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한국에서 메스암페타민 남용 또는 의존 환자의 인격장애에 관한 연구
김소영,권성민,조성남,권도훈,강병조,김형태 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.2
연구 목적 : 메스암페타민 남용 또는 의존이 없는 군과 있는 군 사이의 인격장애의 유병율을 알아보고, 메스암페타민 남용 또는 의존군에서 동반 인격장애가 그들의 전반적 기능 및 일반적 특성에 어떠한 영향을 미치는지 알아보고자 하였다. 방 법 : 대상은 정상대조군에서 메스암페타민 남용 또는 의존이 없는 50명과 정신병원에 입원한 메스암페타민 남용 또는 의존환자 50명이었다. 메스암페타민 남용과 전반적 기능에 대한 평가는 DSM-Ⅳ에 의거하였고, 인격장애를 평가하기 위해 대상군 모두에서 PDQ-4+를 시행하였다. 결 과 : 정상대조군은 34%에서 적어도 1개 이상의 인격장애를 나타내었으며, 한 사람 당 평균 3.94개였다. 메스암페타민 남용 또는 의존군은 64%에서 적어도 1개 이상의 인격장애를 보였으며, 한 환자 당 평균 4.72개였다. 메스암페타민 남용 또는 의존군에서 동반 인격장애의 유무는 시작 연령, 사용 용량, 그리고 입원 또는 구치 횟수와는 관련성이 없는 것으로 나타났으나, 3개 이상의 동반 인격장애를 가질 경우, 그렇지 않은 군에 비해 전반적 기능이 떨어졌다. 결 론 : 본 연구 결과, 우리나라에서도 일반인에 비해 물질사용장애 환자에서 인격장애를 동반할 가능성이 높으며, 물질사용장애 환자 중에서도 인격장애를 동반한 군이 그렇지 않은 군에 비해 전반적으로 기능이 떨어진다는 결론이 가능하게 되었다. Objectives : The purpose of this study was to examine the prevalence of personality disorders between normal control group and hospitalized methamphetamine abuse or dependent patients and, among the latter, the influence of comorbid personality disorder on their global assesment function and general characteristics. Methods : Subjects were 50 non-methamphetamine abuse or dependent persons in the general population group and 50 methamphetamine abuse or dependent patients admitted to the psychiatric hospital. Methamphetamine abuse or dependence and the global assesment function were diagnosed according to DSM-Ⅳ, and the presence of personality disorder was assessed with the PDQ-4+. Results : In the normal control group, 34% of subjects had at least one personality disorder and the average number of personality disorder was 3.94 per person. In the methamphetamine abuse or dependent group, 64% of the patients had at least one personality disorder and the average number .of personality disorder was 4.72 per patient. The presence of comorbid personality disorder were not associated with onset age, use dosage and the number of admission or arrest among the methamphetamine abuse or dependent group. But, when methamphetamine abuse or dependent patients had more than three personality disorders, the global assessment function was impaired. Conclusion : In our study, substance use disorder patients had the higher possibility of comorbid personality disorder in Korea, and among substance use disorder patients, those with comorbid personality disorders were associated with the greater global impairment.
악성종양환자와 정상인이 발성한 모음의 좁은대역 스펙트럼값의 상관계수와 절대차이합 비교
양병곤,왕수건,조철우,김형순,김은지,권순복 한국음성과학회 2003 음성과학 Vol.10 No.4
The objective of this study was to examine two new parameters by which we could screen people with malignant vocal folds. The new parameters were the difference sums and Pearson correlation coefficients between adjacent pairs of intensity level matrices of narrow-band spectra. Audio files from the Korean Disordered Speech Database were analyzed by Praat, a speech analysis softWare, to obtain matrices of 400 intensity levels at 16 time points of each sustained vowel spectra. We limited our study to 12 normal subjects and 20 patients with malignant vocal folds who recorded at least three Korean vowels at a sound-proofed booth in Busan National University Hospital. Results indicated that the average coefficients of the abnormal subjects were much lower than those of the normal subjects while the average difference sums of the patients were much higher than those of the normal ones. Also, we found that the degree of the malignancy of the vocal folds was related to the coefficients and sums. However, some subjects at the initial stages of cancerous vocal folds yielded almost comparable coefficients and difference sums to those of the normal speakers. Further studies on larger databases will be desirable to set certain criteria or threshold levels for screening people with vocal fold diseases.
Plant Growth-promoting Activity of Acremonium strictum MJN1 Isolated from Roots of Panax ginseng
Lim, Hyung-Bum,Chung, Yang-Jo,Bae, Ju-Yun,Kim, Dong-Jin,Kwon, Hyung-Jin,Lee, In Hyung,Chung, Byung-Chul,Lee, Woong-Sang,Suh, Joo-Won 한국응용생명화학회 2000 Journal of Applied Biological Chemistry (J. Appl. Vol.43 No.2
The plant growth-promoting activity of Acremonium strictum MJN1 isolated from roots of Panox ginseng was explored. The myceliaI extract of A. strictum MJN1 enhanced the rice seedling growth by 14.5 and 9.0% in the dried weight of shoots and roots, and the growth of red pepper by 54 and 85% in the top length and the dried weight in pot experiments, respectively. The plant growth-promoting substances in the myceliaI extract of Acremonium strictum MJN1 were identified as D-adenosine and glycerol. Both commercial D-adenosine and glycerol also promoted significantly the rice seedling growth but, unlike the mycelial extract of A. strictum MJN1, hardly affected the yields of plants grown in pots or field. Therefore, it is possible that other plant growth-promoting substances are produced by A. strictum MJN1. However, this study shows that A. strictum MJN1 has a great potential as a biofertilizer.
A study of the structure in ZnO/MgO multilayer by using synchrotron x-ray scattering method
Jae Hyung Jo,Yoon Hwae Hwang,Dae-Young Kwon,Hyung Kook Kim 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.2I
We deposited a ZnO/MgO multi-layer thin film on a Nb-doped SrTiO3 substrate by using the pulsed laser deposition (PLD) technique. The structures of the ZnO and the MgO layers were characterized by using an X-ray diffraction experiment. We observed that the ZnO film had an a-axis orientation normal to the substrate with four families of crystallites whereas a typical ZnO thin film had a c-axis preferred orientation.
Effects of oxygen pressure on the crystalline of ZnO lms grown on sapphire by PLD method
Jae Hyung Jo,Hyung Kook Kim,Dae Young Kwon,Jin Sung Kwak,Tae-Bong Hur,Yoon-Hwae Hwang 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.47 No.2
We studied the effects of oxygen pressure on the crystallinity of ZnO films. ZnO films on sapphire(001) substrates were deposited by the pulsed laser deposition (PLD) technique and were grown at various oxygen pressures ranging from 5 mTorr to 150 mTorr to investigate the effect of ambient O2 pressure on the structural properties of the films. We found that the lattice constant along the c-axis and the crystallinity of ZnO films were sensitive to the O2 pressure.
조진호,김종호,권오형,김태균 한국방송공학회 1999 한국방송공학회 학술대회 Vol.1 No.1
This paper represents analysis of terrestrial DTV field test results over Taejon city area. Thirty three points were selected as measuring points Signal power, noise power, Segment Error Rate (SER) and equalizer performance was measured DTV video & audio quality was good over half of test sites. Equalizer could correct signal ghost and improve S/N up to 13.7dB
Kwon, Hyuk-Chan,Moon, Chang Hoon,Kim, Sung-Hyun,Choi, Hong-Jo,Lee, Hyung-Sik,Roh, Mee Sook,Hwang, Tae-Ho,Kim, Jae-Seok,Kim, Hyo-Jin Oxford University Press 2005 Japanese journal of clinical oncology Vol.35 No.9
<P><B>Objective:</B> The interferon-induced, double-stranded RNA-activated, protein kinase (PKR) is a key regulator of translational initiation, and plays an important role in the regulation of cell proliferation, apoptosis and transformation. The aim of this study was to evaluate the prognostic significance of PKR in lymph node negative rectal cancer.</P><P><B>Methods:</B> Forty-three patients with stage II rectal carcinoma who underwent potentially curative resection followed by post-operative adjuvant chemoradiation and 5-fluorouracil-based chemotherapy were investigated immunohistochemically using the monoclonal antibody TJ4C4. Overall scores for PKR expression were calculated based on staining intensity and immunoreactive tumor cell fraction. Clinical information, including tumor grade, carcinoembryonic antigen (CEA), disease-free survival (DFS) and overall survival (OS) was evaluated and compared with the degree of PKR expression.</P><P><B>Results:</B> The median follow-up duration was 53.2 months, and median patient age was 55 years (range 33–73). No relationships were found between PKR score and age, sex, tumor grade or CEA level; however, smaller tumors (≤5 cm) were associated with high PKR score (<I>P</I> = 0.025). When patients were subdivided into two groups based on the PKR score, the relapse rate was lower for those with a high PKR score (7.4 versus 43.8%, <I>P</I> = 0.008), and a significant difference was found between these two groups in terms of 5 year DFS (92.6 versus 55.6%, <I>P</I> = 0.0072) and 5 year OS (92.6 versus 57.7%, <I>P</I> = 0.0459). Other clinicopathologic variables were not related to clinical outcome.</P><P><B>Conclusion:</B> PKR expression levels were associated with disease recurrence, DFS and OS in lymph node negative rectal cancer patients.</P>