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      • KCI등재

        All Sky Camera and Fabry-Perot Interferometer Observations in the Northern Polar Cap

        Qian Wu,Timothy L. Killeen,Stanley C. Solomon,Donald J. McEwen,Weiji Guo 한국해양과학기술원 2002 Ocean and Polar Research Vol.24 No.3

        We report all sky camera and Fabry-Perot interferometer (FPI) observations of mesospheric gravity waves and a 12-hour wave at Resolute (75oN) and a joint observation of 10-hour wave with Eureka (80oN). All sky camera observations showed a low occurrence of mesosphere gravity waves during equinoxes, which is similar to the mid-latitude region. A slightly higher occurrence near solstice appears to indicate that gravity waves are not filtered out by the neutral wind in the winter. The FPI observation of a 12-hour wave showed amplitude variations from day to day. The phase of the wave is mostly stable and consistent with the GSWM prediction in the winter. The phase shifts with season as predicted by the GSWM. Four events of the 12-hour wave were found in spring with amplitudes larger than the GSWM predictions. The FPIs at Resolute and Eureka also observed a wave with period close to 10 hours. The 10-hour wave maybe the result of the non-linear interaction between the semi-diurnal tide and the quasi-two day wave. Further studies are under way. Overall, the combined Resolute and Eureka observation have revealed some new features about the mesospheric gravity wave, tidal wave, and other oscillations.

      • KCI등재

        A new phenanthrene derivative and two diarylheptanoids from the roots of Brassica rapa ssp. campestris inhibit the growth of cancer cell lines and LDL-oxidation

        Qian Wu,백남인,Jin-Gyeong Cho,유기현,정태숙,박지해,Su-Yeon Kim,Ji-Hyun Kang,정인식,최명숙,이경태,Hae-Gon Chung,방면호 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.4

        Brassica rapa ssp. campestris (Brassicaceae) isa conical, deep purple, edible root vegetable commonlyknown as a turnip. We initiated phytochemical and pharmacologicalstudies to search for biological active compoundsfrom the roots of B. rapa ssp. campestris. Weisolated a novel phenanthrene derivative, 6-methoxy-1-[10-methoxy-7-(3-methylbut-2-enyl)phenanthren-3-yl]undecane-2,4-dione, named brassicaphenanthrene A (3) alongwith two known diarylheptanoid compounds, 6-paradol (1)and trans-6-shogaol (2), through the repeated silica gel(SiO2), octadecyl silica gel, and Sephadex LH-20 columnchromatography. The chemical structures of the compoundswere determined by spectroscopic data analyses includingnuclear magnetic resonance, mass spectrometry, ultravioletspectroscopy, and infra-red spectroscopy. All compoundsexhibited high inhibitory activity against the growth ofhuman cancer lines, HCT-116, MCF-7, and HeLa, with IC50values ranging from 15.0 to 35.0 lM and against LDL-oxidationwith IC50 values ranging from 2.9 to 7.1 lM.

      • Incidence and Mortality of Female Breast Cancer in Jiangsu, China

        Wu, Li-Zhu,Han, Ren-Qiang,Zhou, Jin-Yi,Yang, Jie,Dong, Mei-Hua,Qian, Yun,Wu, Ming Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

        Objectives: The aim of this study was to describe and analyze the incidence and mortality of female breast cancer in Jiangsu Province of China. Methods: Incidence and mortality data for female breast cancer and corresponding population statistics from eligible cancer registries in Jiangsu from 2006 to 2010 were collected and analyzed. Crude rates, age-specific rates and age-standardized rates of incidence and mortality were calculated, and annual present changes (APCs) were estimated to describe the time trends. Results: From 2006 to 2010, 11,013 new cases and 3,068 deaths of female breast cancer were identified in selected cancer registry areas of Jiangsu. The annual average crude incidence and age-standardized incidence by world population (ASW) were 25.2/ and 17.9/100,000 respectively. The annual average crude and ASW for mortality rates were 7.03/ and 4.81/100,000. The incidence was higher in urban areas than that in rural areas, and this was consistent in all age groups. No significant difference was observed in mortality between urban and rural areas. Two peaks were observed when looking at age-specific rates, one at 50-59 years and another at over 85 years. During the 5 years, incidence and mortality increased with APCs of 4.47% and 6.89%, respectively. Compared to the national level, Jiangsu is an area with relatively low risk of female breast cancer. Conclusion: Breast cancer has become a main public health problem among Chinese females. More prevention and control activities should be conducted to reduce the burden of this disease, even in relatively low risk areas like Jiangsu.

      • SCOPUSKCI등재

        All Sky Camera and Fabry-Perot Interferometer Observations in the Northern Polar Cap

        Wu Qian,Killeen Timothy L.,Solomon Stanley C.,McEwen Donald J.,Guo, Weiji Korea Institute of Ocean ScienceTechnology 2002 Ocean and Polar Research Vol.24 No.3

        We report all sky camera and Fabry-Perot interferometer (FPI) observations of mesospheric gravity waves and a 12-hour wave at Resolute $(75^{\circ}N)$ and a joint observation of 10-hour wave with Eureka $(80^{\circ}N)$. All sky camera observations showed a low occurrence of mesosphere gravity waves during equinoxes, which is similar to the mid-latitude region. A slightly higher occurrence near solstice appears to indicate that gravity waves are not filtered out by the neutral wind in the winter. The FPI observation of a 12-hour wave showed amplitude variations from day to day. The phase of the wave is mostly stable and consistent with the GSWM prediction in the winter. The phase shifts with season as predicted by the GSWM. Four events of the 12-hour wave were found in spring with amplitudes larger than the GSW predictions. The FPls at Resolute and Eureka also observed a wave with period close to 10 hours. The 10-hour wave maybe the result of the non-linear interaction between the semi-diurnal tide and the quasi-two day wave. Further studies are under way. Overall, the combined Resolute and Eureka observation have revealed some new fractures about the mesospheric gravity wave, tidal wave, and other oscillations.

      • A Study on Development of the Optimal Neural Network in GMA Welding Process

        Wu, Qian Qian,Lee, Ji Hye,Lee, Jong Pyo,Park, Min Ho,Kim, Young Su,Kim, Ill Soo Trans Tech Publications, Ltd. 2014 Advanced materials research Vol.936 No.-

        <P>Gas Metal Arc (GMA) welding is considered as a multi-parameter process that it’s hard to find optimal parameters for good welding. To overcome the problem, an artificial neural network based on the backpropagation algorithm was built to realize the relationships between process parameters and welding quality as output parameter. In this study, Mahalanobis Distance (MD) was employed to evaluate the availability of a given welding parameters which was proved to performance well in multivariate statistics. Input parameters such as welding current and arc voltage were chosen due to their significant influence on the welding quality. To improve the precision of given parameters’ evaluation, neural networks with different configurations were verified. The analyses on the measured and predicted MD by the proposed neural network were conducted. The proposed neural network based on the error backpropogation algorithm was proved to have high reliability to evaluate process parameters, which further makes it available in on-line monitoring system.</P>

      • Hierarchical and symmetric infant image registration by robust longitudinal-example-guided correspondence detection : Hierarchical and symmetric infant image registration

        Wu, Yao,Wu, Guorong,Wang, Li,Munsell, Brent C.,Wang, Qian,Lin, Weili,Feng, Qianjin,Chen, Wufan,Shen, Dinggang Wiley (John WileySons) 2015 Medical physics Vol.42 No.7

        <P>To investigate anatomical differences across individual subjects, or longitudinal changes in early brain development, it is important to perform accurate image registration. However, due to fast brain development and dynamic tissue appearance changes, it is very difficult to align infant brain images acquired from birth to 1-yr-old.</P>

      • 중국 가족기업의 지배구조가 경영성과에 미치는 영향: 상장된 제조업인 가족기업 대상으로

        QIAN WU,남영호 글로벌경영학회 2018 글로벌경영학회 학술대회 발표논문집 Vol.2018 No.1

        본 연구는 가족의 지배구조, 기업의 지배구조와 경영성과 간의 관계를 살펴보는 게 본 논문의 목적이다. 가족기업은 가족과 기업의 근간이므로 일반기업과 다른 가족목표도 갖고 있으며, 가족 기업의 지배구조는 일반기업과의 차이가 될 수도 있다. 본 연구에서 가족기업의 지배구조는 기업의 지배구조와 가족의 지배구조를 나누어 경영성과에 대한 관계를 고찰하였다. 본 연구는 위의 연구목적을 달성하기 위해, 상해·심천증권거래소 사이트와 CSMAR(国泰安) 금융데이터베이스를 통해 중국에서 A주 상장된 가족기업에 관한 데이터를 수집하였다. 우리 잘 알다시피 중국은 제조업 강한 국가이며, 2016년도에 A주 상장된 가족기업 수가 1022개인데 제조업에 속한 가족기업이 700개 넘게 나왔다. 그러므로 본 연구는 A주 상장된 제조업에 속한 가족기업 대상으로 연구하였다. 그 중 ST 기업, PT기업, 자료를 수집하지 못 하는 기업을 제외해서 704개 기업을 최종적으로 정하였다. 그리고 가설을 검증하기 위한 실증분석은 SPSS18.0을 사용하여 실시하였다. 연구결과, 기업의 지배구조인 이사회 규모와 사외이사 수는 기업의 매출액과 당기순이익에 유의한 정(+)의 영향을 끼쳤다. 또한 가족의 지배구조인 경영지배권은 기업의 매출액과 당기순이익에 유의한 정(+)의 영향을 끼쳤지만, 가족의 지배구조인 소유권은 기업의 매출액과 당기순이익에 부 (-)의 영향을 끼쳤다는 것을 검증하였다. 결론적으로, 가족기업에서 이사회와 사외이사의 감시 기능을 잘 수행할 수 있도록 제도나 관리 이년 등 측면에서 많이 발전하게 된다고 보일 수 있다. 또한 가족은 기업에 대한 경영지배권이 높을수록 경영성과를 증가할 수 있었다. 그러나 가족의 소유권이 높아지면 경영성과가 상대적으로 하락한다는 것을 활인할 수 있다. 왜냐하면 오너가 기업의 발전뿐만 아니라 가족목표도 가지고 있다. 그러므로 가족의 발전을 위하여 기업의 단기적인 재무성과를 포기할 가능성도 있기 때문이다.

      • KCI등재

        Soybean GmAOC3 promotes plant resistance to the common cutworm by increasing the expression of genes involved in resistance and volatile substance emission in transgenic tobaccos

        Qian Wu,Hui Wang,Juanjuan Wu,Dagang Wang,Yongli Wang,Lei Zhang,Zhiping Huang,Deyue Yu 한국식물학회 2015 Journal of Plant Biology Vol.58 No.4

        The evaluation and use of endogenous soybean genes is an effective strategy to minimize the yield losses caused by insects. Allene oxide cyclase (AOC) catalyzes the most important step in the biosynthesis of jasmonate (JA), which plays a crucial role in plant defense against insects. In this study, the role of GmAOC3 in plant insect resistance was evaluated. Real-time PCR results indicate that GmAOC3 was uniquely and rapidly activated and attained peak expression in leaves after attack by the common cutworm (CCW). In insect bioassays, transgenic lines overexpressing GmAOC3 were significantly less damaged than wild-type plants, and the relative growth rate of CCW fed with leaves from transgenic lines was significantly lower than that of CCW fed with leaves from wild-type plants. Electron microscopy revealed that the density of leaf trichomes in transgenic lines overexpressing GmAOC3 was greater than that in wild-type tobacco. Several physiological and morphological indicators, including JA, phenolic content and the relative expression levels of the putrescine N-methyltransferase (PMT) and proteinase inhibitor (PI) genes, phenylalanine ammonia lyase (PAL) activity and volatile substances, increased in the transgenic plants overexpressing GmAOC3. Our findings indicate that GmAOC3 plays an important role in soybean resistance to CCW and can be used as a resource for plant breeding.

      • KCI등재

        Stigma and Efficacy of Zhizhu Kuanzhong Capsules Versus Doxepin in the Treatment of Refractory Functional Dyspepsia: A Randomized Controlled Trial

        Qian-Qian Wang,Li Cheng,Bi-Yu Wu,Hong-Yi Qiu,Ping Xu,Bo Wang,Xiu-Juan Yan,Sheng-Liang Chen 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.3

        Background/AimsStigma related with antidepressants is prevalent in patients with functional dyspepsia. It affects medication compliance and efficacy. Herbal medicine acquired a deep-rooted cultural identity in relieving dyspeptic symptoms in Asians. The research was designed to compare the effectiveness of Zhizhu Kuanzhong capsules (ZZKZ) versus doxepin hydrochloride (doxepin) on alleviating stigma and medication nonadherence among patients with refractory FD (rFD). MethodsPatients with rFD from February 2021 to February 2022 were randomly allocated to receive either doxepin (n = 56) or ZZKZ (n = 57) combined with omeprazole for 4 weeks. Medication possession ratio (MPR), the disease- and medication-associated stigma were analyzed. The scales were utilized to assess dyspeptic symptoms (Leeds Dyspepsia Questionnaire) and psychological conditions (Generalized Anxiety Disorder Questionnaire and Patient Health Questionnaire). ResultsThe MPR values for ZZKZ were significantly higher than those for doxepin (P < 0.001). The stigma scores decreased in ZZKZ group while increased in doxepin group compared to baseline after treatment. The proportion of patients showing ZZKZ-associated stigma was significantly lower than doxepin-associated stigma (P < 0.001). The MPR values were negatively correlated with post-treatment stigma scores in both groups (P < 0.001). Dyspeptic symptoms and psychological condition were improved in both groups after treatment, with no significant difference on post-treatment Leeds Dyspepsia Questionnaire, Generalized Anxiety Disorder Questionnaire, or Patient Health Questionnaire scores between 2 groups. ConclusionZZKZ is superior to doxepin in alleviating stigma and medication non-adherence, with comparable efficacy in improving dyspeptic symptoms and psychological condition of patients with rFD.

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