在日韓國人의 生活文化의 異質化와 適應過程에 關한 保健學的 硏究

金正根(Jong-Kun Kim),張昌谷(Chang-Gok Chang),林達旿(Dar-Oh Lim),金武采(Mu-Chae Kim),李州烈(Ju-Yul Lee) 한국인구학회 1992 한국인구학 Vol.15 No.2

After world war Ⅱ Japanese life expectancy has been improved remarkably, and reached the highest level in the world around late 1970's. The life expectancy of Korean has also shown tremendous improvement in recent years with about 20 year's gap from the Japanese. The reason of rapid improvement of life expectancy can be explained by changes in the structure of cause of death due to health system, living standard, social welfare, health behavior of individuals and so on. Korean in Japan is placed under different situations from both Korean in Korea and Japanese in these regards, and expected to show different picture of cause of death pattern. The objective of this study is the comparision of changing patterns of cause of death of three population groups, Korean in Japan, Korean in Korea and Japanese, and to investigate the reasons which effect to the structural difference of mortality cause with special emphasis on health ecological aspects. One of the major limitations of the Korean causes of death statistics is the under-registration which ranges about 10% of the total events, and inaccuracy of the exact cause of death. Some 20% of registered deaths were unable to classify by ICD. However, it is concluded that the Korean data are evaluated as sufficient to stand for over-viewing of trends of cause of death pattern. The evaluation is done by comparing data from registration and field survey over the same population sample. Population data of Korean in Japan differ between two sources of data; census and foreigner's registration. Correction is done by life table method under the assumption that age-specific mortality pattern would accord with that of the Japanese. The crude death rate was lowest among Korean in Japan, 5.7 deaths per 1,000 population in 1965. The crude death rates of Korean in Japan and Japanese are increasing recently influenced by age structure while Korean in Korea still shows decreasing tendency. The adjusted death rate is lowest among Japnaese, followed by Korean in Japan, and Korean in Korea. The leading causes of death of Korean in Korea until 1960's was infectious diseases including pneumonia and tuberculosis. The causes of death structure changed gradually to accidents, neoplasm, hypertensive disease, cerebro-vascular disease in order. The main difference in cause of death between Korean and Japanese is high rate of liver diseases and diabetes for both Korean in Japan and Korea. A special feature of cause of death among Korean in Korea is remakably high rate of hypertensive disease, which is assumed to be caused by physicians tendency in choosing diagnostic categories. The low ischemic heart disease and high vasculo-cerebral disease are the distinctive characteristic of the three population groups compared to western countries. Specific causes of death were selected for detailed sex, age and ethnic group comparisons based on their high death rates. Cancer is the cause of death which showed most drama tical increase in all three population groups. In Korea 20.1% of all death were caused by cancer in 1990 compared with 10.5% in 1981. Cancer of the liver is the leading cause of cancer death among Korean in Japan for both sexes, followed by cancer of the lung and cancer of the stomach, while that of Korean in Korea is cancer of the stomach, followed by cancer of the liver and cancer of the lung for male. Causes of infant mortality were examined among the three population groups since 1980 on yearly bases. For both Japanese and Korean in Japan, leading cause of death ranks as conditions originating in the perinatal period, congenital anomalies, accidents and other violent causes. Trends since 1980 for these two population groups in the leading cause of infant mortality showed no changes. On the contrary, significant changes in leading cause of death structure in Korea were observed : The ranking of leading cause of death in 1981 were congenital asnomali

최적 연료주입 모델 추종형 ${\mu}-$합성 제어기의 설계에 관한 연구

황현준,김동완,정호성,손무헌,김영훈,황기현,문경준,박준호,황창선,Hwang, Hyun-Joon,Kim, Dong-Wan,Jeong, Ho-Seong,Son, Mu-Hun,Kim, Yeung-Hun,Hwang, Gi-Hyun,Mun, Kyeong-Jun,Park, June-ho,Hwang, Chang-Sun 제어·로봇·시스템학회 1998 제어·로봇·시스템학회 논문지 Vol.4 No.2

In this paper, we design an optimal model following ${\mu}-$synthesis control system for fuel-injection of diesel engine which has robust performance and satisfactory command tracking performance in spite of uncertainties of the system. To do this, we give gain and dynamics parameters to the weighting functions and apply genetic algorithm with reference model to the optimal determination of the weighting functions that are given by the D-K iteration method which can design ${\mu}-$synthesis controller in the state space. These weighting functions are optimized simultaneously in the search domain which guarantees the robust performance of the system. The ${\mu}-$synthesis control system for fuel-injection designed by the above method has not only the robust performance but also a better command tracking performance than those of the ${\mu}-$synthesis control system designed by trial-and-error method. The effectiveness of this ${\mu}-$synthesis control system for fuel-injection is verified by computer simulation.

Curcumin ameliorates cadmium-induced nephrotoxicity in Sprague-Dawley rats

Kim, Kyeong Seok,Lim, Hyun-Jung,Lim, Jong Seung,Son, Ji Yeon,Lee, Jaewon,Lee, Byung Mu,Chang, Seung-Cheol,Kim, Hyung Sik Elsevier 2018 Food and chemical toxicology Vol.114 No.-

<P><B>Abstract</B></P> <P>Chronic exposure to cadmium (Cd) causes remarkable damage to the kidneys, a target organ of accumulated Cd after oral administration. The aim of the present study was to investigate the protective effect of curcumin against Cd-induced nephrotoxicity. Sprague–Dawley male rats were divided into the following four treatment groups: control, curcumin (50 mg/kg, oral), CdCl<SUB>2</SUB>, (25 mg/kg, oral), and pre-treatment with curcumin (50 mg/kg) 1 h prior to the administration of CdCl<SUB>2</SUB> (25 mg/kg, oral) for 7 days. At 24 h after the final treatment, the animals were killed, and the biomarkers associated with nephrotoxicity were measured. Our data indicated that blood urea nitrogen (BUN) and serum creatinine (sCr) levels were significantly reduced by curcumin pre-treatment in CdCl<SUB>2</SUB>-treated animals. Histopathological studies showed hydropic swelling and hypertrophy of the proximal tubular cells in the renal cortex after Cd treatment. Pretreatment with curcumin ameliorated the histological alterations induced by Cd. The urinary excretion of kidney injury molecule-1 (Kim-1), osteopontin (OPN), tissue inhibitor of metalloproteinases 1 (TIMP-1), neutrophil gelatinase-associated lipocalin (NGAL), and netrin-1 significantly reduced by curcumin treatment compared to that in the CdCl<SUB>2</SUB>-treated group. The administration of curcumin provided a significant protective effect against Cd-induced nephrotoxicity.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Curcumin protects against cadmium-induced renal injury. </LI> <LI> Curcumin reduces urinary excretion of AKI biomarkers. </LI> <LI> Curcumin protects against cadmium-induced apoptosis in the kidney. </LI> </UL> </P>

유비쿼터스 환경을 위한 CASA 기반의 동적 접근 제어 기법

김경자(Kim Kyoung Ja),장태무(Chang Tae Mu) 한국컴퓨터정보학회 2008 韓國컴퓨터情報學會論文誌 Vol.13 No.4

기존의 상황 인식 서비스 모델에서는 리소스에 대한 접근 권한을 사용자의 인증으로만 리소스에 대한 접근을 허용하였으나, 사용자의 주변 상황 정보가 빈번하게 변화하는 유비쿼터스 환경에서는 상황 변화에 따른 리소스 접근제어가 제공될 필요가 있다. 본 논문에서는 사용자의 상황 정보가 변경되는 경우에 따라 리소스에 대한 접근 권한을 동적으로 제어하고자 한다. 접근 제어는 기존의 CASA(Context-Aware Security Architecture)를 기반으로 하지만 현재 서비스를 받고 있는 사용자라 할지라도 리소스 접근 권한을 제한할 수도 있다. 즉, 주위 환경 정보를 실시간으로 검사하여 주위 환경에 따라 동적으로 접근 권한을 달리 부여하여 기존의 상황 인식 서비스보다 리소스에 대한 강인한 보안 서비스를 제공한다. Conventional context-aware service models permit the access of resources only by user authentication, but the ubiquitous environments where the context information around users is changing frequently require the resource access control according to the rapid changes. This paper proposes a scheme to control access permission of resource dynamically as context information of user changes. Our access control model is based on traditional CASA (Context-Aware Security Architecture), but can restrict the access of the user already has been authorized. With the real-time checking of context information, our scheme gives different access controls according to changes in environmental information, and provides more secure services than conventional context-aware models.

자율주행 자동차의 상용화가 상업 공간구조에 미치는 영향

서현승 ( Seo Hyun-seong ),김민준 ( Kim Min-jun ),정창무 ( Jung Chang-mu ),김현정 ( Kim Hyunjung ) 한국부동산분석학회 2020 不動産學硏究 Vol.26 No.4

본 논문은 자율주행 자동차 상용화와에 따른 전국 상업 공간 구조에 미치는 영향에 대해 연구하고자 한다. 자율주행 자동차의 출현은 도시에 극적인 변화를 가져올 것으로 예상된다. 그러나 최근의 연구는 국토 공간구조의 가능한 변화 추정이 아닌, 주로 차량 기술에 초점을 맞추고 있다. 이러한 배경에서 본 연구는 일련의 시나리오를 개발하고, 자율주행 자동차로 인한 편익 발생 모델을 구축하고, 자율주행 자동차 사용으로 인한 소득 증가로 인해 국토 공간구조의 변화를 분석하는 것을 목표로 한다. 문헌 검토를 기반으로 네 가지 시나리오를 설정하였으며, 시나리오 별 자율주행 자동차의 상용화 정도를 예측하기 위해 주요 요소의 계수를 포함한다. 각 시나리오 별 편익 계산한 것을 바탕으로 상권의 소득 및 직원 증가에 따른 전국 상업 공간 구조의 변화를 제시한다. 본 논문의 시뮬레이션 결과 자율주행 자동차가 초기 단계에서는 특정 지역에만 분포되어 있기 때문에 상업 연면적 증가량의 지역적 격차가 증가하는 것을 보여준다. 하지만 자율주행 자동차 보급률이 증가함에 따라 전국적으로 상권의 매출, 고용자 수 증가로 교외 지역도 발달하여 지역 불균형 개발이 감소한다. 장기적으로 시간이 지남에 따라 지역적 격차가 줄어들고 국토의 균형적 개발이 가능할 것으로 예상된다. This paper aims to investigate the relationship between commercialization of autonomous vehicles and its influence on commercial spatial structures nationwide. The emergence of autonomous vehicles is expected to bring about dramatic changes in our cities. However, recent studies mainly focus on the technology of vehicles, not the estimation of possible changes. For this reason, our study aims to develop a set of scenarios, build forecasting model for benefits of autonomous cars, and analyze the changes in territory due to the increased income from using autonomous vehicles. Four different scenarios have been identified based on literature review, containing different coefficients of the main elements for forecasting future commercialization of autonomous vehicles. From the benefits we concluded in each scenarios, which were calculated through main elements, we propose the change in commercial spatial structures nationwide due to the increased income and employee. Our simulation results show that in the early stage, regional gap increases since autonomous vehicles are only distributed in specific area. However, as autonomous vehicles’ dissemination rate increases, suburban area also develop due to increasement in revenue and number of employee, leading to reducement in territory unbalanced development. Regional gap decreases as time passes and territory balanced development increases in the long run.

대용특성을 이용한 측정시스템 분석

김주환,장무성,김상부 國立 昌原大學校 產業技術硏究院 2004 産技硏論文集 Vol.18 No.-

Since 1996, many Korean companies such as Samsung, LG, Hyundai Motor Company, have adopted Six Sigma in order to get a competitive edge in the global marketplace. There are, however, many problems to be solved for successfully implementing Six Sigma in an organization. As is known, one of the key principles of Six Sigma is a data-based management or a decision making based on data. Therefore, Six Sigma requires more measurement than ever, which makes measurement system analysis more important. Usually, a gage R&R study is performed to identify the measurement system's variation relative to process variation. In the study, a gage R&R study is considered for the case where measuring a major quality characteristic accompanies a destructive testing. We suggest a gage R&R study using a screening variable that is highly correlated with the major quality characteristic and also can be measured by a nondestructive testing method. It is assumed that the major quality characteristic and a screening variable have a bivariate normal distribution. A simulation study on the proposed method is performed and we compare it with the conventional gage R&R study for a destructive testing.

임실관촌 사선대 일대의 식물상과 분포

길봉섭,김창환,김무열,이은복 원광대학교 생명공학연구소 1997 생명공학연구소보 Vol.5 No.1

임실 관촌 사선대의 관속식물은 66과 145속 177종 1아종 20변종 4품종으로 총 202종류가 분포하고 있는 것으로 조사되었다. 조사기간이 가을 한 철에 불과했던 사정을 감안한다면 이보다 더 많은 종류가 있을 것이 확실하다. 사선대의 식물군락은 식물사회학적인 방법으로 분류한 결과 목본은 졸참나무군락(Quercus serrata community), 가침박달군락(Exochorda serratifolia community), 개서어나무군락(Carpinus tschonoskii community), 느티나무군락(Zelkova sarrata community), 상수리나무군락(Quercus acutissima community), 갈참나무군락(Quercus aliena community), 긴산개나리군락(Forsythia saxatilis var. lanceolata community) 그리고 리기다소나무식재림(Pinus rigida plantation) 등으로 구분되었고, 초본은 복수초군락(Adonis amurensis community), 피나물군락(Hylomecon vernale community)으로 총 9개군락과 1식재림으로 나누어졌다. 조사지의 식생은 피나물의 대형군락과 복수초군락, 긴산개나리군락 및 가침박달군락 등이 다른 곳에서 찾아보기 힘들 만큼 식물 분포학상 특이하며 그만큼 중요하므로 이를 특별히 보호해야 할 필요가 있다. 아울러 할미밀망, 큰잎산꿩의다리, 조팝나무는 한국특산식물이다. 흥미로운 점은 조사지가 비교적 낮은 곳에 위치하는데도 불구하고 할미밀망, 큰잎산꿩의다리, 피나물, 복수초 등 비교적 높은 곳에 분포하는 식물들이 이곳에 난다는 것은 국지적인 기후의 특수성 때문일 것으로 생각된다. 즉, 관촌 사선대 일대는 기온이 낮아서 옛부터 해빙이 늦게 되는 곳이라는 점이다. 또, 긴산개나리군락은 우리나라에서 가장 큰 자연군락이며 이곳이 분포의 남한계선이어서 이 군락지는 천연기념물로 지정되어 보호하고 있다. The flora of Saseon-dae, kwanchon, Imsil-gun was composed of 66 families, 145 genera, 177 species, 1 subspecies, 20 varieties, 4 forma and 202 taxa. The vegetaion was classified into 9 communities and 1 planted forest : Quercus serrata community, Exochorda serratifolia community, Carpinus tschonoskii community, Zelkova serrata community, Quercus acutissima community, Quercus aliena community, Forsythia saxatilis var. lanceolata community, Adonis amurensis community, Hylomecon vernale community and Pinus rigida plantation. Several ferns, for example, Pyrrosia linearifolia growing on the rock, Polystichum tsussimense, Camptosorus sibiricus, Asplenium trichomanes, Dryopteris lacera, and Dryopteris bissetiana, endemic species such as Clematis trichotoma, Thalictrum punctatum and Spiraea prunifolia var. simpliciflora were of great significance in terms of the geographical distribution of plants. Especial F. saxatilis var. lanceolata species are forming the biggest natural community and recognized southern boundary line of distribution in Korea, therefore, it should be protected with a special counterplan including designate as a precious natural monument.

Anti-inflammatory Effect of LFR on LPS-stimulated THP-1 Cells

정승기,Sul, Mu-Chang,Kim, Hong-Yeoul,Roh, Young-Lae,Jung, Hee-Jae,Jung, Sung-Ki 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.2

Background and Objective: Luffae Fructus Retinervus (LFR) is used for investigating symptoms of inflammation. We have evaluated the anti-inflammatory effect of LFR by analyzing the expression of pro-inflammatory cytokines. Materials and Methods : We differentiated THP-l cells into macrophage-like cells by treatment with PMA. Inflammation was induced by treatment with LPS and PMA. We determined the safe concentration of LFR by using the MTS and MTT assays and using PD 98059 as a negative control for comparison of the anti-inflammatory effect of LFR. Results : The MTS and MTT analysis showed that the cell survival rate was >80% within the LFR concentration range of 10-100 ng/ml and began to decrease to >80% at 1 ${\mu}g/ml$. By RT-PCR analysis, the gene expression of TNF-${\alpha}$, IL-8, TGF-${\beta}$, IL-6, IL-${\beta}$1, and IL-10 levels were down-regulated when monocyte-derived macrophages were treated with concentrations of LFR between 10 ng/mL and 100 ng/mL. Conclusion : We conclude that LFR exerts an anti-inflammatory effect by inhibiting the expression of pro-inflammatory activity. The results suggest a promising way to treat general inflammatory diseases.

Morgagni 탈장 : 1례 보고

오연희,이창욱,김승현,이성우,정병욱,이준희,박동일,권영무,신현종 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

Morgagni 탈장은 횡격막의 전내측 부위의 발달이상으로 열공을 통하여 장관이나 대망과 같은 복강내 구조물이 흉곽내로 빠져나가는 드문 질환으로 알려져 있다. 저자들은 호흡곤란을 주소로 내원하여 방사선학적 검사와 수술로 확진된 1례를 보고한다. Morgagni hernia is improperly located abdominal viscera into the thoracic cavity through the foramen of Morgagni which is a congenital defect at the anterornedial portion of diaphragm. We report a case of Morgagni hernia diagnosed by radiologic examination and operation.

일 농촌지역에서 발기부전의 유병률 및 상관 요인

홍진표,송해철,이무송,이창화,안준호,한오수,안태영,김성윤 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The purpose of this study was to investigate the prevalence of erectile dysfunction (ED) in a rural area of Korea and to examine the relationship between the prevalence and correlates of subjects. Method : This study was done as a part of the chronic disease survey of rural area by the Asan Foundation. Among 30 years or older population from Jung Eup, a rural area of Korea, 711 male subjects were sampled using a cluster probability sampling method. Trained interviewers visited and interviewed subjects aged 30 years or older with a structured interview. ED was categorized as 'none', 'mild', 'moderate', or 'severe' according to the ability to 'attain and/or maintain an erection satisfactory for sexual intercourse'. Response rate was 54.3% (N=386). Results : The age weighted prevalence of ED was 27.2% (minimal 14.1%, moderate 7.6%, severe 5.5%). Prevalence and severity increased with age. Liver disease and underweight were significantly (p<0.05) associated with ED. Smoking seemed to be correlated with ED, but did not reach statistically significant level. Conclusion : ED was highly prevalent in the rural community of Korea. Medical, sociodemographic, and lifestyle variables associated with ED may alert physicians to patients at risk for ED and offer insight to its etiology.