이하선 종양에 관한 임상적 연구

백승,오희균,박홍주,유선열,김원재 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.3

This is a clinical study on 113 patients, who were treated for parotid tumors at Chonnam National University Hospital over a period of 5 years from January 1996 to December 2000. The results were as follow, 1. The mean ages were 42.6 years old (12~73 years) for benign parotid tumor patients and 43.9 years old (2~74 years) for malignant patients. 2. The ratio of male to female was 1:2 in malignant parotid tumors, but there was no difference in sex distribution of benign tumor. 3. There was no difference in mean mass size and duration of illness between benign and nalignant tumor patients. 4. The combined use of fine needle aspiration biopsy and computed tomograph was common as the diagnostic method of parotid tumor 5. The parotid tumors were commonly located in the superficial lobe(69%). 6. The ratio of benign and malignant tumors was 4:1. The most common benign tumor was pleomorphic adenoma (72% of benign tumor), followed by Warthin's tumor and monomorphic adenoma. The most common malignant tumor was rnucoeplderrnoid carcinoma(45% of malignant tumor). followed by adenoid cystic carnoma. carcinoma ex pleomorphic adenoma, and adenocarcinoma. 7. The most common operations were superficial parotidectomy (72%) for benign parotid tumor and total parotidectomy (45%) for malignant tumor 8. The most common postoperative complication was temporary facial nerve weakness (82%), followed by Frey's syndrome (14%) and permanent facial palsy (4%). 9. Postoperative radiation therapy was done in 12 patients and the mean radiation dose was 5550±620cGy. 10. Of 113 cases. tumor recurrence developed in 12 cases (10%). These results suggest that the successful management of parotid gland tumors needs adequate surgical treatment on the basis of knowledge of parotid gland anatomy and preoperative diagnosis.

Mo¨ssbauer 분광법을 이용한 10MnO_2-10Fe_2O_3-30Na_2O-50SiO_2 유리내의 Fe^3+ 이온에 관한 연구

洪致裕,朴冠鎬,白承道,洪性樂 동국대학교 1986 論文集 Vol.25 No.-

We have studied the Mo¨ssbauer parameters for Fe^(3+) ion in the quenched glass and heat treated glass and heat treated glasses. The Mo¨ssbauer spectra of the quenched glass were investigated at various temperatures from 60K to 300K. Using the center shift and kinetic temperature, the Debye and einstein temperatures were calculated. The quenched glass was heat-treated at various temperatures from 530℃ to 710℃ for five hours. Both the isomer shit and quadrupole splitting parameters decreased near 590℃. And regardless of heat treatment, the Fe^(3+) ion was predominantly octahedrally coordinated.

혼합유화제 비율에 따른 인계난연제 캡슐의 제조 및 특성 연구

백경현,이준영,홍상현,김중현 한국공업화학회 2004 응용화학 Vol.8 No.1

The microcapsules containing triphenyl phosphate (TPP) flame retardant have been prepared by using the epoxy resin (Novolac Type) with good physical properties and network structure. The reactants including TPP, epoxy resin and mixed surfactants were emulsified to oil in water (O/W) by the phase inversion technology and then conducted on the crosslinking of epoxy resin by In-situ polymerization. The capsule size and size distribution of TPP microcapsules was controlled by mixed surfactant ratio. The thermal property of TPP capsules were measured by the TGA. The morphology and capsule size were also investigated by the SEM respectively. TPP capsules with 1 : 1 of mixed surfactant (F127 : SDBS) ratio were more spherical and uniform than it with others. The TPP capsule size was 12~17㎛ and TGA results shows that TPP capsule efficiency was about 73%.

정상인 직장도찰 피검물에서의 혐기균의 분리빈도

백상홍,이상원,진동찬 全北大學校 學徒護國團 1981 全國大學生學術硏究發表論文集 Vol.6 No.-

This study was made to isolate anaerobic bacteria from the rectal swabs of normal healthy persons and determine the normal flora of the intestine. Rectal swab specimens were obtaianed from normal healthy adults in Seoul. As the processes of bacteriological study, anaerobic bacteria were cultured in thioglycollate semisolid broth and isolated on brain heart infusion blood supplement agar plates, and biological properties were examined including the hemolysis on blood agar plated, gas production in the fluid media. Biochemical test was performed by Minitek Anaerobic Set (BBL^*) in anaerobic Gas Pak Jar (BBL^*) The result is as followings: 1. Among the 110 rectal swab specimens, 187 strains of anaerobic bacteria were isolated. The isolates included 88 straing (47.1%) of Gram positive bacilli, 74 strains (39.5%) of Gram negative bacilli and 25 strains (13.3%) of Gram positive cocci. 2. After preservation at-80 C in thioglycollate broth, only 134 strains (71.1%) of isolates survived. Theses survivors included 76 strains of Gram positive bacilli (survival rate 86.4%), 38 strains of Gram negative bacilli (survival rate 51.4%), and 20 strains of Gram positive cocci (survival rate 80.8%). 3. From these strains, 50 strains were randomly selected by the ratio of morphologic groups of isolates for the sugar fermentation and other biochemical tests. Among these selectes and tested straing, the determined were : Eubacterium aeroficiens 27 strains(54.0%) Bacteroiaes melaninogenicus 7 strains (14.0%) Peptostreptococcus produtus 6 strains (12.0%) Eubacterium limosum 1 strains (2.0%) and the undetermined strains were : Gram negative bacilli 7 strains (14.0%) Gram positive bacilli 1 strain (2.0%) Gram negative cocci 1 strain (2.0%)

Ni1-xCdxFeAlO₄계의 Mossbauer 스펙트럼 연구

홍성락,고정대,백승도 濟州大學校 基礎科學硏究所 1998 基礎科學硏究 Vol.11 No.2

Ni1-xCdxFeAlO₄계의 Mossbauer스펙트럼은 x가 0.2이하인 경우에는 초상자성 이완현상을, x가 0.3~0.5인 경우에는 준강자성에 의한 sextet를 x가 0.7, 0.8인 경우에는 강자성 이완현상, x가 0.8이상인 경우에는 상자성에 의한 doublet가 나타난다. x가 0.2이하인 시료에서 치환된 Cd²이온은 주로 A-site의 Al³이온을 B-site로 이동시키고, 계속적인 Cd²이온의 증가에 따라 A-site의 Fe³+ 이온도 B-site로 이동하게 된다. Ni1-xCdxFeAlO₄계의 초상자성 이완 현상은 A-site의 Al³이온에 의한 것으로 강자성 이완현상은 치환된 Cd²+이온에 의한 것으로 설명할 수 있고, Yafet-Kittel자기구조에 따라 Ni1-xCdxFeAlO₄계의 자기적 성질을 해석할 수 있다. The Mossbauer spectra of the Ni1-xCdxFeAlO₄system were investigated with the Cd content X at room temperature. The spectra of the samples exhibit various patterns as follows 1) superparmagnetic relaxation for 0≤x≤0.2, 2)ferrimagnetic sextet for 0.3≤x≤0.5, 3) ferromagnetic relaxation for x=0.6, 0.7, 4)paramagnetic doublet for 0.8≤x≤1, with the Cd content x. In the samples with X values from O to 0.2, the substituted Cd²+ ions transfer the Al³+ ions from A-site to B-site mainly. The superparamagnetic relaxation effect and the ferromagnetic relaxation effect are derived from the Al³,Cd²respectively. The magnetic structrue of the Ni1-xCdxFeAlO₄system was explained by the Yafet-Kittel model.

무기수은을 투여한 흰쥐에서의 신장독성에 대한 착화제 효과 및 병리조직학적 변화

고상백,홍순원,차봉석 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2

This study was to determine the effects of Sodium-N-[4-methoxybenzyl]-D-glucamine-N-dithiocarbamate (MeOBGDTC) on the nephrotoxicity of mercury and histopathological change in rats pretreated with mercuric chloride 48h earlier. In a first experiment, 3 groups were given a single injection i.p. of 3.5㎛ol/Kg of Hgcl₂ mixed with 1μCi of 203Hg²+ in a final volume of 0.5ml of physiologic saline. Subsequently the rats also received the chelator, 1mmol/Kg of MeOBGDTC, at 1h in group 2 (Hgcl₂-MeOBGDTC 1h) and 12h in group 3 (Hgcl₂-MeOBGDTC 12h) after injection of mercuric chloride. The results showed that the injection of chelating agent at 1h after mercury injection significantly decreased mercury level in plasma. But not significant in renal cortex. In a second experiment, rats were divided into 4 groups, one group was control group, others were mercury injected group. MeOBGDTC was also administered to mercury-injected, rats as described above. The changes in renal function were determined by measurement of proteinuria, plasma creatinine and urinary osmolality. The results showed that the injection of mercuric chroride incrased the excretion of urinary protein and plasma creatinine, and decreased the urinary osmolarity. However, the injection of chelating agent at 1h after mercury injection significantly decreased the toxic effects of mercury. Finally, histopathological change at the light microscopic level was comparable effect of chelating agent on nephrotoxicity of mercury. Minimal morphological alterations were seen in kindly of rats of Hgcl₂-MeOBGDTC 1h. The Hgcl₂-MeOBGDTC 12h caused necrotic change of the proximal tubule at cortical-medually junction. These changes were more common and more severe at the Hgcl₂alone.

일부 조선업 근로자의 직업성 요통 발생실태 및 위험요인에 관한 연구

고상백,김형식,최홍렬,김지희,송인혁,박준한,박종구,장세진,차봉석 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목적 : 이 연구에서는 한 사업장의 동일한 코호트내에서 직업성 요통의 발생 및 발생원인에 대해 조사하고자 하였다. 방법 : 연구대상은 1995년 12월 현재 한 조선업체에 종사하는 근로자 중에서 1995년 12월 31일 까지 요통이 이미 발생한 근로자와 1995년 당시 검진 미수검자를 제외한 9,784명을 연구대상으로 하였다. 요통 발생군은 1996년부터 1998년까지 3년간 추적 관찰하여 요통으로 4일 이상 통원 또는 입원치료를 받은 근로자로 하였다. 발생률은 요통발생 당시 연도를 기준으로 하여 해당 연도의 4일 이상 신규치료를 받은 중등도 이상의 요통근로자를 분자로 하였고, 해당년도 사업장의 종사하는 근로자 총수(과거 요통자 제외)를 분모로 간주하였다. 요통 발생군은 외상성 요통과 직업관련성 요통으로 대별하였으며, 위험요인과 질병 발생간의 관련성을 보기 위한 Cox모형에서 그 위험도를 파악하고자 할 때에는 직업성 요통만을 환자군으로 선정하였다. 결과 및 결론 . 요통 발생률은 근로자 천명당 1998년 3.1명, 1997년 8.8명, 1996년 7.8명이었다. 요통점유율의 범위는 10.99∼25.66이었다. 연령별 요통 발생률은 30대, 40대에서 높은 발생률을 보였다. 진단명에 따른 발생률은 추간판 탈출증, 염좌, 척추골절, 척추분리증, 척추협착증 순이었다 직업성 요통 발생자들의 직업적 요인을 알아보기 위하여 요통 발생 당시 작업형태를 알아본 결과, 물건을 들다가 66명(35.3%)이 발생하여 가장 큰 빈도를 차지하였고, 물건을 옮기는 과정에서 19명(10.2%)이 발생하여 2위를 차지하였고, 넘어지거나(8.6%), 물건을 당기는 자세(8.0%), 값자기 일어서다(7.5%) 순으로 요통이 발생하였다. 직업성 요통에 영향을 주는 일반적 특성 및 직업적 특성에 판한 상대위험도 및 95% 신뢰구간를 구한 결과, 요통발생에 영향을 주는 유의한 변수로는 체질량 지수(비만도), 교대여부, 중량물 취급여부였다. Objectives : This study was conducted to estimate the incidence rate, and to identify the risk factors for the occupational low back pain among shipyard workers. Methods : The study subjects consisted of 9,784 workers who were employed in a ship-building industry (excluded workers who had a history of low pack pain before 1995 or did not take periodic health examination in 1995) . The cases were 220 people who experienced back pain from January 1, 1996 to December 31, 1998. To assess risk factors for occupational low back pain, Cox propotional hazard model was used. Results : During the recent three years from 1996 to 1998, the incidence rate per 1,000 persons was 7.8 in 1996, 8.8 in 1997, and 3.1 in 1998. The main causes of work-related low back pawn were sprain, strain and disc herniation. Lifting was the most common cause of back pain (35.3%) , and carrying (10.2%) and pulling (8.0%) were followed. In Cox proportional harzard model, independent risk factors for back pain were body mass index(R.R. ; 1.54, 95% C.1. : 1.06-2.25), shift work(R.R. ; 1.65, 95% C.1. : 1.19-2.28), and lifting heavy material(R. R., 3.95, 95% C.1. : 2.29-6.82). Conclusions . This study suggests that the risk factors of back pawn In shipyard work-ers were body mass index, shift work and lifting.

하청 근로자들의 건강수준 평가

최홍열,고상백,장세진,차봉석,임형준,이상윤,김재용,강동묵,조수헌 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.1

목 적 : 하청노동을 이용한 노동 유연화 전략은 근로자들의 고용을 불안정시키고, 근로자들의 삶에 부정적 영향을 미치고 있다. 따라서 이 연구는 하청업체 근로자들의 고용현황을 조사하고, 기존의 업체중심의 건강평가의 문제점을 지적하고자 하였다. 또한 하청업체 근로자들의 건강평가의 현재적 의미와 사회적 배제의 특성을 알아보고자 하였다. 방 법 : 모기업과 하청업체 근로자들의 건강수준을 비교하기 위하여, 정기건강진단(일반, 특수)과 채용건강진단 자료를 이용하고자 하였다. 건강진단에서 누락된 비정규직을 포괄하기 위하여 SF-36을 이용하여 건강설문조사를 시행하였다.결 과 : 조선업 하청업체 근로자들의 고용기간은 짧고, 빈번한 노동이동 현상을 보였다. 3년간 건강진단 수검 현황을 통해 살펴볼 때, 1998년 수검자중 2000년까지 연속해서 검진 받은 수검자는 40.3%였다. 건강진단 결과 유소견자 규모를 통해 모기업과 하청업체간의 건강수준을 비교해 보았다. 모기업은 일반질병 요관찰자와 질병자를 포함한 유소견자가 1,011명으로 약 10 %의 유소견율을 보이고 있고, 질병자의 경우 596명으로 유병률이 5 %를 상회하고 있다. 반면 하청업체의 경우 1,967명의 수검자중 유소견자가 115명으로 6 %의 유소견율을 보이고있고, 질병자는 82명으로 4 %의 유병률을 보이고있다 채용건강진단을 받은 수검자는 6,260명 이었으며, 이 중 유소견자 수는 2,373명으로 전체 수검자의 37.9 %를 차지하였다. 건강설문지의 경우는 전체 건강수준의 총합은 하청보다 원청 근로자가 높았고 통계적으로 유의하였다. 결 론' 정기건강검진 결과는 하청근로자들이 고용형태에 따라 검진을 받지 못한 경우가 많아, 건강 근로자 효과로 표현될 가능성이 있다. 따라서 채용건강진단 결과는 다른 측면에서 하청업체 근로자들의 건강수준의 현실적 반영이라고 할 수 있다. 향후 하청업체 근로자들의 건강문제를 감시하고 개선하려면 기존의 업체 중심의 접근으로는 하청 근로자의 건강문제를 제대로 다룰 수 없고, 업종과 지역을 동시에 고려하여 접근할 필요가 있다. 또한 단기 고용 근로자 및 비정규직 근로자를 사회보장의 확충과 모기업의 연대책임 강화 및 기업복지 차원에서 포괄하는 방안이 모색되어야 하겠다. Objectives : The strategy for the labor flexibility through subcontracted labor have brought a negative effect on the lives of the workers, such as the increase of the unstable employment. This study was conducted to analyze the relationship between the employment of subcontracted firms and the health status of them, and to find out some problems which have been caused in the process of health evaluation and the characteristics of social exclusion. Methods : We reviewed the periodical health examination and preemployment health examination in order to compare health status of the subcontracted workers with those of the parent firm workers. The SF-36 questionnaire was administered to assess the self-perceived health status. Results : The result shows that compared to the working duration of the parent firm workers, those of the subcontracted workers were shorter, and the job transfer rate was higher. In the periodical health examination, the prevalence of occupational and general disease was higher in the parent firm(10%) than in the subcontracted firms(6%). Preemployment health examination plays an important role in worker's health manage- ment. Among 6,260 workers who received preemployment health examination, the prevalence of disease was 37.9%. Mean scores of health status measured by SF-36 were lower in the subcontracted firm than in the parent firm. Conclusions : Due to social exclusion of the subcontracted workers from the periodical health examination, there is a possibility that the periodical health examination have the healthy worker effect. These results suggests that the preemployment health examination could be a more appropriate indicator which is able to assess the health status of the subcontracted workers than the periodical health examination.

조선업 도장작업자의 유사노출군과 노출변이; 크실렌 노출을 중심으로

고상백,노영만,임현우,신용철,김수근,최홍열,김재용,장성훈 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

목적 : 조선업 도장 작업자의 크실렌 노출을 평가하기 위하여, 수행직무 및 밀폐특성에 따라 유사노출군으로 구분하여 노출 변이 및 동질성을 파악하고자 하였다. 방법 : 3회 이상 반복측정이 이루어진 근로자 중동일공정에서 직무상 변동이 없는 근로자 총 28명을 대상으로 하였다. 노출농도 값을 대수전환(lOgtransformation)하여 근로자간, 근로자내 노출 분산요소을 추정하기 위하여, nested randomeffects ANOVA model을 활용하였다. 선정된 유사노출군 내 구성원의 측정 평균이 동일하다고 할수 있는지를 검정하기 위하여 분산요인(9f)을 산출하였고, 쿨즈0.031일 경우 동일하다고 생각하였다.또한 노출 값을 대수전환하여 95 %의 근로자(b-R9s)가 2배수 범위 내에 측정값을 가질 경우 동일하다고 생각하였다. bwRSS의 값을 유사노출군내의 근로자들간(between worker)의 기하표준편차(bwsy)를 구한 후 exp(3.92 bwsy)로 계산하여 산출하였고, 그 값이 2이하이면 동일하다고 생각하였다. 결과 : 일반적으로 유사노출군은 노출농도가 비슷한 것이라는 생각과는 달리, 직무에 근거한 유사노출군은 동질성 검정상 이질적이었다. 분무도장과 붓도장 모두 bwRss은 2를 초과하였고, 룰 또한 0.031를 초과하여 변이 폭이 컸다. 그러나 밀폐특성에 따른 노출 분포의 변이성은 직무만으로 구분했을 때의 변이지표 보다 그 수치가 낮아 밀폐특성으로 직무의 변이성을 설명 할 수 있었다. 결론 : 직무에 근거한 유사노출군이 동질적이지알다는 결과는 유사노출군으로 구분된 근로자의 업무특성이 하나의 유사노출군으로 설정할 수 없다는 점을 시사한다. 따라서 향후 작업환경 측정 시 직무뿐만 아니라 특정 업무(specific task) 또는 세부작업현황까지 파악할 필요성을 제시하고 있다. Objectives : This study was conducted to assess the concentration of xylene exposure and exposure variability of a similar exposure group (SEG) in accordance with job title and confined space. Method : The study subjects included 28 workers working in the painting process in the ship-building industry. Measurement of subjects were repeated three times. Within and between-worker exposure valiance components were estimated from log-transformed exposure concentrations employing a one-way nested random effects analysis of variance model. A uniformly exposed group was defined as one where the between-worker variance(σB2) was less than or equal to 0.031 or bwR95 ≤2, where bwR95 =exp(3.92 bwSy) , representing the radio of the mean exposures of the 97.5th and 2.5th percentile groups of the workers sampled. Result : The results indicated that, contrary to popular belief, similar exposed groups based on job title were heterogeneous. The between-worker variance(σB2) is large(≥0.031) and the ratios of the 97.5th and 2.5th percentile workers of the log normally distributed exposures of each group of worriers was more than 2. However dividing job title into confined space (in-block, out-block, in/out-block) decreased the between-worker exposure variability. Conclusion : This study focused on the quantitative aspects of exposure in painters in the ship-building industry. We cannot accept the assumption that SEG are uniformly exposed, as a major component of variation in exposure relates to differences in tacks or other factors. Therefore, the observational schemes can be improved by investigating Job-specific task and practice.

건설회사의 사전 안전성 평가모델에 관한 연구

손창백,홍성호 한국안전학회 2003 한국안전학회지 Vol.18 No.2

In order to improve the safety performance of construction projects, effective and corporative safety management program between head office and job site must be implemented. And its performance must be measured and analyzed for the identification of the problems in the safety management area. This study proposes a previous evaluation model of safety performance for the large construction firm in order to enhance their safety level. The fundamental data for proposed model is based on the past research(Son 2002), which is structured of evaluation criteria weighted factor. statistical evaluation formula. The model would help the firm management in identifying the weak areas of safety performance in terms of the degree performing certain safety tasks. It is expected that the model could contribute to achieving the "zero accident" level.