신라검무 및 동일강도의 트레드밀 운동시 심박수, RPE 및 혈중 젖산농도 변화의 비교

오향란,안나영,김기진 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

This study was performed the comparison of physiological function between a sword dance and treadmill running, For the positive factors of sword dance through physical activity and music component on the psycho-hysiological change. Subjects were consisted of 20-aged 16 female sword dancer of 2 groups, as skillful dancer group(n=B) and novice group(n=B), The results were as follow: In graded maximal testing, VO₂max, anaerobic threshold, and recovery capacity after maximal exercise in skillful group showed a higher than novice group. Change of heart rate during a sword dancing is almost similar level to optimal intensity in aerobic exercise program, so sword dance could be suggested an effective exercise program Physiological stimulus to cardiopulmonary function is different response as the different career of sword dance, because novice group showed a significant(p<.05) higher heart rate in sword dance than treadmill running. Blood lactate concentration showed a similar response between sword dancing and treadmill running in both 2 groups. Novice group showed a higher RPE in sword dancing than treadmill running, but skillful group showed a lower RPE in sword dancing than treadmill running. These results mean that the acquainted level of sword dance affected to the psychological response during sword dancing In these result, hypothesis of the similar blood lactate change between sword dancing and treadmill running could be accepted, but RPE is different response as the different career of sword dance.

운동과 적혈구 노화와의 관계

최용어,윤탁영,홍경란 韓國體育大學校附屬 體育科學硏究所 1991 韓國體育大學校附屬 體育科學硏究所論文集 Vol.10 No.1

본 연구는 노화의 정도에 따라 적혈구를 분리하고 장시간의 운동 스트레스가 노화에 미치는 영향을 알아 보고자, 고도로 훈련된 남자 마라톤 선수 3명을 대상으로 HRmax 80% 수준에서 지속적인 런닝을 실시하였다. 전혈에서 RBC, WBC, MCV, Hb, Hct를 측정하고, 적혈구 내에 존재하는 Protein Carboxyl O-Methyltransferase(PCM)을 정제하여 그 activity를 측정하고, 적혈구 막을 분리하여 그 구성 단백질에 대한 PCM 의 Methylatability를 측정하여 운동과 적혈구 노화와의 관계를 설명하고자 한다. 각 시간별, Rest(0분), Running(30, 60, 90, 120분), Recovery(10, 30분)에 혈액을 채혈하여, 전혈에서 RBC, WBC, MCV, Hb, Hct의 변화를 조사하고 (Hematology Analyzer 5), 적혈구를 분리하여 50% Prcoll과 0.154M Hypaque에 넣고 22,000??g에서 40분간 원심분리하면 11 -15개 정도의 적혈구 층이 노화된 정도에 따라 분류된다. 적혈구 세포내의 PCM을 정제하고, 적혈구 막(ghost)을 분리하여 방사성 동위원소 (??C-SAM)를 methyl donor로 하여 PCM activity와 적혈구 막에 대한 Methylatability를 측정하였다. 런닝 30분에 RBC수가 증가하였으며, WBC와 Hb은 운동하는 동안 높은 수준을 유지하였다. MCV와 Hct는 변화가 없었다. Percoll과 Hypaque를 이용하여 노화된 정도에 따라 적혈구를 분류하였으나, 각 층에 대한 세포수의 측정이 뒤따르지 못하여 적혈구 수의 증가 혹은 감소와의 관계를 직접 볼수 없었다. 적혈구 내에서 정제된 PCM activity 는 운동 스트레스에 의한 변화를 보이지 않음으로써 항상 full을 유지하고 있음을 알 수 있다. 적혈구 막에 대한 Methlatability변화는 운동전 26.77±0.32 units/mg.min에서 런닝 30분에 34.29±0.55 units/mg.min로 큰 증가를 보였으며 런닝하는 동안 높은 수준을 유지하였다. 이는 운동 스트레스가 적혈구 막단백질을 구성하는 아미노산에 영향을 미쳐 비정상의 L-isoaspartyl 잔기를 만들었음을 말해주는 것이며, 이것이 노화된 단백질의 수복기전과 일치한다. 즉 PCM이 비정상의 L-isoaspartyl 잔기를 메칠화시켜 정상의 L-aspartyl잔기로 수복시킴으로써 운동 스트레스에 의한 영향을 극복하고자 하는 것이다. 그러므로 장시간의 운동 스트레스가 주는 영향이 노화에 의한 현상과 일치함을 알수 있다. Our studies showed the separation method of erythrocyte according to aging process and the effect that influenced a long-time exercise stress to aging. Highly trained marathon runners (n=3) performed a prolonged running(2hours) at the level of HRmax 80% RBC,WBC,MCV, Hct was measured in a whole blood.Protein Carboxyl O-Methyltransferase(PCM) in the erythrocyte was purified from the cytosol and the activity was measured. Methylatability of erythrocyte membrance protein was measured during marathon performance and recovery phase. Therefore, we interpreted the relation of exercise and erthrocyte aging. The count of RBC increased at the running 30 min. WBC and Hb maintained at the high level during marathon running. MCV and Hct did not changed. Erythrocyte divided into 11-15bands by Percoll and Hypaque according to aging. Because the erythrocyte did not count numerically in different age-related fraction of human erythrocyte, we cannot show the change of erythrocyte count. PCM activity purified in erythrocyte did not change by exercise stress, this suggests that PCM is full at all times. Methylatability of erythrocyte membrane protein changed from 26.77±0.32 units/mg.min before exercise to 34.29±0.55 units/mg.min at 30min after exercise and maintained a high level of methylatability during a running. This suggests that abnormal L-isoaspartyl residues came into being in the membrane protein composition as a result of exercise stress and are repaired by the same mechanism as aging repair that is, PCM methylated abnormal L-isoaspartyl residues in membrane protein and repaired into normal L-aspartyl residues, which removed the effect of exercise stress. Therefore, this study showed that the effect by exercise stress is the same as that of aging process.

마라톤 동호인과 일반인의 체력 및 건강관련 변인의 비교

김혜란 ( Hye Ran Kim ),이만균 ( Man Gyoon Lee ),성순창 ( Soon Chang Sung ) 한국스포츠정책과학원(구 한국스포츠개발원) 2007 체육과학연구 Vol.18 No.4

본 연구는 크게 두 가지의 과제로 구성되어 있다. 제 1과제에서는 중년 남성 마라톤 동호인 45명과 운동습관이 없는 일반인 30명을 대상으로 체격 및 체력수준을 비교하였다. 측정항목은 신장, 체중, 신체질량지수, 체지방률, 1200m달리기, 윗몸일으키기, 팔굽혀펴기, 앉아 윗몸앞으로굽히기, 제자리멀리뛰기, 그리고 50m달리기였다. 제 2과제에서는 중년 남성 마라톤 동호인 15명과 운동습관이 없는 일반인 8명을 대상으로 최대산소섭취량, 젖산역치 수준에서의 산소섭취량, 젖산역치 수준에서의 심박수, 1초 강제 호기량, 그리고 혈액변인을 비교하였다. 두 집단의 데이터를 비교하여 분석한 결과를 요약하면 다음과 같다. 1. 마라톤 동호인과 일반인의 체격을 비교한 결과 체중, 신체질량지수, 가슴 피부두겹 두께, 복부와 대퇴 피부두겹 두께, 그리고 체지방률은 마라톤 동호인이 일반인에 비해 유의하게 낮게 나타났다. 2. 마라톤 동호인과 일반인의 체력을 비교한 결과 윗몸일으키기, 팔굽혀펴기, 앉아윗몸앞으로굽히기, 제자리멀리뛰기, 50m달리기, 그리고 1200m달리기 모두 마라톤 동호인이 일반인에 비해 유의하게 높은 것으로 나타났다. 3. 마라톤 동호인과 일반인의 호흡순환계 변인을 비교한 결과는 최대산소섭취량, 최대심박수, 그리고 VO2LT에서 유의한 차이가 나타났다. 그러나 HR(LT), FEV1.0은 유의한 차이가 나타나지 않았다. 4. 마라톤 동호인과 일반인의 대사관련 변인을 비교한 결과 TG, 그리고 HDL-C는 유의한 차이가 나타났으나, 혈중 글루코스, 인슐린, FFA, TC, 그리고 LDL-C에서는 유의한 차이가 나타나지 않았다. 이상의 결과를 종합해 볼 때, 마라톤 동호인이 일반인에 비해 높은 체력 및 건강수준을 갖고 있는 것으로 나타나 마라톤 동호회 활동이 건강 유지 및 증진, 노화의 지연에 긍정적인 효과가 있을 것으로 판단 되어 진다. 따라서 일반인들이 건강한 삶을 위해 마라톤 동호회의 활동에 적극적으로 참여하기 위한 다양한 방법이 강구되어야 할 것으로 사료된다. The purposes of the study were twofold. The first study was designed to compare physical fitness between 45 marathon club participants(MCP) and 30 general individuals(GI) who have not participated in any systematic exercise training before. Test items in the first study included the standing height, body weight, body mass index, percent body fat, 1200m run/walk, sit-up, push up, sit-and-reach, standing long jump, and 50m dash. The second study was designed to compare maximal oxygen consumption, maximal heart rate, oxygen consumption at lactate threshold(VO2LT), heart rate at lactate threshold(HR(LT)), forced expiratory volume in one second(FEV1.0), and blood variables between 15 MCP and eight GI. All data obtained in the two studies were analyzed by independent-t test and the results were as follows: 1) The body weight, body mass index, chest thickness, abdomen thickness, anterior thigh thickness, and percent body fat of MCP were significantly lower than them of GI. 2) Sit-up, push up, sit-and-reach, standing long jump, 50m dash, and 1200m run/walk of MCP were significantly superior than them of GI. 3) There were significant differenced in maximal oxygen consumption, maximal heart rate, and VO2LT between the two groups. However, there was not significant difference in HR(LT), and FEV1.0 between the two groups. 4) There were significant differences in TG, and HDL-C between the two groups, whereas no significant difference was found in blood glucose, insulin, free fatty acid, TC, and LDL-C between the two groups. The aforementioned results indicated that MCP had higher level of physical fitness than them of GI, concluding that the activities in the marathon club could enhance health and physical fitness and prevent aging. The efforts should put for the general individuals into participate sports club activities.

미국 교육감 선출제도의 특징과 시사점

황아란(Ah-Ran Hwang),박수정(Soo-Jung Park) 한국비교정부학회 2012 한국비교정부학보 Vol.16 No.2

In analyzing the background and features of the US direct election system of the superintendent, this study is intended to present the implications of the US system for the Korean system. This study covers the following: firstly, the background of the US superintendent election system, the progressive era reforms from the late 19th century to the early 20th, and the characteristics of education reforms after 1980s; secondly, concrete contents and cases of the US non-partisan election, which is quite similar to the South Korean system, and the US running-mate system, which is recently considered as an alternative; thirdly, the implications of the US system for the Korean system. This study concludes with the recommendation that like the US current system that the authority of state governors has strengthened in order to enhance consistency and accountability of educational policies, the South Korean superintendent election system should be changed based on educational autonomy’s value and orientation.

청소년의 스트레스 스트레스 대처방식과 위험행동

윤혜미(Hye Mee Yoon),박병금(Byung Kum Park),유정란(Jung Ran Ryu) 충북대학교 생활과학연구소 2005 생활과학연구논총 Vol.9 No.1

  Adolescents" risk behaviors have been studied in may ways. Unique developmental characteristics of adolescence and rapidly changing social environment have drawn attention to explore factors that influence adolescents" risk-taking behaviors. This study examined how stress and stress coping strategies of high school students influence their problem behavior such as internet abuse, smoking, drinking, running-away attempts, and suicidal thinking. Two hundred sixty eight self questionnaires were finally analyzed using SPSSWIN 10.0.   Results showed that adolescents" internet abuse rate(using internet for game and viewing pornography, covert use) was rather high among male adolescents. 23.7% of respondents have experienced smoking, 16.4% current smokers, 85.2% are drinkers with 33.6% binge drinkers, 18.8% have ever actually ran-away, 36.3% have thought about suicide, the data presented Avoidance coping and self-related stress are factors to influence adolescent smoking; family related stress, peer-related stress, and avoidance coping to running away; and elevation of overall stress is a factor to explain suicidal thinking among adolescents.   Limitations of the present study and ideas for the further research are suggested.

Evaluating snow cover changing trends of the Western Indian Himalaya

Seema Ran 대한공간정보학회 2018 Spatial Information Research Vol.26 No.1

The extent of snow cover in the Western Indian Himalaya determines the fluctuations in river discharge during the summer months and affects the water supply for hydroelectric generation, agriculture and related socioeconomic systems which further affect the livelihood of the population in the area and downstream. Despite this importance, there is a lack of information about this region primarily due to the complexities of the processes involved in snow hydrology and the lack of snow cover and depth data in the high elevation areas. Periodical monitoring of the snow cover area (SCA) is an indispensable demand for short-term forecasts of the daily river flows and seasonal forecasts of run-off volume. Therefore, this study is an attempt to assess the annual, seasonal and monthly variations in the extent of snow cover of the Western Indian Himalaya. SCA was estimated using the MODIS/Terra Snow Cover 8-Day L3 Global 500 m (MOD10A2) data for the period 2000–2015. Monthly composite maps of SCA were prepared from 8 days composite snow cover area maps for the Kashmir, Himachal and Kumaon Himalaya. The study found a reduction in snow cover in the Indian Western Himalaya. The inter-seasonal variation in SCA was also observed in the study area. The study found an inter-regional variations in the extent of snow cover in the Western Indian Himalaya during the period of analysis. Emerging changes in the extent of snow cover would influence the availability of water in the near future.

마루운동에서의 앞공중돌기에 대한 운동역학적 분석

김영란,윤희중,이연종 韓國體育大學校附屬 體育科學硏究所 1993 韓國體育大學校附屬 體育科學硏究所論文集 Vol.12 No.1

The Purpose of this study was to describe. the biomecanical factors on forward somersault on floor exercise. Five highly-skilled male collegiate gymnasts were filmed on a high speed video camera form the start to the landing. Also experimental set-up consisted of a force plateform interfaced to a laboratory computer. The results of this study could be summarized as follows. l. It showed that vertical ground reaction force patterns, including only single peak point, indicated that the subjects did not contact the force platform with heel of both feet but rather contacted on the mid hall of feet. 2. It showed that anteroposterior ground reaction force were charecterized a braking force posteriorly directed during the most of support phase and a propelling force anteriorly directed the last short period of support phase. 3. It showed that the wave forms of the mediolateral ground reaction force curve indicated a little changes. 4. It Showed that the support time of both feet on the force platform took 0.127 sec, but lack the velocity transfer ability from horizontal velocity at run-up to vertical velocity at take-off.

이미지 색상, 명도, 채도 감성컴퓨팅의 유사성 검증 연구

이연란(Lee, Yean-Ran) 한국만화애니메이션학회 2015 만화애니메이션연구 Vol.- No.40

사람의 이미지 감성인식은 각기 다른 성향으로 표현된다. 현재는 감성인식을 객관적으로 평가하려는 감성컴퓨팅 연구가 활발하게 연구되고 있다. 그렇지만 기존의 감성컴퓨팅 연구는 실행에 많은 문제점을 갖고 있다. 첫째, 감성인식 면에서 비객관적이고, 부정확하다. 둘째, 감성인식의 상관관계가 불명확한 점이다. 그리하여 본 연구의 필요성으로 이미지 감성의 규칙성을 실험하여 감성컴퓨팅 방식으로 제어하고자 한다. 또한 본 연구의 목적으로 감성인식을 숫자화하고, 객관화하는 이미지 감성컴퓨팅 시스템 방식을 적용하고, 사람의 감성과의 유사 정도를 비교한다. 이미지 감성컴퓨팅 시스템의 주요 특징은 감성인식을 숫자화 된 디지털 형식으로 계산한다. 그리고 감성컴퓨팅의 연구배경은 감성을 디지털화하는 James A. Russell의 핵심 효과(Core Affect)를 활용한다. 핵심 감성으로 쾌정도(X축)인 쾌와 불쾌, 긴장도(Y축)인 긴장과 이완의 감성축이고, 감성컴퓨팅 연구에 적용한다. 감성축은 연관된 대표감성으로 아주 기쁜, 흥분, 의기양양, 행복한, 자족, 고요한, 여유로운, 조용한, 피곤한, 무기력한, 우울한, 슬픈, 화가 난, 스트레스, 불안, 긴장된 감성의 16개로 구분하여 감성컴퓨팅에 적용한다. 본 연구의 과정은 이미지 감성컴퓨팅 계산식의 핵심인 색채 요소를 활용하여 색상, 명도, 채도를 감성속성요소로 적용한다. 감성속성요소는 중요도인 가중치를 적용하여 비율을 계산하고, 쾌정도(X축)와 긴장도(Y축)의 감성점수로 측정한다. 다시 교차된 감성점을 바탕으로 감성원으로 확장하고, 포함된 대표감성크기로 상위 5위인 주요대표감성으로 선별한다. 또한 사람의 이미지 감성을 16개 대표감성점수로 측정하고, 상위 5위의 대표감성으로 구분한다. 연구결과 감성컴퓨팅의 주요대표감성과 사람의 감성인식의 주요대표 감성을 비교하여 일치하는 대표감성수에 따라 감성의 유사 정도를 검증한다. 감성컴퓨팅 유사성 실험 결과 주요대표감성의 평균 일치율은 51%이고, 2.5개의 대표감성이 사람의 감성인식과 일치했다. 본 연구를 통해 감성컴퓨팅 계산 방식과 사람 감성인식의 유사 정도를 측정했고, 감성계산식의 객관적인 평가기준을 제시했다. 향후 연구에서는 좀 더 높은 일치율 향상의 방안과 감성계산식의 가중치 연구가 유지되어야 할 것이다. Emotional awareness is the image of a person is represented by different tendencies. Currently, the emotion computing to objectively evaluate the emotion recognition research is being actively studied. However, existing emotional computing research has many problems to run. First, the non-objective in emotion recognition if it is inaccurate. Second, the correlation between the emotion recognition is unclear points. So to test the regularity of image sensitivity to the need of the present study is to control emotions in the computing system. In addition, the screen number of the emotion recognized for the purpose of this study, applying the method of objective image emotional computing system and compared with a similar degree of emotion of the person. The key features of the image emotional computing system calculates the emotion recognized as numbered digital form. And to study the background of emotion computing is a key advantage of the effect of the James A. Russell for digitization of emotion (Core Affect). Pleasure emotions about the core axis (X axis) of pleasure and displeasure, tension (Y-axis) axis of tension and relaxation of emotion, emotion is applied to the computing research. Emotional axis with associated representative sensibility very happy, excited, elated, happy, contentment, calm, relaxing, quiet, tired, helpless, depressed, sad, angry, stress, anxiety, pieces 16 of tense emotional separated by a sensibility ComputingIt applies. Course of the present study is to use the color of the color key elements of the image computing formula sensitivity, brightness, and saturation applied to the sensitivity property elements. Property and calculating the rate sensitivity factors are applied to the importance weight, measured by free-level sensitivity score (X-axis) and the tension (Y-axis). Emotion won again expanded on the basis of emotion crossed point, and included a representative selection in Sensibility size of the top five ranking representative of the main emotion. In addition, measuring the emotional image of a person with 16 representative emotional score, and separated by a representative of the top five senses. Compare the main representative of the main representatives of Emotion and Sensibility people aware of the sensitivity of the results to verify the similarity degree computing emotion emotional emotions depending on the number of representative matches. The emotional similarity computing results represent the average concordance rate of major sensitivity was 51%, representing 2.5 sensibilities were consistent with the person"s emotion recognition. Similar measures were the degree of emotion computing calculation and emotion recognition in this study who were given the objective criteria of the sensitivity calculation. Future research will need to be maintained weight room and the study of the emotional equation of a higher concordance rate improved.

Serious adverse events during clinical trial for pharmacokinetic interation between telmisartan and chlorthalidone in healthy Korean subjects: A case report

( Sook Jin Seong ),( Young Ran Yoon ),( Mi Sun Lim ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-

Te1misartan is an angiotensin II receptor antagonist and chlorthalidone is a thiazide-like diuret-ics. In this study, we report serious adverse events (SAEs) during clinical trial for pharmacokinetic interaction between telmisartan and chlorthalidone in healthy Korean subjects. Two separate, ran-domized, multiple-dose, two-period, one-sequence studies were conducted at Kyungpook National University Hospital. In part A, 43 volunteers received telmisartan for 7 days, and then chlorthali-done for 14 days (days 8-21). Telrnisartan was co-administered during day 15-21 to evaluate the effects of chlorthalidone on the pharmacokinetics of telmisartan at steady state. A healthy 36-year-old male in part A was referred to the emergency room due to severe nausea and vomiting developed about 3 h after administration of chlorthalidone on day 9. Hypokalemia and QT prolongation were observed during his initial laboratory examination and electrocardiogram (ECG) monitoring in the emergency wilt. Nausea and vomiting improved after conservative management with hos-pitalization for 9 days. We consider that the episodes of excessive nausea and vomiting resulted in hypokalemic state which was potentiated by chlorthalidone. And the hypokalemic state caused the lengthening of the QT interval on ECG.

초고성능액체크로마토그래피-텐덤질량분석법에 의한 혈청 중스핑고신과 스핑고신-1-포스페이트의 동시 분석

나승훈(Seonghoon Na),윤혜란(Hye-Ran Yoon) 대한약학회 2021 약학회지 Vol.65 No.1

Sphingosine (SPH) and sphingosine-1-phosphate (S1P) are emerging as key players in asthma metabolism and in numerous cellular inflammation processes. To identify potential biomarkers of asthma and inflammatory therapeutics, it is essential to determine their levels. Herein, we developed a rapid and sensitive UHPLC-MS/MS method to simultaneously quantify SPH and S1P in human serum using C17-SPH and C17-S1P as internal standards. After methanol precipitation of serum proteins, the supernatants were analyzed by MS/MS performed in the positive ion mode by multiple reaction monitoring. UHPLC analysis (C18 column) was performed using two mobile phase systems (water containing 0.1% formic acid, and 85% acetonitrile containing 0.1% formic acid) within 5 min of the short run. The calibration curves were linear in the range of 0.002-1.5 µg/mL for S1P and SPH with an R 2 greater than 0.9999. The LOD and LOQ were 0.0002 and 0.0004 µg/mL for S1P, and 0.0005 and 0.001 µg/mL for SPH, respectively. The accuracy and precision of the method were in the range of 89.8-100.7% (RSD, 1.5-2.8%) for both SPH and S1P species. We were able to quantify both molecules in serum from healthy and asthmatic patients. These results suggest that SPH and S1P are promising potential biomarkers, and also contribute to the basic data for the construction of an omics-based platform for preventive index prior to asthma diagnosis.