조선소 용접작업자들의 총용접흄과 호흡성분진농도 비교연구

강용선,심상효,이송권,빈성오,최은석,Kang, Yong-Seon,Sim, Sang-Hyo,Lee, Song-Kwon,Bin, Sung-Oh,Choi, Eun-Seok 한국환경보건학회 2007 한국환경보건학회지 Vol.33 No.4

The purpose of this study is to assess the accurate state of the following: total welding fumes versus welding fumes in the air, respirable particulate mass, and exposure of dockyard welders to heavy metals. In addition, this study provides basic data for proposing improvements to create efficient and appropriate welding environments and to prevent occupational diseases. The subjects of this study were 94 laborers who worked at the block construction sites of large-scale dockyards located in Gyeongnam Province from March 2005 to June 2005. In order to collect samples on total welding fumes in the air and respirable particulate mass from the welders, Methods 0500 and 0600, established by the National Institute for Occupational Safety and Health (NIOSH), were used. The metals within the welding fumes were also analyzed using Inductively Coupled Plasma (ICP) under Method 7300 from NIOSH. The results of this research are summarized below. The geometric mean concentration of total welding fumes and that of respirable particulate mass were $4.11\;mg/m^3\;and\;3.53\;mg/m^3$, respectively. As a result of comparing the two measurement methods, there were significant differences (p<0.05) between the two groups for Ca, Cu, Cr, and Ni; however, there were no differences in Fe, Mg, Zn, Mg, Pb, and Cd. As a result of the analysis, the correlation between Mn and the concentration of heavy metals in the total welding fumes and respirable particulate mass was found to be -0.29, a significant negative correlation. The correlation between other heavy metals, however, was low. Finally, in the same total welding fumes, the correlation of Fe and Mg was high.

병원 도착 전 사망 환자의 사인기재에 관한 고찰

강용선,이경룡,박인철,조광현,김승호,이한식 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: To the emergency physician, issuing a death certificate is becoming a burden as the DOAs(Deaths on Arrival) have increased in recent years. We analyzed the agreement on the causes of death issued by emergency physicians and attempted to find out whether emergency physicians complied with the guidelines for issuing death certificates. Material & Method: A survey questionnaire containing twelve pre-selected DOA cases which were supplemented with relevant past medical history and physical examination was used. The cases, with varying causes of death, were chosen from the medical records of DOA patients who presented to the emergency department at Severance Hospital, Yonsei University College of Medicine, from January 1997 to December 2000. The questionnaires were sent to 60 emergency physicians(22 specialists and 38 residents) at 22 university-affiliated teaching hospitals and 2 general hospitals across the nation. They were asked to identify the most probable direct cause of death for each of the 12 cases. The same questionnaire was sent to medical examiners at the National Institute of Scientific Investigation and to a Korean emergency physician at Albert Einstein College of Medicine in New York, USA. We also included an open question about the optimal age for the use of 'senility' as a cause of death. Results: All 60 emergency physicians responded to the survey. The average number of causes of death per case was 9.7(7∼ 14). The range of concordance of causes of death was 23.3% to 66.6%. Out of a total of 720 causes of death given by the emergency physicians,35(4.9%) failed to adhere to the death certification guidelines, Also, 210 causes of death were not listed in the Korean classification of standard causes of death. Interestingly, the medical examiner answered 'unknown etiology' and the emergency physician in the USA answered 'cardiopulmonary arrest' or 'respiratory arrest' in most cases. Regarding 'senility' as a cause of death, 22 physicians(36.7%) thought the optimal age was over 80 years. Conclusion: A significant lack of agreement exists in determining the cause of death for the DOA patients arriving at emergency departments, Therefore, an all-out effort is essential to find ways to improve and resolve this situation. As the death certificate is a legal document and a basis for vital statistics, emergency physician should seek a rational consensus to improve and resolve these inconsistencies.

物價理論의 小考

姜容先 成均館大學校 商學會 1961 成均商學 Vol.2 No.1

조선업 용접작업장의 공기중 입자상물질 및 구성성분에 관한 연구

강용선 ( Yong Seon Kang ),신중규 ( Joong Kyu Shin ),이송권 ( Song Kwon Lee ),윤충식 ( Chung Sik Yoon ),임무혁 ( Moo Hyuk Lim ),박만철 ( Man Chul Park ),심상효 ( Sang Hyo Sim ) 한국산업위생학회 2007 한국산업보건학회지 Vol.17 No.3

This research was performed to evaluate the airborne personal concentration of hazardouse materials during the process of ship construction and surveyed from May 23 to June 30, 2007 in Kyungnam West Distirct, Korea. The subject was 94 ship construction workers exposed to welding fume and respirable particulate. The airborne concentrations of those were compared to Permissible Exposure Limit(PEL) from the Ministry of Labor in Korea. The airborne concentration of 23 samples(48.9%) of welding fumes was less than 5㎎/㎥, that of 16 (34.0%) was between 5 and 10㎎/㎥, and that of 8 (17.0%) was greater than 10㎎/㎥. The airborne concentration of 27 (57.4%) of respirable particulate masses was less than 5㎎/㎥ and the othere are greater than 5 ㎎/㎥. The welding fumes were identified containing the heavy metasl such as Fe, Mn, Zn, Mg, Ca, and Cu. The respirable particulates has similiar tendency with welding fumes in the component of heavy metals. But the concentration of Ca, Cu, Cr, and Ni turned out to be higher in welding fumes. Twenty (42.6%) of the 47 samples of welding fumes were exceeded PEL. In the heavy metals in welding fumes, ten (21.3%) of the 47 samples of Mn were exceeded PEL. Based on the results, the higher airborne hazardous materials were still exposed to wokers in ship construction process. It is suggested that the appropriate engineering control be applied to minimize the exposed cocnetration in ship building processes.

혈청 neuron specific enolase를 이용한 심정지후 신경학적 예후의 예측

강용선,정성필,박기일,김승환,김태승,이한식 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: The purpose of this study was to determine that the assessment of serum neuron specific enolase(NSE) could provide a reliable early predictor of neurologic outcome after cardiac arrest. Methods: Prospective, observational study was performed from April 1996 to March 1998 at a university teaching hospital ED. Serum NSE concentrations were analysed twice at 24 and 48 hours after return of spontaneous circulation(ROSC). Neurologic outcome was categorized using cerebral performance category(CPC). Results: Twenty-nine patients(16 were men) were enrolled during the study period. The mean age was 50.8 years. Nine(31%) of them showed good outcome defined as CPC 1-3, and 20(69%) patients showed bad outcome defined as CPC 4-5. In the good outcome group, the serum NSE was revealed 33.8±9.3 ng/ml at 24 hours, 34.0±4.73 ng/ml at 48 hours. While in the bad outcome group, it was 99.5±11.7 ng/ml and 114.6±15.8 ng/ml. The NSE at 48hr after ROSC was more prescise than that of 24hr. When the cutoff value of 50 ng/ml at 48hr, the sensitivity was 82%, and specificity was 93%. Conclusion: This study suggest that the serum NSE may represent a valuable, noninvasive, and useful clinical tool for prediction of neurologic outcome after cardiac arrest.

태권도 선수들의 상해에 관한 조사연구

강용선,조성초 군산대학교 체육과학연구소 2000 體育科學硏究所 論文集 Vol.2 No.-

The purpose of this study was to ivestigate the actual status and the causes of injuries of collegiate Taekwondo competitors. The questionnaire composed of 25 items was used as the research tool for this study. The respondents were 214 collegiate Taekwondo competitors(171 men and 43 women) who participated in the nationwide university Taekwondo championship tournaments early in 1999. Chi-square(X?) was used for the statistical procedures. An α=.05 probability level used for all tests of statistical significance. The results of this study were as follows: 1) More than 97% of respondents had experiences of the injuries related to Taekwondo, and Male competitors had more injury experiences than female competitors. 2) The injuries happened more frequency during practice than during competitions. 3) Both men and women were injured most frequently by the foot attack techniques, especially Front Turning Kick. 4) For both men and women, the most frequent injured part of the body was the leg, the second arm, the third face, the forth trunk, and the last head. The most frequent injured part of the leg was the knee for both men and women, that of the upper extremities was fingers for both men and women, and that of feet was ankles for men and top sides for women. 5) The 71.3 % of men and the 66.7 % of women with injured experiences continued to prantise or compete under the imperfect recovery from injuries. The 28% of men and The 33.5 % of women responded that there was not any expert for medical service at that time of injuries.

금속제품 제조 산업장내 공기중 금속농도에 관한 연구

김세동,강용선,구태형,윤형렬,문덕환,한용수 한국산업위생학회 1996 한국산업보건학회지 Vol.6 No.2

This study was conducted for the purpose of obtaining the fundamental data on improvement of working environment and contributing to health improvement of workers who dealed with metal by assessing the metal concentration in air of industries located in Chang-Won Industrial Complex. Authors measured the concentration of metals(Al, Cd, Cr, Cu, Mn, Ni, Pb, Sn and Zn) is the air to 25 working processes of 73 industries by flame atomic absorption spectrometry from February to December 1994. Personal air sampler was used for air sampling with mixed cellulose-ester membrane filter. The results were as follows : 1. The geometric means(range) of metal concentration; 1) Al: 0.1505 ㎎/㎥ (0.0147 - 18.6100 ㎎/㎥) 2) Cd: 0.0077 ㎎/㎥ (0.0003 - 7.0710 ㎎/㎥) 3) Cr: 0.0163 ㎎/㎥ (0.0013 - 1.1510 ㎎/㎥) 4) Cu: 0.0097 ㎎/㎥ (0.0009 - 0.4950 ㎎/㎥) 5) Mn: 0.0412 ㎎/㎥ (0.0006 - 4.7877 ㎎/㎥) 6) Ni: 0.0088 ㎎/㎥ (0.0001 - 1.0170 ㎎/㎥) 7) Pb: 0.0152 ㎎/㎥ (0.0015 - 0.4499 ㎎/㎥) 8) Sn: 0.0486 ㎎/㎥ (0.0037 - 0.1500 ㎎/㎥) 9) Zn: 0.1911 ㎎/㎥ (0.0122 - 8.2920 ㎎/㎥) 2. The geometric mean of lead exceeded TWA in assembling process of other general purpose machinery not elsewhere classified products manufacturing industries.

부하연결에 따른 비정질 실리콘박막 태양전지의 열화특성

박상현(Sang Hyun Park),강용선(Yong Sun Kang),조준식(Jun Sik Cho),이정철(Jung Chul Lee),윤경훈(Kyung Hun Yoou),송진수(Jin Soo Song) 한국태양에너지학회 2010 한국태양에너지학회 학술대회논문집 Vol.2010 No.11

수리조선 작업장에서의 공기중 석면 노출에 관한 연구

심상효,정희태,송기민,김윤신,강용선,Sim, Sang-Hyo,Chung, Hee-Tae,Song, Ki-Min,Kim, Yoon-Shin,Kang, Yong-Seon 한국환경보건학회 2008 한국환경보건학회지 Vol.34 No.4

This paper aims to provide basic data for work environment control, prevention of worker exposure to asbestos and improvement of air quality to protect workers ‘health after measuring the level of airborne asbestos and workers' exposure in a shipbuilding repair businesses. For this study, a total of 27 samples were collected from 27 workers who had been exposed to asbestos during engine, piping, boiler and other manufacturing processes in 'A' Shipbuilding Repair Company in Gyeongnam. This research was conducted from Oct. 1 to 30, 2007 and had the following results: The target group (27 workers) consisted of all men with an average age of 35.9 years and 6.6 years of work on average. Among them, fifteen 15 (55.6%) were smokers. In terms of their duties at work, there were 12 plumbing repair engineers (44.4%), 8 boiler repair engineers (29.6%) and 7 engine engineers (25.9%). The geometric mean concentration of airborne asbestos was 0.004 f/cc. A total of 4 samples exceeded the exposure limit. In particular, three exceeded the legal limit by more than double, which means that some workers have been highly exposed to asbestos. In terms of the concentration of asbestos fibres by work process, plumbing repair was the highest (0.0071 f/cc($0.001{\sim}0.57\;f/cc$)) while boiler was the lowest (0.0015 f/cc($0.001{\sim}0.007\;f/cc$)). Based on this study, proper action needs to be taken as soon as possible to protect workers from the threat of asbestos.

Quercetin, a Plant Polyphenol, Has Potential for the Prevention of Bone Destruction in Rheumatoid Arthritis

김해림,김보미,원지연,이경언,고현명,강용선,이상헌,김경운 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.2

We investigated the immune-regulatory function of quercetin, in interleukin (IL)-17-produced osteoclastogenesis in rheumatoid arthritis (RA). RA fibroblasts-like synoviocytes (RA-FLS) were stimulated with IL-17, and the mRNA expression and secretion of receptor activator of nuclear factor kappa-B ligand (RANKL) were detected by real-time polymerase chain reaction and enzyme-linked immunosorbent assay, respectively. CD14+ monocytes (osteoclast precursors) were stimulated with IL-17, RANKL, with/without quercetin, and tartrate-resistant acid phosphatase activity was evaluated to assess osteoclast differentiation. Osteoclast differentiation was investigated after coculturing IL-17-stimulated RA-FLS and Th17 cells with monocytes. CD4+ T cells were cocultured with quercetin under Th17-inducing conditions, and their differentiation to Th17 cells and Treg cells was determined by flow cytometry analysis. We found that IL-17 stimulated RA-FLS to produce RANKL and quercetin decreased the IL-17-induced RANKL protein levels. Quercetin decreased the IL-17-produced activation of mammalian target of rapamycin, extracellular signal-regulated kinase and inhibitor of kappa B-alpha. When monocytes were stimulated with IL-17, macrophage colony-stimulating factor or RANKL, mature osteoclasts were formed, and quercetin decreased this osteoclastogenesis. When monocytes were cultured with IL-17-prestimulated RA-FLS or Th17 cells, osteoclasts were produced, and quercetin decreased this osteoclast differentiation. In Th17-differentiation conditions, quercetin suppressed Th17 cell and the production of IL-17, but quercetin did not affect Treg cells. Quercetin inhibits IL-17-stimulated RANKL production in RA-FLS and IL-17-stimulated osteoclast formation. Quercetin reduces Th17 differentiation. Quercetin could be an additional therapeutic option for bone destructive processes in RA.