성남시 지역주민의 정신질환에 대한 태도 연구

고영,신수경,황태연,이충순,박연수,김인숙,황은숙,정원재 용인정신의학연구소 1999 용인정신의학보 Vol.6 No.1

노년기 치매와 우울증의 유병률 및 위험인자

서국희,김장규,연병길,박수경,유근영,양병국,김용식,조맹제 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.5

경기도 연천군에 거주하는 만 65세이상 노인 1,037명을 대상으로 1996년 12월부터 1997년 8월까지 9개월간에 걸쳐 치매와 노년기 우울장애의 유병률과 위험인자에 관한 이 단계 역학조사(일차선별검사후 이차 진단적 면접)를 수행하였다. 다단계 층화집락표본추출에 의한 확률표본법으로 대상자 선정을 하였고, 반응률은 85.2%이 었다. 일차선별검사에는 노인정신장애 평가척도 한국어판(K-PAS)을 사용하였고, 일상생활 능력척도(ADL) 및 수단적 일상생활 능력척도(IADL)를 사용하여 기능을 평가했고, 지지도 척도(APGAR)를 사용하여 사회적 지지정도를 평가하였다. 이차 진단적 면접에서는 진 신장애의 진단 및 통계편람 제3판 개정판(DSM-III-R)의 진단기준을 따라 임상 진단을 확정하였다. 감별진단 및 장애 정도의 평가를 위하여 보조적인 진단도구들을 사용하였다. 1) 연령 보정된 치매의 유병률(%)[95% 신뢰구간]은 6.83[6.12∼7.54](남자 6.34[5.29∼7.40], 여자7.09[6.14∼8.04]이었다. 이중 알쯔하이머형 치매의 유병률(%)[95% 신뢰구간]은 4.17[3.61∼4.74] (남자 2.42[1.76∼3.08], 여자 5.31[4.48∼6.14]이었고, 혈관성치매의 유별률(%)[95% 신뢰구간]은2.38[1.95∼2.81](남자 3.46[2.67∼4.25], 여자 1.63[1.16∼2.10])이었다. 2) 연령 보정된 우울장애의 유병률(%)[95% 신뢰구간]은 10.99[10.11∼11.87](남자 7.59[6.44∼8.73], 여자 13.46[12.20∼14.73])이었다. 진단별로는 주요 우울장애의 유병률(%)[95% 신뢰구간] 이 7.50[6.76∼8.26](남자 4.42[3.54∼5.31], 여자 9.78[8.68∼10.88]), 기분부전장애의 유병률(%)[95% 신뢰구간]이 2.02[1.62∼2.42](남자 1.37[0.86∼1.87], 여자 2.46[1.88∼3.03], 달리 특정되지 않은 우울장애 유병률 (%)[95% 신뢰구간]이 1.49[1.15∼1.83](남자 1.85[1.47∼2.23], 여자 1.28[0.96∼1.60])이었다. 3) 알쯔하이머형 치매의 통계적으로 유의한 5가지 위험인자는 85셍상의 고령(O.R.= 10.27), 무학(O.R.= 4.01), 흡연[흡연년수 0.1∼30년(O.R.= 3.11), 흡연년수 30년 이상 (O.R.= 4.60)], 알코올남용(O.R.= 2.98)과 치매의 가족력 (O.R.= 4.85)이었다. 4) 혈관성 치매의 통계적으로 유의한 3가지 위험인자는 '무학' (O.R.= 3.78), 흡연[40년 이상 흡연년수 (O.R.= 11.15)]과 '뇌졸중의 과거력 (O.R.= 26.76)'이었다. 5) 우울장애의 통계적으로 유의한 3가지 위험인자는 '75∼79세 연령군' (O.R.= 2.87), '뇌졸중의 과거력' (O.R.= 3.33)과 '우울장애의 가족력' (O.R.= 7.16)이었다. 중심단어:알쯔하이머형 치매·혈관성 치매·우울장애·유병률·위험인자·흡연. An epidemiological survey was conducted to estimate the prevalence of and identify the risk factors of dementia and depression in the elderly between December 1997 and August 1998 in Yonchon County, Korea. A total of 1,037 elderly aged 65 years and over underwent a two phase diagnocstc procedure. Multiple stage, random cluster sampling method was used to select the subjects. Response rate was 85.4%. For the Ist stage screening survey, the Korean Psych-ogeriatric Assessment Scale was used as a primary screening tool, which had already been standardized in Korea, and functioning and social support were assessed by ADL, IADL and APGAR. At the 2nd stage, diagnoses were confirmed according to the DSM-Ⅲ-R. And several other scales were used as supporting information for differential diagnoses and for evaluating severity. 1) Age-sex adjusted prevalence(%)[95% C.I] of dementia was 6.83[6.12-7.54](male 6.34 [5.29-7.40], female 7.09[6.14-8.04]). Prevalence of the dementia of the Alzheimer's type was 4.17[3.61-4.74](male 2.42[1.76-3.08], female 5.31[4.48-6.14]) and that of the va-scular dementia was 2.38[1.95-2.81](male 3.46[2.67-4.25],female 1.63[1.16-2.10]). 2) Age-sex adjusted prevalence(%)[95% C.I.] of depressive disorder was 10.99[10.11-11.87](male 7.59[6.44-8.73], female 1346[12.20-14.73]. Among depressive disorders, prev-alence(%)[95% C.I.] of major depressive disorder was 7.50[6.76-8.26](male 4.42[3.54-5.31], female 9.78[8.68-10.88]), that of dysthymic disorder was 2.02[1.62-2.42](male 1.37[0.86-1.87], female 2.46[1.88-3.03]) and that of depressive disorder NOS was 1.49[1.15-1.83](male 1.85[1.47-2.23], female 1.28[0.96-1.60]). 3) Five statistically significant risk factors of the dementia of the Alzheimer's type were identified : age over 85(O.R. = 10.27), illiteracy (O.R. = 4.01), alcohol abuse (O.R. = 2.98), smoking [0 < pack year ≤30(O.R. = 3.11), pack year>30(O.R. = 4.60)] and family history of dementia (O.R. = 4.85). 4) Three statistically significant risk factors of the vascular dementia were identified : illiteracy (O.R. = 3.78), history of CVA(O.R. = 26.76) and smoking over 40 pack year(O.R. = 11.15). 5) Three statistically significant risk factors of the depressive disorder were identifed : age between 75 and 79(O.R. = 2.87), past history of CVA(O.R. = 3.33) and family history of depressive disorder(O.R. = 7.16). KEY WORDS:Dementia of the Alzheimer's Type·Vascular dementia·Depressive disorder·Prevalence·Risk factor·Smoking.

Case Reports : Laparoscopic management of pelvic splenosis

( Sue Yeon Park ),( Ji Ye Kim ),( Jung Hun Lee ),( Joong Sub Choi ),( Jung Hwa Ko ),( Seon Hye Park ) 대한산부인과학회 2014 Obstetrics & Gynecology Science Vol.57 No.1

Splenosis is defined as heterotopic autotransplantation of spleen tissue following traumatic rupture of the spleen, or surgery. It is a benign disease that is generally without any symptoms and is discovered incidentally. Surgical intervention is recommended if symptoms are present. We report the successful laparoscopic management of a 49-year-old Korean woman with splenosis-associated symptoms who had undergone splenectomy.

Film Session Q&A 1 : Laparoscopically assisted staging surgery for Korean Woman with Endometrial cancer

( Sue Yeon Park ),( Jung Hun Lee ),( Jung Hwa Ko ),( Joong Sub Choi ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

Endometrial cancer is the most common gynaecologic cancer and the third most frequent gynaecologic cancer in Korea, followed by cervical cancer and ovarian cancer. The incidence of endometrial cancer has gradually increased in Korea. Endometrial cancer surgeries have been traditionally performed via laparotomy to accomplish a total abdominal hysterectomy (TAH) and surgical staging of retroperitoneal lymph nodes. Childers et al were the first authors to report the use of laparoscopically assisted vaginal hysterectomy (LAVH) with laparoscopic staging of pelvic and para-aortic lymph nodes in 1992 for treatment of early-stage endometrial cancer. Since that time, numerous reports have supported the equivalency of laparoscopic nodal staging compared with traditional open surgical staging for endometrial cancer. This video clip shows the procedure of the laparoscopically assisted staging surgery (LASS) including peritoneal washing cytology, LAVH with bilateral salpingo-oophorectomy, pelvic and para-aortic lymphadenectomy. LASS can be performed without additional morbidity and complications, and might be feasible in Korean women with endometrial cancer.

Single port laparoscopic surgery reduces postoperative pain in women with benign gynecologic disease, really?

( Sue Yeon Park ),( Jeong Min Eom ),( Jung Hwa Ko ),( Joong Sub Choi ),( Jung Hun Lee ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

The primary objective of this study is to compare postoperative pain between women underwent single port laparoscopic surgery (SP-LS group) or conventional-laparoscopic surgery (conventional-LS group). The secondary objective is to evaluate the difference of postoperative pain between SP-LS group and conventional-LS group according to whether or not hysterectomy has been performed This prospective case-control study was performed at University teaching hospital. For postoperative pain, a total of 399 women were enrolled and of these 116 were in the SP-LS group and 283 in the conventional LS group. We evaluated the pain score, number of patients administered of intravenous or intramuscular pain medication, and number of patients with nausea or vomiting at 2, 4, 6, 12, 24, 48 and 72 hours after surgery Clinical characteristics and operative outcomes were similar in both groups. The postoperative pain score except for the time of postoperative 2 hours after was similar in both groups. According to the type of operation, SP-LS reduced postoperative pain in the group of SP-LS not including laparoscopically assisted vaginal hysterectomy (LAVH). SP-LS didn`t provide significant advantage compared with conventional LS in terms of postoperative pain. But SP-LS reduced pain on postoperative 2 hours after and when performed not including LAVH. To confirm these results, additional large, randomized trials more specifically controlled are needed.

Ground Beetle Assemblage (Coleoptera: Carabidae) along Altitudinal Gradient in Mt. Sobaeksan

Jong Kook Jung,Seung Tae Kim,Sue Yeon Lee,Jong Kyun Park,Joon Ho Lee 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.10

This study was conducted to investigate the altitudinal distribution of the ground beetle community in a mountain area during 2007 to 2009, and to examine what habitat characters are most relevant to the distribution of mountain ground beetle species, and finally to identify potential biological indicators for monitoring in forest. The study area was Mt. Sobaeksan National Park (1439 m elevation), in Punggi-up, Gyeongsangbuk-do, Korea. Ground beetles were collected by pitfall traps, which were installed along the altitudinal gradient 437, 757, 1100 and 1420 m. In total, 3,259 individuals were identified as 32 species in 18 genera. The dominant species were Synuchus cycloderus (29.4%), Eucarabus sternbergi sobaeksanensis (15.4%) and Pterostichus orientalis (9.7%) in order. Overall, the ground beetle community structure was different along the altitude (similarity 65.2%) by NMDS ordination, but also were clustered into 2 groups, 437 and 757 m, and 1100 and 1420 m (similarity 57.9%). Therefore, the ground beetle assemblage could provide basic information for forest management. In this study, some ground beetle species were suggested to potential biological indicators along altitudinal gradient.

Improved in vitro developmental competence of porcine embryos with citrate supplement in culture medium.

Park, Seon-Mi,Jang, Goo,Hossein, Mohammad Shamim,Lee, So-Hyun,Jeong, Yeon-Woo,Kim, Sue,Kim, Ji-Hye,Hashem, Mohammad Abul,Koo, Ok-Jae,Lee, Eu-Gene,Lee, Byeong-Chun,Hwang, Woo-Suk 한국수정란이식학회 2005 한국수정란이식학회 학술대회 Vol.2005 No.1

정신분열병 가계에서 6p24-22 염색체에 대한 연관 분석

박동연,이유상,장용이,조은영,전현옥,박해정,김종원,김창현,이동수,홍경수 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5

Objectives : Chromosome 6p24-22 has been identified as a disease locus with a high probability for schizophrenia based on several genomewide linkage scans with Caucasian families. The recent association studies suggest that the dysbindin gene located at chromosome 6p22.3 may be a candidate gene of schizophrenia. The purpose of this study was to investigate the linkage of chromosome 6p24.3-22.3 locus to schizophrenia in Korean families. Methods : We recruited one hundred fifty-seven family members from forty-six multiplex schizophrenia families. One hundred three of them were affected individuals. four microsatellite markers with 4.8 cM intervals on 6p24.3-22.3 were genotyped. Non-parametric linkage analysis was performed by evaluating the levels of allele sharing between the affected relative pairs. Results : In the single point analysis, no markers on chromosome 6p24.3-22.3 locus showed statistical evidence for linkage. Significant evidence for linkage was not found in the multi-point analysis. Conclusion : These results do not support the previous evidence from Caucasian families for a locus predisposing to Schizophrenia at 6p24.3-22.3, the locus of dysbindin gene. We conclude that if there is a susceptibility locus for schizophrenia in this region then its effect size is so small as to render our study insufficiently powerful to detect it and schizophrenia susceptibility loci in Korean families likey have different ethnicity-specific effects from Caucasian families.

정신분열병에서 결핍증후군의 진단적 안정성 평가 : 5년간 추적 조사 A 5-year Follow-up Study

박동연,최경숙,이동수,홍경수 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.3

pH Triggered Switching Dye Sensor Based on Furan and Pyrone Units

Park, Jung-Young,Lee, Sue-Yeon,Gwon, Seon-Yeong,Yoon, Nam-Sik,Son, Young-A,Kim, Sung-Hoon 한국섬유공학회 2012 FIBERS AND POLYMERS Vol.13 No.2

pH triggered dye sensor based on pyrone unit as a donor group and furan unit as an acceptor grouphave resulted in very promising optical switches, when dye was applied by alkali-induced nucleophilic additionreaction. The dye displayedclear UV-Visible absorption changes and new fluorescence emission behaviors, which are based on intramolecular charge transfer (ICT) system of the dye molecular structure. The levels of energy potential and the electron density distributions of this dye chemosensor were also simulated and discussed using computational modelcalculation.