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기관지천식 환자의 기관지분비물내 총 IgE 항체치 연구에서 유도객담검사의 유용성
김상돈,서창희,김희연,남동호,박해심 (Sang Don Kim,Chang Hee Suh,Hee Yeon Kim,Dong Ho Nahm,Hae Sim Park) 대한천식알레르기학회 1998 천식 및 알레르기 Vol.18 No.2
Background: IgE antibodies have been considered to play an important role in the pathogenesis of atapic asthma. However, there have been only few studies on the role of IgE in airway secretion in the pathogenesis of bronchial asthma. This might be partly due to difficulty in sampling of airway seceretion from asthmatic patients. Recently, sputum induction method by inhalation of nebulized hypertonic saline was developed, and proved to be valid and useful method for obtaining airway secretion from asthmatic patients for studying air- way inflammation. %jective and method: To evaluate the usefulness of sputum induction method for studying IgE antibodies in airway secretion from atopic asthmatic patients, total IgE levels in induced sputum from 54 atopic asthmatics were measured by enzyme-linked immunosorbent assay(ELISA) and tried to find an association with sputum eosinophilia. Result: Total IgE levels in induced sputum were significantly higher in atopic asthmatic patients(1.27+82.066 IU/ml) than in controls(0.203+0.291 IUgmP)(p<0.05). In atopic asthmatic patients, total IgE levels in induced sputum were not significantly different between patients with and without sputum eosinophilia(>5% of 200 counted leukocytes). There was a significant correlation of total IgE levels between induced sputum and serum in atopic asthmatic patients(r=0.60, p<0.05). Total IgE levels in induced sputum(1.278+ 2.066) were significantly higher than saliva sample(0.504 + 1.111 IU/ml) from atopic asthmatic patients(p<0.05). Conclusion '. These results suggest that total IgE levels are increased in the induced sputum of atopic asthmat,ic patients and sputum induction method is a useful tool for study- ing IgE antibodies in airway secretion from asthmatic patients.
Pyrolytic characteristics of Jatropha seedshell cake in thermobalance and fluidized bed reactors
김상돈,Sung Won Kim,Dong Kyoo Park 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.5
Pyrolytic kinetic parameters of Jatropha seedshell cake (JSC) were determined based on reaction mechanism approach under isothermal condition in a thermobalance reactor. Avrami-Erofeev reaction model represents the pyrolysis conversion of JSC waste well with activation energy of 36.4 kJ mol−1 and frequency factor of 9.18 s−1. The effects of reaction temperature, gas flow rate and feedstock particle size on the products distribution have been determined in a bubbling fluidized bed reactor. Pyrolytic bio-oil yield increases up to 42 wt% at 500 oC with the mean particle size of 1.7 mm and gas flow rate higher than 3Umf, where the maximum heating value of bio-oil was obtained. The pyrolytic bio-oil is characterized by more oxygen, lower HHVs, less sulfur and more nitrogen than petroleum fuel oils. The pyrolytic oil showed plateaus around 360 oC in distribution of components’ boiling point due to high yields of fatty acid and glycerides.
파종성 악성 핍지신경교종 환자에서 시행한 뇌실내 Methotrexate의 효과 - 증례보고 -
김상돈,정용구,김세훈,임동준,조태형,이훈갑,서중근,이기찬,Kim, Sang-Don,Chung, Yong-Gu,Kim, Se-Hoon,Lim, Dong-Jun,Cho, Tae-Hyung,Lee, Hoon-Gap,Suh, Jung-Keun,Lee, Ki-Chan 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.7
Oligodendrogiomas account for about 4 per cent of intracranial gliomas and surgery is known to be an essential first step to establish an accurate diagnosis and when oligodendrogliomas recur with or without anaplastic features after initial resection, radiation and chemotherapy consisting of the administration of procarbazine, lomustine, and vincristine are usually indicated. We report our experience of an excellent result with intraventricular methotrexate chemotherapy for a patient with disseminated anaplastic oligodendroglioma. A 29-year-old male patient presented with diplopia and headache for two months. MRI showed a irregular, faintly enhanced mass in the posterior fossa. The hisotological diagnosis was an anaplaplastic oligodendroglioma and he was treated with chemotherapy of PCV regimen and radiotherapy followed by surgery. CSF dissemination was revealed by a follow-up MRI during the period. Intraventricular methotrexate(0.175mg/kg) was given twice a week for 4 weeks through ommaya reservoir and the size of the multiple tumors was decreased significantly on follow-up MRI. This case report suggests that an aggressive treatment involving intravent-ricular chemotherapy may be helpful even when anaplastic oligodendrogliomas disseminates to leptomeninges.
보문 : XAD 및 FT-IR을 이용한 영산강수계 광주시 유역 자연유기물질의 분포특성 연구
이동진 ( Dong Jin Lee ),전강민 ( Kang Min Chon ),김상돈 ( Sang Don Kim ),정수정 ( Soo Jung Jung ),이경희 ( Kyung Hee Lee ),황태희 ( Tae Hee Hwang ),임병진 ( Byung Jin Lim ),조재원 ( Jae Weon Cho ) 한국하천호수학회(구 한국육수학회) 2011 생태와 환경 Vol.44 No.4
This study investigated the characteristics of natural organic matter (NOM) with tXAD resin and FT-IR in the Yeongsan river system of Gwangju region. NOM fractionation by XAD 8/4 resins was used to classify hydrophobic and hydrophilic substances. FTIR was applied to classify functional groups in the structure of NOM. In the XAD investigation, most of the four site-samples were mainly hydrophilic substances. In March, hydrophilic substances were dominant in the Gwangju 1 site (GJ-1), while hydrophilic substances were dominant for the other sites. In May, samples of all four sites were hydrophilic with a vigorous activity of microorganism due to increasing temperatures. The October results were very similar with those from March. In the FT-IR investigation, most of the broad and large peaks were assigned to the aliphatic group, particularly the OH group, C-H, C-H2, C-H3, and C-O alcohol group. All were related to hydrophilic substances. Other peaks showed the aromatic group, particularly the C=O (Ketone) Group. As a result, there is an identification of NOM in the Yeongsan river system composing mainly of hydrophilic substances and functional groups (OH, C-H etc.) of the aliphatic compound.
비점오염원 처리를 위한 자유수면형 인공습지에서 질소형태의 유입이 토양 미생물상에 미치는 영향 (초록)
이상규 ( Sang Gyu Lee ),서동철 ( Dong Cheol Seo ),최익원 ( Ik Won Choi ),강세원 ( Se Won Kang ),서영진 ( Young Jin Seo ),임병진 ( Byung Jin Lim ),이준배 ( Jun Bae Lee ),김상돈 ( Sang Don Kim ),허종수 ( Jong Soo Heo ),조주식 ( Ju S 한국토양비료학회 2012 한국토양비료학회 학술발표회 Vol.2012 No.-
최동호 ( Dong Ho Choi ),정재운 ( Jae Woon Jung ),윤광식 ( Kwang Sik Yoon ),진소현 ( So Hyun Jin ),최우영 ( Woo Young Choi ),최우정 ( Woo Jung Choi ),김상돈 ( Sang Don Kim ),임병진 ( Byung Jin Yim ),최유진 ( Yu Jin Choi ) 한국물환경학회 2010 한국물환경학회지 Vol.26 No.6
Runoff ratio of paddy fields for the application of Event Mean Concentration (EMC) method was studied. To measure actual runoff ratio of paddy fields, a field monitoring was conducted for 2008 ~ 2009 period. Long-term rainfall data of four cities in major river basins were analyzed and weighting factors were developed to consider temporal and spatial variation of rainfall distribution of Korean peninsula. The observed runoff ratio ranged 0.00 ~ 1.20 and arithmetic mean were 0.25, respectively. However, the representative runoff ratio for paddy fields was determined as 0.41 according to the method suggested by National Institute of Environmental Research (NI ER).
연구보문 : 생태환경 ; 단일 통풍형과 이중 통풍형 인공습지시스템의 하수처리 효율 비교
서동철 ( Dong Cheol Seo ),임석천 ( Seok Cheon Lim ),조인성 ( In Seong Jo ),이병주 ( Byeong Ju Lee ),이홍재 ( Hong Jae Lee ),김상돈 ( Sang Don Kim ),이준배 ( Jun Bae Lee ),조주식 ( Ju Sik Cho ),허종수 ( Jong Soo Heo ) 韓國環境農學會 2009 한국환경농학회지 Vol.28 No.3
농어촌 등에서 소규모로 발생하는 하수처리를 위한 환경 친화형 자연정화공법인 인공습지 하수처리장 개발을 위하여 수직흐름조(VF)-수평흐름조(HF) 인공습지 시스템을 수직흐름조는 현행 단일 통풍 구조에서 이중 통풍 구조로, 수평흐름조는 깊이를 현행 1.0 m에서 1.3 m로 하여 체적은 같으면서 표면적을 줄여 시공한 다음, 수직흐름조 통풍방법별, 수평흐름조 깊이별 및 하수부하량에 따른 수처리 효율을 조사하였다. 수직흐름조 통풍 방법에 따른 수처리 효율을 조사한 결과 BOD 및 COD는 이중 통풍형 구조가 단일 통풍형 구조에 비해 높은 처리효율을 보였다. 하지만 총 질소와 총 인은 두 통풍형 구조 모두 큰 차이 없이 유사한 결과를 보였다. 따라서 수직흐름조의 최적 통풍방법은 이중통풍형 구조이었다. 수평흐름조 깊이에 따른 수처리 효율을 조사한 결과 BOD, COD, 총 질소 및 총 인 함량은 수평흐름조 깊이에 따라 별 차이가 없었지만, 수평흐름조 깊이 1.3 m의 경우 인공습지 하수처리장의 시공시 부지면적을 감소시킬 수 있을 것으로 판단되므로 깊이 1.0 m에 비해 경제성과 유지관리면에서 바람직할 것으로 생각된다. 따라서 수평흐름조의 최적 깊이는 1.3 m이었다. 농어촌 지역에서 소규모로 발생하는 하수의 하수부하 변동에 대한 대응성을 조사하기 위하여 하수부하량에 따른 수처리 효율을 조사한 결과 BOD처리율은 하수부하량이 적을수록 약간 높았으며, COD 및 SS는 하수부하량에 따라서 별 차이가 없었고, 동일한 하수부하량에서는 이중 통풍형 공법이 대조구인 단일 통풍형 공법에 비해 높은 처리효율을 보였다. 총 질소 및 총 인 처리효율도 하수부하량이 증가함에 따라 처리효율이 점점 감소되는 경향이었고, 동일한 부하량에서는 이중 통풍형 공법이 단일 통풍형 공법에 비해 처리율이 약간 높았다. 따라서 하수처리장 공법별 및 하수부하량에서의 하수처리효율과 경제성 및 유지 관리비를 고려해 볼 때 농어촌 등에서 소규모로 발생하는 하수를 효과적으로 처리하기 위한 인공습지 하수처리장은 수직흐름조 통풍방법이 이중 통풍형 구조이며 수평흐름조의 깊이가 1.3 m인 이중 통풍형 공법이 되어야 할 것으로 판단된다. To develop environmentally friendly constructed wetlands(CWs) for treating domestic sewage which was produced in farming and fishing village, the efficiency of water treatment at different ventilation systems in the vertical bed, depths of horizontal bed, and sewage loads was investigated. In the vertical bed, BOD and COD by duplex ventilation system were lower than those by single ventilation system. But T-N and T-P concentrations by both ventilation systems in the vertical bed were little different. In the horizontal bed, BOD, COD, T-N and T-P in 1.0 m and 1.3 m depths were little different. To reduce the CWs` area and to improve the pollutant removal efficiencies, the optimum depth of horizontal bed was 1.3 m. In single and duplex ventilation CWs, the removal rate of BOD, COD, SS, T-N and T-P decreased slightly with the sewage load increases. In same sewage load conditions, the removal rates of BOD, COD, SS, T-N and T-P by duplex ventilation CWs were higher than those by single ventilation CWs. In summary, to effectively treat domestic sewage from farming and fishing village, the optimum constructed wetlands would be the duplex ventilation CWs.