저강도 초음파 및 레이저를 이용한 장관골 불유합의 치료

전인호,오창욱,김성중,경희수,박일형,박병철,인주철,여준영 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목 적: 저강도 초음파는 인체 및 동물 실험에서 골조직에 낮은 미세한 물리적 압력을 가하여 골절의 치유에 유리한 영향을 주고, 레이저 (LASER)는 심부 조직에 혈류를 증가시키고, 세포 내 잠재된 에너지를 증가시키는 것으로 알려져 있다. 이에 저자들은 임상적으로 확진된 장관골 붕류합의 치료에 있어 펄스형 저강도 초음파와 레이저를 적용하고 그 효용성을 알아보고자 하였다. 대상 및 방법: 초음파/레이저의 치료 효과를 비교하기 위하여 장관골 불유합으로 확진된 16예 중 8예는 연구군으로 골이식술 후 저강도 초음파와 레이저 치료를 추가하였고 대조군 8예에 대해선 일반적인 골이식술만 시행하여 조사하였다. 남자가 11예, 여자가 5예, 평균 연령은 41.7세 (19~62세)였고, 불유합 부위는 대퇴골이 10예, 경골이 6예였다. 첫 수상으로 인한 골절 후 초음파/레이저 치료까지 시간(골절 연력)은 평균 502일이었다. 결 과: 8예의 연구군에서는 완전 골유합이 6예에서 이루어졌으며 유합까지의 시간은 평균 141일 (101~202일)로 나타난 반면, 8례ㅢ 대조군에서는 5예에서 골유합이 이루어졌고, 유합까지의 시간은 평균 240일 (183~283일)이었다. 결 론: 저강도 초음파/레이져 골절 치료기가 반복된 수술로 인한 난치성 장관골 불유합의 치료에 있어 골이식술과 함께 사용될 경우 긍정적인 효과가 있었고, 특히 최초 가골 형성에 있어 대조군에 비해 그 시간을 줄일 수 있었따. Purpose: Low-intensity, pulsed ultrasound (LIPUS) has demonstrated a stimulation and acceleration of the normal fracture-repair process in cellular bases as well in animal and human models. In this study, the adjunctive effect of LIPUS and LASER was investigated in established nonunion of the long bones. Materials and Methods: Study group consisted of eight patients to whom conventional bone graft and adjunctive LIPUS and LASER was applied. On the other hands, eight patients in the control group underwent bone graft only. Eleven men and five women were included in this study and the average age of the patients was 41.7 years (range, 19~62 years). Six of the tibias and ten of the femurs met the criteria for established nonunion. The average fracture age, the post-fracture period before the start of LIPUS/LASER treatment, was 502 days. Results: Seven of the ten nonunions who were treated by LIPUS and LASER healed completely in an average treatment time of 141 days (range, 101~202 days) and otherwise, in control group, five of the eight nonunions healed completely, in 240 days (range 183~283 days). Conclusion: This clinical study showed a positive effect of LIPUS and LASER on the rate of osseous repair, especially accelerated time to initial callus cortical bridging compared to that of conventional treatment.

역전파 학습 알고리즘의 성능 향상에 관한 연구

전준길,이병호 漢陽大學校 工學技術硏究所 1997 工學技術論文集 Vol.6 No.1

In this paper, we propose a modified error signal to improve the EBP (Error Back-Propagation) algorithm. The output node of network generates a strong error signal in the case that the output node is far from the desired value, and generates a weak error signal in the opposite case. This accelerates the learning speed of EBP algorithm in the initial stage and prevents overspecialization for training patterns in the final stage. The effectiveness of our modification is verified through the simulation of handwritten digit recognition

EMR 남중생의 심폐기능에 관한 연구

전동호,노영태,이상봉,이영덕,박병주,박철준 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of this study is to offer proper physical programs to the middle school EMR boys and to improve their cardiorespiratory function through measuring cardiorespiratory function when they are rest situation, all out situation ten EMR boys, divided into two groups as five exercise boys and five non- exercise ones, played soccer game more than one hour a week for 10 weeks. The results of the measurement by treadmill were as fallows 1. In analyzing the two group t-test score it was found that HR and RQ of both group didn't show statistically significant difference of all(p<0.05). 2. VE, VO₂, Vt, O₂,pluse, CO₂,were revealed the significant difference of rest situation with the exception of all-out situation and recovery(p<0.05) 3. VE, VE/VO₂, O₂/ml/kg. O₂/kg/HR, were revealed the significant difference of all-rest situation with the exception of rest situation and recovery(p<0.05) 4. VO₂, Vt, O₂pluse were revealed the significant difference of recovery situation with the exception of all-out situation and rest(p<0.05) 5. The non-exercise group higher figure in HR, Vt, O₂/ml/kg than exercise group except in VE in the rate of recovery situation in 3 minute

골반내에 발생한 Proximal-type 유상피성 육종 1예

길준철,이상수,전병화,김성훈,손우석,목정은,박양순,강길현 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.4

유상피성 육종은 매우 드문 악성 연조직 육종으로, 전형적인 경우들은 주로 젊은 남성의 수부, 전완부와 같은 신체의 원위부에 피하 혹은 심재성 피부 종괴로 발생하며, 조직학적 소견상 적은 비정형성을 나타내는 유상피성 세포와 방추형 세포의 증식에 의한 다발성 결절 형태의 배열을 보인다. 최근에 전형적인 유상피성 육종과 조직학적 유사성을 가지나 더 공격적인 형태인 proximal-type 유상피성 육종이 보고되었으며, proximal-type은 전형적인 유상피성 육종에 비하여 현저한 유상피성 세포의 발현과 매우 심한 비정형성을 나타내며, 세포가 매우 크고, 소포성 핵과 뚜렷한 핵소체를 보이며, 자주 rhabdoid 세포의 양상을 띈다. 임상적으로는 전형적인 형태에 비하여 호발 연령이 조금 늦고, 주로 체간부에, 특히 골반, 회음부, 생식기 등과 같은 심부에 발생하고, 더욱 공격적인 양상을 나타낸다. 저자들은 13세 소녀에서 원발부위를 알 수 없는, 골반내에 발생한 proximal-type 유상피성 육종 1예를 경험하여, 문헌 고찰과 함께 보고하는 바이다. Epithelioid sarcoma is a rare malignant soft-tissue sarcoma with an unknown histiogenesis, typically presenting as a subcutaneous or deep dermal mass lesion in the distal portions of the extremities of young adults. Recently, a more aggressive, so-called 'proximal-type' epithelioid sarcoma has been reported. In contrast to conventional epithelioid sarcoma, the proximal type is characterized by a predominantly large cell epithelioid cytomorphology, marked cytologic atypia, and frequent occurrence of rhabdoid features in most patients. Proximal-type epithelioid sarcoma has a predilection for appearing in the genitalia, especially the vulva, penis, pelvis and buttocks. Also this lesion appears to be somewhat more aggressive or at least metastasizes earlier than the conventional epithelioid sarcoma. We report a 13-year-old girl who presented with a buge mass filling the pelvic cavity which was painful, hard and fixed on palpation, and was radiologically diagnosed as a malignant germ cell tumors on the CT scan. The mass was surgically excised and pathologically proved to be an proximal-type epithelioid sarcoma of unknown origin.

스포츠·레저용품 구매행동에 관한 연구

박병주,노영태,이상봉,이영덕,전동호,박철준 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The decrease of working time and the increase of leisure time occused by the forms of Factory-Automation, Office-Automation and Household-Automation. The number of people involved in sports & leisure activities are world-widely increasing, and accordingly the demand of sports & leisure goods is outstandingly increased nowdays. In this regard, the main purpose of this study is to find out how the demand and desire of consumers are being formed by purchasing sports & leisure goods, to analysis major influencing consumers' purchasing activities by means of inspecting consumers' recogintion and attitude on sports & leisure goods. The following are results ; 1. In sports & leisure activity, this study is found out that 34 men(15.5%) play once in a week, 31(14.2%) play twice or thrice in a month, 29(13.3%) play twice or three in a week. But 31 women(14.2%) play twice or three in a month, 18(8.2%) play once in a week and 25(11.4%) never do it. 2. In use of purchasing goods, man in that to physical training 114(52.1%), to leisure 13(5.9%), etc 9(4.1%), women buy to leisure 75(34.3%), to physical training 5(2.3%), etc 3(1.3%). 3. The satisfied degrees of consumers is that man(3.82±0.7) is more than woman(2.86±0.7). 4. The determinant factors in purchasing is that woman is higher than, man in price, color, quality and design. But man is higher than woman in brand. 5. In improve method of sports and leisure goods, they answered in quality 113(51.6%), in design 66(30.2%), in price 16(7.3%), in brand 14(6.46%), in color 4(1.8%), etc 6(2.7%). 6. Information resources have mass media 52(23.7%), follow or friends 36(16.4%), show window or seller 21(9.6%). 7. The determinant factors of purchasing goods is 128(58.4%) in quality, 47(21.5%) in design, 37(16.9%) in color, 7(3.2%) in brand.

암 환자의 혈장 Transforming Growth Factor-β1 농도

박병규,하우송,이시은,이수진,박순태,박찬후,전지현,장정순 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCINE 1999 Journal of biomedical laboratory sciences Vol.5 No.2

한국인의 대표적인 성인 고형 종양인 위암, 간암, 유방암과 소아 백혈병 및 2종의 소아 고형 종양 환자로부터 혈장 transforming growth factor-ß1 (TGF-ß1) 농도를 sandwich ELISA 분석법을 이용해 측정함으로써 TGF-ß1을 이 질환들에 대한 새로운 종양표지자 (tumor marker)로 사용할 수 있는지 검토하였다. 또한 연령 및 성별에 따른 혈장 TGF-ß1 농도의 정상치를 조사하였다. 신생아에서 70대까지 혈장 TGF-ß1 농도의 차이는 없었고 남녀간의 차이도 없었다. 위암 환자의 혈장TCF-ß1 농도는 16.0±6.8 ng/ml (평균 ±표준편차)로 정상 대조군의 TGF-ß1 농도 (8.3 ±5.0 ng/ml) 보다 유의하게 높았으나 간암, 유방암 환자의 혈장 TGF-ß1 농도는 대조군과 차이가 없었다. 그리고 위암 환자 16명, 간암 환자 8명, 유방암 환자 7명 중 각각 7명 (43.7%), 1명 (12.5%), 1명 (14.3%)에서만 혈장 TGF-ß1 농도가 증가되었다. 5명의 소아 백혈병 환자에서는 관해 (remission) 여부와 상관없이 혈장 TGF-ßl 농도가 모두 정상 범위에 있었으나 2명의 소아 고형암 환자에서는 종양 절제 전에는 혈장TGF-ß1 농도가 높았다가 절제 후 정상으로 떨어졌다. 결론적으로 1)정상인의 혈장 TGF-ßl 농도는 연령 및 성별에 따른 차이가 없다는 것을 알 수 있었고, 2)성인 고형암인 위암, 간암, 유방암에서는 낮은 민감도로 인해 TGF-ß1을 진단을 위한 선별 검사로 이용하기에는 부적절한 것으로 판단되었으며, 3) 정상 대조군보다 혈장 TGF-ß1 농도가 높았던 위암 환자와 종양 절제 전후로 혈장 TGF-ß1 농도가 민감하게 변했던 소아 고형 암 환자에 대해서는 향후 표본 수를 늘려 부가적인 연구를 해 야 할 것으로 사료된다. To evaluate the usefulness of transforming growth factor-ß1 (TGF-ß1)as a new tumor marker, we determined the plasma TGF-ß1 levels using sandwich ELISA assay in cancer patients. Patients with three most common adult cancers in Korea (stomach, liver and breast cancer) and children's cancers (leukemia and two kinds of solid tumor) were enrolled for the study. Furthermore, 39 individuals were subjected to age and sex-stratified plasma TGF-ß1 analysis. No statistical difference was demonstrated with respect to age or sex. The mean plasma TGF-ß1 level (16.0 ng/ml) of stomach cancer patients was significantly higher than that (8.3ng/ml) of controls. However, there was no difference among the mean plasma TGF-ß1 levels of liver, breast cancer patients and controls. Seven of 16 patients (43.7%) with stomach cancer, one of 8 (12.5%) with liver cancer, and one of 7 (14.3%) with breast cancer showed higher TGF-ß1 levels compared to controls. Plasma TGF-ß1 concentrations of five leukemic children remained in the normal range regardless of the remission state. In contrast, initial high TGF-ß1 levels from two children with solid tumors returned to normal range on surgical resection of tumors. From the above results, we could conclude that plasma TGF-ß1 levels of apparently healthy individuals seem to be rather constant irrespective of difference in age or sex, and the plasma TGF-ß1 has the limited value as a screening test for the diagnosis of aforementioned adult cancers because of its low sensitivity. Finally, additional studies need to be pursed for the large number of stomach cancer and pediatric solid tumor patients in order to reach a secure conclusion on the usefulness of plasma TGF-ß1 as a tumor marker in these patients.

Lesch-Nyhan syndrome 환아의 oral self-mutilation 에 대한 증례보고

최병재,최형준,이제호,전진용 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.1

1. 하순에 심한 self-mutilation wound를 야기한 Lesch-Nyhan Syndrome 환아에서 상하악 유전치에 치관부 절단 및 치수 절세술을 시행하여 치아에 의한 자해를 방지하였다. 2. 장치를 이용한 치료가 어려운 경우 발치가 고려되기도 하나 본 증례에서는 발치보다 보존적인 술식으로 만족할 만한 결과를 얻었다. Self-injurous behavior is defined as deliberate harm to one's own body without suicidal intent. It usually occurs as head banging or hitting, skin cutting, or finger biting and includes ocular, genital and oral self-mutilation. Lesch-Nyhan syndrome is a rate X-linked recessively inherited disorder, caused by complete absence of hypoxanthin-guanine phosphoribosyl transferase(HPRT) activity. Clinical presentation is characterized by mental retardation, chorea, athetosis, hyperuricemia, uricosuria and self-mutilating behavior. In these patients, the most typical feature is loss of tissue from biting themselves, even though they are not insensitive to pain. The dental management of self-mutilation includes treatment with appliances such as soft mouthgrard or lip bumper, extraction of all the teeth, and orthognathic surgery. We report a 25-month-old boy who was a known case of Lesch-Nyhan syndrome and presented with severe self-mutilation wound on his lower lip. Vital pulpectomy and coronal resection was done as a more conservative approach than extracting all primary anterior teeth. Due to maintaining the root portion of the teeth in the bone, it is expected that the normal growth of the alveolar bone will be achieved.

유아특수교육 기관의 개별화교육프로그램 운영실태 및 개선 방안

조광순,전병운,박혜준,홍은숙 국립특수교육원 2005 특수교육연구 Vol.12 No.1

본 연구에서는 유아특수교육교사 8명과의 심층면담과 30개의 IEP 문서 분석을 통해, 특수교육진흥법 상의 규정과 유아특수교육 추천 실제에 따른 IEP의 질적 수준을 알아보았다. 연구결과 특수학급 교사의 경우 유치원 교육과정과의 연계가 부족한 IEP를 작성하여 운영하고 있으며, 개별화교육운영위원회는 실질적으로 소집되지 못하고 있고, IEP의과정에 보호자의 참여 정도는 미미한 것으로 나타났다. 대부분의 IEP 내용은 유아의 현 수행수준에 근거한 장 · 단기 목표의 기술을 제외하고는 상당히 형식적이고 제한적이어서 IEP 운영에 도움을 주지 못하고 있는 것으로 나타났다. 그러나 특수교육진흥법 상에 규정되어 있지는 않지만 실제 현장에서는 가족지원이 다양한 방식으로 이루어지고 있으며, 다학문적 팀의 구성과 구성원들 간의 협력은 교사에 따라, 또는 기관에 따라 큰 차이가 있는 것으로 나타났다. 일반 유치원 프로그램의 일일 계획안과 IEP와의 연계, 발달적 교육과정과 유치원 교육과정과의 연계, 목표의 수정, 개별화교육운영위원회의 협력적 참여, 객관성 있는 수행 평가 면에서 유아특수교육교사들은 어려움을 나타내 보였으며, IEP 작성과 운영에 따른 문제를 해결하기 위해서는 무엇보다도 표준화된 IEP 양식 또는 구조화된 IEP와 평가준거의 예가 제시된 IEP 모델이 필요한 것으로 교사들은 제안하고 있다. Various research has identified a number of problems with individualized education program (IEP) development and implementation among schools, including a lack of adequate teacher training, poorly developed team processes, minimal coordination with general education, and failure to develop measurable goals and objectives to evaluate child achievements. The purpose of this study was to evaluate the quality levels of IEPs implemented in early childhood special education (ECSE) settings based on recommended ECSE practices and requirements of the Korean Special Education Enhancement Act. Through an in-depth focus group interview with eight ECSE teachers from eight different programs and an analysis of 30 IEPs, the study investigated: 1) how regulations on IEP development and implementation of the Special Education Enhancement Act, specifically regulations on IEP team organization and implementation, parent participation, and IEP contents, are interpreted in ECSE programs; 2) how ECSE program professionals collaborate with families and how family supports are provided; 3) how a multidisciplinary approach is put into practice and effective levels of collaboration among IEP team members; 4) ECSE teacher suggestions for solving problems with IEP development and implementation, and for improving practices. The results indicate that special education classroom teachers of regular kindergarten programs develop and implement IEPs that are irrelevant to their curricular. IEP procedural deficits were found in the area of team process. It was found that the ECSE programs lack a multidisciplinary team approach when developing and implementing IEPs. Overall, parental participation was not ensured even though regulations require IEP teams to include parental requests in IEPs and implement their signed IEPs. Key personnel such as regular early childhood education teachers and therapists were found to be absent from IEP meetings. However, differences were found among the programs in the team process. Programs specialized only for young children with disabilities demonstrated higher levels of team approaches than those of ECSE programs in special schools and regular kindergartens. In this study, limited content of IEPs were found to be developed for young children with disabilities. IEP goals and objectives analyzed in this study were shown to be generally adequate, showing that children's levels of performance information and annual goals were congruent and that measurable goals and objectives were developed. During the in-depth interview, it was learned that ECSE teachers provide support to children and families, coordinating services in the community for children with disabilities. The results of this study also show that ECSE teachers in regular kindergarten programs have difficulties in linking IEP goals with their daily instructional plans as well as linking their general curriculum with developmental goals for young children with disabilities. Overall, teachers in this study demonstrated difficulties with modification of IEP goals, facilitating collaborative IEP team participation, and objective monitoring of IEP goals. They suggest that standards for IEP and structured IEP forms be developed. They also suggest that model IEPs be introduced by school districts. The findings of this study suggest that: 1) specific IEP procedures need to be mandated through special education laws and regulations in order to facilitate and monitor team approaches when developing and implementing IEPs in ECSE settings; 2) a coordinated service system is needed to provide comprehensive services to young children with special needs and their families; 3) there is an urgent need for comprehensive curriculum-based assessment tools that reflect various developmental aspects as well as diverse special needs and suggest assessment guidelines; 4) it is important to provide strong pre-service teacher education programs as well as in-service work shops for teachers in order to develope skills in developing meaningful IEP goals and objectives linked to curriculum and daily classroom routines; and 5) IEP model development research should be facilitated.

퇴비 및 액비 시용에 따른 수수×수단그라스와 이탈리안라이그라스 작부체계의 수량과 양분흡수량 및 토양 유효 질소 및 인 변화

임상선,이광승,전병준,이세인 全南大學校 農業科學技術硏究所 2011 農業科學技術硏究 Vol.46 No.-

This study was conducted to investigate productivity and nutrients uptake of Sorghum×Sudan grass (SSG) and Italian ryegrass (IRG) cropping system with cattle manure compost and liquid pig manure application, respectively. Changes in mineral N and available P concentration before and after each cropping were also examined. Dry matter yield ranged from 2.12 to 2.86 ton ha-1 for SSG and from 3.57 to 6.08 ton ha-1 for IRG. Forage productivity observed in this study was substantially lower than other studies probably due both to low precipitation during cropping season and to soil characteristics; lower pH (<5) and available P concentration (ranged from 98.6 to 174.8) than the soils used in the previous studies. The uptake of N and P also showed very similar pattern to dry matter yield; IRG had higher nutrients uptake than SSG. According to nutrient balance analysis, 76.4% of N and 76.9% of P2O5 applied to the fields (161 kg N ha-1 and 265 kg P2O5 ha-1) were not assimilated by SSG. For IRG, 50.2% (133 kg N ha-1) of N applied (265 kg N ha-1) was not taken up; meanwhile, the amount of P2O5 assimilated by IRG was 75 kg P2O5 ha-1, and this was 49 kg P2O5 ha-1 more than that of applied P2O5 (26 kg P2O5 ha-1) as liquid manure, indicating additional P uptake from the soils. Accordingly, mineral N (NH4 + and NO3 -) and available P concentrations of the soils increased after SSG harvest as compared with the soils before cultivation, but they decreased after IRG cultivation. Such differences in nutrient uptake by plant and soil nutrient availability could be attributed to the contrasting availability of nutrients in the compost and liquid manure. Organic forms of nutrients included in the compost is likely to be released slowly by decomposition of organic matter and thus the nutrients released could be utilized by the next crop (IRG) rather than by the crop (SSG) to which compost was applied. On the other hand, as most nutrients in liquid manure is readily available, N and P in the liquid manure could be assimilated by IRG. Therefore, it might be necessary to consider both compost (slowly available) and liquid manure (rapidly available) to achieve a goal production of forage.

여성 스포츠 소비자 증대를 위한 커뮤니케이션 형태 연구

이상봉,노영태,이영덕,전동호,박병주,박철준 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

This study was executed in order to gauge the possibility of the strategy of marketing communication, which was for an increase of female consumer' participation in sports. It was conducted among a random sample of 1.346 women over the age of 18 in Pusan area, and its contents of survey was the shape of leisure activity and preferation of mass media, the aspects of their watching TV. 1. The form of leisure activity seemed to be most favoured as spectators.. Meanwhile sports-type leisure activity appeared to be more favoured by people out of work compared to people in work. 2. It was shown in the most people that they got the media of the use of commercial sports institution by their family or friends. 3. It was shown that female magazines was the most favoured among periodical magazines. 4. In daily newspapers, they prefer local one to central one. Meanwhile sports-newspaper was the worst favoured. 5. TV news was the most preferred, that is in case of the married against the unmarried. 6. It was the most shown that sports program was watched during suitable hours. But a few people answered that they hardly watch that. 7. It was shown that cultural program was watched generally during suitable hours, yet the unmarried scarcely watch that. 8. It was the most shown that comedy program was watched during suitable hours. But a few people answered that they hardly watch that. 9. It was the most shown that dramatic series and movie program were occasionally watched by them.