred to as social cognition, and this deficit can be detected not only in the acute phase as found in previous research studies, but also in remission. Also when subjects fail to appreciate what is going on in the minds of other people, they seem to rely on a socially familiar experience.

바이러스 감염 후 발생한 소아에서의 시선경염 1례

신지원,김영대,김우경,박용원,오인경 인제대학교 2009 仁濟醫學 Vol.30 No.-

Optic neuritis presents differently in children than in adults. Children typically have bilateral involvement with papillitis following an antecedent viral illness. The development of multiple sclerosis is less common in children. The diagnosis of optic neuritis is usually made on a clinical manifestations. The major symptoms of optic neuritis include one or more of the following: 1) sudden blurred, "foggy" vision and sudden loss of vision, 2) pain with eye movement in the affected eye, 3) sudden color blindness, and etc. This condition progresses over a few days to two weeks. A 12-year-old girl presented with a history of sudden visual loss and color blindness. Treatment with high doses of steroid resulted in visual function returning to normal.

기계업 종업원의 직무만족·불만족에 관한 연구 : 대전·충남지역을 중심으로 A Case of Tae-Jeon and Chung-Nam Area

오광록,신승종,황영익 大田産業大學校 1997 論文集 Vol.5 No.-

This paper is focused on identifying job-satisfaction level that employee of mechanical industry being located in Tae-Jeon city and Chung-Cheung Provine of Korea. The "two Factor Theory of Motivation" by Herzberg was adapted for this paper. To identify the factors of job-satisfaction, correlation and ANOVA Method was applicated. Following items are the result of researching. 1. To mechanical industry employees motivators are related to job-satisfaction and instead of hygiene factors, motivators are also effected on job-dissatisfaction. 2. The higher education personnel shows the high level of job-satisfation. 3. Finally, the upper position personnel. In conclusion, supervisor or managerial personnel need to recognized and praise subordinate personnel, and give them a fait chancd of promotion.

웹서비스를 위한 음성인식시스템 구현

오신영,김윤중 한밭대학교 정보통신전문대학원 2003 정보통신전문대학원 논문집 Vol.1 No.1

본 논문에서는 웹서비스 기술을 이용하여 음성인식시스템을 구현하였다. 웹서비스를 위한 음성인식시스템은 음성신호분석, 코드북생성, 그리고 VQ인식의 세 과정으로 구성되며 웹서비스로 구동된다. 음성신호분석은 음성데이터를 분석하여 음성의 특징을 추출하는 과정으로 LPC모델을 이용하여 켑스트럴계수를 출력한다 코드북 생성은 인식할 음에 대한 코드북을 생성하는 과정으로 K-mean 알고리즘을 이용한다. 이 코드북은 훈련데이터로부터 인식할 음에 대한 특징을 추출하여 코드워드로 구성한다. VQ인식은 입력받은 음을 인식하는 과정이다. 이 인식방법은 웹사이트를 운영하는 웹서버로부터 받은 음성데이터와 미리 생성된 코드북들의 코드워드와 거리를 비교하여 최소거리를 갖는 코드북의 인덱스 값을 출력하는 방법이다. 이 시스템은 어떠한 웹서버에서 플랫폼에 상관없이 웹서비스를 이용하여 호출함으로써 사용가능하다. 본 논문에서는 웹서비스 기술을 이용한 음성인식시스템을 구현하기 위해 웹 프로그램이 가능한 .NET프래임워크의 C#과 ASP.NET을 이용하였으며, 이 시스템의 성능 분석을 위하여 남자 5명, 여자 5명의 단일 숫자음 음성을 30개씩 채취하여 실험하였다. 그 실험 결과 약 80%의 인식률을 확인하였다. This thesis implemented the speech recognition system for the web service which consists of the speech analysis, the code book generation and the VQ recognition process and the web service function which is able to be called from any web server. The speech analysis process analyzes the speech data and extracts the speech features of the cepstral coefficients of LPC model. The codebook generation process generates the code words from the training data for each speech sound using the modified K-means algorithm The VQ(vector quantization) recognition process is a system that finds out the index of codeword in the codebook which has the minimum distance from the speech data. This system is able to be called from any web server using web service in any platform This system is implemented in the Microsoft .net using the language c# and ASP .net and is tested from the 30 sets of speech data which are uttered 3 times from 5 females and 5 males and gains 80 percents of recognition rates.

六味知黃湯 投與가 高壓環境에 露出된 흰쥐의 血液造成과 臟器造織에 미치는 影響

오재근,강명신,조준용,이영일,최용어 韓國體育大學校附屬 體育科學硏究所 1996 韓國體育大學校附屬 體育科學硏究所論文集 Vol.15 No.1

This study was purposed to investigate the effect of yukmijihwangtang on rat blood components and organ histopathologic changes in the different environments of hyperbaric ambient air. The pharmacological effects of yukmijiwhangtang in oriental medicine have been reported to improve general condition and treat mental and physical weakness due to overload. 84 Male Sparague-Dawely rats, 200-250 g weight, were housed two per cage, fed Standard Rodent Diet with water ad libitum. The animals were assigned to 3 main groups for the blood components and gas analysis : normobaric control group (NC ; N=4), hyperbaric control group (HC ; N=8), hyperbaric medication group (HM ; N=8). HC and HM group were devided into 2 subgroups and kept on different situation of the hyperbaric ambient air (2ATA or 3ATA) for 2 hrs. HM group was administered 10cc extract of boiled yukmijiwhangtang before exposure. For histopathological analysis, hyperbaric groups(HC and HM : N=80) was further devided into 2 subgroups according to atmosphere absolute and exposure period : 2ATA (acute, 1, 2, 3, 4 wks), 3ATA (acute, 1, 2, 3, 4 wks). There were 20 groups in total, with 4 animals in each group. Experimental rats of HM group were administered 10cc extract of boiled yukmijiwhangtang 2 times per day and kept on situation of the hyperbaric ambient air (2ATA and 3ATA) 2 hrs per day for four weeks. In order to record the possible effects of yukmijiwhangtang in hyperbaric condition on the blood components, the rats were killed by decapitation directly after the hyperbaric exposure for 2 hrs. But the administered rats were killed on the morning following the last hyperbaric exposure during 4 wks. The samples were taken 2 hrs, 1, 2, 3, 4 wks after the begining of this study. Blood was collected from posterior abdominal vena cava immediately after decapitation. Organs for histopathological assays in hyperbaric groups (HC and HM) were also removed 2 hrs, 1, 2, 3, 4 wks and fixed at 10% formalin solution. The whole blood of 1㎖ was used for the analysis of pH, PO₂, PCO₂, HCO₃, BE, O₂CT, O₂SAT level by Blood Gas Autoanalyzer (Coning 175, U.S.A). And The rest whole blood of 1㎖ was utilized for the measurement of WBC (white blood cell), RBC (red blood cell), Hb (hemoglobin), Hct (hematocrit), MCV (mean corpuscular volume), MCH (mean corpuscular hemoglobin) level by Microcell Counter (Model; CC-170-TDA Co., Japan). Hematological and blood gas analysis and organ histopathological changes after exposure to hyperbaric ambient air were as follow; (1) Hematological parameters were lower in the hyperbaric medication group than all the control groups without WBC, MCV (2ATA) and MCV, MCH (3ATA). But a statistical significance among the groups was not shown. (2) The hyperbaric medication group was lower than another control groups on all parameters of blood gas analysis after 2 hours exposure to hyperbaric ambient air (2ATA and 3ATA) without O₂SAT. But a statistical significance among the groups was not shown. (3) On observing the histopathological system of the lung with microscope, the congestion, edema and hemorrhage on the alveolar sacs and alveolar wall damage in the hyperbaric control group were heavier than in the hyperbaric medication group.

병원단위의 임상진료지침 개발과정

신영수,김창엽,오병희,한규섭,윤병우,한준구,강영호 한국의료QA학회 1997 한국의료질향상학회지 Vol.4 No.1

Background : With increased concerns about variation among physician a practice pattern and their impact on the quality of care, clinical practice guidelines have been developed by many different organizations, with differing aims and incentives. From the same point of view, there is growing interest in the development of clinical practice guidelines in Korea, but with only a few examples. As a result, there is not much exploration on the incentive and barrier to development guidelines as well as description on the development process. The purposes of this study are to describe the process of the four different clinical practice guidelines in a hospital setting, and to identify incentives and barriers in the development of guidelines. Methods : For this research, a clinical practice guideline development committee and four clinical practice guideline development teams were organized in a university hospital which has more than 1,200 beds. Twenty eight doctors, three nurses, and one technician participated as members of development teams for eight months. Four to six meetings were held, and three to seven departments in the hospital were involved. Results : The topics which developed into clinical practice guidelines were cardiopulmonary resuscitation(CPR), blood transfusion, anticoagulation, and angiography. The main goals set by teams were education(CPR, angiography), risk management(blood transfusion), and to enhance quality of care(anticoagulation). Among four teams, only in the team for anticoagulation guideline medical record review and pilot-testing were performed. Also literature review was not carried out systematically. However, all the guidelines were developed by multidisciplinary participation by personnels of related departments. All the team expected guidelines to be used as standard protocols in the practice. Conclusion : Experience and skill in developing process has to be improved to have a more valid and useful practice guideline. In particular, literature review and problem identification by examining medical record should be emphasized. Also further studies of the clinical outcomes of the guidelines application and changes in physicians behaviors would be required.

지속성 외래 복막투석 환자의 복막염

신영태,황평주,김종학,강민규,구영선,양종오,장윤경,이강욱 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

CAPD has established itself as an effective method maintaining the patients with end stage renal disease. CAPD peritonitis is one of the most important complication of peritoneal dialysis. We analyzed the incidence, pathogens, and outcome of the peritonitis, of the 95 patients who underwent CAPD at CNUH from January 1993 to July 1998. The result were as follows : 1) A total of 72 episodes of peritonitis occurred during this periods. The incidence of peritonitis were 0.64/patient/year. 2) The first episode of peritonitis was occurred within a year in 75%, within two year in 95.8%. 3) The rate of positive and negative culture were 27.8% and 72.2% respectively. Gram positive organisms were cultured in 60%, Gram negative organisms in 40%. S. aureus were most prevalent organisms(30%). 4) The cure rate were 83.3% in Gram positive organisms and 62.5% in negative organisms. 5) Peritoneal catheter were removed in 18 cases. Among them, 7 cases are due to peritonitis. In conclusion, improved technology and increasing patients' effort to careful management of catheter will reduce the incidence of peritonitis.