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윤헌영,정순욱,박희명,박철,정만복,김준영,한현정,황민,노병국,박상혁,장하영,박정윤 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1
A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary teaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 U/L), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasonographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.
스위치드 릴럭턴스 전동기를 위한 구동시스템의 역률개선과 고효율에 관한 연구
한대희,최준혁,윤용호,정동효,김도군,원충연 성균관대학교 2003 학술회의지원논문목록집 Vol.2003 No.-
Switched Reluctance Motor (SRM) offers the advantages of simple and robust motor construction, high speeds and high efficiencies over a wide operating range of torque and speed, excellent controllability. However, SRM has the disadvantages of high current harmonics, and low power factor because of a capacitor filter is inserted in the power converter and inductance of SRM is high, it has pulse waveform of current. This paper deals with an energy efficient converter fed SRM system with the reduced harmonics and improved power factor and with higher efficiency. The validity of the proposed scheme is verified via experiment. We are implemented the proposed control system using 8OC196KC micro-controller.
김태우,김승범,권혁찬,문선재,윤정훈,김형준,차인호,육종인,김진 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.1
Periosteal osteosarcoma is a distinct entity of malignant bone tumor with characteristic clinical, morphological, and histological features within the group of juxtacortical osteosarcoma. Periosteal osteosarcoma is predominantly located in the tubular long bones, and extremely rarely involving the jaws. A case of periosteal osteosarcoma of the right mandible is presented. A 27-year-old woman complained of the gingival swelling and bleeding tendency of the right posterior mandible. Clinical examination revealed a reddish brown strawberry-like swelling on the affected mucosa, which measured 1.5㎝×1.5㎝. The tumor was located on the lingual cortex of the mandible and extended into the surrounding soft tissues. Microscopically, the tumor consisted exclusively of atypical chondroblastic cells with a small osteoblastic area. A minimal bone marrow involvement was noted and the adjacent cortex was free of tumor. These findings suggested that the tumor originated from the periosteal cambium layer, which lies between the periosteal fibrous layer and the cortex of mandible.
Yoon, Hyuk Jin,Park, Myung Jun,Kim, Jung Seok,Park, Jung Jun Trans Tech Publications, Ltd. 2012 Advanced materials research Vol.566 No.-
<P>Railway journal box is designed to monitor the temperature and acoustic emission signal from the axle continuously. Fiber Bragg gratings (FBG) sensors are embedded inside of the journal box cover. Three types of journal box cover are designed such as front elbow coupler type, side hose type and side coupler type. Sensors and optical fiber are located on the predetermined positions engraved inside of the cover. Optical fiber egresses out of the surface and is protected in the protection tube. Among the three types of journal box cover, the side coupler model could be used most effectively.</P>
Yoon Hyuk-Jun,Jung Won Pill,Min Young Sil,Jin Fanxue,Bang Joon Seok,Sohn Uy Dong,Je Hyun Dong 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.2
In this study, we investigated the influence of galangin on vascular contractibility and to determine the mechanism underlying the relaxation. Isometric contractions of denuded aortic muscles were recorded and combined with western blot analysis which was performed to measure the phosphorylation of phosphorylation-dependent inhibitory protein of myosin phosphatase (CPI-17) and myosin phosphatase targeting subunit 1 (MYPT1) and to evaluate the effect of galangin on the RhoA/ROCK/CPI-17 pathway. Galangin significantly inhibited phorbol ester-, fluoride- and thromboxane mimetic-induced vasoconstrictions regardless of endothelial nitric oxide synthesis, suggesting its direct effect on vascular smooth muscle. Galangin significantly inhibited the fluoridedependent increase in pMYPT1 and pCPI-17 levels and phorbol 12,13-dibutyrate-dependent increase in pERK1/2 level, suggesting repression of ROCK and MEK activity and subsequent phosphorylation of MYPT1, CPI-17 and ERK1/2. Taken together, these results suggest that galangin-induced relaxation involves myosin phosphatase reactivation and calcium desensitization, which appears to be mediated by CPI-17 dephosphorylation via not PKC but ROCK inactivation.
Design of Autonomous Cruise Controller with Linear Time Varying Model
Hyuk-Jun Chang,Tae Kyun Yoon,Hwi Chan Lee,Myung Joon Yoon,Chanwoo Moon,Hyun-Sik Ahn 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.5
Cruise control is a technology for automatically maintaining a steady speed of vehicle as set by the driver via controlling throttle valve and brake of vehicle. In this paper we investigate cruise controller design method with consideration for distance to vehicle ahead. We employ linear time varying (LTV) model to describe longitudinal vehicle dynamic motion. With this LTV system we approximately model the nonlinear dynamics of vehicle speed by frequent update of the system parameters. In addition we reformulate the LTV system by transforming distance to leading vehicle into variation of system parameters of the model. Note that in conventional control problem formulation this distance is considered as disturbance which should be rejected. Consequently a controller can be designed by pole placement at each instance of parameter update, based on the linear model with the present system parameters. The validity of this design method is examined by simulation study.
Jun, Jin Hyuk,Jeong, Kyeong Sook,Lee, Tae-Jin,Kong, Sang Jun,Lim, Tae Hoon,Nam, Suk-Woo,Hong, Seong-Ahn,Yoon, Ki June 한국화학공학회 2004 Korean Journal of Chemical Engineering Vol.21 No.1
Nickel-calcium phosphate/hydroxyapatite catalysts have recently been reported to exhibit high activity and selectivity in partial oxidation of methane (POM). In this work the optimum composition was determined. The optimum mole ratio of Ca/PO₄ was around 10/6 and that of Ni/PO₄ was in a range from 1.0/6 to 3.0/6 with the optimum Ca/PO₄, and the activity could be related with the amount of metallic nickel. In a temperature range from ca.400 to 700K, an apparent autothermal reaction was observed to occur in some cases. This is due to the fact that the actual catalyst temperature is higher than the measured temperature, which comes from the exothermic nature of the reaction. The mixing sequence of the precursors during the catalyst preparation does little affect the catalyst activity and characteristics. Deactivation of the catalyst occurred slowly, but the catalyst could easily be regenerated. Moreover, the nickel-calcium phosphate/hydroxyapatite catalyst showed higher activity than the nickel-strontium phosphate catalyst.
The Effect of Luteolin on the Modulation of Vascular Contractility via ROCK and CPI-17 Inactivation
( Hyuk-jun Yoon ),( Dae Hong Kang ),( Fanxue Jin ),( Joon Seok Bang ),( Uy Dong Sohn ),( Hyun Dong Je ) 한국응용약물학회 2023 Biomolecules & Therapeutics(구 응용약물학회지) Vol.31 No.2
In this investigation, we made a study of the efficacy of luteolin (a flavonoid found in plants such as vegetables, herbs and fruits) on vascular contractibility and to elucidate the mechanism underlying the relaxation. Isometric contractions of denuded muscles were stored and combined with western blot analysis which was conducted to assess the phosphorylation of myosin phosphatase targeting subunit 1 (MYPT1) and phosphorylation-dependent inhibitory protein for myosin phosphatase (CPI-17) and to examine the effect of luteolin on the RhoA/ROCK/CPI-17 pathway. Luteolin significantly alleviated phorbol ester-, fluoride- and thromboxane mimetic-elicited contractions regardless of endothelial nitric oxide synthesis, implying its direct effect on smooth muscle. It also significantly alleviated the fluoride-elicited elevation in pCPI-17 and pMYPT1 levels and phorbol 12,13-dibutyrate-elicited increase in pERK1/2 level, suggesting depression of ROCK and PKC/MEK activity and ensuing phosphorylation of MYPT1, CPI-17 and ERK1/2. Taken together, these results suggest that luteolin-elicited relaxation includes myosin phosphatase reactivation and calcium desensitization, which seems to be arbitrated by CPI-17 dephosphorylation via ROCK/PKC inhibition.
Characterization of a Nickel-Strontium Phosphate Catalyst for Partial Oxidation of Methane
Jun, Jin Hyuk,Lee, Sang Jin,Lee, Seung-Hwan,Lee, Tae-Jin,Kong, Sang Jun,Lim, Tae Hoon,Nam, Suk-Woo,Hong, Seong-Ahn,Yoon, Ki June 한국화학공학회 2003 Korean Journal of Chemical Engineering Vol.20 No.5
A nickel-strontium phosphate catalyst was recently reported to exhibit high activity and selectivity in partial oxidation of methane(POM). Further characterizations hane been performed in the present work in order to better understand the characterizations of this catalyst. TEM showed that very fine nickel particles of a few nanometers of the size were present in the needle shape in the sample after the reaction. TPR showed the presence of three nickel species, reduced during the reaction. As the calcination time during the preparation increased, the total re-oxidation temperature became higher. This is considered due to larger crystallite size owing to the longer calcination, which results in a smaller amount of nickel coming out of the matrix to the surface.