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      • 유전 알고리듬을 이용한 퍼지 규칙 베이스의 자동생성

        김용호,심귀보,전홍태,박세희 중앙대학교 생산공학연구소 1992 생산공학연구소 논문집 Vol.1 No.1

        Fuzzy logic rule based controller has many desirable advantages, which are simple to implement on the real time and need not the information of structure and dynamic characteristics of the system. Thus, nowadays, the scops of the application of the fuzzy logic controller becomes enlarged. But, if the controlled plant is a time-varying/nonlinear system, it is not easy to construct the fuzzy logic rules which need the knowledge of an expert. In this paper, an approach by which the logic control rules can be auto-generated using the genetic algorithm that is known to be very effective in the optimization problem will be proposed and the effectiveness of the proposed approach will be verified by computer simulation of the 2 d.o.f. planner robot.

      • 적응 뉴럴-퍼지 제어시스템의 설계에 관한 연구

        전홍태,심귀보,김용호,김성현,최영길 중앙대학교 생산공학연구소 1992 생산공학연구소 논문집 Vol.1 No.2

        지능 제어기를 구현하기 위한 한 방법으로 본 논문은 퍼지 논리와 신경망 제어기법을 합성 결합한 새로운 형태의 FNC(Fuzzy-Neural Controller)와 적응 뉴럴-퍼지 제어 방식을 제안한다. 제안되는 뉴럴-퍼지 시스템은 적응성과 학습능력의 두가지 주요한 기능을 갖는다. 먼저 FNC에서의 퍼지 규칙의 전건부와 후건부는 클러스터링 방법과 다층신경망에 의해 구현된다. 그리고 MNN(Model Neural Network)에서의 다층신경망은 수학적 모델링이 어려운 플랜트의 상태를 동정하는데 도입하고 동적인 환경에 적응하도록 제어기에 교사 신호를 제공한다. FNC와 MNN으로 구성된 적응 제어시스템은 학습 알고리듬으로 역전파 학습 알고리듬이 사용된다. 제안된 방식의 효용성은 2 d.o.f 로보트 매니퓰레이터와 cart-pole의 모의 실험으로 입증된다. As an approach to develope the intelligent control scheme, this paper will propose an adaptive neural-fuzzy control scheme. The proposed neural-fuzzy control system, which consists of the Fuzzy-Neural Controller(FNC) and Model Neural Network(MNN), has two important characteristics of adaptation and learning. In the FNC, the antecedence and consequence of the fuzzy rule are constructed by a clustering method and a multi-layer neural network. And in the MNN, a multi-layer neural network is utilized to identify a unknown controlled plant and provides the FNC with the teaching signal. After constructing the adaptive control system using the FNC and the MNN, the error back propagation algorithm has been adopted as a learning technique. The effectiveness of the proposed scheme will be demonstrated by computer simulations of a cart-pole and a two d.o.f. robot manipulator.

      • KCI등재

        수리조선 작업장에서의 공기중 석면 노출에 관한 연구

        심상효,정희태,송기민,김윤신,강용선,Sim, Sang-Hyo,Chung, Hee-Tae,Song, Ki-Min,Kim, Yoon-Shin,Kang, Yong-Seon 한국환경보건학회 2008 한국환경보건학회지 Vol.34 No.4

        This paper aims to provide basic data for work environment control, prevention of worker exposure to asbestos and improvement of air quality to protect workers ‘health after measuring the level of airborne asbestos and workers' exposure in a shipbuilding repair businesses. For this study, a total of 27 samples were collected from 27 workers who had been exposed to asbestos during engine, piping, boiler and other manufacturing processes in 'A' Shipbuilding Repair Company in Gyeongnam. This research was conducted from Oct. 1 to 30, 2007 and had the following results: The target group (27 workers) consisted of all men with an average age of 35.9 years and 6.6 years of work on average. Among them, fifteen 15 (55.6%) were smokers. In terms of their duties at work, there were 12 plumbing repair engineers (44.4%), 8 boiler repair engineers (29.6%) and 7 engine engineers (25.9%). The geometric mean concentration of airborne asbestos was 0.004 f/cc. A total of 4 samples exceeded the exposure limit. In particular, three exceeded the legal limit by more than double, which means that some workers have been highly exposed to asbestos. In terms of the concentration of asbestos fibres by work process, plumbing repair was the highest (0.0071 f/cc($0.001{\sim}0.57\;f/cc$)) while boiler was the lowest (0.0015 f/cc($0.001{\sim}0.007\;f/cc$)). Based on this study, proper action needs to be taken as soon as possible to protect workers from the threat of asbestos.

      • KCI우수등재

        아침 식사시간의 다른 사람들에서 혈장 그렐린의 변화

        이상엽,김윤진,김형회,손한철,전태용,심문섭 대한비만학회 2002 The Korean journal of obesity Vol.11 No.2

        연구배경 : 최근 식욕조절인자로 관심이 집중되고 있는 그렐린(ghrelin)은 식사 전후로 독한 일중변동을 보인다. 하지만, 지금까지는 실험적으로 일정한 열량의 표준 음식을 일정한 식사시간에 공급한 이후 그렐린의 농도 변화를 관찰하였다. 저자 등은 평소 아침 식사시간이 각기 다른 사람들에서 아침 식사 전후의 혈장 그렐린 농도 변화를 관찰하여 향후 외래 환경에서도 그렐린 관련 연구가 가능하도록 기초 자료를 제공하고자 하였다. 방법 : 연구에 대한 설명을 듣고 동의한 23.4 ~ 35.5세 사이의 비교적 건강한 동양인 남자 4명을 대상으로 하였다. 신체 계측을 한 후 이중 에너지 방사선 측정법 (Lunar prodigy, GE medical systems, Waukesha, Wisconsis, USA, 이하 DEXA)으로 체지방을 측정하였다. 연구 대상자 모두 평소 아침 식사시간이 일정하였지만 연구 시작 2주전부터 아침 식사시간을 엄격히 고정하도록 하였다. 스트레스가 없는 상태에서 아침 식사를 하지 않는 지원자는 오전 6시 30분부터, 나머지는 아침식사 시간 1시간 전부터 1시간 간격으로 점심 식사 전인 오전 11시 30분까지 채혈하였다. 각각의 검체로 부터 혈장 그렐린은 상업적인 방사선면역측정법 (Phoenix Pharmaceuticals, Inc., Belmont, CA)으로 측정되었다. 랩틴은 Ⅰ-125 표지 랩틴을 이용한 이중항체 방사선면역측정법으로, 혈장 인슐린은 항체 부착관을 이용한 방사선면역측정법으로, 혈당은 포도당산화 효소법에 의해 Synchron LX 20 (Beckman Coulter, Inc, Fullerton, USA)으로 측정하였다. 결과 : 연구 대상자의 체질량지수는 22.9 ~ 27.1 kg/㎡이었고, 허리둘레는 80.3 ~ 93.3 cm이었다. DEXA로 측정한 결과 전체 체지방과 체부지방 비율은 각각 27.1 ~ 31.8%와 32.7 ~ 32.4%이었다. 아침 식사를 하지 않는 자를 제외한 나머지 연구 대상자의 아침 식사 직전의 식후 2시간의 혈장 그렐린 농도는 각각 113.0 ~ 800.0 pg/mL, 78.3 ~ 553.0 pg/mL이었고 랩틴 농도는 각각 4.9 ~ 5.1 ng/mL, 4.4 ~ 4.7 ng/mL 이었다. 혈장 그렐린 랩틴 농도는 아침 식사 직전에 비해 식사 2시간 후 각각 7.2 ~ 30.9%와 7.8 ~ 10.2%감소되었다. 아침식사를 하지 않는 대상자의 경우 인슐린과 혈당치가 변화가 없음에도 불구하고 혈장 그렐린 농도는 오전 7시 30분에 가장 낮았다. 그 외 연구 대상자에서는 각기 다른 시간이더라도 아침 식사 2시간 후의 혈장 그렐린 농도가 가장 낮았다. 결론 : 평소 아침 식사시간이 다른 사람들에게서 혈장 그렐린 농도는 각기 다른 아침 식사 2 시간 후에 가장 낮았다. 아침 식사를 하지 않는 경우에는 혈장 그렐린 농도가 오전 7시 30분에 가장 낮았다. Background : Recently, the particular interest is on ghrelin, the dietary control factor among many scientists and it a toxic diurnal variations has been demonstrated before and after meal. However, the experimental approach has been only to see the changes in the concentration of ghrelin after intake of meals standardized with fixed calories at scheduled meal hours. the authors of this particular experiment have tried to observe and record the changes in concentrations of plasma ghrelin of persons with different breakfast hours. This might help in providing a basis for further possible studies in outpatient setting. Method : A group of four relatively healthy males whose ages between 23.4 and 35.5 with prior agreements were selected for this study. After body measurements, body lipid status was measured based on Lunar prodigy (GE medical systems, Waukesha, Wisconsin, USA) which is also referred to as DEXA. All of the selected persons had somewhat fixed breakfast time; however, they were asked to strictly keep their breakfast time fixed and steady starting two weeks before the beginning of experiment. The bloods of those who skip their breakfast without any particular stress were sampled at 6:30 AM, whereas the rest had different schedule, whose bloods were sampled every hour starting 1 hour before the first meal of the day till just before lunch (11:30 Am). From each blood sample, the level of plasma ghrelin was measured using the commercial radioimmune assay (Phoenix Pharmaceuticals, Inc., Belmont, CA). Leptin was measured with double antibody radioimmune assay using Ⅰ-125 labelled leptin, plasma insulin with radioimmune assay using antibody attachment tube, and blood sugar with Synchron LX20 (Beckman Coulter, Inc, Fullerton, USA) using glucosylation enzyme method. Result : The body mass index of the volunteers was 22.9 ~ 27.1 kg/㎡, with 80.3 ~ 93.3 cm waist circumference. Based on measurements by DEXA, the rates of total body lipid and trunk lipid were each 27.1 ~ 31.8% and 32.7 ~ 32.4%, respectively. The concentrations of plasma ghrelin of those who consume their breakfast before and 2 hour after their breakfast are 113.0 ~ 800.0 pg/mL and 78.3 ~ 553.0 pg/mL. The concentrations of leptin are 4.9 ~ 5.1 ng/mL and 4.4 ~ 4.7 ng/mL. Compared to the concentration of plasma ghrelin and of leptin recorded just before breakfast, it showed 7.2 ~ 30.9% and 7.8 ~ 10.2% decrease, respectively, 2 hours after breakfast. For those who skip their breakfast, the plasma concentration of ghrelin was recorded the lowest at 7:30 AM, even though there was no change in insulin and blood sugar. The rest of the subjects had their lowest plasma ghrelin concentration at 2 hours after breakfast, despite their different meal schedule. Conclusion : The persons with different breakfast hours had their lowest plasma concentration of ghrelin at 2 hours after breakfast. In contrast, the persons who skip their breakfast had their lowest concentration at 7: 30 AM.

      • SCOPUSSCIEKCI등재
      • KCI등재후보

        위절제술 환자의 표준진료지침 개발 및 적용 효과

        김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

        Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

      • SCOPUS

        The Analysis of Slice-Induced Factors in Golf Swing Using a 3D Motion Capture System

        Sim, Tae Yong,Oh, Seung Eel,Lee, Sang Sik,Mun, Joung H. Trans Tech Publications, Ltd. 2006 Key Engineering Materials Vol.321 No.-

        <P>In golf, it is crucial that unintended shots, such as slices, be minimized. However, it has proven rather difficult to improve golf performance via investigations of the causes of slicing, as this particular phenomenon is induced by a cooperative effect by each segment of the body, rather than by a single postural anomaly. Thus, the objective of this study was to isolate and characterize the factors causing slicing, and to present possibilities for the improvement of golf performance via the minimization of the number of slices executed, using a three dimensional motion capture system, combined with multiple regression analysis, artificial neural network, and fuzzy logic techniques. This study obtained some interesting results, such as the following: (1) We isolated 9 slice-inducing factors, using a stepwise method. (2) Our artificial neural network (ANN) accurately separated 'slice' from 'normal' shots (classification rate: 100%). (3)We could present the possibility of reducing the number of slice using the fuzzy logic. We expect that our data might be eventually used to improve golf performance.</P>

      • SCIESCOPUSKCI등재

        Fabrication, Estimation and Trypsin Digestion Experiment of the Thermally Isolated Micro Teactor for Bio-chemical Reaction

        Sim, Tae-Seok,Kim, Dae-Weon,Kim, Eun-Mi,Joo, Hwang-Soo,Lee, Kook-Nyung,Kim, Byung-Gee,Kim, Yong-Hyup,Kim, Yong-Kweon The Institute of Electronics and Information Engin 2005 Journal of semiconductor technology and science Vol.5 No.3

        This paper describes design, fabrication, and application of the silicon based temperature controllable micro reactor. In order to achieve fast temperature variation and low energy consumption, reaction chamber of the micro reactor was thermally isolated by etching the highly conductive silicon around the reaction chamber. Compared with the model not having thermally isolated structure, the thermally isolated micro reactor showed enhanced thermal performances such as fast temperature variation and low energy consumption. The performance enhancements of the micro reactor due to etched holes were verified by thermal experiment and numerical analysis. Regarding to 42 percents reduction of the thermal mass achieved by the etched holes, approximately 4 times faster thermal variation and 5 times smaller energy consumption were acquired. The total size of the fabricated micro reactor was $37{\times}30{\times}1mm^{3}$. Microchannel and reaction chamber were formed on the silicon substrate. The openings of channel and chamber were covered by the glass substrate. The Pt electrodes for heater and sensor are fabricated on the backside of silicon substrate below the reaction chamber. The dimension of channel cross section was $200{\times}100{\mu}m^{2}$. The volume of reaction chamber was $4{\mu}l$. The temperature of the micro reactor was controlled and measured simultaneously with NI DAQ PCI-MIO-16E-l board and LabVIEW program. Finally, the fabricated micro reactor and the temperature control system were applied to the thermal denaturation and the trypsin digestion of protein. BSA(bovine serum albumin) was chosen for the test sample. It was successfully shown that BSA was successfully denatured at $75^{\circ}C$ for 1 min and digested by trypsin at $37^{\circ}C$ for 10 min.

      • SCIESCOPUSKCI등재

        Fabrication, Estimation and Trypsin Digestion Experiment of the Thermally Isolated Micro Teactor for Bio-chemical Reaction

        Tae Seok Sim,Dae Weon Kim,Eun-Mi Kim,Hwang Soo Joo,Kook-Nyung Lee,Byung Gee Kim,Yong Hyup Kim,Yong-Kweon Kim 대한전자공학회 2005 Journal of semiconductor technology and science Vol.5 No.3

        This paper describes design, fabrication, and application of the silicon based temperature controllable micro reactor. In order to achieve fast temperature variation and low energy consumption, reaction chamber of the micro reactor was thermally isolated by etching the highly conductive silicon around the reaction chamber. Compared with the model not having thermally isolated structure, the thermally isolated micro reactor showed enhanced thermal performances such as fast temperature variation and low energy consumption. The performance enhancements of the micro reactor due to etched holes were verified by thermal experiment and numerical analysis. Regarding to 42 percents reduction of the thermal mass achieved by the etched holes, approximately 4 times faster thermal variation and 5 times smaller energy consumption were acquired. The total size of the fabricated micro reactor was 37×30×1 ㎣. Microchannel and reaction chamber were formed on the silicon substrate. The openings of channel and chamber were covered by the glass substrate. The Pt electrodes for heater and sensor are fabricated on the backside of silicon substrate below the reaction chamber. The dimension of channel cross section was 200×100 ㎛². The volume of reaction chamber was 4 ㎕. The temperature of the micro reactor was controlled and measured simultaneously with NI DAQ PCI-MIO-16E-1 board and LabVIEW program. Finally, the fabricated micro reactor and the temperature control system were applied to the thermal denaturation and the trypsin digestion of protein. BSA(bovine serum albumin) was chosen for the test sample. It was successfully shown that BSA was successfully denatured at 75℃ for 1 min and digested by trypsin at 37℃ for 10 min.

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