운동부하검사로 유발된 여성의 협심통증에 대한 예비연구

최명애,안경애,추진아,최윤식 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.2

Purpose : Women have been often underdiagnosed and undertreated when they have as high mortality as men of ischemic heart disease, such as angina. One of the reason of women's under treatment is associated with either vague, non-traditional symptoms or longer delay in seeking professional help when they experience ischemic heart disease. This study was conducted to investigate the characteristics of women's anginal pain induced by the treadmill test and to explore the potential relationship(s) between anginal pain and other psycho-physiologic factors. Method : Of 22 female patients referred to treadmill test, 7 with positive finding participated in this study. Anginal pain in the past was analyzed by Rose questionnaire, whereas anginal pain induced by the treadmill test was identified by McGill pain scale, visual analogue scale and present pain index. Results : Women expressed more heaviness than sharp pain, and complained splitting more often than subjects in previous study that included both men and women. Pain intensity by VAS 3.64±3.94, Pain rating index was 5.14±7.29, present pain index was 1.57±1.81, duration of pain was 5.14±4.8 min. Exercise intensity was 6.0±4.63 METs, exercise duration was 364.29±141.39 sec, ST change was -2.0mm and rate of perceived exertion was 16.29±2.06. The relationships between pain intensity and pain duration, ST segment changes were significant. Correlation among pain measures was significant. Conclusion : Generalization of these pilot findings may be inappropriate, and therefore, further larger study is needed.

협심증이 의심되어 운동부하검사를 받은 여성들의 흉통에 관한 내용분석

최명애,이명선,안경애,임은옥 성인간호학회 2002 성인간호학회지 Vol.14 No.3

Purpose: Experience of chest pain may be different in women from that of men and this discrepancy may cause misdiagnosis of angina contribute to mortality by this disease in women. The purpose of this study was to analyze the characteristics of chest pain and responses to the symptoms in women. Method: A content analysis was conducted with interviewed data obtained from women who underwent the treadmill test Result: Seven major categories were identified from this content analysis: attributes of chest pain; accompanied symptoms; precipitating factors; relief strategies; family support; communication with physicians; and effects of chest pain on their lives. Characteristics of pain were described as heaviness, tightness, heating sensation, tearing, and others. Duration and intensity of pain varied in a wide range. Radiating pain presented in 9 patients, and the locations of radiation were throat, neck, shoulder arm and fingers. Women tended not to respond actively to their chest pain, and didn't get appropriate support either from their family or from their physicians when they reported chest pain. Conclusion: Women express non-typical as well as typical patterns of pain when they experience chest pain. Clinicians have to consider the variability of symptoms when they assess women with suspicions of angina.

Dexamethasone 치료기간 중의 DHEA 투여가 쥐의 뒷다리근 질량에 미치는 영향

최명애,신기수,이은주,안경주 대한기초간호자연과학회 2001 Journal of korean biological nursing science Vol.3 No.1

The purpose of this study was to determine the effect of DHEA with dexamethasone on body weight and wet weight and relative weight of atrophied hindlimb muscles induced by dexamethasone treatment. 200~225g Wistar rats were divided into control(C), dexamethasone(D), dexamethasone and DHEA(DDH) groups. Dexamethasone was injected daily at a dose of 5mg/kg. DHEA was administered daily at a dose of 5mg/kg by oral ingestion during 7days. The data were analyzed by Kruskal-Wallis test and Mann-Whitney U test using the SPSSWIN 9.0 program. Body weight and muscle weight of plantaris and gastrocnemius of dexamethasone group decreased significantly compared with that of control group. Muscle weight of plantaris of DDH group increased significantly compared with dexamethasone group. Body weight of DDH group decreased significantly compared to control group, but relative weight of plantaris and gastrocnemius of DDH group increased significantly compared to control group. Based on these results, it can be suggested that DHEA administration during dexamethasone treatment can increase weight of atrophied plantaris muscle induced by dexamethasone treatment.

기초간호자연과학의 병태생리학, 병원미생물, 약물의 기전과 효과 내용별 필요도에 대한 연구

최명애,변영순,서영숙,황애란,김희승,홍해숙,박미정,최스미,이경숙,서화숙,신기수 대한기초간호자연과학회 2000 Journal of korean biological nursing science Vol.2 No.1

The purpose of this study was to define the content of the requisite knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs needed for clinical knowledge for nursing practice. Contents of knowledge on pathological physiology, clinical microbiology, and mechanisms and effects of drugs were constructed from syllabus of basic nursing subjects in 4 colleges of nursing, and textbooks. The degree of need of 72 items was measured with a 4 point scale. The subjects of this study were college-graduated 136 nurses from seven university hospitals in Seoul and three in Chonnam Province, Kyungbook Province, and Inchon. They have been working at internal medicine ward, surgical ward, intensive care unit, obstetrics and gynecology ward, pediatrics ward, opthalmology ward, ear, nose, and throat ward, emergency room, rehabilitation ward, cancer ward, and hospice ward. The results were as follows : 1. The highest scored items of the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs necessary for nursing practice were side effects of drugs, anticoagulants, mechanisms of drugs, antihypertensive drugs, tolerance and addiction of drugs, interactions among drugs, hospital infection in the order of importance. The lowest scored item was structure of microrganisms. 2. The highest order of need according to unit was repair in tissue injury unit, definition·etiology·classification of inflammation in inflammation unit, trasplantation and immunologic response in alterations in immunity unit, thrombus and thrombosis in disorders of cardiovascular function unit, gene disorders in genetic disorders unit, hospital infection in infection unit, virus in microrganisms unit, side reactions of drugs in introduction unit, anticonvulsants in drugs for central nervous system unit, local anesthesia in anesthesia unit, anticoagulants in drugs for cardiovascular system unit, anti-inflammatory drugs in antibiotics unit, anti-ulcer drugs in drugs for digestive system unit, and bronchodilators in drugs for respiratory system unit. 3. The common content of the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs needed for all clinical areas in nursing were side effects of drugs, anticoagulants, interactions among drugs, and hospital infection. However, the degree of need of each pathological physiology, clinical microbiology, and mechanisms and effects of drugs was different depending on clinical areas. 4. Significant differences in the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs necessary for nursing practice such as tissue changes due to injurious stimuli, degenerative changes of tissue, alterations in metabolism of carbohydrates, ischemia, hyperemia and congestion, hospital infection, structure of microorganism, classification of microorganism, bacteria, virus, antidepressants, antipsychotic drugs, antiemetic drugs, antiparkinsonism drugs, antianxiety drugs, antibiotics, tuberculostatics, antiviral drugs, antifungal drugs, parasiticides, antiulcer drugs, antidiarrheais, and anti constipation drugs were shown according to the work area. 5. Significant differences in the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs necessary for nursing practice such as transplantation and immunologic response, alterations in the metabolism of uric acid, structure of microorganism, classification of microorganism, immunosuppresants, drugs for congestive heart failure were demonstrated according to the duration of work. Based on these findings, all the 72 items constructed by Korean Academic Society of Basic Nursing Science should be included as contents of the knowledge of pathophysiology, clinical microbiology. and mechanisms and effects of drugs

과민성 장 증후군의 증상 경감을 위한 비약물적 접근 고찰

최명애,김금순,안경주,채영란,최정안,홍해숙,박미정,이경숙,신기수,정재심 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.2

There have been many trials of clinical efficacy of multicomponent and single component treatments for irritable bowel syndrome(IBS). We reviewed effects of non phamacological treatments in the IBS. Though the efficacy of multi-component approaches was unclear, several results suggest that cognitive behavioral therapy was effective in improving gastrointestinal symptoms of IBS. As a single component, cognitive therapy and relaxation with or without biofeedback could improve the symptoms and psychological health of IBS patients. Yoga, meditation, self-help information and hypnotherapy could be applicable to IBS.

계획되지 않은 아동의 입원시 정보제공이 어머니 스트레스 대처에 미치는 효과

최명애,박승현,권원경,김선구,안혜영,김윤경 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.13 No.1

The purpose of this study was to explore the effect of informational intervention on coping of mother's stress in unplanned childhood hospitalization. Thirty four mothers of the hospitalized children, 24 months to 60 months old, were randomly assigned to experimental and control group. Child behavioral information and parental role information was given to experimental group by booklet and cassette tape. The state-trait anxiety was measured within 12 to 24 hours following hospitalization, the state anxiety was measured during from 24 hours to 48 hours, and the parent participation with care of children, and the parent support during invasive procedures was measured during 48 hours to 72 hours after hospitalization. The data was collected from May, 1997 to October, 1998 at B hospital in Seoul. Data was analyzed with X²-test, non paired t-test, ANCOVA test and Wilcoxon test using SAS program. Results were obtained as follows: 1. There were no difference in the state anxiety during the period of hospitalization and after discharging from hospital between experimental and control group. 2. Experimental group showed significantly higher scores on the parent participation with care of children than control group(P=0.03). 3. The parent support during invasive procedures of experimental group was significantly greater than that of control group(P=0.0167). The results suggest that information intervention regarding child behavioral information and parental role information may enhance both the parent participation with care of children and the parent support during invasive procedures.

당뇨병 환아의 당뇨캠프 프로그램 종료후 시간경과에 따른 우울,자기효능감,자기존중감의 변화

최명애,유주화,한경자,안혜영 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.13 No.1

The purpose of this study was to explore the effect of diabetic camp program on depression, self-efficacy and self-esteem of the juvenile diabetic patients who had participated diabetic camp program at Seoul and Kyung In area from August 5 to August 9, 1995. It was compared the change of depression, self efficacy and self-esteem right after participating the program, 6 and 12 month. Nursing staffs explained them how to respond to the questionnaire of depression, self-efficacy and self-esteem. The questionnaire of depression, self-efficacy and self-esteem was especially developed by both dibetes mellitus nurse specialist and pediatric nursing progessors for this study. Elementary school students are asked to response yes or no questionnarie. We asked the 5 lidert scale questionnaire for the both middle and high school students. Paired t-test was used to compare the difference right after the diabetic camp program, 6 and 12 month. Depression decreased right after participating the program, while self-esteem increased significantly following the program in elementary school students. And after the camp, there was o change in depression and self-esteem scores 6 and 12 month. There was no change in self-esteem and self-efficacy right after the camp, 6 and 12 month in middle and high school students. The result suggests that diabetic camp program could be the effective way to decrease depression and to increase self-efficacy and self-esteem, which has continued effect of diabetic camp program on depression, self-efficacy and self-esteem after 6 and 12 onth of the diabetic camp.

주기적인 운동이 뒷다리 부유에 의해 유발된 쥐의 뒷다리근 위축경감에 미치는 영향

최명애,신기수 대한기초간호자연과학회 1999 Journal of korean biological nursing science Vol.1 No.1

The purpose of this study was to determine the effect of periodic low-intensity exercise during hindlimb suspension on the mass, relative weight, myofibrillar protein content in soleus, plantaris and gastrocnemius muscles. To examine the effectiveness of periodic low-intensity exercise on mass, and myofibrillar protein content of hindlimb muscles, adult female Wistar rats were suspended(HS) and half of these rats walked on a treadmill for 45min/day(15 min every 4h) at 5m/min and a 15˚ grade(HS-EX). Soleus wet weight was 33.51% significantly smaller(p<0.005) and relative soleus weight of hindlimb suspended rats was 31.96% smaller(p<0.005) compared with those of control rats following seven days of hindlimb suspension. Plantaris wet weight was 7.5% smaller(p<0.01) and relative plantaris weight was 11.83% smaller(p<0.05) compared with those of control rats following seven days of hindlimb suspension. Gastrocnemius wet weight was 11.31% significantly smaller(p<0.005) and relative gastrocnemius weight was 17.13% significantly smaller(p<0.005) compared with those of control rats following seven days of hindlimb suspension. Soleus wet weight while increased by relative soleus weight increased by 25.13%, 27.59% each through periodic low intensity exercise during hindlimb suspension(p<0.05, p<0.05). Plantaris wet weight and relative plantaris weight increased by 1.04%, 10.98%(p<0.05) each, and gastrocnemius wet weight and relative gastrocnemius weight increased by 1.98%, 12.02%(p<0.05) each through periodic low intensity exercise during hindlimb suspension. Wet weight of soleus, plantaris and gastrocnemius in HS-EX rats did not recover to control level. Myofibrillar protein content of soleus, plantaris and gastrocnemius was 48.24%, 40.85% and 37.33% significantly smaller(p<0.005) respectively compared with those of control rats following seven days of hindlimb suspension. Myofibrillar protein content of soleus, plantaris and gastrocnemius increased by 40.68%, 25.07% and 17.93%(p<0.005) each through periodic low intensity exercise during hindlimb suspension. Myofibrillar protein content of soleus, plantaris, and gastrocnemius in HS-EX rats did not recover to control level. The results suggest that periodic low intensity exercise can attenuate hindlimb muscle atrophy induced by hindlimb suspension.

스테로이드 치료 후 회복기의 규칙적인 운동이 쥐의 스테로이드 유발성 위축 뒷다리근에 미치는 영향

최명애,변영순,황애란,김희승,홍해숙,최스미,서화숙,이경숙,박미정,신기수,안경주,이윤경,임지회 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.1

This study was conducted to determine whether low intensity regular exercise following steroid treatment could attenuate steroid-induced muscle atrophy. Thirty-eight Sprague-Dawley rats weighing 165~175g were divided into six groups;control group(C), dexamethasone administration group(D), sedentary after normal saline administration group(C+Se), exercise after normal saline administration group(C+Ex), sedentary group after dexamethasone administration(D+Se), exercise group after dexamethasone administration(D+Ex). Either dexamethasone(5mg/kg) or normal saline was injected for 7days accordingly. Exercise was started at 10m/min on the 10?grade treadmill and gradually increased up to 15m/min by the 7th day for 60minutes/day(20min×3). The data were analyzed by Kruskal-Wallis test and Mann-Whitney U test using the SPSS WIN 9.0 program. Body weight, muscle weight and myofibrillar protein content of both plantaris and gastrocnemius, Type I, II muscle fiber cross-sectional area of plantaris, and Type II muscle fiber cross-sectional area of gastrocnemis in D group were significantly lower than those of C group(p<.05) respectively. Hindlimb muscle weight, myofibrillar protein content of both plantaris and gastrocnemius, Type I muscle fiber cross-sectional area of soleus and Type I, II muscle fiber cross-sectional area of plantaris in D+Ex group tended to increase compared to those of D+Se group. Myofibrillar protein content of both plantaris and gastrocnemius, Type I muscle fiber cross-sectional area of plantaris in D+Ex group tended to increase compared to those of C+Se group. Based on these results, it is suggested that regular low-intensity exercise during recovery period after steroid treatment might facilitate the recovery from steroid-induced muscle atrophy.

석·박사 학위논문에서 생리적 변수를 다룬 연구에 대한 분석 : 1962년부터 1996년까지 발표된 국내 학위논문을 중심으로 with reference to the thesis published in Korea from 1962 to 1996

최명애,김주현,박미정,최스미,이경숙 대한기초간호자연과학회 2000 Journal of korean biological nursing science Vol.2 No.2

Objectives : The studies in biological, behavioral and psychosocial perspectives in nursing research are fundamental in the balanced development of nursing knowledge. Many nursing researchers have placed a strong emphasis on developing psychological and behavioral aspects of nursing knowledge as is evidenced by the large body of research in these areas. However, the paucity of nursing research using the principles of biological science for measurements and techniques have often invited open criticism by many nursing researchers. This study attempts to characterize the researches performed in master and doctoral thesis which used physiological variables. Methods : We analyzed masters' thesis from 1962 to 1996 and doctoral thesis from 1982 to 1996 listed in CD from Korean Nurses Association. Results : Out of 3060 masters' thesis from 1962 to 1996, 342 (11.2%) thesis used physiological variables whereas 43 (10.1%) doctoral thesis used physiological ones. Number of thesis with physiological variables was the highest in Seoul National University for masters' thesis whereas for the doctoral thesis the number was the highest in Yonsei University. The research subjects in these thesis with physiological variables were mostly patients (53.5% in masters' and 69.8% in doctoral). Master's thesis often conducted either nonexperimental or survey research (69.9%) whereas experimental research design prevailed vital signs(l81 thesis), blood tests(133), body composition(124), microorganisms(74), gastrointestinal functions(36), lab test(33), drug(2l), urinary functions(20), movement(l7), Apgar Score(l5), reproductive functions(9), skin related functions(6), body fluid and electrolytes(4), parasite(4), metabolism(3), and sensory(1). Among the 338 master' thesis which studied the common nursing concepts such as anxiety, pain, stress, and depression, 48(14.2%) thesis utilized physiological variables while 15 out of 35 doctoral thesis addressed these concepts using physiological variables. Conclusion : In summary, our results indicate that despite the large amount of nursing research performed over the last decades, there are a few nursing researches done with physiological variables either in masters' or doctoral thesis. To enrich nursing knowledge with different perspectives of nursing including especially biological ones, the efforts have to be made to conduct bionursing science research.