京畿道 廣州郡 및 富川郡에 있어서의 肺디스토마의 疫學的 調査

尹德鎭,金元撤,全世鍾,李俊鎬,金燉均,尹燾善,南相德 대한의학협회 1965 대한의학협회지 Vol.8 No.9

The level of urinary aflatoxin M1 in Korean adults

Yong-Dae Kim1, Hyojin Kwon, Sun-In Moon, Sang-Yong Eom, Jung-Duk Park, Byung-Sun Choi, Seok-Joon Sohn, Young-Seoub Hong, Ho Kim, Ho-Jang Kwon, Ji-Ae Lim, Hae-Jung Yoon, Gwang-Jin Kim, Heon Kim 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3

Competitive ELISA methods were used to measure the level of aflatoxin M1 (AFM1) from urine in 1008 Korean adults. Subjects were selected by random sampling in all areas of Korea, except Cheju-do. The recovery rate of AFM1 using this method was 105% (73-124%). The geometric mean of urinary AFM1 in all subjects was 3.43 pg/mL (3.67 ng/g creatinine). The level of AFM1 in males was statistically higher, compared with female subjects. However, the levels of AFM1 did not differ according to age. Subjects in Chungbuk-do showed the highest urinary AFM1 concentration, whereas subjects in Kyeongnam-do showed the lowest concentration. Assuming an excretion rate of 5%, this AFM1 excretion corresponds to approximately 0.1 microgram/day in Korean adults.

日本語 會話文에 나타난 敬語使用 分析

김덕준,이정아 경원전문대학 2002 論文集 Vol.24 No.-

We have analyzed the speakers' mental intentions, the situations, the roles of scenes and so on from some viewpoints by the study of verbal expression for respect and politeness by means of the analysis on the colloquial language in Japanese modern novels. The abstract of the analysis result is that the use of honorifics is a means of controlling mental sense of distance besides basic verbal means for paying one's respect to others. Additionally, the honorifics use seems to be generalized as an intention for giving good image of oneself and expressing politeness to others rather than the paying one's respect to them.

最近 十年間 우리나라 主要死因의 變化推移에 關한 硏究

金得祚,尹太永,崔重明,朴淳永,柳東俊 慶熙大學校 1995 論文集 Vol.24 No.-

The authors have made and attempt to examine the transition of the leading causes of death in Korea recently since 1984 by analytically reviewing the annual statistical data on the causes of death for the latest ten years reported mainly from the National Statistical Office and other informative materials. The results were summarized as follows: 1. After the inverting period of the 1970s and early 1980s changing remarkably from the communicable to the non-communicable disease, the leading causes of death were changed to the chronic degenerative diseases such as circulatory disease and malignant neoplasms recently. 2. With the particularly increasing deaths due to the unintentional accidents since the mid-1980s, circulatory disease, malignant neoplasms, and accidents became the three leading causes of death, and accounted for about 66.5 percent of the total deaths in 1993. 3. Concerning the sex-specific leading causes of death, currently they were malignant neoplasms, accidents, cerebrovascular disease, chronic liver disease, and heart disease in males, and cerebrovascuar disease, malignant neoplasms, heart disease, accidents, and hypertensive disease, malignant neoplasms, heart disease, accidents, and hypertensive disease in females in that order respectively. 4. As to the leading causes of death by the age-groups, they were congenital anomaly and infectious disease at infantile age; accidents and unintentional injury at ages 1-39year: malignant neoplasms, circulatory disease, and chronic degenerative disease at ages 40-69years; and circulatory disease, senility and other chronic degenerative disease at ages 70 and over respectively. 5. In reviewing the transition of the leading causes of death, communicable diseases formidably prevailed for the past decades were rapidly decreased recently, and chronic degenerative disease, So-called, "Chronic Illness" such as circulatory disease, malignant neoplasms, and chronic pulmonary disease are in tendency of continuous increase year by year. Although chronic liter disease seems to be stationary in incidence now-a-days, additionally, its level of death is still relatively high. And the death rates due to all kinds of accidents are remarkably increasing. Overall, accidents and unintentional injuries were the third leading cause of death and accounted for about 15 percent of the total deaths.

한국형 우울장애 약물치료 알고리듬 2006 (Ⅲ) : 정신병적 양상을 동반한 주요우울삽화

김원,박원명,서정석,민경준,석정호,전덕인,전현태,이상열,송해철,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : Since the publication of Korean Medication Algorithm Project for Major DepressiveDisorder (KMAP-MD) in 2002, there has been a substantial need for a revision due to rapid progress in the pharmacological management of depressive disorder. We revised KMAP-MD 2002 and developed the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) 2006. Methods : We developed a questionniare for surveying the opinion of experts on pharmacotherapy of depressive disorder. The questionnaire consisted of 4 parts ; 1) treatment of non-psychotic depressive disorder, 2) treatment of psychotic de-pressive disorder, 3) treatment according to clinical subtypes and drugs choice considering adverse effects, and 4) treatment of depressive disorder in women. The questionnaire was completed by the review committee consisting of 101 experienced Korean psychiatrists. It is composed of 22 questions, and each question includes 54 sub-items. We classified the expert opinionto 3 categories (the first-line, the second-line, or the third-line) by χ²-test. Results : For depressive disorder with psychotic features, most reviewers prefer the combination of antidepressant and atypical antipsychotics. Electroconvulsive therapy and the combination of antidepressant and typical antipsychotics were the second-line treatment. Among antidepressants, venlafaxine was the most preferred, and SSRI and mirtazapine followed. Among atypical antipsychotics, quetiapine, risperidone and olanzapine were the most preferred, in this order. In patients who have no response to the first-line treatment, many reviewers recommended switching to another antidepressant or adding another atypical antipsychotics Conclusion : For severe depressive disorder with psychotic features, the combination of antidepressant and atypical antipsy-chotics was preferred for the first-line treatment. These results suggest that the medication strategies of depressive disorder are rapidly changing and reflects the recent studies and clinical experiences.

On-line 학습 신경회로망을 이용한 열간 압연하중 예측

손준식,이덕만,김일수,최숭갑 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

In the face of global competition, the requirements for the continuously increasing productivity, flexibility and quality(dimensional accuracy, mechanical properties and surface properties) have imposed a major change on steel manufacturing industries. Indeed, one of the keys to achieve this goal is the automation of the steel-making process using AI(Artificial Intelligence) techniques. The automation of hot rolling process requires the developments of several mathematical models for simulation and quantitative description of the industrial operations involved. In this paper, a on-line training neural network for both long-term learning and short-term learning was developed in order to improve the prediction of rolling force in hot rolling mill. This analysis shows that the predicted rolling force is very closed to the actual rolling force, and the thickness error of the strip is considerably reduced.

연속냉간압연의 두께제어 모델 개발에 관한 연구

손준식,김일수,권욱현,최승갑,박철재,이덕만 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.5

The quality requirements for thickness accuracy in cold rolling continue to become more stringent, particularly in response to exacting design specification from automotive customers. One of the major impacts from the tighter tolerance level is more unusable product on the head end and tail end of tandem mill coils when the mill is in transition to or from steady state rolling condition. A strip thickness control system for a tandem cold steel rolling mills is composed with blocked non-interacting controller and controllers for strip thickness and tension control of each rolling stands. An intelligent mathematical model included an elastic deformation of strip has been developed and applied to the field in order to predict the rolling force. The simulated results showed that the effect of elastic recovery should be included the model, even if the effect of elastic compression was not important.

全南地域의 人口指標設定 改善方案에 관한 硏究

권준오,김우혁,정영덕 조선대학교 국토개발연구소 1997 국토개발연구 Vol.17 No.1

The aim of this study is to find out appropriate solutions to various problems created by wrong applied assumption of population. And these solutions are to be applied to establishment of urban planning. Besides assuming the population of urban planning is the most important yardstick of deciding the size of future urban and physical environment. Therefore to develop the plan more efficiently, I suggest these as followings. First of all, the mathematical methods which is proper to the characteristics of urban must be applied and produced through the outlook based on analysis of natural population, such as birth, death, transference in the past. Secondly, the moving in population of society must be limited on the target year. Thirdly, the population division plan by regional groups must be proceeded. The last but not least, the examination and evaluation on population plan must be performed.

화학적 폐 손상시 폐 상피세포 장벽의 특성

서덕준,김준연 大韓産業醫學會 1991 대한직업환경의학회지 Vol.3 No.2

The alveolar epithelial barrier permits only restricted passage of solutes, exemplified by a high resistance and equivalent pore properties similar to those of other tight biological barriers. These passive barrier properties may be markedly altered after insults to the lung, perhaps providing insights into the mechanisms of alveolar epithelial injury. The normally tight alveolar epithelium serves as an effective barrier against the leak of solutes from interstitial and vascular spaces into alveolar spaces, thereby helping to maintain the normal "dry" environment required for efficient gas exchange. Until recently, the majority of investigations of alveolar fluid balance relied on intact lung models. The information obtained from these intact mammalian lung studies in vivo and in vitro, if useful, can be difficult to interpret mechanistically, largely because of the anatomical complexity of the lung. For more precise information about alveolar epithelial properties, studies of isolated preparations have been done, providing useful additional approaches to underlying transport machanisms and pathways in the alveolar-capillary wall. In this review article, I introduced the methods being used for study of barrier function in addition to intact lung investigation. And I discussed the barrier properties of the alveolar epithelium relevant to alveolar fluid balance in chemically injured lung, citing the pertinent supporting experimental data where appropriate.

조중 삽화로 입원했던 환자의 재평가 : 혼재성 삽화 진단의 가능성

전덕인,김경란,이 은,손상준 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

Objective : Mixed states are difficult to define precisely and to recognize accurately. Moreover, the DSM-IV criteria for diagnosis of a mixed episode might be too restrictive. The purpose of this study was to investigate the possibility of a mixed episode in bipolar inpatients hospitalized with DSM-IV manic episodes using the Cincinnati criteria, which is a broader criteria compared to DSM-IV. Methods : Inpatient charts of manic patients were carefully evaluated to determine the presence of depressive symptoms in the Cincinnati criteria. The probable mixed patient group was compared with the definitely manic patient group on demographic and clinical variables. The predictability of depressive symptoms for a mixed episode was assessed. Results : Twenty-one out of 101 manic inpatients were possibly diagnosed as mixed episodes. They showed more psychiatric family history, comorbid personality disorder and suicide attempts. Two symptoms (suicidal ideation and helplessness or hopelessness) had good positive predictive value. Conclusion : Diagnosis of a mixed episode can be increased with careful interview and by using a broader diagnostic criteria. The presence of suicidal ideation and helplessness or hopelessness may suggest a mixed state.