부산지역 수돗물과 지하수의 중금속 농도

김준연,손지언,김형수,김두희,원미숙,김인식,이혜령 동아대학교 산업의학연구소 2000 산업의학연구소 논총 Vol.- No.5

This study investigated mean airborne CO concention of 15 workplaces, suspected of CO exposure and conducted self-reported questionnaire completion and indirect COHb concentration measure using Micro II Smokerlyzer to healthy 702 adult subjects from 1999 May to 1999 September in order to find a relation of CO exposure and occupational factors, socioeconomic factors, and health related behaviors and confirm the related conditions in the screening test for CO exposure. The results of this study were summarized as follows : 1. In the CO exposed and non exposed group, COHb concentrations of the smokers were 2.55±0.96% and 2.21±0.97% and that got a statistically significant difference, There were not statistically significant differences in the age and total smoking index. Passed times after the last smoking, Working time/day, and working duration were statistically significant difference (p〈0.05). 2. In the CO exposed and non exposed group, COHb concentrations of non-smoking group were 0.94±0.35% and 0.68±0.47% and that got a statistically significant difference. There were not statistically significant differences in the age and working duration but Working time/day was a statistically significant difference(p〈0.05). 3. In the CO exposed group, r-square of multiple regression of the smokers was 38.5 % and passed time after the last smoking, working time/day, and job category were statistically significant differences (p〈0.05). And r-square in the CO non-exposed group was 38.3 % and age, passed time after the last smoking, and total smoking index were statistically significant difference. 4. In the CO exposed group, r-square of multiple repression of the non-smokers was 66.3% and job category and airborne CO concentration were statistically significant differences(p〈0.05). But r-square of non-smokers in the CO non-exposed group was 1.0% and there was not a statistically significant difference(p〈0.05). 5. In the smokers of CO exposed and non exposed groups, relation of COHb concentration and passed time after the last smoking was expressed as exponential function, Y = 2.9182e-0.0083x and r-square of this function was 37.4%. Therefore it was more than 150 minutes that passed time after the last smoking was when COHb concentrations were measured as less than 1%. In conclusion, variable, that was statistically significant to COHb concentraion in the both CO exposed and non-exposed smokers, was a passed time after the last smoking. We suggest that you have to restrict the smoking of smokers at least 150 minutes in the exposed and non exposed group before COHb concentration measure in order to exclude smoking effects

鼻알레르기의 호산구내 효소에 관한 전자현미경적 연구

吳世明,鄭泰仁,金基鈴 대한이비인후과학회 1977 대한이비인후과학회지 두경부외과학 Vol.20 No.3

청소년의 자아존중감과 정신건강에 관한 연구

최은영,최인령 韓國學校保健學會 2002 韓國學校保健學會誌 Vol.15 No.1

The purpose of this study was to find out the relationship between self-esteem and mental health in Middle school students, and provided basic data to develop a nursing program for the prevention of mental disease and the promotion of mental health in adolescence. Subjects were 153 students in the third year of three middle schools located in K city. Instruments used in this study were the self-esteem questionnaire developed by Choi, B. K. & jun, G. Y.(1993) and the simplified SCL-90 developed by Lee, H. K.(1986) for measuring mental health. Data were analyzed by Cronbach's alpha, descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient by using SPSS/PC+ program. It was found that the mean score of the self-esteem was 3.20. The score of self-esteem in family was high and the score of self-esteem in school was low. The mean score of mental health was 1.94. The scores of depression, obsessive-compulsive and interpersonal sensitivity were high, the scores of phobic anxiety and somatization were low. There were significant differences among religions (F=2.709, p= .032), and between personalities (t=-2.285, p= .024) with respect to self esteem. There were no significant differences between general characteristics variables and mental health. However there was significant negative correlation between the mean self-esteem score and the mean mental health score (r=-.431, p= .000). In conclusion, mental health is strongly related to self-esteem. If and adolescent who suffers from mental health is not received proper treatment, his or her mental health prohibits him from managing sound social life even after grown-up. Thus, nursing intervention in adolescence should be developed to enhance the self-esteem of adolescence and to help him raise sound mind.

일 고등학교 학생이 지각한 사회적 지지와 자가간호역량과의 관계 연구

최인령,이광숙 韓國學校保健學會 2001 韓國學校保健學會誌 Vol.14 No.2

This study was designed to identify the relation between the Perceived Social Support and the Self-care Agency of high school students in a rural area. The subjects for this study were 250 students living in Chonnam province: among first grade, second grade and third grade students were 98, 89 and 63 respectively. The data were collected during the period from April 2 to 4, 2001. The instruments used in this study were the Generally Perceived Social Support Scale developed by Park, J. W.(1985) and Self-Care Agency Questionnarie developed by Deneys(1981). The data were analyzed by descriptive statistic, t-test, ANOVA, and Pearson's correlation using the SAS PC+ Program. The results were as follows: 1. The mean score of the Perceived Social Support was 3.19. 2. The mean score of the Self-care Agency was 2.65. 3. There was a significant differences in school year(F=3.11, p=.046), educational level of the father(F=3.41, p=.035) that of the mother(F=4.07, p=.019), and economic status(F=8.99, p=.000), school performance(F=16.37, p=.000) from Perceived Social Support between general characteristics. 4. There was a significant differences in economic status(F=4.55, p=.004), school performance(F=6.72, p=.002) from self care agency between general characteristics. 5. The relation between the score of the Perceived Social Support and Self-care Agency was significant(r=.49, p=.0001). The relation between the score of the direct Perceived Social Support and Self-care Agency was significant(r=.500, p=.0001) and the relation between the score of the indirect Perceived Social Support and Self-care Agency was also significant(r=.40, p=.0001). In conclusion, it was found that higher score of the Social Support was a higher level of the Self-care Agency, especially the direct Perceived Social Support. The score of the Social Support and Self-care Agency was significantly differentiated according to economic status and school performance.

비기질적인 흉통환자의 정신과적 임상 특성에 대한 연구

서세령,김진세,이현수,정인과 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.5

이 연구는 93년 9월에 5월까지 비기질적인 흉통 환자들중 정신과 진료를 거부한 22명, 정신과 진료를 받은25명과 대조 집단인 공황장애 환자 23명을 대상으로 하였다. 이들에게 불안 및 공포 상태를 평가하기 위해 Sheehan 임상 불안 척도, Spielberg 상태 - 특성 불안 검사, Sheehan 공포 척도와 우울정도를 평가하기위하여 Beck 우울 척도, 생활상의 장애를 평가하기 위해 사회 장애 척도 및 스트레스를 평가하기 위해 사회 재적응 평가 척도를 실시하였으며 다음과 같은 결과를 얻었다. 1) Sheehan 임상 불안 척도, Spielberg 특성 상태 불안 척도, Sheehan 공포 척도, Beck 우울 척도 및 사회 장애 척도에서 3군사이에 통계적으로 의미있는 차이는 없었다. 2) 사회 재적응 평가 척도에서 내과 환자가 공황장애 환자에 비해 통계적으로 유의하게 점수가 높았다. 이와 같은 결과로 비기질적인 흉통 환자들이 정신과적 장애가 있음을 강력히 시사하고 특히 최근 스트레스를 겪은 내과 환자에서 더욱 신속한 정신과적 평가와 치료가 중요하다는 것을 생각할 수 있다. 또한 이런 정신병리는 다시 기질적인 심장질환 발생의 원인이 되기도 하는 바 기기질적인 흉통 환자에 있어서 적극적인 정신과적 치료가 필요하다. Objective : We tried to compare and assess nonorganic chest pain patients and panic disorder patients in clinical manifestations. Methods : We compared the result of clinical scale for anxiety, depression, phobia and avoidance, stress, and social disability in twenty-two patients diagnosed to have nonorganic chest pain and having refused psychiatric consultation, twenty-five patients with nonorganic chest pain admitted to psychiatric department, and twenty-three panic disorder patients with no chest pain. Results : No significant difference was found among the three groups except social readjustment rating scale. Conclusion : The patients with nonorganic chest pain showed as much anxiety, depression, phobia and avoidance, stress, and social disability as the panic patients. Early psychiatric assessment and treatment of patients with nonorganic chest pain is warranted.

상악동내에 발생한 미입견치의 1예

김기령,박인용,정진선 대한이비인후과학회 1976 대한이비인후과학회지 두경부외과학 Vol.19 No.3

치과 임플랜트를 이용한 보철수복시 자연지대치와의 연결형태에 따른 응력의 광탄성학적 분석

林鍾和,李文嶺,曺仁鎬 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

The connection between natural tooth abutment and implant has been studied with various methods. This study compared the stress distribution during the function of four prosthesis with variant connection modalities design between natural tooth abutment and implant fixture. The four connection types are rigid, non-rigid, telescopic crown and free standing. Each specimen was examined and taken the photograph with 30Kg force. the results were as follows. 1. Generally, the implant fixture has more stress concentration than the natural tooth abutment. 2. The specimens using the free standing type and the telescopic crown connection showed less stress concentration than the other specimen. 3. Although maximum fringe order was not equal, stress distribution of the specimen using rigid connector was similar with that of used telescopic connection. But of the showed even stress distribution at the natural tooth abutment and implant fixture. 4. In the specimen using non-rigid connector, more and wide stress distribution was seen around implant fixture comparing with the other specimen. 5. In case of connecting the implant and natural tooth abutment, using the telescopic crown connection is adventageous in stress distribution, and manintenance of prothesis because of easy removal and reinsertion.

임플랜트에 의해 지지되는 Overdenture술식의 Bar설계변화에 따른 응력분석의 광탄성학적 연구

李濬壽,李文嶺,曺仁鎬 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

Since the concept of osseointegration was developed by Branemark, dental implant prosthesis are widely accepted by dental clinicians. There are two methods to treat edentulous patients by dental implant : One is an edentulous bone anchored fixed bridge and the other is an overdenture. The implant supported overdenture has several advantages. It is esthetically acceptable, easy to maintain good oral hygiene and more economic. Key factors that influence the success of osseointegration are quality of bone, integration between implant and bone, and loading condition. This study compared the diffrence in the stress patterns induced by variable bar design using photoelastic analysis. The results were as follows : 1. In the overdenture supported by two fixtures, three point loading on the bar showed more stress distribution than one point loading on the middle of the bar. 2. In the overdenture supported by the two fixtures, the more loading points went distally, the lager the stress became. 3. The stress distribution of the overdenture supported by four fixtures showed smaller than that of the overdenture supported by two fixtures.

Anticancer Properties of Icariside II in Human Oral Squamous Cell Carcinoma Cells

In-Ryoung Kim,Young-Seok Kim,Su-Bin Yu,Hae-Mi Kang,Hyun-Ho Kwak,Bong-Soo Park 대한구강생물학회 2016 International Journal of Oral Biology Vol.41 No.1

OSCC is currently the most common malignancy of the head and neck, affecting tens of thousands of patients per year worldwide. Natural flavonoids from plants are potential sources for novel anti-cancer drugs. Icariin is the active ingredient of flavonol glycoside, which is derived from the medical plant Herba Epimedii. A metabolite of icariin, icariside II exhibits a variety of pharmacological actions, including anti-rheumatic, anti-depressant, cardiovascular protective, and immunomodulatory functions. However, the exact mechanism causing the apoptosis-inducing effect of icariside II in OSCC is still not fully understood. In the present study, we assessed the anti-cancer effect of icariside II in OSCC cell lines by measuring its effect on cell viability, cell proliferation, and mitochondria membrane potential (MMP). Icariside II treatment of OSCC cells resulted in a dose- and time-dependent decrease in cell viability. Hoechst staining indicated apoptosis in icariside II-treated HSC cells. Icariside II inhibited cell proliferation and induced apoptosis in HSC cells, with significant increases in all present parameters in HSC-4 cells. The results clearly suggested that icariside II induced apoptosis via activation of intrinsic pathways and caspase cascades in HSC-4 cell lines. The collective findings of the study suggested that Icariside II is a potential treatment for OSCC; in addition, the data could provide a basis for the development of a novel anti-cancer strategy.

Sex Difference in the Effect of Bifidobacterium longum on Repeated Water Avoidance Stress-induced Gut Dysbiosis in Wistar Rats

Soo In Choi,Na Young Kim,Ryoung Hee Nam,Jae Young Jang,Eun Hye Kim,SungChan Ha,Kisung Kang,Wonseok Lee,Cheol Min Shin,Dong Ho Lee 대한암예방학회 2024 Journal of cancer prevention Vol.29 No.1

Dysbiosis in gut microbiota is known to contribute to development of irritable bowel syndrome. We tried to investigate the effect of Bifidobacterium longum on repeated water avoidance stress (WAS) in a Wistar rat model. The three groups (no-stress, WAS, and WAS with B. longum) of rats were allocated to sham or WAS for 1 hour daily for 10 days, and B. longum was administered through gavage for 10 days. Fecal pellet numbers were counted at the end of each 1-hour session of WAS. After 10 days of repeated WAS, the rats were eutanized, and the feces were collected. WAS increased fecal pellet output (FPO) significantly in both sexes (P < 0.001), while the female B. longum group showed significantly decreased FPO (P = 0.005). However, there was no consistent change of myeloperoxidase activity and mRNA expression of interleukin-1β and TNF-α. Mast cell infiltration at colonic submucosa increased in the female WAS group (P = 0.016). In terms of fecal microbiota, the repeated WAS groups in both sexes showed different beta-diversity compared to control and WAS with B. longum groups. WAS-induced mast cell infiltration was reduced by the administration of B. longum in female rats. Moreover, administration of B. longum relieved WAS-caused dysbiosis, especially in female rats. In conclusion, B. longum was beneficial for WAS-induced stress in rats, especially in females.