한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

Floristic characteristics of vascular plants and first distributional report of Pseudostellaria baekdusanensis M. Kim in Yongneup wetland protected area

Young-Chul Kim,Hyun-Hee Chae,Sang-Heock Oh,Seung-Ho Choi2,Moon-Pyo Hong3,Gi-Heum Nam,Jae-Yoon Choi,Hyun-Sook Choi,Kyu-Song Lee 한국환경생태학회 2015 한국환경생태학회지 Vol.29 No.2

Yongneup wetland protected area, the only high moor in Korea, is a core area to conserve biodiversity. Even though the Yongneup wetland protected area is relatively small, various plant species are distributed in the Yongneup wetland protected area because it includes various habitats showing different environmental gradients. Vascular plants distributed in the Yongneup wetland protected area were identified as a total of 376 taxa that is composed of 73 families, 217 genera, 322 species, 3 subspecies, 44 varieties and 7 forms. For endangered plants designated by the Ministry of Environment, 5 species including Trientalis europaea var. arctica, Lilium dauricum, Halenia corniculata, Lychnis wilfordii and Menyanthes trifoliata were found and 34 taxa were confirmed to be distributed only in the mountainous wetland habitats. Regarding naturalized plants, a total of 11 taxa were distributed, but most of them were distributed in the areas where artificial interference has occurred. And in areas inside the wetlands that are relatively well preserved, 2 species of Bidens frondosa and Erigeron annuus were observed. In this study, the occurrence and distribution of Pseudostellaria baekdusanensis M. Kim, which was recently found in Mt. Baekdu and reported as a new species, were identified in the Yongneup wetland protected area. A wetland is a very vulnerable area to drastic environmental changes and damages to its ecosystem could cause the extinction of rare plant species which are distributed only in the wetlands. Therefore, it is mandatory that current status of the Yongneup wetland protected area is evaluated and actions to prevent rapid environmental changes are taken. Fourteen separate investigations were conducted in 2013 and another four in 2014, to evaluate current status of the Yongneup wetland protected area. These investigations have provided us the basic information for future actions of conservation and restoration.

대학생형 설립에 관한 연구

최승빈,이규금,이정호 목원대학교 사회과학연구소 1998 社會科學硏究 Vol.- No.2

응급의료센터에서 신경색의 조기진단

최경호,오동렬,이원재,박규남,박승현,황두영,김형국,정시경,김영민,김세경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

To evaluate appropriate diagnostic studies for renal infartion in emergency medical center, we analysed 33 patients of renal infarction treated in this hospital for last 8 years. Eleven patients, 4 trauma associated and 7 aortic disease associated patients were excluded. They are 11 males and 11 females with a mean age of 51 years. Fourteen came to the emergency medical center and seven came to the outpatient department, in the other one patient renal infarction was developed during hospitalization with other disease. On their past history they had hypertension in 9, valvular heart disease in 5, and diabetic mellitus in 4 patients. Abdominal or flank pain was noted in 17 of 22(77%). The other symptoms were vomiting, nausea, fever and so on. On microscopic examination of initial urine in hospital, 5 patients showed more than 10 red blood cells by high power field examination. The mean lactic dehydrogenase level was 1,239 I.U/L(normal range 218-472 I.U/L), while the mean aspartate aminotransferase and mean alanine aminotransferase were 51 I.U/L(normal range 13-36 I.U/L) and 44 I.U/L(normal range 5-33 I.U/L). Abdominal ultrasonography showed positive findings in 5 of 16(31%), of which 3 were confirmed by Doppler ultrasonography. In 18, computed tomography was done and all those showed positive findings of renal infarction(100%). In conclusion, it is important that identify the elevated lactic dehdrogenase level in case of any suspicion about renal infarction and confirm by computed tomography.

韓國産·中國産 운지(Coriolus versicolor(Fr.) Quel)의 抗腫瘍 成分에 관한 比較 연구

崔乘基,金泰均,林雄圭 서울대학교 농과대학 농업개발연구소 1993 서울대농학연구지 Vol.18 No.1

韓國産과 中國産 雲芝 Coriolus versicolor (Fr.) Quel의 抗腫瘍成分의 수율과 종양억제율을 비교하기 위해, 단백결합다당류를 유기용매침전과 ultrafiltration method에 의해 分離, 定量하였다. 한국산 Coriolus versicolor (Fr.) Quel의 항종양 성분의 수율은 13.8%였고, 중국산 Coriolus versicolor (Fr.) Quel의 항종양 성분의 수율은 12.7%였다. 한국산과 중국산 시료간에 종양억제율에는 유의성 있는 차이가 보이지 않았다. To Compare the yield and inhibition of ratio antitumor constituents of Coriolus versicolor (Fr.) Quel in Korea and China, protein-bound polysaccharides were isolated and quantitated by organic solvent precipitation method and ultrafiltration method. The yield of antitumor constituents of C. versicolor (Fr.) Quel in Korea was 13.8% and the yield of antitumor constituents of C. versicolor (Fr.) Quel in China was 12.7%. The inhibition ratio of both did not showed significant value..

AHP 기법에 의한 금융위험관리 소프트웨어 평가에 관한 연구

최희성,황규승 한국경영과학회 1999 經營 科學 Vol.16 No.2

Recently, financial institutions in Korea are experiencing an unfamiliar challenge in terms of their operational risk management due to the volatility of global financial market and the incessant development of new financial products in this paper, we present an AHP(Analytic Hierarchy Process) model to evaluate the effectiveness of commercial softwares for risk management in banking The AHP model considers software's performance, utility, serviceability and durability as major evaluation criteria The weight of each criterion is generated by the questionnaire survey given to practitioners in risk management in domestic commercial banks

프레탈^(R)정(실로스타졸 50mg)에 대한 실로졸^(R)정의 생물학적 동등성

최한곤,권기철,이승호,김학미,박병주,유봉규,이종달,이경희,하정희,우종수,박인숙,최진석,용철순 한국병원약사회 2003 병원약사회지 Vol.20 No.1

Bioequivalence of two cilostazol tablets, the Pletaal^(R)(Korea Otsuka Pharmaceutical Co., Ltd.) and the Cilozol^(R)(Hanmi Pharmaceutical Co., Ltd.), was evaluated according to the guideline of KFDA, Sixteen normal male volunteers(age 20~29 years old) were divided into two groups and a randomized 22 cross-over study was employed. After two tablets containing 50㎎ of cilostazol were orally administered. blood was taken at predetermined time intervals and the concentration of cilostazol in plasma was determined with an HPLC method using UV detector. The pharmacokinetic parameters(C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters. The results showed that the differences in C_(max), T_(max) and AUC_(t) between two tablets were 4.99%, 1.74% and 7.68%, respectively. The powers(1-β) for C_(max), T_(max) and AUC_(t) were83.92%, 80.12% and 85.03%, respectively. Detectable differences(Δ) and confidence intervals were all less than 20%, and confidence interval of all the parameters were also less than 20% at the significance level(α) of 0.05. All of these parameters met the criteria of KFDA for bioequivalence, indicating that Cilozol^(R) tablet is bioequivalent to Pletaal^(R) tablet.

자궁경부질도말에서 Atypical Glandular Cells of Undetermined Significance (AGUS)로 나타난 자궁경부의 표재성 자궁내막증 - 2예 보고 -

최혜정,이승구,김규래 대한병리학회 2001 Journal of Pathology and Translational Medicine Vol.35 No.3

흰쥐에서 심정지후 뇌의 허혈-재관류 손상과 Tumor Necrosis Factor-α의 상관관계

최승필,박규남,박승현,박상현,정시경,김세경 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

Background : Tumor necrosis factor-α(TNF-α) has been thought to play a major role in neurological injury during global brain ischemia and subsequent reperfusion following resuscitation in cardiac arrest. So, we hypothesized that the elevation in TNF-α was dependent upon the duration of the global brain ischemia, and related to delayed neuronal damage. Methods : Fourteen rats were divided two groups ; 1 minute-cardiac arrest group(n=7) and 3 minute-cardiac arrest group(n=7). we induced cardiac arrest by chest compression and clamping of tracheal tube for 1 minute and 3 minutes respectively. And then, resuscitation was initiated. To measure the plasma activity of TNF-α, blood samples were drawn before and at the end of cardiac arrest, and 30, 60, 90, and 120 minutes after initiation reperfusion. At 72 hours after resuscitation, the ND(neurologic deficit) score was determined and the histopathologic outcome of hippocampal CA1 neuron was observed by the percent dead hippocampal CA1 neurons. Results : 1. TNF-α level during the early reperfusion period(<2h) was significantly increased in 3 min-cardiac arrest group compared with 1 min-cardiac arrest group(p=0.0001). 2. There was a no significant difference of neurologic deficit score between 1 min-and 3 min-cardiac arrest. 3. Percent dead hippocampal neurons were significantly increased in 3 min-cardiac arrest group compared with 1 min-cardiac arrest group(9.1±1.2% vs 1.2±0.9%, p<0.05). Conclusions : The results suggest that longer duration of global brain ischemia causes a more profound increase in plasma TNF-α level during the early reperfusion period(<2h) and more delayed neuronal damage than lessor duration of global brain ischemia, and that increase in TNF-α level during the early reperfusion period(<2h) is related to delayed neuronal damage.

動力耕耘機用 디젤 機關의 騷音特性

崔圭洪,李承奇,安義成 건국대학교 산업기술연구원 1994 건국기술연구논문지 Vol.19 No.-

국내에서 생산보급되고 있는 動力耕耘機用 8PS 디젤기관의 騷音 狀態를 파악하고자 消音器 전방 1m 위치 및 운전자 위치에서의 모터 구동시와 연소 구동시 각 회전수별 騷音을 측정 비교 분석하고 기관에서 발생하는 소음중 에너지 비율이 가장 높은 排氣音을 제어하기 위해 소음기를 부착시와 소음기 제거시 및 空洞의 體積을 변화시킨 경우의 각 回轉數別 騷音度, 燃料消費率, 出力 등을 측정 분석하여 현 소형 디젤기관의 騷音 減少方案 모색의 기초자료로 제시하고자 실시한 시험의 결과는 다음과 같다. 1) 機關의 回轉數가 증가함에 따라 騷音은 높아지는 것으로 나타났으며, 기존 機關의 경우 機械騷音은 85dB 이상으로 이의 騷音低減對策이 필요하다고 생각된다. 2) 消音器 附着時와 除去時 무부하 운전시와 전부하 운전시 騷音은 소음기 부착시가 제거시에 비해 각각 4, 13.1dB 정도 낮게 나타나 비교적 소음감쇄 효과가 높았다. 3) 空洞體積 變化에 따른 消音器別 騷音은 기존의 소음기 T-Ⅰ 보다 空洞의 체적을 증가시킨 T-Ⅱ, T-Ⅲ가 운전자 위치 및 소음기 전방 1m 위치에서 無負荷 運轉時 각각 1.9∼2.3dB 및 2∼2.8dB, 全負荷 運轉時 각각 4.9∼5dB, 7.1∼7.5dB 감소한 것으로 나타났다. 4) 각 회전수별 燃料消費率은 T-Ⅰ, T-Ⅱ, T-Ⅲ가 거의 같은 경향을 나타냈으나, 소음기를 제거한 경우는 약 17g/PS·hr 정도 낮게 나타났다. 또, 출력은 소음기를 부착한 경우가 제거한 경우에 비해 각각 0.55PS 낮게 나타났다. 5) 排氣騷音을 최대한으로 감소시키기 위하여 금후 機關出力 감소가 적고, 騷音 減少效果가 높은 形態의 消音器 開發硏究가 이루어져야 할 것으로 생각된다. This study was conducted to evaluate the noise characteristic of 8PS agricultural diesel engine through the modification, was found to provide the foundamental data that could be used to reduce the noise of the engine. To evaluate the noise characteristics on the agricultural diesel engine by the muffler, noise level, specific fuel consumption and output were measured in case of the with and without muffler and three different volume of muffler cavity. The results of the study are summarized as follows: The noise increased by the increament of revolution velocity. The mechanical noise of power tiller indicated more than 85dB at 1,800∼2,200rpm. Therefore, to minimized bearing ability of operator, it was thought that the countermeasure of noise reduction need. The noise level with the muffler was smaller than those without muffler by 4dB, 13.1dB. respectively. In case of increased the volume of muffler cavity, the noise level at the position of working seat was decreased 1.9∼2.3dB at the time of no-load condition and 4.9∼5dB at the time of full load, respectively. The specific fuel consumption of the without muffler type was 17g/PS hr lower than the with muffler type. The output of the without muffler type was 0.55PS higher than the with muffler type, respectively. To reduce of the exhaust noise, it is necessary to continue researches on the relationship between complex factors of the noise.