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      • 船舶優先特權의 被擔保債權에 관한 硏究

        鄭暎錫,李龍鉉,程伊基 한국해양대학교 사회과학연구소 2000 韓國海洋大學校 人文社會科學論叢 Vol.12 No.1

        Maritime lien means a statutory security right with a priority to any other right to vessel and its adjuncts which admits a person having a specific maritime claim to be paid before any other creditors. maritime lien with a priority nat having a public notice may damage to the other creditors. And the ship's arrest for the enforcement of maritime lien may atop the ship's operation. So adjustment of the interest between the person concerned is requested. Maritime lien's recognition was found in the theory of procedural, personification, Conflict, and now in the special circumstances of the maritime corp., limitation of the ship owner's liability, public policy, causam pignoris facere etc. I will suggest some proposals to improve this subject in this paper.

      • Antitumor Activity of Histone Deacetylase Inhibitor Trichostatin A in Osteosarcoma Cells

        Cheng, Dong-Dong,Yang, Qing-Cheng,Zhang, Zhi-Chang,Yang, Cui-Xia,Liu, Yi-Wen Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

        Background: Histone deacetylase (HDAC) inhibitors have been reported to induce cell growth arrest, apoptosis and differentiation of tumor cells. The present study aimed to examine the effects of trichostatin A (TSA), one such inhibitor, on the cell cycle, apoptosis and invasiveness of osteosarcoma cells. Methods: MG-63 cells were treated with TSA at various concentrations. Then, cell growth and apoptosis were determined by 3-(4, 5-dimethyl-2-thiazolyl)-2H-tetrazolium bromide (MTT) and TUNEL assays, respectively; cell cycling was assessed by flow cytometry; invasion assays were performed with the transwell Boyden Chamber system. Results: MTT assays revealed that TSA significantly inhibited the growth of MG-63 cells in a concentration and time dependent manner. TSA treated cells demonstrated morphological changes indicative of apoptosis and TUNEL assays revealed increased apoptosis of MG-63 cells after TSA treatment. Flow cytometry showed that TSA arrested the cell cycle in G1/G2 phase and annexin V positive apoptotic cells increased markedly. In addition, the invasiveness of MG-63 cells was inhibited by TSA in a concentration dependent manner. Conclusion: Our findings demonstrate that TSA inhibits the proliferation, induces apoptosis and inhibits invasiveness of osteosarcoma cells in vitro. HDAC inhibitors may thus have promise to become new therapeutic agents against osteosarcoma.

      • KCI등재

        Acute Hepatitis Due to Agomelatine Use in Elderly Women with Depression: Case Series

        Cheng-Chen Chang,Yen-Jen Chen,Yu-An Chen,Yi-Cheng Liao 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.4

        Although agomelatine may be associated with an increased risk of hepatotoxicity, the incidence rate of acute hepatitis seemed divergent between clinical trials and daily practice. Whether aging or gender is a risk factor in developing hepatotoxicity due to agomelatine is not clear. We present 3 older female cases with acute hepatitis occurring due to highly probable idiosyncratic drug-induced liver injury caused by agomelatine. From these cases, regular surveillance on liver function in the older women taking antidepressants would be of benefits.

      • SSCISCOPUSKCI등재

        Cross-Strait Detente and Implications for U.S. Arms Sales to Taiwan

        ( Cheng Yi Lin ) 한국국방연구원 2013 The Korean Journal of Defense Analysis Vol.25 No.3

        Cross-Strait detente in the wake of China`s rise presents the United States a greater challenge in selling new, advanced weaponry to Taiwan, owing to the political unpredictability of cross-Strait relations and the insurmountable task of maintaining a military balance across the Taiwan Strait. In contrast to the Bush administration, the Obama administration is more concerned about China`s retaliation against U.S. defense corporations involved in arms sales to Taiwan and the maintenance of Sino-American strategic stability. The United States is faced with warming cross-Strait relations and Taiwan`s unknown political destiny with China, complicating faithful implementation of the Taiwan Relations Act (TRA) by the United States. The rise of China has further constrained U.S. policymakers in their deliberation of arms sales to Taiwan. With the signature of 19 cross-Strait functional agreements and all kinds of interflows, Beijing has some evidence-backed arguments that the United States should cease arms sales to Taiwan in accordance with the August17, 1982 Communique. A policy of actively implementing the TRA and providing Taiwan with the most advanced weapons is becoming harder to implement, but the TRA is not moribund unless Beijing renounces the use of force against Taiwan, or Taipei enters a process of political negotiation leading to final settlement of its status with China.

      • KCI등재

        The Accompanying Changes in Brain Structure of a Remitted Depression Patient with the Bupropion Treatment

        Yi-Cheng Hou,Chien-Han Lai 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.3

        The impacts from the bupropion on the brain structures have seldom been mentioned in the literature. The bupropion is a kind of antidepressant with dual action in the norepinephrine and dopamine receptors. Here we have a case to share about the bupropion-related effects in the brain structure.

      • KCI등재

        K-doping effect of the superconductivity in K2xFeTe1-xSx (0.07 ≤ x ≤ 0.3)

        Cheng Cheng,Zhenjie Feng,Qing Li,Tao Li,Qiang Hou,Fei Chen,Zhongmin Ou,Jun-Yi Ge,Shixun Cao,Jincang Zhang 한국물리학회 2019 Current Applied Physics Vol.19 No.4

        Bulk samples of K doping K2xFeTe1-xSx with x=0.07, 0.1, 0.2, 0.3 are successfully prepared by using easy-to-use stable compound K2S as the reactant. The lattice constant calculated from X-ray diffraction patterns indicate that K ions enter the Fe-Te-S layers. K doping is beneficial enhance the superconductivity transition temperature from the R-T curves. The apparent diamagnetic signal is observed in M-T curves when the content of K is smaller than 0.1. However, differential curves (dM/dT) in K-rich samples appear sharp slope mutations, which means that the Meissner effect signal is covered by the increased excess ferromagnetic ions. The number of excess Fe magnetic ions is proportional to K content, which may play an important role in determining the superconductivity.

      • KCI등재

        Bactericidal Activity of Soymilk Fermentation Broth by In Vitro and Animal Models

        Yi-Ping Chin,Ko-Chung Tsui,Mei-Chieh Chen,Cheng-Yi Wang,Chin-Yuh Yang,Yuh-Ling Lin 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.6

        Soybean fermentation broth (SFB) exhibits potent antibacterial activity against different species of bacteria in in vitro assays and animal models. Four isoflavone compounds—daidzin, genistin, genistein, and daidzein—of SFB were analyzed and quantified by high-performance liquid chromatography. In the in vitro test, daidzin and daidzein had more potent antibacterial activity than genistin. The minimum inhibition concentration values for these bacteria of SFB ranged from 1.25%to 5%, and the minimum bactericidal concentration values of strains ranged from 2.5% to 10%, depending on the species or strain. Vancomycin-resistant Entercoccus faecalis (VRE) strains were also tested for susceptibility to SFB in two species of animal model: the Sprague–Dawley rat and the BALB/c mouse. SFB-fed Sprague–Dawley rats showed excellent elimination efficiency against VRE, close to 99% compared with the phosphate-buffered saline–fed control group. In the BALB/c mouse model, SFB antibacterial activity was 65–80% against VRE compared with the control. In conclusion, SFB contains natural antibacterial substances such as daidzin, genistin, and daidzein that inhibit bacterial growth.

      • KCI등재

        Burial depth of anode affected the bacterial community structure of sediment microbial fuel cells

        Yi-cheng Wu,Hong-jie Wu,Hai-yan Fu,Zhineng Dai,Ze-jie Wang 대한환경공학회 2020 Environmental Engineering Research Vol.25 No.6

        Sediment microbial fuel cells (SMFCs) are attractive devices to in situ power environmental monitoring sensors and bioremediate contaminated soils/sediments. Burial depth of the anode was verified to affect the performance of SMFCs. The present research evaluated the differences in microbial community structure of anodic biofilms located at different depth. It was demonstrated that both microbial diversity and community structure of anodic biofilms were influenced by the depth of anode location. Microbial diversity decreased with increased anodic depth. The number of the operational taxonomic units (OTUs) was determined as 1438 at the anode depth of 5 cm, which reduced to 1275 and 1005 at 10 cm and 15 cm, respectively. Cluster analysis revealed that microbial communities of 5 cm and 10 cm were clustered together, separated from the original sediment and 15 cm. Proteobacteria was the predominant phylum in all samples, followed by Bacteroidetes and Firmicutes. Beta- and Gamma-proteobacteria were the most abundant classes. A total of 23 OTUs showed high identity to 16S rRNA gene of exoelectrogens such as Geobacter and Pseudomonas. The present results provided insights into the effects of anode depth on the performance of SMFC from the perspectives of microbial community structure.

      • KCI등재

        Optimal Speed Tracking of Freight Trains Combined with Segmented Soft-Switching Control

        Yi Lingzhi,Yi Yu,Wang Yahui,Xie Cheng 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.1

        Smoothness of travel speed and stopping accuracy are important for freight trains. However, due to the large mass of freight trains, their driving speed is easy to jitter at the operating condition switching point. For these purposes, this paper designs a Dual Mode Optimal Control (DMOC) for tracking the target travel speed of freight trains. This controller contains two sub-controllers, Adaptive Model Predictive Control (AMPC) and Preview control (PC). An Elman Neural Network (ENN) is incorporated in AMPC to adjust the control weights of MPC in real time to output the optimal driving speed. The Afnity propagation-Fast-minimum covariance determinant algorithm, combined in ENN identifes the noisy samples in the training samples and improves the ftting efect of the network. PC and AMPC are fused together by a soft-switching control method. The soft switching control method based on Tanh function can achieve smooth switching of controllers and obtain a good control efect. By comparing with active disturbance rejection control and fuzzy proportional-integral-derivative under two speed profles, DMOC can efectively reduce the speed jitter of speed tracking, improve the stopping accuracy and timeliness of freight trains, and reduce energy consumption.

      • KCI등재

        Late-onset Quetiapine-related Tardive Dyskinesia Side Effects in a Patient with Psychotic Depression

        Yi-Cheng Hou,Chien-Han Lai 대한정신약물학회 2014 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.12 No.2

        The atypical antipsychotics were believed to induce less extrapyramidal syndrome, including tardive dyskinesia (TD). Since theintroduction of the quetiapine, it is also reported with less TD side effects. It even can relieve the symptoms of severe TD andreduce the risk of TD. The quetiapine’s low affinity and fast dissociation from postsynaptic dopamine D2 receptors should givethe least risk of producing the symptoms of TD. The quetiapine even can reduce the TD side effects related to clozapine, whichhas the lowest risk for TD. However, since the first case report of TD side effects related to quetiapine published on 1999,the safety of quetiapine in TD aspect has been questioned. Therefore, we want to share this case report, which was writtento describe the severe late-onset TD side effects after long-term use of quetiapine in a patient with psychotic depression. Thepatient had no significant findings after concurrent comprehensive neurological examinations, magnetic resonance imaging ofbrain and electroencephalogram since the onset of TD.

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