Chemotherapeutic Management in a Labrador Retriever with Cutaneous Nonepitheliotropic B-cell Lymphoma

홍일화,김민주,송중현,황태성,이희천,유도현,강병택,정동인 한국임상수의학회 2018 한국임상수의학회지 Vol.35 No.4

A 9-month-old, castrated, male Labrador Retriever was referred for generalized progressing cutaneous reddishmass lesions with bleeding, scale, crust, and pruritus. On the basis of histopathological findings and the results ofimmunochemical staining, cutaneous nonepitheliotropic B-cell lymphoma was identified. A cyclophosphamide–doxorubicin–vincristine–prednisolone (CHOP)-based chemotherapy regimen was initiated, and the patient initiallyshowed partial response to vincristine and L-asparaginase, but the cutaneous lesions progressed gradually. After thefirst cycle of the CHOP-based protocol, lomustine was administered instead. The cutaneous lesions showed partialresponse to lomustine, but the treatment did not stop the progression of cutaneous lymphoma. The patient was euthanizeddue to neurologic signs, including reduced consciousness and seizures, 53 days after initial presentation. The postmortemhistopathological examination showed systemic metastasis involving the lymph nodes, skin, kidney, ureter, liver, brain,temporal muscle, diaphragmatic muscle, conjunctiva, and oral cavity.

신문 빅 데이터를 바탕으로 본 4차 산업 스포츠

홍일화 한국스포츠산업경영학회 2020 한국스포츠산업경영학회지 Vol.25 No.3

People’s perceptions are also rapidly changing as the flow of society develops due to the fourth industrial revolution. Therefore, this study aims to present the overall basic data by deriving awareness and trends of ‘4th industrial sports’ using the news big data system, Big Kinds. In this study, analysis using big data news big data system was limited to a total of 4 years and 1 month from January 2016 to February 2020, and the ‘4th industrial sports’ keyword first mentioned in the 46th Davos World Economic Forum The study was conducted. As a result of the study, it was confirmed that the perception of sports in the 4th industry was very low in 2016, and then it began to emerge from 2017, and the contour of the 4th industrial sport type began to appear. It was confirmed that the words related to the convergence and convergence technology, the ‘sports convergence and convergence organization’, and the ‘4th industrial sport event’ are located in the core part of the key words. As the 1st ~ 3rd Industrial Revolution has increased efficiency for people through technological changes, it is judged that the 4th Industrial Revolution will lead from the finite era to the infinite era. The sports field incorporating the 4th industrial technology will also increase the connection with sports to people and change the quality of life and life. 4차 산업혁명으로 인해 사회의 흐름이 발전되면서 사람들의 인식 또한 빠르게 변화되고 있다. 이에 본 연구는 뉴스 빅 데이터 시스템인 Big Kinds를 활용하여 ‘4차 산업 스포츠’에 대한 인식과 트랜드를 도출하고 범주화하여 ‘4차 산업 스포츠’에 대한 현 시대의 전반적인 사회적 관심의 기초자료를 제시하고자한다. 자료 분석 기간은 제 46회 다보스 세계경제 포럼에서 ‘4차 산업’이 처음 언급된 2016년 1월부터 2020년 2월까지 총 4년 1개월로 한정하여 분석을 실시하였다. 연구결과 2016년 4차 산업에 대한 스포츠의 인식이 매우 저조한 경향을 보이다가 2017년부터 급상승하여 융ㆍ복합 적인 4차 산업 스포츠형태의 윤곽이 나타나기 시작한 것을 확인 할 수 있었으며, 키워드 연관 분석결과 ‘스포츠 융ㆍ복합 기술’, ‘스포츠 융ㆍ복합 주관단체’, ‘4차 산업 스포츠 이벤트’와 연관성이 있는 단어들이 주요단어 핵심부에 위치하고 있는 것을 확인할 수 있었다. 1~3차 산업혁명이 기술적 변화로 사람들에게 효율성을 높여 왔듯이 4차 산업혁명은 유한의 시대에서 무한의 시대로 이끌어 나갈 것이라 판단된다. 4차 산업 기술을 접목한 스포츠 분야도 마찬가지로 사람들에게 스포츠와의 연결성을 더욱 높여줄 것이며 삶의 질과 생활을 변화시킬 것이다.

대학 태권도 선수의 운동몰입과 운동중독 및 선수생활만족의 구조적 관계 - 시범선수와 겨루기선수의 조절효과를 중심으로

홍일화,강철우 한국무예학회 2016 무예연구 Vol.10 No.2

This research examined the structural relations and moderator effects of multi-group analysis according to taekwondo style between exercise commitment, addiction, and player life satisfaction of those participating in university taewondo team. The population of this research target was the players of competition and breaking demonstration participating in taekwondo competition in 2014 and 2015, and a total of 364 copies of questionnaires was set as valid samples. The verification of a measured model and a multi-group analysis of collected material was carried out by using Spss 18.0 and Amos 18.0. The questionnaires for the exercise commitment had been developed by Scanlan et al.,(1993) and Jung(1997), exercise addiction had been developed by Gang(2002) and Park(2012), and player life satisfaction had been developed by Hong(2009). The following results were obtained through the above research method and procedure. First, it appeared that exercise commitment has a significant positive influence on exercise addiction. Second, it appeared that exercise commitment has not a significant influence on player life satisfaction. Third, it appeared that exercise addiction has a significant positive influence on player life satisfaction. Forth, it appeared that moderator effects has a significant positive influence between exercise commitment and exercise addiction according to taekwondo style. 본 연구는 대학 태권도 겨루기와 시범 선수의 운동몰입과 운동중독 및 경기력의 관계를 파악하고, 시범과 겨루기 종목에 따른 선수의 운동몰입이 운동중독 및 선수생활만족에 미치는 영향을 조절하는 지를 규명하는데 목적이 있다. 본 연구대상은 대학 태권도 겨루기 및 시범 선수 400명을 자기평가기입법으로 조사하여 최종 364부가 사용되었다. 자료처리는 SPSS 18.0과 AMOS 18.0 프로그램을 통해서 검증하였으며, 다음과 같은 결론을 도출하였다. 첫 번째, 대학 태권도 선수의 운동몰입이 운동중독에 영향을 미칠 것이라는 가설Ⅰ을 분석한 결과 통계적으로 유의한 영향을 미치는 것으로 나타났다. 두 번째, 대학 태권도 선수의 운동몰입은 선수생활만족에 영향을 미칠 것이라는 가설Ⅱ를 분석한 결과 통계적으로 유의한 영향이 미치지 않았다. 셋째, 대학 태권도 선수의 운동중독은 선수생활만족에 영향을 미칠 것이라는 가설Ⅲ을 분석한 결과 통계적으로 유의한 영향을 미치는 것으로 나타났다. 넷째, 대학 태권도 시범선수와 겨루기 선수에 따라 운동몰입과 운동중독 및 선수생활만족의 관계는 조절효과가 있을 것이라는 가설Ⅳ를 분석한 결과 통계적으로 유의한 조절효과가 있는 것으로 나타났다. 결론적으로 태권도 종목 전반에 대한 운동몰입과 운동중독 및 운동만족 간의 관계를 확인하고 집단 간의 조절효과를 다양하게 파악할 필요가 있음을 실무적으로 제기하고 있다.

2단 감속 구조를 가진 인휠 감속기의 소음 저감에 관한 연구

홍일화(Ilhwa Hong),박소희(Sohee Park) 한국자동차공학회 2017 한국자동차공학회 학술대회 및 전시회 Vol.2017 No.11

In this study. the noise sources were identified and the noise were reduced for an In-wheel reduction system. To identify the noise sources, noise signals were measured by a microphone on a driver seat and these signals were analyzed with a waterfall plot. For this purpose, the gear mesh frequencies from the gear box of a reducer were not only investigated but noise sources of an electric motor were also examined. Furthermore, the gear transmission error using the analytical model were obtained to confirm the noise sources occurred by the wheel load during a vehicle motion. It was found that severe noise was generated in the gear system unstability by the wheel load applied to the gear box. In particular, the gear transmission error was dominant the lateral load occurred by a vehicle cornering. The severe noise could be reduced by a gear mesh stiffness modification.

사이클로이드 치형 감속기의 가공 및 조립 오차가 각도전달오차에 미치는 영향에 관한 연구

홍일화(Ilhwa Hong),김경록(Kyungrok Kim),김영환(Younghwan Kim),임흥순(Heungsoon Lim),정성현(SungHyun Jung) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.4

In this paper, parameters that have dominant effects on angular transmission error(A.T.E.) of reducer with cycloid tooth profile are identified, and reduction of the A.T.E. is experimentally confirmed by manufacturing error modification. For impact assessment of the A.T.E. on main components, series of the manufacturing errors are suggested and the A.T.E. is estimated in order to find dependent elements from equivalent analysis model. From the analytical result, we could make out that the A.T.E. is mainly caused by the manufacturing errors of hole and tooth profile in cycloid gear. It is also found that the A.T.E. is influenced by the assembly errors of hold flange and output shaft in carrier. It is experimentally verified that these influence factors have considerable effect on the A.T.E.

수술용 로봇의 절삭 정도 개선을 위한 기구 설계에 관한 연구

홍일화(Il Hwa Hong),김진웅(Jin Woong Kim),최진혁(Jin Hyeok Choi),임흥순(Heung Soon Lim),정성현(Sung Hyun Jung) 대한기계학회 2011 대한기계학회 춘추학술대회 Vol.2011 No.6

태권도 공연 평가요인과 관람관여도 및 관람행동의도 간에 구조적 관계모형의 연구

홍일화(Hong, Il-Hwa) 한국체육과학회 2017 한국체육과학회지 Vol.26 No.2

The purpose of this study was to identify the structural causal relationship model among taekwondo performance assessment factor, view involvement, and viewing behavior intention of the viewer of taekwondo performance. The subjects of this study were 355 viewers who had watched show of taekwondo performance by using SPSS 21.0 and AMOS 21.0 programs. To perform this empirical study, the data for the present study were collected from one firms through questionnaire and all measures were self-administred by respondents. To analyze this data, reliability test and factor analysis was employed to test the reliability and validity, and correlation analysis was adopted to analyze the relationship between variables, and structural equation model analysis was used to identify the causal relationship of taekwondo performance viewerers on view involvement and behavior intention. The questionnaires for taekwondo performance assessment factor had been developed by Kim(2009), Kim(2008) and Lee(2011), view involvement had been developed by Ko(2009), Kim et al.,(2007) and chae(2002), and viewing behavior intention had been developed by Park(2013), and Jang(2011). The results were summarized as follow. First, it was showed that taekwondo performance assessment factor have a significant positive influence on view involvement partially. Second, it was showed that view involvement has a significant influence on viewing behavior intention.

The Ossifying Epulis Accompanying Multi-Nucleated Giant Cells in a Dog

II-Hwa Hong(홍일화),Won-Il Jeong(정원일),Young-Sook Son(손영숙),Jin-Kyu Park(박진규),Hai-Jie Yang(양해걸),Dong-Wei Yuan(위엔동웨이),Moon-Jung Goo(구문정),Hye-Rim Lee(이혜림),Kyu-Shik Jeong(정규식) 한국생명과학회 2007 생명과학회지 Vol.17 No.11

11살된 암컷 개, 요크셔 테리어의 발치된 잇몸에서 치은종이 관찰 되었다. 치은종은 조직병리학적 특징에 따라 섬유소성, 골화성, 극세포성 그리고 거대세포성 치은종으로 나눌 수 있으며, 본 증례의 경우 광학현미경학적 관찰결과 골화성 치은종으로 진단되었다. 그러나 특이하게도 골화성 치은종 병변과 함께 몇몇의 거대세포가 관찰 되었다. 거대세포는 파골세포와 유사한 형태를 가지고 있으며, 더욱이 거대세포성 치은종의 경우 발치한 잇몸에서 주로 발생하는 것으로 보고되고 있다. 그러므로 골화성 치은종에 발생한 거대세포의 출현이유를 두 가지로 제시할 수 있겠다. 하나는, 치은종의 섬유모세포가 분화되어 형성된 골 성분을 거대세포가 파골세포처럼 탐식하기 위해 출현한 것으로 가정할 수 있으며, 다른 한편으로는 골화성 치은종의 주요 발생원인인 만성 치은염과 발치로 인한 손상 및 염증 등의 거대세포성 치은종의 발생 원인이 복합적으로 작용하여 발생한 혼합 치은종으로 판단할 수 있겠다. 이와 같은 이유로 거대세포가 골화성 치은종에 출현할 가능성이 있다고 판단되어지지만 현재까지 이와 같은 보고는 없었으며, 또한 턱에서 발생하는 거대세포를 포함하는 병변의 발병기전은 아직까지 불분명한 상태이므로 본 증례가 발병기전 연구에 도움이 될 것으로 사료된다. An epulis was occurred on gingiva of 11-year old female dog, Yorkshire terrier. Our case had feature of ossifying epulis but there were a few multi-nucleated giant cells (MGCs). MGCs had osteoclast-like appearance and giant cell epulis usually appears at the site of tooth extraction. Therefore, we suggest that appearance of MGCs in our case may be due to phagocytosis pre-formed osteoid/bone or our case may be mixed epulides of ossifying and giant cell epulis by mixed stimulation of chronic gingivitis and trauma and in flammation by tooth extraction. Thus, MGCs have possibility enough to appear in ossifying epulis, but ossifying epulis accompanying MGCs has not been reported. Therefore, our case may deserves an attention as an unique case and will be helpful to study pathogenesis of giant cell containing lesion of the jaw.

일반 국도중심의 3차원 수치표고모형 제작 및 동영상 시뮬레이션 연구

연상호,홍일화 대한교통학회 2002 대한교통학회 학술대회지 Vol.42 No.-

Effect of Endoscopic Forceps on the Quality of Duodenal Mucosal Biopsy in Healthy Cats

원진희,홍일화,장효미,엄나영,지초희,정해원,강병택,정동욱,정동인 한국임상수의학회 2015 한국임상수의학회지 Vol.32 No.2

Based on the results of previous studies, endoscopic biopsy sample’s quality has a major impact on its adequacy for histopathology, and that the nature of the biopsy forceps can influence the specimen quality. The present study compared the effects of three different types of endoscopic biopsy forceps and two different operators on sample quality and adequacy for histopathology in three healthy cats. Every biopsy was performed between the major papilla and caudal duodenal flexure, and each operator performed five biopsies with each type of forceps on each cat, for a total of 90 biopsies. One pathologist evaluated the quality and adequacy of the obtained samples. Biopsies performed with large-cup forceps provided heavier and longer samples than the standard round forceps. With the same size forceps, the presence of alligator teeth had no effect on sample quality or adequacy for histopathological examination and assessment. Based on the results of the present study, although the standard round forceps could be used to obtain adequate samples for histopathology, large-cup forceps such as the standard oval and alligator jaw type have the advantage of obtaining high quality endoscopic samples.