한국 주요정신장애의 유병률 및 관련요인 : 2006 전국정신질환역학조사

조맹제,장성만,함봉진,정인원,배안,이영문,안준호,원승희,손정우,홍진표,배재남,이동우,조성진,박종익,이준영,김진영,전홍진,이해우 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives The aims of this study are to estimate the prevalence of the DSM-IV psychiatric disorders in the Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI), and to compare those with previous studies. Methods The Korean Epidemiologic Catchment Area study Replication (KECA-R) was Conducted between August 2006 and April 2007. The sampling of the subjects was carried out across 12 catchment areas. A multistage, cluster sampling design was adopted. The target Population included all eligible residents aged 181o 64 years. Face-to-face interviews were conducted with the Korean version of Composite International Diagnostic Interview (K-CIDI) based on the DSM-IV (N=6,510, response rate=81.7%). Results A total of 6,510 participants completed the interview. The lifetime and 12-month prevalence rates for all types of DSM-IV disorders were 30.0% and 17.3%, respectively. Those of Specific disorders were as follows : 1) alcohol use disorder, 16.2% and 5.6% ; 2) nicotine use disorder, 9.0% and 6.0% ; 3) specific phobia, 3.8% and 3.4% ; 4) major depressive disorder, 5.6% and 2.5% ; and 5) generalized anxiety disorder, 1.6% and 0.8%. Data relating to nicotine and alcohol use disorder revealed a very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among females than males. Conclusion The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in the distribution of psychiatric disorders across the country and times were observed.

四季統 바이라스에 對한 結球배추의 反應

李昇雨,金炅濟 동국대학교 농림과학연구소 1967 農林科學 論文集 Vol.1 No.-

1. The thirteen different solid-headed type chinese cabbage varieties thatwas produced by three seed's companies is examined into severity of symptoms that inoculated into Streak Mosaic Virus, Radish Vivrus P. Turnip Mosaic Virus T8 and Radish Mosaic Complex. 2. The Uri 50days variety is relatively resistant to Streak Mosaic Virus. 3. The Uri Horticultural No. 1 is relatively resistant to Radish Virus P. 4. The Uri 50 days Variety is relatively resistant to Turnip mosaic Virus T8. 5. The Uri 50 days Variety is relatively resistant to Radich Mosaic Virus Complex. 6. Jungang Owng Kowan is relatively resistant into fields.

다형성교아세포종을 동반한 Von Recklinghausen氏 병 1예

이현개,이종수,백민우,이승재,박효일,지제근 인제대학교 1981 仁濟醫學 Vol.2 No.4

가족성으로 신경섬유종증에 동반되는 중추신경계의 종양으로 수막종, 신경교종, 신경초종 등이 있으며 이들은 드물지 않게 보고되었다. 그러나 신경교세포에 생기는 종양 중 신경섬유종증에 동반되어 대뇌에 생긴 다형성교아세포종은 매우 드물다. 본 교실에서 가족성으로 발생한 신경섬유종증의 환자에 동반된 다형성교아세포종을 경험하였으며 가족중 부친은 von Recklinghausen씨 병을, 또 두 자녀는 다발성 cafe´ au lait spots를 가지고 있었다. The tumors of the central nervous system associated with familial neurofibromatosis are meningioma, glioma, and neurilemmoma, which are not uncommon. Of the glial tumors of the central nervous system, the association of cerebral glioblastoma multiforme with neurofibro matosis is very rare. We have experienced the unusual coincidence of neurofibromatosis and glioblastoma multiforme in a 33 year old man, whose father was afflicted with von Recklinghausen's disease and whose son and daughter had also multiple cafe´ au lait spots on their bodies.

외상성 뇌 손상 환자에서 노동 능력 상실률과 신경 인지 기능 및 사회적, 직업적 기능과의 관계

이제선,노승호,남청강 대한생물치료정신의학회 2002 생물치료정신의학 Vol.8 No.1

고교 야구 선수들의 견관절 외회전 및 내회전근의 근력 및 그 특성

이제운,윤승호 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

The imbalance of rotator muscles of shoulder frequently causes shoulder injury in many baseball players. This study was intended to evaluate the strength characteristics of external and internal rotator muscles in high school baseball players. Isokinetic tests of external/internal rotators were performed using Cybex Ⅱ^+ Isokinetic dynamometer in nine pitchers, thirteen nonpitchers and twenty normal control subjects. And the flexibility of external rotator muscles of shoulder was evaluated by the hand-to-shoulder-blade Test. The results were as follows : 1) In pitchers, mean peak torque ratios of external/internal rotators were significantly high in nondominant side at 180 and 300 deg/sec, mean peak torque and mean peak torque body weight ratios of external rotators were significantly high in nondominant side at 180 deg/sec, 180 and 300 deg/sec respectively, mean peak torque of internal rotators were significantly high in dominant side at 300 deg/sec. 2) In nonpitchers, peak torque ratios of external/internal rotators were significantly high in nondo minant side at 180 deg/sec, but peak torque and peak torque body weight ratios of internal rotators were both significantly high in dominant side at 180 and 300 deg/sec. 3) In comparison between pitchers and nonpitchers, peak torque ratios of external/internal rotators in dominant side were significantly high in nonpitchers at 180 and 300 deg/sec, but there were no significant differences in nondominant side. 4) In flexibility tests of external rotators, pitchers showed statistically significant tightness in external rotators than nonpitchers and control group in dominant side, but there were no statistically significant differences in nondominant side. In conclusion, pitchers showed weakness and tightness in shoulder external rotators, which may lead to major shoulder injury. Therefore evaluation of muscle power and flexibility was thought to be one of the very useful screening tests for the prevention of shoulder injury.

Treacher Collins 증후군 환아의 증례보고

박지현,김승혜,송제선,김성오,이제호 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.3

Treacher Collins 증후군(TCS)은 25,000명에서 50,000명당 1명의 빈도로 비교적 드물게 발생하는 난치성 질환이다. 이 질환은 정상적인 부모에게서 돌연변이로 발생하거나 상염색체 우성으로 유전된다고 알려져 있다. 하악과 상악, 협골의 발육 부전, 부정교합, 양측성 이개 기형, 안검렬의 반몽고증 사면(antimongoloid slant)이 특징적이며, 종종 구순열, 구개열, 외이도 폐쇄, 중이와 내이의 기형에 의한 청각소실, 왜소증, 심장과 골격의 이상 등을 동반한다. 또한, 인두의 형성부전, 소구, 거설증, 악골의 기형에 기인하여 수면 중 무호흡증, 만성 폐쇄성 무호흡증 등의 호흡 장애가 있을 수 있으며, 전신마취 유도 시에 기관내 삽관이 어렵다고 보고된 바 있다. 치과의사는 관련 신드롬에 대한 충분한 이해를 통해 환자에게 보다 안전하게 치료를 제공해야 하며 구강 건강 관리 및 선천성 안면 기형에 대한 문제 해결을 돕기 위해 적절한 치료 및 안면 수술에 관련된 가이드를 제시해야 한다. 본 증례는 전반적인 치아우식을 주소로 연세대학교 치과병원 소아치과에 내원하여 외래에서 치아우식 치료를 받은 TCS 환아에 대한 것으로, 문헌 고찰을 통해 얻은 다소의 지견을 함께 보고하는 바이다. Treacher Collins syndrome(TCS) is a rare, incurable condition occurring in approximately 1 of 25,000 to 50,000 births. It may occur as a spontaneous mutation out of genetically normal parents or it may be manifested as an autosomal dominant pattern. TCS is characterized by facial deformities such as, underdevelopment of the maxilla, mandible and zygoma, malocclusion, bilateral deformities of auricles, antimongoloid slant of the palpebral fissures. The syndrome is often associated with cleft lip and palate, ear malformations and hearing loss, short stature, and anomalies of the heart and skeleton. Respiratory difficulty associated with air way obstruction may also be observed, and there is considerable difficulty in airway management during general anesthesia. It is necessary that dentists provide safe dental treatments and guidelines to TCS patients by providing adequate understanding about the characteristics of the syndrome and proper ways of managements. The purpose of this study is to report the dental and medical characteristics of the patient who visited the Department of Pediatric Dentistry, Yonsei University for multiple dental caries treatment and to review the literatures of TCS.

비동기식 적응형 파이프라인 구조 설계

이승숙,이제훈,조경록 충북대학교 컴퓨터정보통신 연구소 2006 컴퓨터정보통신연구 Vol.14 No.2

본 논문은 비동기식 프로세서에서 동작 상황에 따라 파이프라인 구조가 변경 가능하고 명령어 종류에 따라 병렬처리를 지원하는 적응형 파이프라인 구조를 제안하였다. 제안된 구조는 스테이지 스키핑(stage-skipping)과 스테이지 통합(stage-combining) 기법을 지원한다. 이 기법들은 명령어 종류에 따라 서로 다른 데이터패스를 사용하는 명령어들을 병렬로 처리하여 머신 사이클을 단축시켜 프로세서의 동작 속도를 증가시킨다. 본 논문에서는 제안된 파이프라인 구조를 적용한 ARM 명령어 호환 프로세서를 설계하였다. SPEC2000 벤치마크를 사용하여 성능을 평가한 결과, 타겟 프로세서는 평균 365 MIPS의 속도로 동작하여 영국 맨체스터 대학에서 개발한 비동기 프로세서인 AMULET3i에 비해 2.3배 높은 성능을 보였다. This paper presented an adaptive pipeline architecture for a high-performance and low-power asynchronous processor. The proposed pipeline architecture employs a stage-skipping and a stage-combining scheme. By using these schemes, the proposed pipeline architecture can reduce the processing time and power consumption. Also, the proposed architecture supports multi-processing in the EX stage that executes parallel 4 instructions. We designed an asynchronous ARM processor to prove the efficiency of the proposed pipeline architecture. We used SPEC2000 benchmark programs for evaluating the performance of the target processor. As a result, the proposed architecture showed about 2.3 times higher speed than the asynchronous counterpart, AMULET3i.

한국판 스미스클라인 비챰의 '삶의 질'척도를 이용한 공황장애 환자의 삶의 질에 관한 연구

이승호,제영묘,김상엽,이대수,최은영 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.1

Objectives : In this study, we researched the change of 'quality of life(QOL)' of patient with panic disorder by KvSBQOL and the predictors affecting the change of 'quality of life'. Methods : 30 outpatient with panic disorder were tested by questionnare for panic disorder and KvSBQOL. Frst, they were classified as when healthy before panic episodes(a point of time 1), when first diagnosed as panic disorder in the psychiatry(a point of time 2), and when treated after diagnosis(a point of time 3). Second, the change of QOL scores in five factors at each point was observed, Third, the correlation between the change of QOL scores(point 3 score-point 2 score) and the several predictors(Onset age, Degree of change in panic symtom, Degree of change in anticipatory anxiety, Degree of change in agraphobia, Spended time to diagnose panic disorder, Duration of treatment) were studied. Results : 1) QOL mean scores of a point of time 1,2 and 3 were 166.267±38.24, 94.367±34.00, 161.367±34.37, respectively. 2) The change of QOL scores in all five factors of KvSBQOL(factor1 Competence, factor2 Psychological well-being, factor3 Stability, factor4 Physical well-being, factor5 Activity)at each point was significant(P<.000). 3) The change of QOL mean scores(point 3 score-point 2 score) have significantly negative correlation with the change of score in anticipatory anxiety but not other predictors. Conclusions : Difference in QOL scores between a point of time 1 and 3 is 4.9, indicating that the psychiatric treatment is important in improvement of QOL, the anticipatory anxiety is an important predictor of QOL(P<.001). and it suggested that diminished anticipatory anxiety is very important to maintain of high QOL in patient with panic disorder.

미세가공기술을 이용한 Interdigitated Array 전극의 제작 및 응용

이강신,김태한,김승렬,신민철,이원용,박제균 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

Interdigitated array (IDA) electrodes were fabricated using silicon technology for highly sensitive biosensing. Thin-film platinum and gold IDA electrodes were fabricated with 10 μm band width and 7 μm gap between the bands using photolithographic techniques. The IDA electrode has 100 fingers consisting of 50 finger anodes and 50 finger cathodes. By applying both the oxidation and the reduction potentials of a reversible redox couple, ferrocyanide, to the pairs of the IDA electrode, an increased current generation can be observed. In our experiment, the collection efficiency of IDA electrode was 46% and amplification factor was 12.6. This preliminary experiment implies that the IDA electrode could be applied to biosensor fabrications as the sensitive electrochemical transducer when a lower detection limit is needed such as phenol sensor for drinking water analysis.

착화제와 유기산이 Wistar rat체내의 Sr 분포에 미치는 영향

이기호,이제호,박상윤,이승훈,유용운,윤택구 대한방사선 방어학회 1990 방사선방어학회지 Vol.15 No.2

Wistar rat에 85SrCl2를 꼬리 정맥에 주사하여 체내 기관과 혈액 내 분포, 잔존율을 조사하였고 착화제와 유기산을 투여하여 혈장 단백질에 결합하는 Sr양의 변화를 측정하였다. 혈액내에서 Sr은 혈장에 60%, 세포에 40%부착되어 이동하였다. 혈장에 존재하는 Sr중 약 50%정도는 혈장 단백질과 결합한 상태였고, 세표에는 세포 표면에 가볍게 부착되어 있었다. Erythrocyte나 granulocyte보다 lymphocyte에 많은 양의 Sr이 부착되어 있었다. 투여후 초기 1시간 이내에 혈액 내에서 급격히 감소하여 뼈에 침착되었다. 이때 각 기관에서도 Sr의 잔존율은 24시간 이내에 크게 감소하였고, 뼈로 침착된 Sr은 24시간 이후에 서서히 감소하였다. 착화제 EDTA, EGTA 및 DTPA를 투여한 경우, 혈장 단백질에 결합하는 Sr의 양은 대조군의 57%에서 27-33%로 감소하였으며 citrate 및 oxalate의 투여시는 이값이 19%와 40%로 각각 감소하였다. 85SrCl2 was injected to the tail vein of Wistar rats and investigated its distribution and clearance in the tissues and blood. We also measured the changes in Sr binding to the blood plasma protein by administrating chelating agents and organic acids. For the blood, 60% of the Sr occurred in the plasma and 40% on the cell membrane. Fifty percent of Sr in the blood plasma was bound to plasma protein. Sr on the cell membrane seemed to be bound loosely. The binding in the lymphocyte was higher than in the erythrocyte and granulocyte. Within one hour Sr was quickly disappeared from the blood stream, to be accumulated in the bone. Twenty four hours after the injection, Sr decreased rapidly in the organs of soft tissue, but slowly in the bone. The binding of Sr to plasma protien decreased from 57% of the control to 27-33% in the group treated with chelating agents. EDTA. EGTA and DTPA and to 19% and 40% in the groups treated with organic acids, citrate and oxalate, respectively.