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Immobilization with Ketamine HCI and Tiletamine-Zolazepam in Cynomolgus Monkeys
Myung-cheol Kim,Sung-hyeok Hong,Soo-jin Lee,Young-suk Kim,Jae-il Lee 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
with Ketamine HCl and Tiletamine-Zolazepam in Cynomolgus MonkeysJae-il Lee, Sung-hyeok Hong, Soo-jin Lee, Young-suk Kim and Myung-cheol Kim*Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, KoreaReceived March 4, 2003 / Accepted July 2, 2003J. Vet. Sci. (2003), 4(2), 187-191JOURNAL OFVeterinaryScience*Corresponding author: Myung-cheol Kim Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea Tel: +82-42-821-6757, Fax: +82-42-822-4216 E-mail: mckim@cnu.ac.kr
( Myung Jin Lee ),( Kye Hyung Kim ),( Jong Youn Yi ),( Su Jin Choi ),( Chung Jong Kim ),( Nak Hyun Kim ),( Kyoung Ho Song ),( Pyoeng Gyun Choi ),( Ji Hwan Bang ),( Wan Beom Park ),( Eu Suk Kim ),( San 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus Myung Jin LEE1, Kye-Hyung KIM1, Jongyoun YI2, SuJin CHOI1, Chung-Jong KIM1, Nak- Hyun KIM1, Kyoung-Ho SONG1, Pyoeng Gyun CHOI1, Ji-Hwan BANG1, Wan Beom PARK1, Eu Suk KIM1, Sang-Won PARK1, Hong Bin KIM1, Nam Joong KIM1, Myoung- Don OH1 Seoul National University College of Medicine, Korea1, Pusan National University School of Medicine, Korea2 Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel Bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV). No effective antiviral therapy is proven yet, but clinical use of ribavirin (RBV) has been tried. We investigated the antiviral effect of RBV against SFTSV in vitro. Methods: To test for cytotoxicity of RBV, Vero cells were treated with different concentrations of RBV (3.90 to 500 μg/mL, two-fold dilution) and analyzed by cell viability MTS assay 48h post-infection. To determine antiviral activity of RBV against SFTSV, Vero cells were infected with SFTSV strain Gangwon/Korea/2012 at 100 TCID50 (50% tissue culture infective dose) per well in a 96-well plate, and RBV was added at the concentrations showing no or minimal cytotoxicity. Viral RNAs were extracted from the culture supernatants and quantifi ed using one-step real-time reverse transcription- PCR to amplify the partial large segment of SFTSV. Statistical analysis was done by one-way ANOVA with Tukey`s post hoc test. Results: Cytotoxicity due to RBV was not observed at RBV concentration =31.3 μg/ mL. Viral RNAs at 24h post-RBV treatment were reduced with increasing RBV concentrations (1-32 μg/mL), compared with those of mock-treated cells (P <0.01, Figure). Half maximal inhibitory concentration (IC50) of RBV was 3.69 μg/mL at 24h post-RBV treatment. Conclusions: Our study shows that RBV has antiviral effect against SFTSV in a dose-dependent manner. Further studies are required to evaluate the effi cacy of RBV in SFTS.
박지숙,이민진,정재원,김미혜,이서연,지윤미,한준호,김유학,공명석,한광현,노희명 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2
It is important to interpret the soil chemical properties in order to effectively manage the farmland. This study was conducted to investigate the soil chemical properties of upland soybean field according to the soil series at 32 upland fields located in the parts of Gangwon-do. Soil sampling sites were selected by using the National Statistics DB and KSIS DB that is a soil environment information system provided by the Rural Development Administration. Soil samples were collected from 0~15 cm of top soil before seeding or transplanting, air-dried, passed through a 2 mm sieve, and analyzed for soil pH, EC, organic matter, available phosphorus (P2O5), exchangeable potassium, exchangeable calcium and exchangeable magnesium. The average chemical properties have exceeded the each nutrient optimum range level of RDA, except the organic matter in experimental soil 2015. And despite application of conventional fertilization, each soil series nutrient contents were change respectively. The results of this study suggest that conventional fertilization should be applied based on the analysis about the amount of accumulated nutrient contents in the soil.
Lee, Gun Sang,Lee, Myung Ki,Kim, Woo Jae,Kim, Ho Sang,Kim, Jeong Ho,Kim, Yun-Suk The Korean Neurosurgical Society 2017 Journal of Korean neurosurgical society Vol.60 No.1
Objective : We assessed the surgical results of bipolar release in 31 adult patients with uncorrected congenital muscular torticollis (CMT) and more than 12 months of follow-up. Methods : Thirty-one patients underwent a bipolar release of the sternocleidomastoid muscle (SCM) and were retrospectively analyzed. The mean follow-up period was 14.9 months (range, 12-30). The mean age at time of surgery was 30.3 years (range, 20-54). Patients were evaluated with a modified Lee's scoring system, cervicomandibular angle (CMA) measurement, and a global satisfaction rating scale using patient self-reporting. Results : The modified Lee's scoring system indicated excellent results in 4 (12.9%) patients, good in 18 (58.1%), and fair in 9 (29.0%) at the last follow-up after surgery. The improvements in neck movement and head tilt were statistically significant (p<0.05). The preoperative mean CMA was $15.4^{\circ}$ (range, 5.4-29.0), which was reduced to a mean of CMA of $6.3^{\circ}$ (range, 0-25) after surgery (p<0.05). The global satisfaction rating scale was 93.7% (range, 90-100). A transient sensory deficit on the ipsilateral lower ear lobe was noted in three cases. No significant permanent complications occurred. Conclusion : Bipolar release of the SCM is a safe and reliable technique for the treatment of CMT in adults.
이재일,이수진,김영석,김명진,조성환,신상태,이영원,김명철 충남대학교 수의과대학 동물의과학연구소 2003 動物醫科學硏究誌 Vol.11 No.-
A five years old female Shih-tzu was referred to the veterinary medical teaching hospital at Chungnam national university with soft bloody diarrhea and tenesmus. On rectal palpation, solid mass was palpated in colorectal region. In radiographs, small intestine was deviated cranially, descending colon and rectal junction were deviated caudoventrally in lateral projection of the abdomen. In ultrasonographs, hypoechoic nodulation of mesenteric lymph node in colorectal junction, mixed echoic thickening of colorectal wall and irregular margination were observed. Rectal endoscopy revealed that colorectal men was partially obstructed due to compression of the mass. Also, severe ulceration, inflammation and hemorrhage were also observed in descending colon. The mass was resected through the laparotomy. In histopathology, it was diagnosis of lymphoma in the colorectal junction.
소형 풍력발전시스템을 위한 계통연계형 인버터에 관한 연구
李大東,沈在明,張錫九 한밭대학교 2004 한밭대학교 논문집 Vol.21 No.-
We imported technology from abroad and studied grid connected type wind power generation owing to the lack of technology, but nowadays we conduct researches in many quarters because of national supporting policy. However, the research speed is delayed by burden for research expense which wind power generation is huge. Therefore, in order to experiment on various kinds of the wind turbine, generator, and converter easily, the development of wind power system is demanded powerfully among research workers. In this paper, in order to satisfy this need, I suppose a new simulation development environment. The electric power generated by wind is changing, so by using the converter, schedule electric power must be provided. Therefore, in this paper, I explained an element of the converter of the wind power generation system by showing two examples. First, Diode rectifier and current controlled voltage source inverter by using IGBT(Insulated Gate Bipolar Transistor) element was used in the wind power generation system. Second, rectifier for control by using IGBT and current controlled voltage source inverter by using IGBT element was connected the grid. Simulation for two examples of grid connected type wind power generation system uses PSCAD/EMTDC and analyzed the result.
大邱近郊에 飼育되는 乳牛의 第 1 胃 內容物의 調査 分析 : pH, 纖毛蟲 및 揮發性脂肪酸 ph, Ciliate Protozoa and Volatile Fatty acids
李熙碩,邊明大,咸泰守 경북대학교 1981 새마을 硏究論叢 Vol.1 No.-
The Content of rumen were compared between two groups (A and B) of dairy cow fed different rations. Group A were fed on ration consisted exclusively of concentrates, and Group B were fed on ration consisted mainly of roughage. 1. The pH of content in the rumen showed that group A was 6.9 and group B was 6.5 on the average. 2. Total number of ciliates of both A and B groups on the average per ml showed normal range, displaying somewhat increased in group A than group B. Ten genera or sub-genera and twenty-five species of ciliates were detected from the content of the rumen both A and B group of dairy cow. Among them Betehella was detected for the first in Korea. Entodinium simplex keeps the highest appearance rate of all species of ciliates, showing above 60 per cent of them all, and the others showing below 7 per cent on average. 3. There was no significant difference in volatile fatty acid(VFA) concentration of the contents of the rumen between two groups. When the VFA composition of the contents of the rumen was compared, the acetic acid content was significantly higher (P<0.05) whereas the propionic acid content was significantly lower (P<0.05) in group A than in those of group B.
全北大學校 綜合計劃(Master Plan)에 關한 硏究(Ⅰ)
李鍾純,張明洙,洪錫杓,朴漢圭 全北大學校 1977 論文集 Vol.19 No.-
This report outlines a ten-year(1976-1986) academic and physical development plan of Jeonbug National University. It was prepared over a period of ten months from April, 1976, to February, 1977, by a committee of five professors under the supervision of Dr. Chong Soon Lee. For a final report, the committee not only reviewed the past trend and patterns in the University's development and its present structures and conditions, both academic and physical, but also constantly consulted with Dr. Chong Supp Shim, president, the faculty, and experts in the field through meetings and questionaires. Consultation with them was paticularly needed in envisioning the future directions and possibilities for developing the University. The report presented here is a version revised and approved by the deans council of the University. Since its foundation in 1951, Jeonbug National University has grown from a small provincial institution into a full-scale national university. It now comprises seven colleges and three graduate schools, the students currently enrolled numbering around 5,500 and the faculty and administrative staff consisting of 750 employees. In keeping with the rapid growth of the nation and the governmental emphasis on developing provincial universities, the University is expected within ten years to develop into an academic institution consisting of eight colleges and six graduate schools. The number of undergraduate departments will increase from 40 to 61, and the number of students in attendance will amount to 10,000. In order to cope with this rapid increase in the number of departments and students, the academic plan of this report preseents a time-table of setting up new departments and makes a proposal for restructuring the University's academic and administrative systems. It also recommends that with the inception of the Research Foundation research activities will be systemitized and coordinated around ten major research institutes at the University. The physical development plan of the University has been in urgent need. The planning committe laid out a road construction plan mapping the entrances and major traffic routes on the campus. It also made proposals as to future building sites, centering around the central library under construction. The Medical School and its hospital, now in downtown Jeonju, are planned to be built on the 2nd campus east of the main campus. The University High School is also planned to move to the eastern part of the main campus. Besides the further construction of classroom and laboratory buildings, the University plans to construct an auditorium, an audio-visual center, a museum, a gymnasium, a new administration building, and other facilities. For the completion of these buildings, the estimated cost will amount to 200 billion won in total.