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      • KCI등재

        Hot Deformation Behavior and Recrystallization Mechanism in an As-Cast CoNi-Based Superalloy

        Yong Guan,Yongchang Liu,Zongqing Ma,Huijun Li,Hongyao Yu 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.6

        The hot deformation behavior of as-cast CoNi-based superalloy was investigated by means of hot compression tests. Thecorresponding microstructure evolution after hot deformation was examined by optical microscope, as well as the TEMtechnique. The constitutive equation and processing map as a function of deformation temperature and strain rate were developed. Results show that the efficiency peak of the processing map is 0.38 at the temperature of 1130 °C and the strain rate of0.01 s−1. The discontinuous dynamic recrystallization (DDRX) related to the strain-induced grain boundary migration (SIBM)is the dominant recrystallization mechanism during hot working. Meanwhile, the DRX also occurs by forming sub-grainsaround MC carbides and shear band. In addition, the existence of fine γ′ precipitates are found to retard the recrystallization.

      • KCI등재

        RO 및 NF막에서의 부식질에 의한 Fouling 및 미량오염물질의 제거

        왕창근,차준철,이용현,김수동,류주환 대한상하수도학회 2004 상하수도학회지 Vol.18 No.1

        This study investigated the phenomena of membrane fouling by NOM and the effect of the fouling on removal of micro-pollutants. NOM has a great effect on decline of permeate flux. Permeate flow rate was reduced by 88% in RO and 34.8% in NF for 323hr operation period. Removal rate of UV_(254), is 87.4% in RO and 78.5% in NF and removal rate of DOC is 42.7% in RO and 32.9% in NF for 2㎎/l humic acid. Removal efficiency of the micmpollutants by the RO and NF membranes fouled by humic acid was mostly lower than that by the new membrane. The concentration polarization which affects the flux and the rejection was thought to occur in the active layer of the membrane, as the membrane was getting fouled.

      • SCOPUS

        Relationships between Inbound Tourism, Financial Development, and Economic Growth: An Empirical Study of Fujian Province, China

        An Lin LIU(An Lin LIU),Yong Cen LIU(Yong Cen LIU) 한국유통과학회 2023 The Journal of Asian Finance, Economics and Busine Vol.10 No.2

        This paper mainly studies the relationship between financial development, inbound tourism development, and economic growth rate in Fujian Province, China. This study uses the data of real GDP, foreign exchange income from international tourism, and financial interrelations ratio from 1994 to 2019. In the analysis process, the Johansen cointegration test is first used to analyze whether the three have a long-term equilibrium relationship. Then the vector error correction model is established to test the restrictive relationship among the three. Next, the Granger causality test assesses whether the three have a causal relationship. Finally, the contribution rate of the three is analyzed by variance decomposition. The above methods show the following conclusions: first, the three have a long-term equilibrium relationship. Secondly, in the short term, local economic growth is constrained by inbound tourism and financial development. Thirdly, there is a causal relationship between economic growth and inbound tourism in Fujian, while there is a unidirectional causal relationship between financial development and economic growth, financial development, and inbound tourism. Fourthly, the contribution rate of inbound tourism to economic growth fluctuations in Fujian is higher than that of financial development.

      • KCI등재

        Optimization of preparation and properties of Gardenia yellow pigment-loaded alginate beads

        Yong Liu,Qing Zhou,Yan-Mei He,Xiu-Yun Ma,Lin-Na Liu,Yong-Jian Ke 한국화학공학회 2021 Korean Journal of Chemical Engineering Vol.38 No.8

        Gardenia yellow pigment (GYP) loaded alginate beads were prepared by the ionic gelation technique, and the preparation parameters were optimized by response surface methodology for high encapsulation efficiency. The optimized parameters were alginate concentration of 3.3%, CaCl2 concentration of 2.4%, and GYP concentration of 3.2mg/mL, under which the encapsulation efficiency was 73.61%. The surface morphology and bead size analysis showed that the GYP-loaded alginate beads had a roughly spherical morphology with a wrinkled surface, and their average diameter was 0.87 mm. In vitro release test revealed that the GYP release had a pH-dependent release profile and a two-step release process. The Rigter-Peppas model was the most proper model to assess the GYP release from alginate beads. The release mechanism of GYP at pH 1.2 and 7.4 was non-Fickian transport and case-II transport, respectively. The 2,2-diphenyl-1-picrylhydrazyl assay indicated that the encapsulated GYP had effectively maintained 82.56% of the antioxidant activity.

      • KCI등재

        Developing Brønsted–Lewis acids bifunctionalized ionic liquids based heteropolyacid hybrid as high-efficient solid acids in esterification and biomass conversion

        Yong Liu,Yuefeng Wu,Miaojun Su,Weihua Liu,Xiying Li,Fujian Liu 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.92 No.-

        A class of Brønsted–Lewis acid bifunctionalized ionic liquids based heteropolyacid hybrid (BLA-ILs-HPA)solid acids were developed by combining the double sulfonic groups grafted, ionic liquids basedheteropolyacid hybrid with Lewis acidic centers (M = Zn, Co, Fe, Ni, Cu). The prepared BLA-ILs-HPA showboth Brønsted and Lewis acidic sites with extremely-high acid strength and enhanced stabilities, asdetermined by FT-IR, Py-IR, TG, XPS and 31P solid state NMR results. BLA-ILs-HPA were successfullyapplied in esterification camphene with acetic acid to produce isobornyl acetate, and dehydration ofglucose to produce 5-hydrozymethylfural. BLA-ILs-HPA show enhanced catalytic activities in comparisonwith various acid catalysts. The effects of reaction temperatures, initial reactant molar ratio, catalystdosage, and reaction time were studied in detail. The optimal reaction conditions were obtained, and theexperimental data was successfully correlated by a pseudohomogeneous (PH) reaction kinetic model inthe temperature range of 313.15–333.15 K. The calculated values obtained by the reaction kinetic modelwere in good agreement with the experimental data. Moreover, as a heterogeneous reaction catalyst,BLA-ILs-HPA can be recovered by simple treatment. After six times cycling, the decreasing in the catalyticactivity of BLA-ILs-HPA could not be observed significantly, suggesting their good reusability.

      • KCI등재

        In Vitro Evaluation and Monitoring of the Expression Level and Localization of Aldose Reductase Using Functionalized Quantum Dots and EGFP

        Xiaomin Liu,Chengbin Yang,Jing Liu,Jianwei Liu,Rui Hu,Hongwei Lian,Guimiao Lin,Liwei Liu,Ken-Tye Yong,Ling Ye 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.4

        The optimization of aldose reductase (AR) expression levels and tracking of the AR expression sites within the cell is an essential step in developing a platform for the effective production of aldose reductase inhibitors (ARIs). In this study, we have demonstrated the use of both immunocytochemistry and quantum dots-based immunofluorescence techniques for observing and detecting the expression level and localization of AR in the cytoplasm and cell membrane of a eukaryotic cell model with high levels of AR protein expression. Our results show that high expression levels of human AR can be achieved using the eukaryotic cell model that we have developed. The overexpressed AR can be used for translational studies of hAR and the screening of ARIs. More importantly, the use of the established quantum dots-based immunofluorescence technique in the intracellular labeling of AR allows the determination of the expression and distribution of the AR gene. Overall, the use of the interdisciplinary approach of both genetic engineering and quantum dot-based immunofluorescence allows not only the effective production of a desired protein, but also the determination of the cellular localization of such an expressed protein.

      • Comprehensive Analysis of Vascular Endothelial Growth Factor-C Related Factors in Stomach Cancer

        Liu, Yong-Chao,Zhao, Jing,Hu, Cheng-En,Gan, Jun,Zhang, Wen-Hong,Huang, Guang-Jian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5

        Background: Vascular endothelial growth factor-C (VEGF-C), which contributes to lymphatic metastasis (LM) in malignant disease, is one of the most important factors involved in physical and pathological lymphangiogenesis. Some VEGF-C related factors such as sine oculis homeobox homolog (SIX) 1, contactin (CNTN) 1 and dual specificity phosphatase (DUSP) 6 have been extensively studied in malignancies, but their expression levels and associations have still to be elucidated in stomach cancer. Methods: We detected their expression levels in 30 paired stomach cancer tissues using quantitative real-time reverse transcription-PCR (qRT-PCR). The expression and clinical significance of each factor was analyzed using Wilcoxon signed rank sum test. The correlation among all the factors was performed by Spearman rank correlation analysis. Results: The results suggest that VEGF-C and CNTN1 are significantly correlated with tumor size, SIX1 with the age and CNTN1 also with the cTNM stage. There are significant correlations of expression levels among VEGF-C, SIX1, CNTN1 and DUSP6. Conclusions: There exists an important regulatory crosstalk involving SIX1, VEGF-C, CNTN1 and DUSP6 in stomach cancer.

      • Short Low Concentration Cisplatin Treatment Leads to an Epithelial Mesenchymal Transition-like Response in DU145 Prostate Cancer Cells

        Liu, Yi-Qing,Zhang, Guo-An,Zhang, Bing-Chang,Wang, Yong,Liu, Zheng,Jiao, Yu-Lian,Liu, Ning,Zhao, Yue-Ran Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

        Background: Prostate cancer is one of the main causes of cancer death, and drug resistance is the leading reason for therapy failure. However, how this occurs is largely unknown. We therrfore aimed to study the response of DU145 cells to cisplatin. Materials and Methods: Du145 prostate cancer cells were treated with a low dose of cisplatin for 24 h and cell viability and number were determined by MTT assay and trypan blue exclusion assay, respectively. The real time polymerase chain reaction (PCR) was used to assess responses to cisplatin treatment. Results: After 24h $2{\mu}g/ml$ treatment did not result in significant reduction in cell viability or number. However, it led to enhanced cancer cell invasiveness. E-cadherin mRNA was reduced, and vimentin, Snail, Slug, metalloproteinase 9 (MMP9) mRNA expression increased significantly, a feature of epithelial-mesenchymal transition (EMT). Conclusions: Short time low concentration cisplatin treatment leads to elevated invasiveness of DU145 cancer cells and this is possibly due to EMT.

      • SCOPUSKCI등재

        Incremental Fuzzy Clustering Based on a Fuzzy Scatter Matrix

        Liu, Yongli,Wang, Hengda,Duan, Tianyi,Chen, Jingli,Chao, Hao Korea Information Processing Society 2019 Journal of information processing systems Vol.15 No.2

        For clustering large-scale data, which cannot be loaded into memory entirely, incremental clustering algorithms are very popular. Usually, these algorithms only concern the within-cluster compactness and ignore the between-cluster separation. In this paper, we propose two incremental fuzzy compactness and separation (FCS) clustering algorithms, Single-Pass FCS (SPFCS) and Online FCS (OFCS), based on a fuzzy scatter matrix. Firstly, we introduce two incremental clustering methods called single-pass and online fuzzy C-means algorithms. Then, we combine these two methods separately with the weighted fuzzy C-means algorithm, so that they can be applied to the FCS algorithm. Afterwards, we optimize the within-cluster matrix and betweencluster matrix simultaneously to obtain the minimum within-cluster distance and maximum between-cluster distance. Finally, large-scale datasets can be well clustered within limited memory. We implemented experiments on some artificial datasets and real datasets separately. And experimental results show that, compared with SPFCM and OFCM, our SPFCS and OFCS are more robust to the value of fuzzy index m and noise.

      • On the Origin of Improved Charge Transport in Double-Gate In–Ga–Zn–O Thin-Film Transistors: A Low-Frequency Noise Perspective

        Yong Xu,Chuan Liu,Amegadez, Paul Seyram K.,Gi-Seong Ryu,Huaixin Wei,Balestra, Francis,Ghibaudo, Gerard,Yong-Young Noh IEEE 2015 IEEE electron device letters Vol.36 No.10

        <P>Low-frequency noise (LFN) in double-gate (DG) In-Ga-Zn-O (IGZO) thin-film transistors (TFTs) is studied to investigate the origin of performance improvement. We found that thinning down the IGZO film enhances such improvements. With 7-nm IGZO, the mobility is raised by a factor of 3.77, and the subthreshold slope is reduced to 0.17 V/decade from single-gate to DG mode. Device simulations show that bulk transport inside IGZO film emerges as the two gates field effects get coupled. The LFN results reveal a transport transition from surface to bulk and disclose the superior bulk transport that experiences slight phonon scattering with a small Hooge parameter alpha(H) = 4.44 x 10(-3), whereas the surface transport undergoes serious charge trapping with surface trap densities about 2 x 10(11) eV(-1)cm(-2).</P>

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