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송이 (Tricholoma matsutake) 자실체의 화학성분
이학주,최윤정,가강현,박원철 한국목재공학회 2003 목재공학 Vol.31 No.4
송이(Tricholoma matsutake) 자실체의 메탄올(methanol, MeOH) 추출물로부터 4개의 화합물을 분리하였으며, 기기분석 결과 adcnosinc (9-β-D-ribofuranosyladenine)을 비롯하여, methyl trans-cinnamate, ergosterol (ergosta-5, 7, 22-triene-3β-ol) 및 ergosta-4, 6, 8 (14), 22-tetraen-3-one으로 각각 동정하였다. One alkaloid derivatives, one amide and two steroids were isolated from the fruit bodies of Tricholoma matsutake. The structures were determinded as adenosine, methyl trans-cinnamate, ergosterol and ergosta-4, 6, 8 (14), 22-tetraen-3-one, respectively, on the basis of spectroscopic data.
소목(Caesalpinia sappan) 추출물의 Streptococcus mutans에 대한 성장, 산생성, 부착 및 비수용성 글루칸 합성 억제에 미치는 영향
유용욱,유현희,김윤정,유미선,서세정,이황,이흥수 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.2
Streptococcus mutans is known as the causative bacterial playing the most important role in forming plaque and it is being noticed as major causative bacteria of dental caries. Therefore, development of more effective, substantial and safe preventive agent against dental caries and periodontal disease is honestly required. The present study was designed to investigate the effect of chloroform extract(CE), n-butanol extract(BE),methanol extract(ME) and water extract(WE) of Caesalpinia on the growth, acid production, adhesion, and insoluble glucan synthesis of Streptococcus mutans. The CE, BE, ME and WE decreased the growth and acid production of S.mutans than that of control, especially, the ME was more effective than other extracts. The effect of CE, BE, ME and WE on the adherences to saliva-coated hydroxyapatite bead(S-HA) were evaluated. At the concentration of 2,000 ㎍/㎖, the CE showed 32% rate of bacterial adherence to S-HA, whereas, other extracts of the same concentration producedgreater than 50% rate. The CE and BE were significantly decreased the reduction rates of water insoluble glucan formation from sucrose by crude glucosyltransferase of S.mutans. Thus, the application of C. sappan can be considered a useful and a practical method for the prevention of dental caries.
그리기 활동을 통한 초등학생들의 환경에 대한 인식 분석
위수민,이승철,김윤지,김현정 韓國敎員大學校 敎育硏究院 2008 敎員敎育 Vol.24 No.2
이 연구는 초등학교 6학년 학생의 환경 인식은 어떤 특징을 가지고 있으며,학생이 생활하는 지역에 따라 환경 인식은 어떤 차이가 있는지를 알아보고자 하였다. 광주광역시와 경기도에 위치한 5개교 10학급 340명을 대상으로 환경에 대한 그리기 활동과 그림에 대한 설명 그리고 그림에 등장하는 환경 요소를 분석하여 학생들의 환경 인식을 확인하였다. 연구 결과,환경에 대한 인식은 인공 환경,자연 환경,인간 공존 환경,추상적 환경으로 표면화 되었으며,생물과 무생물 및 인공물을 포함한 다양한 환경 요소들올 표현하여 학생들의 일상적인 생활 주변의 환경 요소에 대한 높은 인식이 드러난 것으로 보인 다. 5 유형으로 구분한 거주 지역별 학생들이 갖는 환경 인식은 유의미한 차이를 보이지 않았고 인공 환경으로 인식하는 경우가 일반적이었다. The present study purposed to examine the charactehstics of sixth-graders'perception of the environment and difference in their perception of the environment according to area. For this study, we surveyed the perception of the environment in 10 classes 340 students from 5 elementary schools in Gwangju and Gyeonggi do by analyzing their environment related drawing activities, their explanations about their drawings, and environmental elements appearing in the drawings. According to the results of this study, sixth-graders'perception of the environment were described by artificial environment, natural environment, environment in which people live together, and abstract perceptions. In addition, they expressed various environmental elements such as living things, lifeless things and artificial things, and this shows their high perception of environmental elements around them. What is more, the sixth-graders from five different areas did not show any statistically significant difference in their perception of the environment, but perception as artificial environment was more general among the students.
한국인 간세포암 환자에서 경피적 에탄올 주입술의 치료 효과
강현우 ( Kang Hyeon U ),김윤준 ( Kim Yun Jun ),김강모 ( Kim Gang Mo ),강정묵 ( Kang Jeong Mug ),김수환 ( Kim Su Hwan ),김진현 ( Kim Jin Hyeon ),윤원재 ( Yun Won Jae ),윤정환 ( Yun Jeong Hwan ),윤용범 ( Yun Yong Beom ),이효석 ( Lee 대한소화기학회 2003 대한소화기학회지 Vol.42 No.6
Background/Aims: Percutaneous ethanol injection therapy (PEIT) is widely used for the treatment of hepatocellular carcinoma (HCC). However, its long-term therapeutic efficacy is not verified in Korea, one of hepatitis B virus (HBV) endemic areas. Thus, this study was to assess its efficacy and prognostic factors affecting tumor-free survival following PEIT in Korean HCC patients. Methods: From 1997 to 1999, 100 consecutive patients who had 1 to 3 HCC nodules of maximum diameter less than 3 cm and underwent PEIT were enrolled. Therapeutic efficacy, overall and tumor-free survival rates were assessed during follow-up periods. Results: In 83 patients, HCC nodules were completely ablated by PEIT. The cumulative 1, 2, and 3 year overall survival rates were 98%, 96%, and 88%, respectively. The cumulative 1, 2, and 3 year tumor-free survival rates were 73%, 50%, and 37%, respectively. Larger tumors (=2 cm) were associated with a higher local recurrence rate. Conclusions: These results demonstrate that PEIT is therapeutically useful in patients with HCC less than 4 in number and less than 3 cm in diameter. However, since multiple or large tumors are associated with low tumor-free survival or high local recurrence rates, PEIT for these tumors and the subsequent post-treatment follow-up should be performed carefully. (Korean J Gastroenterol 2003;42:502-509)
Metal–Insulator–Semiconductor Diode Consisting of Two-Dimensional Nanomaterials
Jeong, Hyun,Oh, Hye Min,Bang, Seungho,Jeong, Hyeon Jun,An, Sung-Jin,Han, Gang Hee,Kim, Hyun,Yun, Seok Joon,Kim, Ki Kang,Park, Jin Cheol,Lee, Young Hee,Lerondel, Gilles,Jeong, Mun Seok American Chemical Society 2016 NANO LETTERS Vol.16 No.3
<P>We present a novel metal-insulator-semiconductor (MIS) diode consisting of graphene, hexagonal BN, and monolayer MoS2 for application in ultrathin nano electronics. The MIS heterojunction structure was fabricated by vertically stacking layered materials using a simple wet chemical transfer method. The stacking of each layer was confirmed by confocal scanning Raman spectroscopy and device performance was evaluated using current versus voltage (I-V) and photocurrent measurements. We clearly observed better current rectification and much higher current flow in the MIS diode than in the p-n junction and the metal-semiconductor diodes made of layered materials. The I-V characteristic curve of the MIS diode indicates that current flows mainly across interfaces as a result of carrier tunneling. Moreover, we observed considerably high photocurrent from the MIS diode under visible light illumination.</P>
A Case of Idiopathic Aortitis with Left Renal Vein Thrombosis
Hyeon Jeong Yun,Jin Uk Jeong,Jong Ho Shin,Jin Ho Choi,Young Min Na,Jin Cheol Myeong,Ki Tae Bang 순천향대학교 순천향의학연구소 2014 Journal of Soonchunhyang Medical Science Vol.20 No.2
A 38-year-old man was admitted to the hospital because of abrupt left flank pain. He had no fever and physical examination revealed tenderness of the left costovertebral angle. Laboratory data revealed white blood cell 16,060/μL, C-reactive protein 0.93 mg/ dL. Urinalysis showed more than 1/2 red cells per high-power field with severe proteinuria (4+). Enhanced computed tomography (CT) showed the thickened abdominal aorta wall with partial thrombus. The thickened aorta wall compressed the left renal vein and it caused left renal vein thrombosis. Abdominal CT findings suggested aortitis of the abdominal aorta with complication of left renal vein. We could exclude other types of aortitis including autoimmune aortitis, Takayasu’s arteritis, giant cell arteritis, and infectious causes based on a serologic test and the history of the patient. Therefore, the patient was diagnosed with idiopathic aortitis and treated with glucocorticoid. After treatment, his symptoms disappeared and a follow-up CT showed decreased mural thickening of the abdominal aorta. Isolated idiopathic aortitis presented with renal vein thrombosis is extremely rare and has not been reported in Korea yet. We present a rare case report on idiopathic aortitis of the abdominal aorta with complication of left renal vein thrombosis.
Jeong Hyunjin,Hong Eun-Hye,Ahn Jae-Hee,Cho Jaewon,Jeong Jae-Hyeon,Kim Chae-Won,Yoon Byung-Il,Koo Ja Hyun,Park Yun-Yong,Yang Yoon Mee,Iwawaki Takao,Bruce A. Vallance,Chang Sun-Young,Ko Hyun-Jeong 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Endoplasmic reticulum stress is closely associated with the onset and progression of inflammatory bowel disease. ERdj5 is an endoplasmic reticulum-resident protein disulfide reductase that mediates the cleavage and degradation of misfolded proteins. Although ERdj5 expression is significantly higher in the colonic tissues of patients with inflammatory bowel disease than in healthy controls, its role in inflammatory bowel disease has not yet been reported. In the current study, we used ERdj5-knockout mice to investigate the potential roles of ERdj5 in inflammatory bowel disease. ERdj5 deficiency causes severe inflammation in mouse colitis models and weakens gut barrier function by increasing NF-κB-mediated inflammation. ERdj5 may not be indispensable for goblet cell function under steady-state conditions, but its deficiency induces goblet cell apoptosis under inflammatory conditions. Treatment of ERdj5-knockout mice with the chemical chaperone ursodeoxycholic acid ameliorated severe colitis by reducing endoplasmic reticulum stress. These findings highlight the important role of ERdj5 in preserving goblet cell viability and function by resolving endoplasmic reticulum stress.
Process Optimization for Preparing High Performance PAN-based Carbon Fibers
Yun, Jeong-Hyeon,Kim, Bo-Hye,Yang, Kap-Seung,Bang, Yun-Hyuk,Kim, Sung-Ryong,Woo, Hee-Gweon Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.10
wet spun polyacrylonitrile (PAN) fiber precursors. The process variables chosen were treatment temperature, applied tension in stabilization process. The temperature profile of the stabilization was set on the basis of exothermic peaks of the differential scanning calorimetry (DSC) result. Both tensile strength and modulus increased with holding at onset temperatures of the exothermic peaks for extended duration, and with a higher heating rate up to the onset temperatures at a given applied tension among the experimental conditions. The increase in load monotonously increased the tensile modulus, on the other hand, the tensile strength was maximum at the load of 15 mg/filament (T15). The load 20 mg/ filament (T20) was considered to be exceeded to form oriented crystalline structure, possibly introducing more defects in the fiber than under load of T15. The sample CP3-T15 O5 H30 showed the best tensile properties among the samples experimented whose tensile properties are compatible with the commercialized grade of general purpose carbon fibers even at low carbonization temperature such as $800\;{^{\circ}C}$ (the carbonization temperature in the commercial process. 1300∼$1500\;{^{\circ}C}$).