정신분열병, 기분장애와 보르나 바이러스

정성훈,원승희,김상헌 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.2

Borna disease virus is a unique neurotropic agent that appears to have a predilection for the limbic area of the brain. In some animal species, it can produce a behavioral syndrome characterized by aggressive and passive phases. These two characteristics has suggested the relationship between schizophrenia, mood disorder and Borna disease virus. Borna disease virus can infect human brain tissue possibly contributing to the pathophysiology of specific human neuropsychiatric disorders. The authors reviewed several articles suggesting an association of Borna disease virus with schizophrenia and mood disorder.

황소개구리(Rana catesbeiana) 위장관 점막의 점액분비세포에 대한 조직화학적 연구

정승돈,이정훈 경남대학교 기초과학연구소 2001 硏究論文集 Vol.15 No.-

본 연구는 황소개구리(Rana catesbeiana) 위장관 점막의 점액물질의 성상을 알아보기 위하여 위장관(위, 십이지장, 소장, 대장)의 조직들을 통상조직 절편법에 의해 제작한 조직을 hematoxylin & eosin, periodic acid-schiff(PAS), alcian blue pH 2.5(AB 2.5), alcian blue pH 1.0(AB 1.0), AB 2.5-PAS 연속 염색 반응을 실시한 결과는 다음과 같았다. 1.위에서 표면점액세포와 점액경세포는 주로 풍부한 중성점액질로 구성되어 있었고, 미량의sulfomucin도 나타났다. 2. 십이지장에서 원주세포는 거의 중성점액질로 이루어져 있었는데, 중등도 반응의 주름쪽이 약한 반응의 소와쪽 보다 중성점액질을 더 많이 포함하고 있었다. 배상세포는 드물게 나타났고 크기도 작았으며, 소량의 sulfomucin과 풍부한 중성점액질을 포함하고 있었다. 3. 소장의 원주세포는 십이지장의 원주세포와 동일한 결과를 나타내었다. 배상세포의 수는 적었고, 점막상피에 흩어져 있었으며, 중등도의 sulfomucin과 풍부한 중성점액질을 포함하고 있었다. 4. 위장관 중에서 점액질의 분비가 가장 왕성한 대장에서 원주세포는 중등도의 중성점액질로 구성되어 있었고, 배상세포는 중성점액질과 중등도의 sulfomucin을 내포한 산성점액질 모두 아주 풍부하게 포함되어 있었다. This study was performed to examine the composition of gastrointestinal mucosa mucosubstances in bullfrog (Rana catebeiana). The stomach, duodenum, small intestine and large Intestine of adult bullfrogs were made the general routine section method Specimen were stained with hematoxylin-eosin, periodic acid-Schiff(PAS), alcian blue pH 2.5 (AB 2.5) and alcian blue pH 1.0 (AB 1.0) respectively. AB 2.5-PAS sequential staining reactions differentiated acidic mucin from neutral mucin. The results of the study were as follows. 1) Surface mucous cells and mucous neck cells of stomach were mainly composed of very abundant neutral mucin, and also they showed a very small amount of sulfomucin. 2) Columnar cells of duodenum mainly consisted of neutral mucin. Folds of moderate reaction secreted more neutral mucin than crypts of weak reaction. Goblet cells which contained a small amount of sulfomucin and abundant neutral mucin. 3) Columnar cells of small intestine showed the same results as those of duodenum. Other goblet cert Is contained a moderate amount of sulfomucin and plenty of neutral mucin. 4) Columnar cell of large intestine which secreted mucin flour ishingly among gastrointestinal tracts were made up of a moderate quantity of neutral mucin. Other goblet cells produced neutral mucin very abundantly, and a very large amount of acidic mucin which contained a proper amount of sulfomucin.

제주도 연안 갈치, Trichiurus lepturus 채낚기 어구의 생력화 : 3. 집어등의 수중조도

오승훈,서익조,김병엽,이창헌,정용진,서두옥,김동근 제주대학교 해양연구소 2001 해양자원연구소연구보고 Vol.25 No.-

國內 물푸레나무(Fraxinus rhynchophylla)와 광릉물푸레(F. densata)의 分類學的 實體

朱勝勳,張珍成,全正壹,張桂羨,李興洙 서울大學校農業生命科學大學附屬樹木園 2003 서울大學校 樹木園 硏究報告 Vol.- No.23

물푸레나무속(Fraxinus L.)에서 소엽의 길이와 너비, 동아의 털의 밀도는 속내 종 구분에 있어 주요한 형질이다. 국내에 분포하는 물푸레나무(F. rhynchophylla)와 일본의 F. japonica, 한국의 광릉물푸레(F. densata)와 일본의 F. longucuspis 간의 분류학적인 관계는 혼란이 있어왔다. 본 연구에서는 소엽의 길이와 너비, 동아의 털의 유무를 측정하기 위하여 119개의 물푸레나무와 광릉물푸레나무 표본을 이용하였다. 형질 분석 결과 물푸레나무와 광릉물푸레는 정소엽의 길이와 폭의 비율에서 차이를 보였으나, 동아의 털의 밀도와 모양, 소엽의 개수와 같은 다른 형질에서는 차이를 보이지 않았다. 그러나 한국에서 북쪽에서 남쪽으로 갈수록 소엽의 폭이 좋아지는 경향을 보이고 있다. 또한 광릉의 개체들이 타 지역의 개체들보다 동아의 길이가 길지만, 정소엽의 폭은 남쪽에서 북쪽으로 향할수록 좁아지는 양상을 띠었다. 동아의 길이는 광릉 지단이 타 집단에 비해 긴 동아를 갖는 것으로 나타났다. 정소엽의 형태와 정소엽 및 동아의 털 밀도를 비교한 결과 상호 상관관계가 존재하지 않았다. 기존에 영양 형질을 기준으로 물푸레나무와 별개의 종으로 인식되었던 광릉물푸레는 물푸레나무의 변이체인 것으로 판단되며, 일본의 F. japonica와 F. longicuspis, 한국의 물푸레나무와 광릉물푸레 역시 형태적인 차이에 있어서 변이에 대한 충분한 인식이 없었던 것으로 여겨지지만, 이에 대한 더 많은 연구가 수행되어야 한다. The characters of leaflet length, width, and hair density of winter bud are important to recognize many taxa of Fraxinus. The systematic relationships between F. rhynchophylla in Korea and F. japonica in Japan, and F. densata in Korea and F. longucuspis in Japan were confused and were not clarified yet. One hundred nineteen specimens of F. rhychophylla and F. densata were used to evaluate the correlation between the length and width of leaflet, and absence/presence of trichome in bud. From this study, the morphological discontinuity between F. rhynchophylla and F. densata was partially present only in the ratio of length and width of terminal leaflet, but other characters, such as hair density on winter bud, bud shape, and the number of leaflet, were not useful for delimitation. However, the ratio of length and width of terminal leaflet appeared to show clinal variation with changes from north to south in Korea. In general, there Although the length of winter bud was longer in Gwangneung than those in other area, there was no correlation between the morphology of terminal leaflet and hair density of terminal leaflet and winter bud. The previous species, F. densata in Korea were indistinguishable from the typical form of F. rhynchophylla on the basis on vegetative characters, rejecting continued recognition of this taxon as a distinctive species. The morphological differentiation between F. japonica and F. oongicuspis in Japan and F. rhynchophylla and F. densta in Korea was not considered sufficient to warrant recognition of either specific or varietal status, but should be further examined.

스포츠에 의한 경수손상(頸髓損傷)에 관한 분석

이승훈,이신언,임정일 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.2

This study have focuses on 21 cases of spine-neck broken at S hospital in seoul. Breaking spine-bone neck have occurred frequently at young ages. There are 6 cases of smashed fracture, 8 cases of both-side joint dislocation, 2 cases of one-side joint dislocation. And there are eight cases of entire broken, three cases of intermediate broken, 1 case of brown-sequard, three cases of middle part broken, 6 cases of knot broken. There are 0 or 2 cases occurred annually, and it doesn't mean sudden decreasing of fractures. Most of cases are able to prevent, but the wounds didn't take any preventive actions. If preventive curing methods are make, it will decrease effectively. We must make several preventive plans to reduce fatal spine-neck fracture.

철근 이음형 PC 보-기둥 내부 접합부의 구조적 거동에 관한 실험적 연구

김승훈,하상수,문정호,이리형,이강철,전병갑 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

In this study, new moment-resisting precast concrete beam-column joint is proposed for moderate seismic regions. It has the connection reinforcing bars, penetrated the joint and lap-spliced with the bottom bars of precast U-beam. An experimental study was carried out to investigate the joint behavior subjected to reverse cyclic loading and constant axial compressive load. Three precast beam-column interior were tested. The variables examined were the type of connection reinforcing bars and presence of transverse reinforcement in joint. Joint performance is evaluated on the basis of connection .strength, stiffness, energy dissipation, and drift capacity. Based on the test results, the precast connection is capable of matching or exceeding the performance of the monolithic connection and thereby provides the sufficient moment-resisting behavior to be applicable for moderate seismic regions.

충청지방에서 발생한 한국형 출혈열 104예의 임상적 고찰

이정호,신승훈,김민범,신영태 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

A clinical study was carried out on 104 cases of Korean Hemorrhagic Fever who were admitted to Chungnam National University Hospital from Januray 1982 to December 1988. 104 cases among the patients were confirmed -by serologic test. The resutls were as follows: 1. The peak monthly incidence was November. The peak age incidence were 5th and 6th decade and male to female ratio was 2.5:1. The occupation of the patients were variable, but farmer was the most prevalent. 2. Most patients entered hospital in oliguric stage and the mean duration from onset of symptoms to admission was 5 days. 11 OUT OF 104 patients were non-oliguric stages. 3. The reguent and pertinent symptoms and signs were fever, chills, general myalgia, abdomical patin, back pain, abdominal and costovertebral angle tendernes sand bleeding tendencies. 4. The important laboratory findings for diagnosis were leukocytosis, thrombocytoenia, elevated blood urea nitorgen and creatinin. 5. Hypertension was noticed transiently in 42 cases(40.4%). Other complications were infection, melena, pleural effusion, convulsion and premature repture of membrane in pregnancy in 4, 3, 3, 2 and 1 cases respectively. 6. 26 patients who showed severe acute renal failure were treated with acute hemodialysis while 78 patients with conservative treatment. All patients except one who developed unidentified cerebral dysfunction were discharged with improvement.

TFELD 절연층을 위해 ITO glass위에 증착된 (Ba_(0.5),Sr_(0.5))TiO₃박막의 특성

김정환,배승춘,권성렬,정훈,박진우,김기완 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

We have studied that dielectric and electrical properties of (Ba_(0.5),Sr_(0.5))TiO_(3) thin films deposited on Indium Tin Oxide-coated glass substrate by using rf-magnetron sputtering method in this paper. Substrates were heated at room, 300℃ , 400℃, and 500℃. Working pressure was changed 5mTorr, 10mTorr, 20mTorr, 30mTorr respectively substrates temperature, and Ar:O_(2), ratio was fixed 9:1. SEM analysis was conducted to investigate thickness of BST thin films. Dielectric constant, current-voltage(I-V), and transmittance were measured. We observed difference of that thickness, dielectric constant, current-voltage(I-V), and transmittance due to variable substrates temperature and working pressure. We also obtained best conditions at 400℃, 30mTorr. Dielectric constant was 209.1 at 1kHz, leakage current density was below 7.35X10^(-7)A/cm^(2) at 100V, and transmittance was over 91%.

우울과 관련된 장애를 가진 환자들의 PAI 프로파일

두정훈,강종구,노승호,오상우 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

한국어판 정신분열병 삶의 질 척도의 개발과 PANSS와의 관련성

김진훈,임선진,민성길,김승업,손소정,Diane J Wild,박성혁,이황빈 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5

Objectives : The present study was performed to verify the validity and value of 4th revision of Schizophrenia Quality of Life Scale (SQLS-R4) as an assessment tool in a Korean-language version (SQLS-R4K). Methods : The subjects for present study were 174 patients with a diagnosis of schizophrenia as defined by DSM-IV. The SQLS-R4K was administered together with self-report Korean version of World Health Organization Quality of Life-Brief Scale(WHOQOL-BREF) to assess validity. A subset of respondents also completed the SQLS-R4K for a second time to assess test-retest reliability. To evaluate the relationship SQLS-R4K and clinical characteristics, psychotic symptoms and general functioning were evaluated using the Positive and Negative Syndrome Scale (PANSS) and the Global Assessment of Functioning Scale (GAF) score respectively. Results : All the scales of SQLS-R4K showed good internal consistency reliability. The correlations of items with their scale total revealed that all items were significantly correlated with their own scale score. In test-retest reliability, paired t-tests indicated that responses did not alter significantly between the two assessment. There was moderate correlation between WHOQOL-BREF sub-scores and SQLS-R4K score total. Also relevant correlations between PANSS, current GAF and SQLS-R4K were proved. Conclusion : From the results of the testing the reliability and validity of the SQLS-R4K, it is concluded that the SQLS-R4K is a simple and reliable scale for measuring quality of life in schizophrenic patients.