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      • 개의 아토피 피부염에 대한 Leflunomide의 임상적 적용 1례

        홍은지,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        A Shih-tzu(8-year-old, castrated male) was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of relapsing pruritus, recurrent dermatitis. On the physical examination, generalized erythema, otitis externa, alopecia and lichenification were observed. Using Favrot's criteria for diagnishing atopic dermatitis, 7 criteria were satisfied out of 8 criteria. After treatment for infection, intradermal skin test was performed(positive allergen : Df, Dp). And then immunotherapy was performed, but clinical signs were not getting better. Next treatment of glucocorticoid shown little improvement of clinical signs, and adverse effect(diarrhea) was shown after cyclosporine application. So application of leflunomide which is used for human atopic dermatitis treatment in some case was planned. After 6 months of application of leflunomide, clinical signs were decreased gradually.

      • 무증상으로 발견된 담낭-담관 누공을 동반한 Mirizzi 증후군 1예

        홍진희,전태주,서지영,서동대,오태훈,신원창,최원충,신은아,김기환 인제대학교 2009 仁濟醫學 Vol.30 No.-

        Mirizzi's syndrome is a rare complication of the gallstone disease, characterized by narrowing of the common bile duct (CBD) due to chronic extrinsic compression of an impacted gallstone in the cystic duct or the neck of the gallbladder. The impacted gallstone may erode into the bile duct, causing cholecystocholedochal fistula. The patients generally have history of repeated attacks of jaundice and abdominal pain. But there is no report about asymptomatic Mirizzi syndrome with cholecystocholedochal fistula which were found incidentally. So herein we present our clinical experience with a case of asymptomatic Mirizzi syndrome with cholecystocholedochal fistula in a young female.

      • KCI등재

        생검펀치를 이용한 점액낭종의 절제

        홍은혜,최병재,이제호,최형준,손흥규,김성오 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.2

        점액낭종은 소타액선 분비관의 폐쇄나 파열로 타액이 저류되어 발생하는 연조직 부종이고, 비교적 높은 빈도로 발생하는 구강내 가성 낭종으로 스스로 파열되어 치유되기도 하지만 대개는 만성적으로 진행되어 몇 주에서 몇 달간 지속되기 때문에 치료가 필요하다. 점액 낭종의 발생시, 주변에 이환된 소타액선을 포함하여 제거하는 완전절제술 외에 재발율을 낮추기 위한 스테로이드의 국소적 주입, 냉동동결요법(cryotherapy), 미세조대술(micromarsupialization) 등의 여러 가지 치료방법이 제시되고 있다. 완전절제술의 한 방법으로 생검펀치(biopsy punch)를 이용할 수 있는데, 조작이 간편하고 출혈이 적으며 술 후 처치가 거의 필요없다는 장점이 있다. 이 증례는 점액낭종이 있고 행동 조절이 힘든 소아에서 생검펀치를 사용하여 점액낭종을 완전히 제거한 경우로, 양호한 결과를 얻었다. Mucocele is a clinical term of the localized superficial mucosal swelling caused by salivary retention after the obstruction or the rupture of minor salivary ducts. Various treatment methods have been suggested to lower its recurrence rate, including complete excision of lesion Biopsy punch can be used easily and simply for complete excision of mucocele. It has several advantages, such as convenience in use, low bleeding tendency, and nearly no requirements for post-operative management. In this case, biopsy punch was used for the removal of mucocele in an uncooperative child, which enable fast, simple and safe procedure, with a good result.

      • 식도발성의 숙련 정도에 따른 모음의 음향학적 특징과 자음 산출에 대한 연구

        최성희,최홍식,김한수,임성은,이성은,표화영 한국음성과학회 2003 음성과학 Vol.10 No.3

        Esophageal Speech uses the esophageal air during phonation. Fluent esophageal speakers frequently intake air in oral communication, but unskilled esophageal speakers are difficult with swallowing lots of air. The purpose of this study was to investigate the different of acoustic characteristics of vowel and consonants production according to the speech proficiency level in esophageal speech. 13 normal male speakers and 13 male esophageal speakers (5 unskilled esophageal speakers, 8 skilled esophageal speakers) with age ranging from 50 to 70 years old. The stimuli were sustained /a/ vowel and 36 meaningless two syllable words. Used vowel is /a/ and consonants were 18 : /k, n, t, m, p, s, c, ch, kh, th, ph, h, I, k', t', p', s', c'/. Fundamental frequency (Fx), Jitter, shimmer, HNR, MPT were measured with by electroglottography using Lx speech studio (Laryngograph Ltd, London, UK). 36 meaningless words produced by esophageal speakers were presented to 3 speech-language pathologists who phonetically transcribed their responses. Fx, Jitter, HNR parameters is significant different between skilled esophageal speakers and unskilled esophageal speakers (P<.05). Considering manner of articulation, ANOVA showed that differences in two esophageal speech groups on speech proficiency were significant; Glide had the highest number of confusion with the other phoneme class, affricates are the most intelligible in the unskilled esophageal speech group, whereas in the skilled esophageal speech group fricatives resulted highest number of confusions, nasals are the most intelligible. In the place of articulation, glottal /h/ is the highest confusion consonant in both groups. Bilabials are the most intelligible in the skilled esophageal speech; velars are the most intelligible in the unskilled esophageal speech. In the structure of syllable, 'CV+V' is more confusion in the skilled esophageal group, unskilled esophageal speech group has similar confusion in both structures. In unskilled esophageal speech, significantly different Fx, Jitter, HNR acoustic parameters of vowel and the highest confusions of Liquid, Nasals consonants could be attributed to unstable, improper contact of neoglottis as vibratory source and insufficiency in the phonatory air supply, and higher motoric demand of remaining articulation due to morphological characteristics of vocal tract after laryngectomy.

      • KCI등재

        상악 절치부에 매복된 다수 과잉치의 외과적 발거

        홍은혜,김성오,이제호,최형준,송흥규,최병재 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

        과잉치란 정상에 비해 많은 수의 치아를 일컫는 것으로 유치열기와 혼합치열기에 발생하며,여러 가지 임상적 문제를 일으킬 수 있다. 특히 상악 전치부의 과잉치는 상악 전치의 맹출 장애 및 전위,정중부의 치간 이개,치근 흡수,함치성 낭종 형성 등의 문제를 유발할 수 있으므로 조기에 진단하고,과잉치의 위치 및 수,형태에 따라 적절한 치료를 시행하는 것이 중요하다. 이 증례는 상악 전치부에 네 개의 과잉치가 영구치의 맹출을 방해하고 있는 경우로,발거 시 합병증을 최소화하기 위하여 두 단계로 나누어 발거하였다. 컴퓨터 단층 촬영에서 네 개의 과잉치가 주위의 영구치 맹출을 방해하고 있었고,그 중 두 개의 과잉치는 절치 치배에 매우 근접해 있었다. 네 개의 과잉치를 동시에 제거할 경우 영구 치배에 손상을 줄 위험이 있으므로 두 개의 역위 매복된 원추형의 과잉치만 먼저 발거하였다. 남은 두 개의 과잉치는 위치가 변화되기를 기다린 후 두 번째 발거 수술을 시행하여,주위 절치 치배에 손상을 가하지 않고 치조골 삭제를 적게 하여 합병증 발생을 줄일 수 있었다. Supernumerary teeth are characterized by an excess number of teeth, which can be responsible for a variety of irregularities in the primary and transitional dentition, Supernumerary teeth, especially in the maxillary anterior region, may prevent the eruption of adjacent permanent teeth and cause their ectopic eruption, diastema, root resorption, or formation of dentigerous cyst. Therefore, early diagnosis of supernumerary teeth is important for prevention of such complications, and adequate treatment should be given according to their location, number, and morphologic features. In this case. four supernumerary teeth in the maxillary anterior region were disturbing the eruption of adjacent permanent incisors. Two of them were located in proximity to the central incisor tooth germs that their immediate removal may injure the permanent tooth germs, In order to minimize such complications, surgical extraction of the four supernumerary teeth was performed in two stages. At first, only two inverted conical supernumerary teeth were extracted. The other two tuberculous supernumerary teeth, close to the permanent tooth germs, were extracted later after their natural dislocation, In that way, we could minimize affects on the neighboring permanent tooth germs and also the amount of alveolar bone removed during surgery.

      • 퍼지 논리 제어기를 이용한 유도 전동기 전류 제어에 대한 연구

        崔洪圭,全光鎬,姜泰垠 홍익대학교 산업기술연구소 1995 産業技術 Vol.5 No.-

        In this paper, we propose the control method of an inverter-fed induction motor using Fuzzy Logic Controller. The FLC chooses the switching states based on a set of fuzzy variables. Error in flux component magnitude of stator current error in torque component magnitude of stator current and flux position are used as fuzzy state variables. Fuzzy rules are determined by observing the vector diagram of flux and currents. The proposed controller shows a good dynamic speed response and decoupling characteristics. Moreover, since the rotor parameter has no effects on the performance the controller and the fuzzy controller possesses highly adaptive capability the performance of fuzzy controller is quite robust and insensitive to the motor parameters and change of operation conditions

      • KCI등재

        차동 기어의 진동 저감을 위한 동력 전달계 진동 해석

        최은오,김희송,안병민,홍동표 한국공작기계학회 1997 한국생산제조학회지 Vol.6 No.3

        Eigenvalue analysis of vibration mode and an analysis by frequency response among the methods of predicting gear noise are related with transmitting sound of vibration. In this study we intended to reduce the vibration noise of differential gear by reducing torque fluctuation of drive pinion shaft which causes vibration noise of differential gear in rear wheel drive vehicles. For this we developed multi-degree of freedom analysis model in which mass moment of inertia and torsional spring combined and we examined the influence of torsional vibration of driveline elements by performing forced vibration analysis of engine excitation torque. We studied the methods for reducing torsional vibration of driveline according to the design factor of propeller shaft and examined the effect reducing vibration in differential gear by flexible coupling.

      • 원자력발전소 증기발생기 수위 제어에 관한 연구

        崔琁雄,姜泰垠,崔洪圭 홍익대학교 산업기술연구소 1996 産業技術 Vol.6 No.-

        About a half of Electric power is generated by nuclear power plants in korea. So, a stable operation of nuclear power plant is very important for suppling the essential national eletric power. A S/G (Steam Generator) level control is the most difficult system in PWR(Pressurized Water Reactor) nuclear power plant. Because of the non-linear and the non-nominal response of S/G level control, it is very difficult to control the level by automatic mode or manual mode. The goal of this study is to establish and verify a advanced control alogorithm by analyzing, modeling, stability calculation, controller parameter calculation, simulation for S/G level control system. The response of a S/G level was analyzed and understood mathmatically by modeling. Some parameters of nuclear power plant were analyzed by modeling and used to simulate the S/G level control. The S/G level control system was tested and analyzed with the S/G level model, the result of the analyzing the control loop is unstable with the present control parameters. The Nyquist mapping method was used to analyze the stability of a control loop. The phase crossover frequency is calculated and applied to verify the stability of a control loop. By calculation of a control parameter which let the phase crossover point be allways in the stability region with the phase crossover frequency, the control loop applied the caulation control parameter is also stable. The S/G level control is more stable and faster by appling the feed-forward control with the calculated control parameter. The result of this study may be applied to analyze and approve the S/G level control system of the nuclear power plants.

      • 폐모세포종 : 1례보고 A Case Report

        최영호,서홍주,임영혁,김정중,박성강,이석기,임진수,김은규 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

        Pulmonary blastoma is a very rare primary neoplasm of the lung. We experienced a case of pulmonary blastoma in a 40 years old man. The mediobasal segmentectomy of the right lower lobe was performed. The patient was discharge on the postoperative days 6. There is no evidence of recurrence or metastasis on followup study during 7 months period after operation.

      • 고속 HMC 이송계의 운동특성 평가 및 운동오차 예측

        최헌종,허남환,강은구,이석우,홍원표 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-

        Recently, the evolution in production techniques (e.g. high-speed milling) and the complex shapes involved in modern production design has been increasingly popular. The key to the achievement is a drastic improvement of the dynamic behavior of the machine tool axes used in production machinery. The more complex these tool paths the higher the speed and acceleration requirements. But it is very difficult to reach the target for high speed machine tool because of the limitations of servo system and motion control system. However the direct drive design of machine tool axes, which is based on linear motors and which recently appeared on the market, is a viable candidate to meet the ever increasing demands, because of these advantages such as no backlash, less friction, more mechanical simplicity and very higher acceleration and velocity comparing to the traditional system. This paper focused on the performance tests of the high speed horizontal machine tool based on linear motor. Especially, dynamic characteristics were investigated through circular test and circular form machining test is carried out considering many important parameter. Therefore these several experiments is used to be evaluated the model for prediction of circular motion error and circular machined error.

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