The Ameliorative Effects of Korean Bean‐Leaves on Inflammation and Liver Injury in Obese Rat Model

Byung?Moon Jin,Seok?Cheol Choi,Hye?Sook Lee,Sang?Bong Jung,Kyung?Yae Hyun 대한의생명과학회 2013 Biomedical Science Letters Vol.19 No.3

Obesity may cause metabolic syndrome and adult diseases. This study was undertaken to investigate the ameliorative or useful effects of beanleaves on inflammation and liver damage in obese rat models. Rats were divided into three groups: a control group (normal diet, n=6), a fat diet group (45%?fat diet, n=7), and a bean leaf group (45%?fat+Korean bean leaves diet, n=7). Body weights in the bean leaf group were lower than those of the fat group (P<0.05). Serum tumor necrosis factor?α (TNF?α) and prostaglandin E₂ (PGE₂) concentrations were lower in both the control and bean leaf groups than in the fat group (P<0.001). TNF?α concentrations in the bean leaf group were slightly higher than in the control group but statistically significant (P<0.05). The bean leaf group histologically exhibited lower fatty degeneration, spotty necrosis, and leukocyte infiltrations in hepatic tissues than those of the fat group. In the homogenized liver tissues, the cyclooxygenase?2 (COX?2) gene was only expressed in the fat group. The gene expression levels of hepatic TNF?α, inducible nitric?oxide synthase, peroxiome proliferator?activated receptor?α (PPAR?α), poly (ADP?ribose) polymerase (PARP), and transforming growth factor?β1 (TGF?β1) were weaker in the bean leaf group than in the fat group. These results suggest that adding bean?leaves to the diet may ameliorate obesity?induced systemic inflammation and liver damage and that bean leaves may be a useful food for preventing obesity and thereby metabolic syndrome and adult diseases

신체계측 및 검사소견을 중심으로 한 四象人의 특징에 대한 분석

李壽瓊,高炳熙,宋一炳 경희대학교 1996 慶熙醫學 Vol.12 No.3-4

초등학생의 창의성 발달 경향 분석

이경화(Lee, Kyung hwa),최병연(Choi, Byung yeon) 한국영재교육학회 2012 영재와 영재교육 Vol.11 No.2

본 연구의 목적은 우리나라 초등학생의 창의성 발달 경향을 분석하는데 있다. 창의성에 대한 기존 연구를 종합하여 창의성을 창의적 능력과 창의적 성격 영역으로 구분하고, 각 영역의 하위 요인들을 분석하고자 하였다. 이를 위하여 전국 시도별로 편의 표집을 통해 초등학생(1-6년) 2,248명의 창의성을 측정하고 학년별 차이를 분석하였다. 그 결과 창의적 능력 및 하위 요인(유창성, 융통성, 독창성, 상상력, 사고의 민감성, 정교성) 점수는 학년이 올라갈수록 높아지는 것으로 나타났지만 하위 요인에 따라 다른 발달 양상을 보였다. 반면, 창의적 성격 및 하위 요인(호기심, 민감성, 과제집착력, 유머, 독립/모험성, 문제해결 리더십) 점수는 학년이 올라갈수록 낮아지는 것으로 나타났으며, 요인에 따라 다른 발달 경향을 보이는 것으로 밝혔다. 마지막으로 창의적 능력과 창의적 성격 점수를 합한 창의성은 학년 간에 통계적으로 유의한 차이는 없었지만, 2학년 때 낮아지다가 상승한 다음, 다시 5학년 때 낮아졌다가 6학년 때 상 승하는 W자 형태의 발달 경향을 보이는 것으로 밝혀졌다. 본 연구의 결과는 창의·인성교육에 기초한 초등학생들의 창의성 발달 경향에 관한 연구는 물론 초등학교 각 학년 특성에 적합한 창의성 교육 프로그램을 개발하는데 기여할 것이다. This study analyzed the developmental characteristics for creative ability and creative personality of elementary school students. The Korean Individual Creativity Test, developed by Kyung-Hwa Lee, was used to measure creativity. This test consists of two domains, creative abilities (flexibility, fluency, originality, elaboration, sensitivity to thinking) and creative personalities (curiosity, sensitivity, task commitment, humor, challenge, leadership of problem solving). Approximately 2,248 participants were selected all over the Korea. Developmental trends by grades was analyzed. This study demonstrated that the scores of creative thinking ability increased from the first grade to the sixth grade. There was no fourth grade slump as proposed by Torrance (1968). Rather, this result supported the increment view in creative thinking with age. Older children are supposed to be higher in creativity as their social experience and education training become broader. However, the scores of creative personality decreased from the first grade the sixth grade steadily in this study. As children get into higher grades, they are more likely to compare and evaluate with their peers. Also, they are under more peer pressure to confirm. These negative climates block the creative personality of the older students.

초등학생의 발달단계에 따른 창의적 능력과 창의적 성격 및 영역 창의성 분석

이경화(Lee Kyung hwa),최병연(Choi Byung yeon) 한국영재교육학회 2006 영재와 영재교육 Vol.5 No.2

본 연구는 우리나라 초등학생의 창의성, 즉 창의적 능력과 창의적 성격의 관계 및 발달단계에 따른 차이를 분석함으로써 초등학생들의 창의성의 발달적 특성을 이해하여 창의성 계발을 위한 교육에 시사점을 제공하고자 하는데 목적이 있다. 이를 위하여 개별창의성검사를 사용하여, 1학년부터 6학년까지 초등학생 825명의 창의성을 측정하고 그 결과를 분석하였다. 그 결과 독창성을 제외하고 모든 창의성의 요인들이 학년과 상관관계가 있음을 알 수 있었다. 창의적 능력은 하위 요인 중 독창성과 가장 높은 상관이 있는 것으로 나타났으며, 창의적 성격은 하위 요인 중 민감성과 높은 상관이 있는 것으로 나타났다. 창의적 능력과 창의적 성격을 학년에 따라 분석한 결과, 초등학생들의 창의성 발달은 비연속적인 특성을 나타낸다는 것이 확인되었다. 반면에 초등학생들의 창의적 성격은 학년이 증가함에 따라 점점 더 발달해 가는 것으로 나타났다. 한편 영역 창의성의 발달 단계별 차이를 확인한 결과, 언어와 조작 창의성은 학년의 증가에 따라 높은 반면에, 도형 창의성은 3학년 까지 상승하다가 4학년 때 하강하여 다시 상승하는 것으로 나타났다. This study analyzes the developmental characteristics for creative ability, creative personality and domain creativity of Korean elementary school children. The Korean Individual Creativity Test (KICT), developed by Kyung-Hwa Lee, was used to measure creativity. KICT consists of three domains, three creative abilities and three types of creative personalities. The three domains involve language, drawing, and manual operation. The three creative abilities involve fluency, flexibility and originality. The three personality types involve curiosity, sensitivity, and task commitment Approximately 825 participants were selected in the 18 regions of Korea according to the ratio of schools. The results of this study was that creative abilities had high correlation with originality factor and creative personalities had high correlation with sensitivity factor. Also, primary school children"s creative abilities peaked at grade 3 and fell down sharply at grade 4. Whereas, children"s creative personalities developed as the children"s grade increased. Finally, language and manual operation increased with children"s grade, but drawing operation showed same trend as that of creative abilities. These results imply that, when we assess the creativity development of primary school children, we would do well to analyze their developmental creativity characteristics in terms of the implications for the future development of creative teaching and learning programs.

대학 무용수의 자기관리가 무용자신감과 공연수행만족에 미치는 영향

오경록(Oh, Kyung-Rok),전병관(Chun, Byung-Kwyan) 한국체육과학회 2015 한국체육과학회지 Vol.24 No.6

The purpose of this study was to identify the influence of self management of university students majoring in dance. Using a purposive sampling method, the survey was conducted to 280 of university students majoring dance in Seoul and Kyung-gi Province. The collected data was statistically processed by exploratory factor analysis, Cronbach"s test, frequency analysis, correlation α analysis and multiple regression analysis using SPSS 21.0. The results of the analysis can be summarized as the following. First, the self management of University students majoring dance influenced on dance confidence significantly. Second, the self management of University students majoring dance influenced on dance performance satisfaction significantly. third, The dance confidence of University students majoring dance influenced on dance performance satisfaction significantly. These findings can be referred as practical data for dancers and coaches in fields of dance to improve the dance performance satisfaction.

A Study on the appropriate herbal medicine according to Sasang constitution using EAV

Choi,Jin-Wook,Lee,Su-kyung,Hong,Suck-chull,Koh,Byung-hee INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1997 JOURNAL OF ORIENTAL MEDICINE Vol.2 No.1

1. Objective This is a basic study about the response of herbal medicine to EAV. The purpose was to investigate how the meridian of EAV responded to herbal medicine and how EAV was applied to the diagnosis of Sasang constitution. 2. Materials & Methods The subjects of this study were patients who were being treated in the Dept. of Constitutional Medicine ot Kyung-Hee Medical Center. The study examined how herbal medicine affected the maximum value and the indicator drop and how each constitution responded differently to the constitutional herb medicine. 3. Results & Conclusions 1) When comparing the maximum value and ID of the worst BAP before and after the experiment with herbal medicine, the maximum value significantly went up and the ID significantly went down in all the herbal medicines. So we confirmed that all the herbal medicines positively affected the change of the maximum value and ID. 2) The changes in the maximum value induced by herbal medicines were significantly different according to the constitution of Dokhual Jihwang Tang, and Hyangbuja Palmul Tang. Although Dokhual Jihwang Tang was soyangin's herb medicine in Sasang constitutional medicine, it raised the value of soeumin higher than that of soyangin. Hyangbuja Palmul Tang which was soeumin's herb medicine raised the value of soeumin higher than that of the other constitution. 3) The changes of ID were not significantly different in the constitution.

식사대용 식품(Ready-to-eat meals) 중 병원성 세균의 분포와 항생제 감수성 양상

홍은경,김윤아,이도경,강병용,하남주,Hong, Eun-Kyung,Kim, Yun-A,Lee, Do-Kyung,Kang, Byung-Yong,Ha, Nam-Joo 한국미생물학회 2006 미생물학회지 Vol.42 No.4

본 연구에서는 2005년 11월부터 2006년 3월 초까지 497개의 초밥, 김밥, 샌드위치 등의 식사대용 식품 검체를 수거하여 식품공전을 토대로 식사대용 식품에서 유래되는 미생물학적 인 오염도를 조사하고, 현대 사회에서 항생제 사용의 오남용으로 항생제 내성이 심각한 상황을고려하여 분리된 균에 대한 항생제 감수성 양상에 대하여 알아보고자 하였다. 수거된 검체를 실험한 결과 김밥에서 4개(1.4%)의 Escherichia coli가 분리되었고, 초밥, 샌드위치 등에서는 분리되지 앓았다. 또한 김밥에서 12개(4.4%), 초밥에서 8개(5.4%), 샌드위치에서 2개(4.3%)로 총22개(4.4%)의 Staphylococcus aureus가 분리되었다. 식사대용 식품에서 분리된 26개의 균주로 National Committee for Clinical Laboratory Standards (NCCLS)의 기준에 의거하여 vancomycin, teicoplanin, gentamycin, cipro-floxacin, synercid, cefotaxime, lincomycin, meropenem, cefazolin, amoxicillin-clavulanic acid으로 총 10개의 항생제를 사용하여 E. coli와 S. aureus의 항생제 감수성 양상을 파악해 보고자 하였다. 실험 결과 식사대용 식품에서 분리된 E. coli 4균주의 항생제 감수성 양상은 그람 음성균 치료에 주로 사용되는 항생제인 gentamycin, ciprofloxacin, cefotaxine, meropenem, cefazolin에 대해서는 감수성이 높다고 판단되었으나 amoxicillin-clavulanic acid에 대해서는 내성을 나타내었고, S. aureus의 항생제 감수성은 비교적 높다고 판단되었다. This study was performed in order to measure the level of food-borne pathogenic bacteria and antibiotic resistance pattern of found ready to eat meals such as Him-bap, Cho-bap, Hamburger, Sandwich and packed lunch boxes. A total of 497 samples were collected from supermarket and department of Seoul, Kyung-ki, Inctleon, Kang-won, Chung-Cheong from November, 2005 to March, 2006. The contaminated microorganisms were in most cases tract relative strain like E. coli and S. aureus. Result have shown E. coli was detected 4 strains and S. aureus was detected 22 strains. 26 strains were also tested the antibiotic resistance pattern. 26 strains were shown to be relatively susceptible to synercid, vancomycin, teicoplanin, ciprofloxacin, gentamycin, lincomycn, cefotaxime, meropenem, cephalosporin, amoxicillin-clavulanic acid by the MIC dilution method, but E. coli 1 strain was resistant to amoxicillin-clavulanic acid.

태음인 중풍환자에 있어 체질치료가 체중감소에 미치는 영향에 대한 임상적 연구

박계수,이수경,고병희,송일병,Park, Gye-soo,Lee, Su-Kyung,Koh, Byung-hee,Song, Il-byung 사상체질의학회 2001 사상체질의학회지 Vol.13 No.1

The Clinical Study on the Body Weight Loss of Taeumin Inpatients in Stroke by Sasang Constitutional Medicinal Treatment. Purpose: It has been frequently noted that overweight and obesity have a stronger relationship to hypertension and diabetes mellitus than to the risk of stroke. The purpose of this study is to find out whether Sasang Constitutional Medicinal treatment in the stroke patients of Tae-um-in has an effect on local or general weight loss. Methods: Case-control study was applied. The experiment group is the 24 Taeumin stroke inpatients who were in hospital in Kyung-Hee Oriental Hospital from July 1, 2000 to October 1 and received Sasang Constitutional Medicinal treatment. The control group is the 13 Taeumin stroke inpatients who were in the hospital during the same period but didn't receive Sasang Constitutional Medicinal treatment. In the two groups, body weight, BMI, the skin fold(cm) of triceps, suprailiac, abdominal portion, and thigh and the circumference(cm) of wrist, biceps, triceps, and W/H ratio were compared and studied for three weeks. Results: 1. In the experiment group, there were 8 women and 15 men, 23 in total and in the control group, there were 5 women and 9 men, 14 in total. 2. From two weeks later, there was a significant decrease in the experiment group in weight loss, the ratio of loss, and BMI(p<0.05). 3. Concerned with the change in the skin fold of suprailiac portion, there was a significant decrease in each group(p<0.05). 4. Concerned with the change in the skin fold of Chunchu-Hyel portion(天樞穴), thigh and in the circumference of hip, W/H ratio, there was a significant decrease in the experiment group(p<0.05). 5. Concerned with the change in the value of Lipid Profile, GOT, and GPT, only Glucose(GLU) showed a significant decrease(p<0.05) in the experiment group(p<0.05). As Conclusion, Sasang Constitutional Medicinal treatment in the stroke patients of Tae-um-in has an effect on local or general weight loss.

한열변증에 따른 중풍 환자의 제반특성 비교

김민경,이인환,신애숙,김나희,김혜미,심소라,나병조,조승연,박성욱,정우상,문상관,박정미,고창남,조기호,김영석,배형섭,Kim, Min-kyung,Lee, ln-whan,Shin, Ae-sook,Kim, Na-hee,Kim, Hye-mi,Shim, So-ra,Na, Byung-Jo,Cho, Seung-yeon,Park, Seong-uk,Jung, Woo Sang 대한중풍순환신경학회 2010 대한중풍.순환신경학회지 Vol.11 No.1

Object : This study was conducted as part of the national project to standardize stroke diagnosis in Korean medicine. In this study, we aimed to evaluate the characteristics of acute stroke between heat pattern group and cold pattern group. Methods : We recruited stroke patients from 5 universities(Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo medical center, Kyungwon university lncheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university llsan oriental medical center) from April, 2007 until February, 2010. We diagnosed them and selected 463 heat pattern patients and 182 cold pattern patients. Results : We find that the risk factor of smoking, alcohol, diet(prefer to meat) are more associated with the heat pattern group. On the other hand, inflammation history in recent 3 months and diet(prefer to sea food) are more associated with the cold pattern group. RBC, Hg, Hct, TG, CK and Cl are more related to the heat pattern group. CPT, total cholesterol and HDL are more related to the cold pattern group. Tae-eum type takes high distribution of the heat pattern group, and So-eum type takes high distribution of the cold pattern group. Conclusions : This study provides evidence that the heat pattern group have more risk factor than the cold pattern group.

부신백질이영양증(Adrenoleukodystrophy:ALD)을 진단받은 태음인(太陰人) 환자의 치험 1례

임진희,황민우,함통일,이수경,고병희,송일병,Lim, Jinny,Hwang, Min-Woo,Ham, Tong-Il,Lee, Soo-Kyung,Koh, Byung-Hee,Song, Il-Byung 사상체질의학회 2004 사상체질의학회지 Vol.16 No.1

Purpose The primary purpose of this case study is to report that a Taeumin patient diagnosed to Adrenoleukodystrophy was managed with Taeumin constitutional treatment. Subject A male patient diagnosed to Adrenoleukodystrophy that was treated Kyung-Hee Oriental Medicine. Result A Taeumin patients diagnosed to Adrenoleukodystrophy was treated with a herb-medicine and acupuncture treatment, and change of his subjective symptom & general condition was managed. Conclusion The consitutional treatment with herb-medicine and acupuncture may have an effect on Management of Adrenoleukodystrophy. Further study on management of this disease is needed.